Aia kekahi o kou ʻohana, ʻo kou makuahine aloha paha, kou makuakāne, a i ʻole kou hoa ola paha, i loaʻa i ka maʻi Alzheimer? A laila ua ʻike maopopo paha ʻoe i ka paʻakikī a me ka ʻeha no nā mea a pau o ka ʻohana. ʻAʻole maʻalahi ka nānā ʻana i kēia maʻi kahi e nalowale ai kou hoʻomanaʻo i kēlā me kēia lā a poina iā ʻoe ʻo wai ʻoe. No laila, i ka wā e hiki mai ai ka lono e pili ana i kahi lāʻau hou no kēia maʻi, lawe mai ia i ka manaʻolana nui a me nā nīnau he nui i ka noʻonoʻo. "Ke hana maoli nei anei kēia? Aia kekahi mau hopena ʻaoʻao? ʻO wai ka mea hiki ke hoʻohana i kēia?" Pono he nui nā nīnau i loko o kou noʻonoʻo. No laila e kamaʻilio kākou e pili ana i nā mea āpau me ka maopopo a me ka maʻalahi i kēia lā.
He aha kēia lāʻau lapaʻau kamaʻilio hou?
ʻO Lecanemab ka inoa o kēia lāʻau lapaʻau hou, a e kūʻai ʻia aku ia ma lalo o ka inoa ʻo Leqembi. ʻO ka mea mua, ʻo ka mea nui a kākou e pono ai e hoʻomaopopo, ʻaʻole kēia he lāʻau lapaʻau no ka maʻi Alzheimer. Eia naʻe, hana ia i kahi mea nui. ʻO ia hoʻi, hoʻolohi ia i ka holomua o ka maʻi i nā pae mua . I ka ʻōlelo maʻalahi, hoʻolohi ia i ka hōʻino ʻana o ka hoʻomanaʻo a me ka hiki ke noʻonoʻo o ka mea maʻi.
Hāʻawi ʻia kēia ma ke ʻano he infusion intravenous i kēlā me kēia ʻelua pule. Hoʻokomo mālie ʻia ka lāʻau lapaʻau i loko o ke kino, e like me ka saline.
Pehea e hana ai kēia lāʻau lapaʻau?
E noʻonoʻo, ke loaʻa iā kākou ka maʻi Alzheimer, e hōʻiliʻili ana kekahi mea pipili a like me ka ʻōpala ma waena o ko kākou mau hunaola lolo. Kāhea mākou i kēia ʻano amyloid. ʻO kēia protein i kapa ʻia ʻo amyloid ke kumu nui o ka hōʻino ʻana i nā hunaola lolo a me ka nalowale o ka hoʻomanaʻo. No laila, ʻo ka hana a kēia lāʻau hou, ʻo ia ke kuhikuhi ʻana i kēia protein amyloid makemake ʻole ʻia i loko o ka lolo a hoʻopau iā ia. I nā huaʻōlelo ʻē aʻe, hoʻouka kēia lāʻau i ke kumu o ka maʻi.
He ʻanuʻu nui kēia i mua i kā mākou ʻoihana lapaʻau. No ka mea, ʻo ka hapa nui o nā lāʻau lapaʻau i loaʻa no ka manawa lōʻihi ua hiki ke kāohi i kekahi o nā hōʻailona. Akā ke hoʻāʻo nei kēia lāʻau lapaʻau e hoʻololi i ke ala o ka maʻi.
He aha nā hopena a me nā pilikia o kēia?
E like me nā lāʻau lapaʻau āpau, he mau pono a me nā pōʻino kēia. He mea nui e ʻike kākou i nā mea ʻelua.
Ua hōʻike ʻia e ka noiʻi ua loaʻa i nā maʻi i lawe i kēia lāʻau no 18 mau mahina ka emi ʻana o ka hoʻomanaʻo a me ka noʻonoʻo ʻana he 27% i hoʻohālikelike ʻia me ka hui placebo. Ua emi nui ʻia hoʻi ka nui o ka amyloid i loko o ka lolo. ʻOiai ke ʻano he pakeneka liʻiliʻi kēia, he mea nui ia e hiki i kahi maʻi ke ʻike i kā lākou poʻe aloha a hana i kā lākou hana no kekahi mau mahina hou aʻe.
Akā, ua ʻike nō hoʻi mākou i nā pilikia.
ʻO ka pilikia nui o kēia lāʻau lapaʻau he ʻano i kapa ʻia ʻo ARIA (nā ʻano ʻino o ke kiʻi e pili ana i ka amyloid). I ka ʻōlelo maʻalahi, hiki i kēia ke hana i nā pehu liʻiliʻi a i ʻole nā kahe koko liʻiliʻi i loko o ka lolo.Hiki ke hana. Ma ka noiʻi, ua hōʻike ʻia kēia ʻano ma kahi o 14% o ka poʻe i lawe i ka lāʻau. Eia nō naʻe, no ka hapa nui o ka poʻe, ʻaʻole kēia e hōʻike i nā hōʻailona nui. Eia nō naʻe, ʻaʻole hiki ke lilo i mea koʻikoʻi.
He kiʻekiʻe loa kēia pilikia no nā maʻi e lawe ana i nā lāʻau hoʻokahe koko . No laila, he mea nui e haʻi aku ka mea maʻi i ke kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe a lākou e lawe nei ma mua o ka hoʻomaka ʻana i kēia lāʻau.
Eia kekahi, hiki ke loaʻa nā hopena ʻaoʻao e like me ke kuni, ka ʻeha kino, ka nausea, ka luaʻi ʻana, a me nā loli o ke koko i ka wā o ka inikini.
| Nā Pōmaikaʻi | Nā Pōʻino a me nā Pōʻino |
|---|---|
| Hoʻolohi i ka nalowale o ka hoʻomanaʻo i nā wā mua o ka maʻi. | Ka pilikia o ka pehu ʻana o ka lolo a me ke kahe ʻana o ke koko (ARIA). |
| Wehe i nā protein amyloid ʻino mai ka lolo. | Pono e hoʻokomo ʻia i loko o kahi aa i kēlā me kēia ʻelua pule. |
| Lawe mai i ka manaʻolana hou no ka mālama ʻana i ka maʻi. | Pipiʻi loa ke kumukūʻai ma ka honua holoʻokoʻa. |
| Hāʻawi i ka manawa hou aku i ka mea maʻi a me ka ʻohana. | Hiki ke loaʻa nā hopena ʻaoʻao e like me ke kuni a me ka nausea. |
No wai maoli kēia lāʻau lapaʻau?
ʻO kēia ka mea nui loa. ʻAʻole kūpono kēia lāʻau lapaʻau no kēlā me kēia maʻi Alzheimer.
- No nā poʻe maʻi mua wale nō: ʻOi aku ka maikaʻi o kēia lāʻau lapaʻau i nā poʻe maʻi i ke kahua mua o ka maʻi, ʻo ia hoʻi ua hoʻomaka wale lākou e hōʻike i nā hōʻailona. ʻAʻole paha e maikaʻi i nā poʻe maʻi i nā kahua hope o ka maʻi, i ka wā e ʻoi aku ai ka ʻino o ka maʻi.
- Pono e hōʻoia ʻia ʻo Amyloid: Pono e hōʻoia i ka loaʻa ʻana o nā waihona amyloid i loko o ka lolo o ka mea maʻi ma o nā hoʻokolohua kūikawā (kahi PET scan a i ʻole kahi lumbar puncture).
- ʻAʻole no nā ʻano dementia ʻē aʻe: ʻAʻole kūpono kēia lāʻau lapaʻau no nā ʻano nalowale hoʻomanaʻo ʻē aʻe, koe wale nō ʻo Alzheimer's (e.g. vascular dementia).
No laila, hiki i kahi neurologist ke hoʻoholo inā kūpono kēia lāʻau lapaʻau no ka mea maʻi.
Ke kumukūʻai a me ke kūlana ma Sri Lanka
He kiʻekiʻe loa ke kumukūʻai o kēia lāʻau lapaʻau. ʻO ke kumukūʻai makahiki ma ʻAmelika Hui Pū ʻIa ma kahi o $26,500 (ʻoi aku ma mua o 8 miliona kālā Sri Lanka). Hiki ke lōʻihi ka manawa no ka hoʻopaʻa inoa ʻana i kahi lāʻau lapaʻau hou, kūikawā a pipiʻi hoʻi ma ko mākou ʻāina a loaʻa i nā maʻi maʻamau. Eia kekahi, ma muli o ke kumukūʻai kiʻekiʻe, he mea paʻakikī paha i nā mea āpau ke loaʻa.
Eia nō naʻe, he manaʻolana nui kēia no ka wā e hiki mai ana. Me ka holomua o ka ʻepekema, ke manaʻolana nei mākou i kekahi lā, e hoʻomohala hou ʻia kēlā mau lāʻau lapaʻau a e kūpono ke kumukūʻai a loaʻa maʻalahi i nā mea āpau.
Leka Lawe-Home
- ʻAʻole ʻo Lecanemab kahi lāʻau lapaʻau no ka maʻi Alzheimer, akā he lāʻau lapaʻau e hoʻolohi i ka holomua o ka maʻi i nā wā mua .
- Hoʻopau kēia i nā protein amyloid ʻino mai ka lolo, akā he mau hopena ʻino nō hoʻi e like me ka pehu ʻana o ka lolo a me ke kahe ʻana o ke koko.
- ʻAʻole kūpono kēia lāʻau lapaʻau no nā kānaka a pau, ʻoi aku hoʻi no nā poʻe maʻi i nā pae mua o ka maʻi a ua hōʻoia ʻia he amyloid i loko o ka lolo.
- He pipiʻi loa kēia, a ʻaʻole maopopo ka loaʻa ʻana ma Sri Lanka i kēia manawa.
- Inā loaʻa i kekahi o kou ʻohana ka maʻi Alzheimer, e ʻike i kāu kauka e kūkākūkā i nā lāʻau lapaʻau hou a i ʻole nā kūlana olakino. Mai hoʻoholo ma muli o kāu mea e ʻike ai ma ka pūnaewele.
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