ʻO ʻoe a i ʻole kekahi āu i ʻike ai e mālama ʻia ana paha i ka maʻi kanesa. I loko o kēia mālama ʻana, ʻoiai ka chemotherapy, ua luku koke ʻia nā hunaola kanesa. ʻOiai he mea maikaʻi kēia, i ka wā e luku ʻia ai kēia mau hunaola, hōʻiliʻili nui ʻia nā mea i loko o lākou, ʻoiai kahi kemika i kapa ʻia ʻo uric acid , i loko o ke koko. ʻAʻole maikaʻi kēia piʻi koke ʻana o ka uric acid no ko kākou mau puʻupaʻa. No laila, i ia mau hihia, hoʻohana nā kauka i kahi lāʻau kūikawā i kapa ʻia ʻo 'Rasburicase'. I kēia lā, e kamaʻilio kākou e pili ana i kēia lāʻau ma nā ʻōlelo maʻalahi.
He aha kēia Rasburicase? He aha kāna hana maoli?
I ka ʻōlelo maʻalahi, ʻo Rasburicase (ರಾಸ್-ಬೀರೀ-ಕ್ಸ್) kahi lāʻau lapaʻau e kaohi ana i ka nui o ka uric acid i loko o ko kākou koko. Hoʻohana nui ʻia ia e hōʻemi a pale i ka piʻi koke ʻana o nā pae uric acid i loko o ke kino ma muli o ka mālama ʻana i ka maʻi kanesa.
E noʻonoʻo i ko kākou mau kīʻaha koko e like me ke alanui. Ke luku ʻia nā hunaola kanesa, hoʻokumu ka waikawa uric i ka nui o ke kaʻa ma kēia alanui. Hiki i kēia kaʻa ke hoʻopilikia i ka hana o ke kino koʻikoʻi loa, ʻo ia hoʻi nā puʻupaʻa. Hana ka lāʻau lapaʻau ʻo `Rasburicase` e like me ka mākaʻi kaʻa, e hoʻopau ana i kēia pilikia kaʻa o ka waikawa uric a hoʻololi iā ia i loko o kahi kemika ʻē aʻe e hiki ke hoʻokuʻu maʻalahi ʻia mai ke kino. ʻAe kēia i ka mālama ʻana i ka maʻi kanesa e hoʻomau me ka ʻole o ka hōʻeha ʻana i nā puʻupaʻa.
ʻO ka maʻamau, hele mai kēia lāʻau lapaʻau ma ke ʻano he wai (infusion) i hāʻawi ʻia i loko o kahi aa. ʻO ia hoʻi, hāʻawi ʻia i loko o ke kino ma nā ʻāpana liʻiliʻi, e like me ka saline. Hāʻawi ʻia ia ma kahi haukapila a i ʻole ke keʻena lapaʻau ma lalo o ka nānā ʻana a nā kauka a me nā limahana kahu maʻi. He inoa kaulana ʻo 'Elitek' no kēia lāʻau lapaʻau.
Nā mea āu e haʻi aku ai i kāu kauka ma mua o ka lawe ʻana i kēia lāʻau lapaʻau
He lāʻau ikaika loa ʻo Rasburicase. No laila, he mea nui loa e hoʻomaopopo i kāu kauka e pili ana i kou mōʻaukala olakino piha ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau. He mea nui loa ia e haʻi iā lākou inā loaʻa iā ʻoe kekahi o kēia mau kūlana:
| Kūlana olakino a i ʻole mōʻaukala | No ke aha he mea nui? (Wehewehe maʻalahi) |
|---|---|
| Ka hemahema o ka G6PD | He kūlana hoʻoilina kēia e pili ana i kahi enzyme i loko o nā hunaola koko. Inā hāʻawi ʻia ka Rasburicase i nā poʻe me kēia kūlana, hiki i nā hunaola koko ʻulaʻula ke haki a hoʻoulu i ka anemia koʻikoʻi. No laila he mea nui loa kēia. |
| Anemia a i ʻole ka mōʻaukala o ka hāʻawi koko | Inā loaʻa iā ʻoe ka anemia a i ʻole ua loaʻa mua iā ʻoe nā hoʻoili koko, he mea nui e hoʻomaopopo i kāu kauka. |
| Nā ʻano maʻi like ʻole (Allergies) | E hōʻoia e haʻi i kāu kauka inā loaʻa iā ʻoe kekahi mau maʻi allergies i ka rasburikase, ka hū, ka mannitol, nā lāʻau lapaʻau ʻē aʻe, nā meaʻai, a i ʻole nā mea hoʻoluʻu. |
| Hāpai a i ʻole e hoʻāʻo ana e hāpai | Inā hāpai ʻoe a i ʻole e hoʻolālā ana e hāpai, he mea nui loa ia e haʻi aku i kāu kauka. |
| Ka hānai ʻana i ka waiū umauma | Pono ʻoe e pale i ka hānai waiū ʻana i ka wā e lawe ana i kēia lāʻau lapaʻau a no 2 mau pule ma hope o ka hoʻōki ʻana. No laila, inā he makuahine hānai waiū ʻoe, e haʻi pū i kāu kauka e pili ana i ia mea. |
Nā mea e makaʻala ai i ka wā e hoʻohana ai i kēia lāʻau lapaʻau
E nānā pono loa nā limahana lapaʻau iā ʻoe i ka wā e hāʻawi ʻia ai kēia lāʻau lapaʻau iā ʻoe.
- Nā hoʻāʻo koko: I ka wā o ka mālama ʻana, pono ʻoe e loaʻa i nā hoʻāʻo koko maʻamau e nānā i kāu mau pae uric acid, pehea ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau, a inā he mau hopena ʻaoʻao. He mea maʻamau kēia, no laila mai hopohopo.
- Nā lāʻau lapaʻau ʻē aʻe: E hāʻawi i kāu kauka i kahi papa inoa piha o nā lāʻau lapaʻau ʻē aʻe, nā huaora, nā lāʻau lapaʻau lāʻau, a me nā mea hoʻohui āu e lawe nei. Hiki i kekahi ke launa pū me kēia lāʻau lapaʻau.
- No nā keiki: Hāʻawi ʻia kēia lāʻau lapaʻau i kekahi manawa i nā keiki e like me ka ʻōpio o 1 mahina. Eia nō naʻe, pono e mālama ʻia nā hana palekana kūikawā. Inā ʻoe e hāʻawi ana i kēia lāʻau lapaʻau i kāu keiki, e kamaʻilio me kāu kauka pediatric e pili ana i ia mea.
ʻOiai ua hāʻawi ʻia kēia lāʻau lapaʻau ma kahi haukapila ma lalo o ka nānā pololei ʻana a nā kauka a me nā kahu maʻi, ʻaʻole pono ʻoe e hopohopo e pili ana i ka overdose. Inā manaʻo ʻoe i kekahi ʻoluʻolu ʻole ma kekahi ʻano, e hoʻomaopopo koke i ke kahu maʻi a i ʻole ke kauka. E hana lākou i nā hana e pono ai no kēlā. Inā kānalua ʻoe i kekahi lāʻau make ʻē aʻe, hiki iā ʻoe ke kelepona i ke Kikowaena ʻIke Lahui no nā Lāʻau Make ma ka Halemai Lahui ʻo Colombo no ka ʻōlelo aʻoaʻo.
He aha nā hopena ʻaoʻao e hiki ke loaʻa iā Rasburicase?
E like me nā lāʻau lapaʻau āpau, hiki i ka `Rasburicase` ke hana i nā hopena ʻaoʻao i kekahi poʻe. Eia naʻe, ʻaʻole i loaʻa i nā kānaka a pau. ʻO ka mea nui loa, ʻo ia ka hōʻike koke ʻana i nā hōʻailona.
| Ka hoʻokaʻawale ʻana o nā hopena ʻaoʻao | |
|---|---|
| Nā hopena ʻaoʻao koʻikoʻi e pono ʻoe e hōʻike koke i kāu kauka a kahu maʻi paha | |
| Nā hopena alerika | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, nā lehelehe a i ʻole ke alelo. |
| Nā pilikia hanu | Paʻakikī ka hanu ʻana, ʻeha ka umauma a i ʻole ka ʻūmiʻi. |
| Nā pilikia kahe koko | Nā lehelehe a i ʻole nā kui lima polū, ka puʻuwai wikiwiki a ʻano ʻole paha, ka nāwaliwali, ke koko haʻahaʻa, ka melemele o nā maka a i ʻole ka ʻili. |
| Nā hōʻailona koʻikoʻi ʻē aʻe | Nā ʻūlū, luhi loa a luhi paha, huikau. |
| Nā hopena ʻaoʻao ʻaʻole i koʻikoʻi pinepine, akā pono e hōʻike ʻia i ke kauka inā hoʻomau lākou | |
| |
ʻAʻole i loko o kēia papa inoa nā hopena ʻaoʻao āpau, no laila inā loaʻa iā ʻoe kekahi mea ʻē, mai makaʻu e kamaʻilio me kāu kauka e pili ana i ia mea.
Leka Lawe-Home
- He lāʻau lapaʻau kūikawā ʻo 'Rasburicase' i hāʻawi ʻia ma ka haukapila e hōʻemi i ka nui o ka uric acid i loko o ke koko e piʻi ana ma muli o ka mālama ʻana i ka maʻi kanesa.
- Ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau, e hōʻoia e haʻi i kāu kauka e pili ana i kou hemahema G6PD, nā maʻi allergies, a me nā kūlana olakino ʻē aʻe.
- He mea nui nā hoʻāʻo koko pinepine i ka wā o ka mālama ʻana.
- E hoʻomaopopo koke i kāu kauka a kahu maʻi paha inā loaʻa iā ʻoe kekahi mau hōʻailona maʻi koʻikoʻi, e like me ka paʻakikī o ka hanu ʻana, ka ʻulaʻula o ka ʻili, a i ʻole ka pehu ʻana o ka maka.
- E pale i ka hānai waiū ʻana i ka wā e lawe ana i kēia lāʻau lapaʻau a no 2 mau pule ma hope o ka hoʻōki ʻana.
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