Hiki i ka lāʻau lapaʻau āu e lawe nei ke hoʻoweliweli i ke ola? E kamaʻilio kākou e pili ana i ka Serotonin Syndrome

He kanaka ʻoe e lawe ana i ka lāʻau lapaʻau no ke kaumaha, migraines, a i ʻole ka ʻeha nui? A i ʻole ke lawe nei ʻoe i ka lāʻau lapaʻau mai kekahi mau kauka no ka maʻi like? A laila e lilo kēia moʻolelo i mea nui loa iā ʻoe. I kēia lā, ke kamaʻilio nei mākou e pili ana i kahi kūlana e hiki ke kū i loko o ko mākou kino ma muli o kekahi mau ʻano lāʻau lapaʻau, hiki ke hoʻoweliweli i ke ola inā ʻaʻole maopopo pono. Kāhea mākou i kēia ʻo 'Serotonin Syndrome' . Mai hopohopo, inā ʻike pono mākou i kēia, hiki iā mākou ke pale aku i kahi pilikia nui.

I ka ʻōlelo maʻalahi, he aha ka Serotonin Syndrome?

I mea e hoʻomaopopo ai i kēia, pono mua kākou e ʻike i ke ʻano o ka 'Serotonin'. E noʻonoʻo iā ia he ʻelele liʻiliʻi e lawe ana i nā leka ma waena o ko kākou lolo a me ke koena o ko kākou kino. I ka lāʻau lapaʻau, kapa mākou i kēia mau ʻelele kemika he 'neurotransmitters'. He neurotransmitter koʻikoʻi nō hoʻi ʻo Serotonin no ko kākou kino, e kaohi ana i nā mea he nui e like me ko kākou ʻano, ka hiamoe, a me ka makemake.

ʻO ka maʻamau, ke lawe ʻoe i ka lāʻau lapaʻau i kuhikuhi ʻia e ke kauka, ua kaulike ke kiʻekiʻe o ka serotonin i loko o ke kino. Eia nō naʻe, inā no kekahi kumu e piʻi nui ai kēia kemika i kapa ʻia ʻo serotonin i loko o ko mākou kino , ʻo ia hoʻi, inā hōʻiliʻili ia i kahi nui i hiki ʻole i ke kino ke mālama, ʻo ka pane a ko mākou kino iā ia ua kapa ʻia ʻo 'serotonin syndrome'. Hiki i kēia ke lilo i hopena weliweli i hoʻokumu ʻia e kahi ʻano lāʻau lapaʻau (drug reaction).

ʻO wai ka mea i ʻoi aku ka paʻakikī o ka loaʻa ʻana o kēia maʻi?

ʻO ka ʻoiaʻiʻo, ʻo kēlā me kēia kanaka o kēlā me kēia makahiki e hoʻohana ana i nā lāʻau lapaʻau, nā mea hoʻohui, a i ʻole nā ​​​​lāʻau lapaʻau kū ʻole i ke kānāwai e hoʻopilikia i nā pae serotonin e pilikia ana. ʻIke pinepine ʻia kēia ʻano ma nā kūlana e like me kēia:

• Ke hoʻomaka ʻana i kahi lāʻau lapaʻau hou: Ke hoʻomaka koke ʻoe i kahi lāʻau lapaʻau hou e hoʻonui ai i nā pae serotonin.
• I ka hoʻonui ʻana i ka nui o ka lāʻau lapaʻau: Inā hoʻonui kāu kauka i ka nui o ka lāʻau lapaʻau āu e lawe nei.
• Ke hoʻohana pū ʻia kekahi mau lāʻau lapaʻau: ʻO kēia ke kumu weliweli loa a maʻamau. E noʻonoʻo, he ʻeha kou mau hono. Lawe ʻoe i kahi lāʻau hoʻopau ʻeha mai kekahi kauka no ia mea. I kēia manawa, no kou hopohopo iki ʻana, ʻike ʻoe i kekahi kauka ʻē aʻe a lawe pū i ka lāʻau lapaʻau no ia mea. Akā, ʻaʻole ʻoe e haʻi i ke kauka mua e pili ana i ka lua o ka lāʻau lapaʻau, ʻaʻole hoʻi i ke kauka ʻelua e pili ana i ka lāʻau lapaʻau mua. ʻO kēia ka manawa e loaʻa ai ka manawa kūpono e hoʻohana pū me ka ʻike ʻole i ʻelua mau lāʻau hoʻonui serotonin a hoʻoulu i kēia kūlana.
• Inā lawe ʻoe i ka nui o ka lāʻau lapaʻau: Inā lawe ʻoe i ka lāʻau lapaʻau ma mua o ka nui i kuhikuhi ʻia, me ka manaʻo a i ʻole ka ulia.

He aha nā hōʻailona? Pehea mākou e ʻike ai i kēia?

Hiki ke ʻokoʻa nā hōʻailona o ka serotonin syndrome mai kēlā kanaka a kēia kanaka. Hiki i kekahi poʻe ke ʻike i nā hōʻailona palupalu loa, aʻo kekahi poʻe e ʻike i nā hōʻailona koʻikoʻi a hoʻoweliweli i ke ola. Hoʻomaka pinepine kēia mau hōʻailona i loko o kekahi mau hola o ka lawe ʻana i kahi lāʻau hou a i ʻole ka hoʻololi ʻana i ka dosage.

No ka maʻalahi o ka hoʻomaopopo ʻana, e puʻunaue kākou i kēia mau hōʻailona i ʻekolu mau māhele.

He aha kēia mau lāʻau lapaʻau e hoʻonui ai i nā pae serotonin?

He lōʻihi iki kēia papa inoa, akā he mea nui loa ia no kou palekana e makaʻala i kēia.

Nā lāʻau hoʻēmi kaumaha

ʻO kēia nā lāʻau lapaʻau i pili pinepine ʻia me ka serotonin syndrome. Kiʻekiʻe loa ka pilikia ke lawe ʻia kēia mau mea me nā lāʻau lapaʻau ʻē aʻe (e.g., nā lāʻau migraine).

• Nā SSRI (nā mea pale i ka hoʻihoʻi hou ʻana o ka serotonin koho): Nā lāʻau lapaʻau e like me Fluoxetine, Sertraline, Citalopram, Escitalopram, Paroxetine.
• Nā SNRI (Serotonin-norepinephrine reuptake inhibitors): Nā lāʻau lapaʻau e like me Venlafaxine, Duloxetine, Desvenlafaxine.
• Nā lāʻau antidepressants Tricyclic: Nā lāʻau lapaʻau e like me Amitriptyline, Nortriptyline, Imipramine.
• MAOIs (Monoamine oxidase inhibitors): ʻOiai ʻaʻole hoʻohana pinepine ʻia kēia mau mea, hāʻawi ʻia lākou i kekahi mau hihia.

Nā lāʻau lapaʻau ʻē aʻe

• Nā lāʻau lapaʻau no ka ʻeha nui: Nā lāʻau hoʻopau ʻeha e like me Tramadol, Pethidine (Meperidine), Fentanyl, a me Methadone.
• Lāʻau kuni: Aia kekahi mau syrup kuni i loaʻa mai nā hale kūʻai lāʻau lapaʻau i kahi mea i kapa ʻia ʻo Dextromethorphan . Hiki i kēia ke hoʻopilikia i nā pae serotonin.
• Nā lāʻau lapaʻau migraine: Nā lāʻau lapaʻau Triptan e like me Sumatriptan lāua ʻo Rizatriptan.
• Nā lāʻau lapaʻau no ka luaʻi ʻana: Nā lāʻau lapaʻau e like me Metoclopramide a me Ondansetron.
• Kekahi mau lāʻau antibiotic: ʻO ka lāʻau antibiotic linezolid.
• Lāʻau hoʻomalu manaʻo: Lithium.

Nā mea ʻē aʻe

• Nā mea hoʻohui lāʻau lapaʻau: Nā mea e like me ka wort a St. John a me Ginseng.
• Nā lāʻau lapaʻau kū ʻole i ke kānāwai: Nā mea e like me Ecstasy (MDMA), LSD, Cocaine, Amphetamines.

Mai hopohopo i kēia papa inoa. ʻAʻole e loaʻa i nā kānaka a pau kēia maʻi ma hope o ka lawe ʻana i kekahi o kēia mau lāʻau lapaʻau. Kū mai ka pilikia ke hoʻohana pū ʻoe i kekahi o kēia mau mea, hoʻonui i ka nui, a inā paha he maʻalahi kou kino iā lākou.

Pehea e ʻike ai ke kauka i kēia?

ʻAʻohe hoʻāʻo koko kikoʻī a scan paha e hōʻoia i ka serotonin syndrome. E ʻike ke kauka i ke kūlana ma muli o kekahi mau kumu:

1. Kou mau hōʻailona: E hoʻolohe pono i kou manaʻo.

2. Hoʻokolokolo kino: E nānā ʻia kou helu puʻuwai, ke koko, ka mahana o ke kino, a me ke kūlana o nā ʻiʻo.

3. Papa inoa o nā lāʻau lapaʻau āu e lawe nei: ʻO kēia ka mea nui loa.

Eia kekahi, hiki iā ʻoe ke hana i nā hoʻāʻo koko a me ka mimi, kahi X-ray umauma, a i ʻole kahi scan CT e hōʻoia ʻaʻohe ou mau kūlana ʻē aʻe (e laʻa me nā maʻi) e hoʻoulu nei i nā hōʻailona like.

He aha nā lāʻau lapaʻau no kēia?

Aia ka lāʻau lapaʻau i ke koʻikoʻi o kāu mau hōʻailona.

• Inā loaʻa iā ʻoe nā ʻōuli iki: ʻO ka lāʻau maʻamau, ʻo ia ke hoʻōki i ka lawe ʻana i ka lāʻau i hoʻokumu i nā ʻōuli. E hoʻopau loa kēia i nā ʻōuli i loko o 24-72 mau hola.
• Inā loaʻa iā ʻoe nā hōʻailona kaulike: E mālama ʻia ʻoe i loko o ka haukapila a nānā ʻia no 24 mau hola ma ka liʻiliʻi. I loko o kēia manawa, e hāʻawi ʻia ʻoe i ka saline (nā wai IV) a me nā lāʻau lapaʻau e like me benzodiazepines no ka hopohopo.
• Inā loaʻa iā ʻoe nā hōʻailona koʻikoʻi: He pilikia olakino kēia. E hoʻokomo ʻia ʻoe i ka ʻāpana mālama koʻikoʻi (ICU) a hāʻawi ʻia i ka lāʻau lapaʻau e like me ke kākoʻo no nā pilikia hanu, ka kaohi ʻana i ke kuni kiʻekiʻe, a me nā lāʻau lapaʻau e kaohi i ka helu o ka puʻuwai a me ke koko. I kekahi manawa, hiki ke hāʻawi ʻia kahi lāʻau lapaʻau i kapa ʻia ʻo Cyproheptadine, ka mea e ālai ana i ka hana o ka serotonin.

Pehea lā e hiki ai iā kākou ke pale aku iā kākou iho mai kēia kūlana?

Aia kekahi mau mea maʻalahi akā nui loa e hiki ai iā kākou ke hana e palekana mai kēia kūlana pōpilikia.

1. E aʻo iā ʻoe iho e pili ana i kāu mau lāʻau lapaʻau: E mālama i kahi moʻolelo o ka inoa, ka nui o ka lāʻau, a me ke kumu o kēlā me kēia lāʻau lapaʻau āu e lawe ai.

2. E haʻi i kēlā me kēia kauka i nā kikoʻī piha: Inā e mālama ʻia ana ʻoe e kekahi mau kauka, e hōʻoia e haʻi i kekahi kauka e pili ana i nā lāʻau lapaʻau i kuhikuhi ʻia e nā poʻe ʻē aʻe.

3. Mai ho'ōki i ka lawe ʻana i ka lāʻau lapaʻau me ka ʻole o ke nīnau ʻana i kāu kauka: ʻOiai inā ʻoe e manaʻo nei i kekahi ʻano ʻeha, mai hoʻōki i ka lawe ʻana i ka lāʻau lapaʻau a hoʻololi paha i ka nui me ka ʻole o ke kamaʻilio ʻana me ke kauka.

4. E makaʻala i ke kūʻai ʻana i ka lāʻau lapaʻau mai ka hale kūʻai lāʻau lapaʻau: I ke kūʻai ʻana i ka lāʻau lapaʻau no nā mea e like me ke kuni a me ke anu, e noi i kahi lāʻau lapaʻau e kūpono me ka lāʻau lapaʻau āu e lawe nei.

5. E makaʻala i nā hōʻailona: E makaʻala pono i nā loli i kou kino, ʻoiai ke hoʻomaka ʻana i kahi lāʻau lapaʻau hou a i ʻole ka hoʻonui ʻana i ka nui.