I kēia lā, e kamaʻilio mākou e pili ana i kahi lāʻau lapaʻau kūikawā i hāʻawi ʻia i kekahi e hakakā nei i ka maʻi kanesa. Ua hāʻawi ʻia paha kēia lāʻau lapaʻau iā ʻoe a i ʻole kekahi āu i ʻike ai, i kapa ʻia ʻo Vemurafenib , e kāu kauka. No laila, i kēia lā e kamaʻilio kikoʻī mākou e pili ana i ke ʻano o kēia lāʻau lapaʻau, pehea e hoʻohana ʻia ai, a me nā mea e pono ai mākou e makaʻala nui.
He aha kēia lāʻau lapaʻau i kapa ʻia ʻo Vemurafenib?
I ka ʻōlelo maʻalahi, ʻo Vemurafenib kahi lāʻau lapaʻau e kuhikuhi ana i kekahi mau protein i loko o nā hunaola kanesa a kāohi iā lākou mai ka ulu ʻana. I ka pololei, hana ia ma ke ʻano he lāʻau lapaʻau i kuhikuhi ʻia . Hoʻohana nui ʻia ia e mālama i kahi ʻano maʻi ʻili i kapa ʻia ʻo melanoma . Hoʻohana ʻia hoʻi ia e mālama i kahi maʻi laha ʻole i kapa ʻia ʻo ka maʻi Erdheim-Chester .
E hoʻomanaʻo, hiki i nā kauka ke hoʻohana i kēia lāʻau lapaʻau no nā kūlana ʻē aʻe i kekahi manawa, no laila inā he mau nīnau kāu, ʻoi aku ka maikaʻi o ka nīnau ʻana i kāu kauka a mea kūʻai lāʻau paha.
ʻO Zelboraf ka inoa inoa maʻamau no kēia lāʻau lapaʻau.
He aha nā mea e pono iaʻu e haʻi aku i ke kauka ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau?
Ma mua o kou hoʻomaka ʻana e lawe iā Vemurafenib, he mea nui loa ia e haʻi i kāu kauka e pili ana i kou mōʻaukala olakino. He mea nui loa ia e haʻi i kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau kūlana:
- Inā he mau maʻi maka kou a i ʻole nā pilikia ʻike maka
- Inā he maʻi puʻuwai kou
- Inā ua loaʻa iā ʻoe kahi puʻuwai puʻuwai kūpono ʻole ma mua
- Inā ua ʻike mua ʻia ʻoe me ka haʻahaʻa o ka calcium koko, magnesium, a i ʻole ka pae potassium
- Inā he maʻi puʻupaʻa kou
- Inā loaʻa iā ʻoe ka maʻi akepaʻa
- Inā ua loaʻa iā ʻoe i kēia manawa a i ʻole ke hele nei ʻoe i ka radiation therapy
- Inā ua loaʻa iā ʻoe kahi hopena maʻi a i ʻole kahi hopena kūikawā iā Vemurafenib, nā lāʻau lapaʻau ʻē aʻe, nā meaʻai, nā mea hoʻoluʻu, a i ʻole nā mea mālama.
- Inā ʻoe e hoʻāʻo nei e hāpai a i ʻole ke hāpai nei i kēia manawa (he mea nui loa kēia)
- Inā he makuahine hānai ʻoe (he mea nui nō hoʻi kēia)
Ma ka haʻi pololei ʻana aku iā ʻoe i kēia mau mea e hiki ai i ke kauka ke hoʻoholo inā kūpono kēia lāʻau lapaʻau iā ʻoe a ʻaʻole paha, a me nā hana palekana āu e pono ai e hana.
Pehea pololei kaʻu e hoʻohana ai i kēia lāʻau lapaʻau?
Loaʻa kēia lāʻau lapaʻau ma ke ʻano he mau papa. Pono ʻoe e lawe ia mea ma ka waha me ke aniani wai. E hahai i nā kuhikuhi ma ka lepili kauoha i hāʻawi ʻia iā ʻoe e kāu kauka a kauka lāʻau paha.
- Mai uhaʻi, kuʻi, a nau paha i kēia mau papa. E ale holoʻokoʻa i ka papa.
- Hiki iā ʻoe ke lawe i kēia me ka meaʻai a me ka ʻole. Eia nō naʻe, inā ʻeha kou ʻōpū, ʻoi aku ka maikaʻi o ka lawe ʻana me ka meaʻai.
- E lawe i ka lāʻau lapaʻau i ka manawa kūpono, ma ka nui wale nō i kuhikuhi ʻia e kāu kauka. Mai lawe ʻoi aku ma mua o ka nui i kuhikuhi ʻia.
- ʻO ka mea nui loa, mai ho'ōki koke i ka lawe ʻana i kēia lāʻau me ka ʻole o ke aʻo ʻana a kāu kauka.
- ʻO ka hapa nui o ka manawa, lawe ʻia kēia mau lāʻau lapaʻau ma kahi o 12 mau hola ka mamao. ʻO ia hoʻi, inā ʻoe e lawe iā lākou i ke kakahiaka, pono ʻoe e lawe i ka mahele lāʻau aʻe i ka pō.
Ke loaʻa iā ʻoe kāu lāʻau lapaʻau, e hāʻawi ka hale kūʻai lāʻau lapaʻau iā ʻoe i kahi puke alakaʻi kūikawā (MedGuide) . E heluhelu pono i kēia puke i kēlā me kēia manawa āu e loaʻa ai kahi lāʻau lapaʻau hou. Loaʻa iā ia ka nui o nā ʻike koʻikoʻi nāu.
Inā ʻoe e hāʻawi ana i kēia lāʻau lapaʻau i nā keiki, pono ʻoe e kamaʻilio me ke kauka pediatric e pili ana i ia mea a mālama pono.
He aha kāu e hana ai inā lawe nui ʻoe i ka lāʻau lapaʻau?
Inā manaʻo ʻoe ua lawe nui ʻoe i kēia lāʻau lapaʻau ma ke kuhihewa, e kāhea koke i kahi kikowaena hoʻomalu lāʻau make a i ʻole ka lumi pilikia kokoke loa.
Ua kuhikuhi ʻia kēia lāʻau lapaʻau nou wale nō. Mai kaʻana like me kekahi.
He aha kāu e hana ai inā e poina ʻoe i kahi mahele o ka lāʻau lapaʻau?
Inā ʻoe e poina i kahi lāʻau lapaʻau, e lawe koke iā ia i kou hoʻomanaʻo ʻana. Eia nō naʻe, inā ʻoi aku ka liʻiliʻi ma mua o 4 mau hola a hiki i kāu lāʻau lapaʻau aʻe i hoʻonohonoho ʻia, e hōʻalo i ka lāʻau lapaʻau i poina. Akā, e lawe i kāu lāʻau lapaʻau aʻe i ka manawa i hoʻonohonoho ʻia. Mai lawe pālua i ka lāʻau lapaʻau.
He aha nā mea ʻē aʻe e hiki ke launa pū me kēia lāʻau lapaʻau?
He mea nui loa kēia. Hiki iā Vemurafenib ke launa pū me kekahi mau lāʻau lapaʻau ʻē aʻe āu e lawe nei. Inā hana kēia, hiki ke hoʻonui ʻia nā hopena ʻaoʻao a i ʻole e emi iho ka pono o ka lāʻau lapaʻau.
Mai lawe iā Vemurafenib me nā lāʻau lapaʻau e hiki mai ana:
- ʻO Cisapride
- ʻO Dronedarone
- ʻO Fluconazole
- Pimozide
- Posaconazole
- ʻO Saquinavir
- ʻO Thioridazine
Eia kekahi, hiki i nā lāʻau lapaʻau ke launa pū me Vemurafenib:
- Nā lāʻau lapaʻau antiviral no ka maʻi HIV a i ʻole AIDS
- Nā mea i loaʻa ka caffeine (e nīnau i kāu kauka e pili ana i kēia)
- ʻO kekahi mau lāʻau antibiotic, no ka laʻana: clarithromycin, erythromycin, telithromycin
- ʻO kekahi mau lāʻau lapaʻau no nā maʻi fungal, no ka laʻana: itraconazole, ketoconazole, voriconazole
- ʻO kekahi mau lāʻau lapaʻau no nā maʻi o ka puʻuwai
- ʻO kekahi mau lāʻau lapaʻau i hoʻohana ʻia e mālama i nā kūlana e like me nā hopu ʻana (fits), no ka laʻana: carbamazepine, phenobarbital, phenytoin
- ʻO kekahi mau lāʻau lapaʻau e pale ai a mālama paha i nā ʻūpā koko, no ka laʻana: warfarin
- ʻO Dextromethorphan
- ʻO Digoxin
- Nefazodone
- Midazolam
- ʻO nā lāʻau lapaʻau ʻē aʻe e hiki ai ke hoʻoulu i kahi ʻano puʻuwai maʻamau, e laʻa me ka hoʻolōʻihi ʻana i ka wā QT , no ka laʻana: dofetilide, ziprasidone
- ʻO Rifabutin
- ʻO Rifampin
- ʻO Rifapentine
- ʻO ka mea hoʻohui lāʻau lapaʻau ʻo St. John's wort (Hypericum perforatum)
- ʻO Tizanidine
ʻAʻole i hoʻokomo ʻia nā pilina āpau ma kēia papa inoa. No laila, e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau (i kauoha ʻia a me nā mea kūʻai ʻole ʻia), nā huahana lāʻau, nā huaora, a me nā mea hoʻohui meaʻai āu e lawe nei. E hōʻoia e haʻi i kāu kauka inā ʻoe e puhipaka, inu waiʻona, a hoʻohana paha i nā lāʻau lapaʻau kū ʻole i ke kānāwai. Hiki i kēia mau mea ke launa pū me kāu lāʻau lapaʻau.
He aha nā mea e pono ai ʻoe e makaʻala nui i ka wā e lawe ai i kēia lāʻau?
He mea nui loa ia e makaʻala mau i kou olakino i ka wā e lawe ana iā Vemurafenib.
- E ʻike pinepine i kāu kauka: E hoʻomau i ka nānā ʻana e like me ka ʻōlelo a kāu kauka iā ʻoe. Pono paha ʻoe e hana i kahi hana koko i ka wā e lawe ana i kēia lāʻau.
- Nā hopena ʻili koʻikoʻi: Hiki i kēia lāʻau lapaʻau ke hana i nā hopena ʻili koʻikoʻi i kekahi manawa. Hiki ke hana ʻia kēia mau mea i nā pule a i ʻole nā mahina ma hope o kou hoʻomaka ʻana e lawe i ka lāʻau lapaʻau. E haʻi koke i kāu kauka inā loaʻa iā ʻoe kahi ʻōhū me nā hōʻailona e like me ke kuni a i ʻole ke anu. Hiki i ka ʻōhū ke lilo i ʻulaʻula a poni paha, a laila pehu a hiki ke hemo ka ʻili. A i ʻole hiki iā ʻoe ke loaʻa kahi ʻōhū ʻulaʻula me ka pehu ʻana o ka maka a i ʻole nā lehelehe, a i ʻole nā kikowaena lymph pehu ma ka ʻāʻī a i ʻole nā armpits. Inā ʻike ʻoe i kekahi mea e like me kēia , e haʻi koke i kāu kauka.
- E kamaʻilio e pili ana i ka pilikia o ka maʻi kanesa: Inā ʻoe e lawe i kēia lāʻau lapaʻau, hiki iā ʻoe ke piʻi aʻe ka pilikia o ka loaʻa ʻana o kekahi mau ʻano maʻi kanesa ʻē aʻe. E kamaʻilio me kāu kauka e pili ana i kēia.
- Nā loli o ka ʻike: Inā ʻike ʻoe i kekahi mau loli i kāu ʻike, e like me ka ʻike maka pōwehiwehi a ʻike paha i nā mea ʻokoʻa ma mua o ka maʻamau, pono ʻoe e haʻi koke i kāu kauka.
- ʻIke i ka lā: He mea nui loa kēia. Ke lawe ʻoe iā Vemurafenib, lilo kou ʻili i mea ʻike nui i ka lā. ʻO ke ʻano kēia, ʻoiai he manawa pōkole i ka lā hiki ke hoʻopau i kou ʻili i ka wela, ʻulaʻula, a pehu.
- No laila, e pale i ka lā i ka hiki.
- Inā pono ʻoe e hele i ka lā,E ʻaʻahu i nā lole e uhi pono i kou ʻili, e ʻaʻahu i ka pāpale ākea, a e hoʻohana i kahi sunscreen maikaʻi i ʻōlelo ʻia e kāu kauka.
- Mai hoʻohana i nā kukui lā a i ʻole nā moena/lumi ʻili.
- Ka hāpai ʻana a me ka hānai ʻana:
- Mai hāpai i ka wā e lawe ana i kēia lāʻau lapaʻau a no 2 mau pule ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau.
- Inā ʻoe e hoʻolālā ana e hāpai a manaʻo paha ʻoe e hāpai ana, e haʻi koke aku i kāu kauka. Hiki i kēia lāʻau lapaʻau ke hōʻeha nui i kahi pēpē i hānau ʻole ʻia. E nīnau i kāu kauka a mea kūʻai lāʻau paha no ka ʻike hou aku.
- Mai hānai i kāu pēpē i ka waiū i ka wā e lawe ana i kēia lāʻau lapaʻau a no 2 mau pule ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau.
He aha nā hopena ʻaoʻao e hiki mai ana?
E like me nā lāʻau lapaʻau āpau, hiki iā Vemurafenib ke hana i kekahi mau hopena ʻaoʻao. He koʻikoʻi kekahi, ʻaʻole koʻikoʻi loa kekahi.
Nā hopena ʻaoʻao e pono e hōʻike koke ʻia i kāu kauka a i ʻole ke kauka olakino:
Inā ʻike ʻoe i kekahi o kēia mau hōʻailona, e haʻi koke aku i kāu kauka:
- Nā hopena maʻi: ka ʻili ʻulaʻula, ka ʻeha a i ʻole ka hives, ka pehu ʻana o ka maka, nā lehelehe a i ʻole ke alelo
- Paʻakikī ka hanu ʻana
- Nā loli o ka ʻike
- Mimi ʻeleʻele
- ʻEha a pehu paha ka maka
- Puʻuwai wikiwiki a ʻano ʻole paha
- Nāwaliwali, poniuniu, a me ka hāʻule ʻana
- ʻO ka malaise laulā a i ʻole nā hōʻailona e like me ke anu
- Nā noho waihoʻoluʻu māmā
- Makemake nui
- ʻIke ʻia kahi wart hou; he ʻeha ʻili a he puʻupuʻu ʻulaʻula paha e kahe ana ke koko a ʻaʻole hoʻi e ho'ōla; he loli i ka nui a i ʻole ke kala o kahi wart a i ʻole kahi kiko
- ʻEha, mae, a nalowale paha ka manaʻo ma nā lālā
- ʻŌhūhū, kuni, a me ka pehu ʻana o nā puʻupuʻu
- ʻUlaʻula ka ʻili, ka pehu ʻana, ka ʻili ʻili (me ka ʻili ʻana i loko o ka waha)
- ʻEha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
- ʻIke i ka lā a i ʻole ka ʻā ʻana o ka lā
- Ka mānoanoa o ka ʻili ma nā poho lima a me nā kapuwaʻi
- Kūlou nā manamana lima i loko a ʻoʻoleʻa
- Manaʻo nāwaliwali a luhi paha
- Ka luaʻi ʻana
- Melemele o nā maka a i ʻole ka ʻili
Nā hopena ʻaoʻao ʻaʻole pono ka mālama lapaʻau (e haʻi i kāu kauka inā hoʻomau kēia mau mea a hoʻopilikia paha):
- Nā loli o ka ʻono
- Ka nalowale o ka makemake
- Ka maʻi ʻōpū (ʻeha ʻōpū)
- Pōʻino
- ʻIli maloʻo
- Pohō lauoho
- ʻEha poʻo
- ʻEha hui
- ʻEha ʻiʻo
- Ka luaʻi (manaʻo maʻi)
- Ka pehu ʻana o nā kuʻekuʻe wāwae, nā wāwae, nā lima
- Luhi
ʻAʻole i hoʻokomo ʻia nā hopena ʻaoʻao āpau i kēia papa inoa. Inā loaʻa iā ʻoe kekahi mau hōʻailona ʻē aʻe, e kūkākūkā me kāu kauka. Inā makemake ʻoe, hiki iā ʻoe ke hōʻike i nā hopena ʻaoʻao i ka FDA (Food and Drug Administration) ma ke kelepona ʻana i ka 1-800-FDA-1088.
Pehea e mālama ai i kēia mau pila?
- E waiho ma kahi hiki ʻole i nā keiki ke kiʻi aku. He mea nui loa kēia.
- E mālama ma ka mahana o ka lumi (ma waena o 20 a me 25 kekelē Celsius / 68 a me 77 kekelē Fahrenheit).
- E mālama i ka lāʻau lapaʻau i loko o ka ʻōmole kumu i hoʻokomo ʻia ai, ua pani paʻa ʻia.
- E hoʻolei i ka lāʻau lapaʻau i pau me ka hoʻohana ʻole ʻana.
ʻO ka mea hope loa, nā mea e pono ai ʻoe e hoʻomanaʻo (Leka Lawe-Home)
He lāʻau lapaʻau ʻo Vemurafenib nona ke kuleana koʻikoʻi i ka mālama ʻana i ka maʻi kanesa. Aia kekahi mau mea āu e makaʻala ai i ka wā e hoʻohana ai.
- E hahai pono i nā kuhikuhi a ke kauka. E hana i nā mea āpau e like me kāna e ʻōlelo ai iā ʻoe, me ka manawa e lawe ai i ka lāʻau lapaʻau, ka nui, a pehea e hoʻōki ai i ka lawe ʻana.
- E haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe ai a me nā maʻi ʻē aʻe āu e loaʻa nei. E kōkua kēia i ka pale ʻana i nā hopena ʻaoʻao.
- Inā ʻike ʻoe i kekahi mau hōʻailona hou, ʻoiai nā loli o ka ʻili a i ʻole nā loli o ka ʻike, e haʻi koke aku i kāu kauka.
- E makaʻala i ka lā. Mai poina i kēia.
- Inā hāpai ʻoe, e hoʻolālā ana e hāpai, a hānai waiū paha, e ʻōlelo pono i kāu kauka ma mua o ka lawe ʻana i kēia lāʻau.
He hōʻuluʻulu manaʻo wale nō kēia ʻatikala. Inā he mau nīnau hou aku kāu e pili ana i kēia lāʻau lapaʻau, mai kānalua e nīnau i kāu kauka, kauka lāʻau, a i ʻole kekahi mea mālama ola kino ʻē aʻe. E hiki iā lākou ke kōkua iā ʻoe.
Makemake mākou iā ʻoe i ka maikaʻi loa i kāu huakaʻi olakino!
ʻO Vemurafenib, Zelboraf, lāʻau lapaʻau maʻi kanesa, maʻi kanesa ʻili, melanoma, nā hopena ʻaoʻao, lāʻau lapaʻau, lāʻau lapaʻau maʻi kanesa
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