Koj puas tau muaj tshuaj no rau koj siv rau kev kho mob ntshav siab? Cia peb kawm txhua yam txog ACE Inhibitors!

Ib qho teeb meem uas ntau tus neeg hauv Sri Lanka muaj yog ntshav siab, lossis "ntshav siab" raws li peb txhua tus paub. Yog li, koj tus kws kho mob yuav tau sau tshuaj rau koj rau koj cov ntshav siab, lossis rau qee yam mob plawv. Ntawm cov hom tshuaj uas tau sau tshuaj, ACE Inhibitors yog ib pawg tshuaj uas siv ntau thiab tseem ceeb heev. Yog tias lub npe ntawm koj cov tshuaj yog ib yam dab tsi zoo li Captopril, Enalapril, Lisinopril, ces koj kuj tseem yuav siv hom tshuaj no. Yog li hnub no, cia peb tham txog cov ACE Inhibitors no yog dab tsi, lawv ua haujlwm li cas hauv peb lub cev, thiab cov yam tseem ceeb tshaj plaws uas peb yuav tsum paub thaum siv lawv yog dab tsi.

Hauv lus yooj yim, cov tshuaj ACE inhibitors no yog dab tsi?

Lub npe tag nrho ntawm qhov no yog Angiotensin - Converting Enzyme Inhibitors. Txawm hais tias lub npe nyuaj me ntsis, nws ua dab tsi yooj yim heev. Yuav kom nkag siab qhov no, cia peb tham txog ib qho txheej txheem me me uas tshwm sim hauv peb lub cev.

Ntau yam tshuaj hormones thiab enzymes ua haujlwm los tswj cov ntshav siab hauv peb lub cev. Ib qho ntawm cov enzymes tseem ceeb hu ua 'ACE (Angiotensin-Converting Enzyme).' Cov enzyme 'ACE' no zoo li lub Hoobkas me me hauv peb lub cev. Lub Hoobkas no hloov cov tshuaj 'Angiotensin I' hauv peb lub cev mus rau hauv lwm yam tshuaj muaj zog hu ua 'Angiotensin II'.

Tam sim no tus txiv neej no hu ua 'Angiotensin II' yog qhov ua haujlwm los ua kom peb cov ntshav siab. Nws ua ob yam tseem ceeb:

1. Cov hlab ntsha nqaim (qhib): Ib yam li thaum cov yeeb nkab dej raug nias, cov dej ntws sai dua, thaum cov hlab ntsha nqaim, qhov chaw rau cov ntshav ntws txo qis, thiab qhov siab hauv cov hlab ntsha nce ntxiv.

2. Txwv tsis pub cov ntsev thiab dej tawm ntawm lub raum: Thaum cov ntsev thiab dej ntau dhau nyob hauv lub cev, cov ntshav yuav nce ntxiv, uas ua rau cov ntshav siab ntxiv.

Tsis yog li ntawd xwb, cov enzyme 'ACE' no rhuav tshem cov protein hu ua 'Bradykinin', uas muaj txiaj ntsig zoo rau peb lub cev thiab ua rau cov hlab ntsha dav dua. Thaum koj noj cov tshuaj ACE inhibitor, vim tias cov enzyme 'ACE' tsis ua haujlwm, ntau cov protein zoo hu ua 'Bradykinin' tseem nyob hauv lub cev.

Hais yooj yim xwb, cov tshuaj ACE inhibitors tiv thaiv kev tsim cov tshuaj uas ua rau ntshav siab thiab tiv thaiv kev poob ntawm cov tshuaj uas txo cov ntshav siab. Qhov kev ua ob yam no pab tswj cov ntshav siab tau zoo heev.

Cov kws kho mob sau cov tshuaj no rau cov xwm txheej twg?

Cov tshuaj ACE Inhibitors tsis yog tsuas yog tshuaj kho mob ntshav siab xwb. Lawv kuj pab tiv thaiv lub plawv thiab lub raum, yog li cov kws kho mob thiaj li sau ntawv rau ntau yam mob.

• Tswj cov ntshav siab:Qhov no yog lub cib fim tseem ceeb tshaj plaws thiab feem ntau siv.
• Kho Mob Plawv Tsis Ua Haujlwm: Thaum lub plawv tsis muaj peev xwm tso ntshav txaus, cov tshuaj no pab txo qhov kev ua haujlwm ntawm lub plawv thiab pab nws ua haujlwm.
• Tom Qab Muaj Mob Plawv Nres: Cov tshuaj no yog muab los pab kom lub plawv rov zoo tom qab muaj mob plawv nres thiab tiv thaiv kev puas tsuaj ntxiv.
• Tiv thaiv cov raum ntawm cov neeg uas muaj ntshav qab zib: Ntshav qab zib tuaj yeem ua rau lub raum puas tsuaj raws sijhawm. Cov tshuaj ACE inhibitors tuaj yeem pab ncua thiab tiv thaiv qhov kev puas tsuaj ntawd.
• Rau cov neeg uas muaj feem yuav mob plawv thiab mob hlwb: Cov no kuj tau sau tseg kom tiv thaiv cov mob no kom tsis txhob tshwm sim rau cov neeg uas muaj feem yuav mob.
• Rau lwm yam kab mob raum: Cov no kuj siv rau qee yam kab mob raum (xws li 'Nephrotic syndrome', 'Proteinuria') uas tshwm sim txawm tias rau cov neeg uas tsis muaj ntshav qab zib.

Cov tshuaj ACE inhibitors twg feem ntau siv?

Muaj ntau hom tshuaj ACE inhibitors nyob rau hauv khw. Koj cov tshuaj yuav muaj ib lub npe teev hauv qab no. Nco ntsoov tias txawm hais tias lub npe generic ntawm cov tshuaj yog tib yam, lub npe hom yuav txawv vim nws yog ua los ntawm ntau lub tuam txhab.

Kuv yuav tsum siv cov tshuaj no li cas?

Feem ntau cov neeg raug sau tshuaj ACE inhibitor ib zaug ib hnub. Txawm li cas los xij, qee tus neeg yuav tsum tau noj nws ob zaug ib hnub. Qhov no yog nyob ntawm koj tus kws kho mob txiav txim siab.

Ib qho tseem ceeb heev yog yuav ua li cas yog tias koj nco qab noj ib koob tshuaj. Xav txog tias koj tsis nco qab noj koj cov tshuaj thaum sawv ntxov. Yog tias koj nco qab thaum nruab hnub, noj nws sai li sai tau thaum koj nco qab. Tab sis yog tias koj nco qab thaum sawv ntxov tom ntej, uas txhais tau tias nws yuav luag txog sijhawm rau koj cov tshuaj tom ntej, tsis txhob noj cov tshuaj uas tsis nco qab. Dhia mus thiab noj cov tshuaj tom ntej raws sijhawm teem tseg. Tsis txhob noj ob lub tshuaj ib zaug, nrog rau qhov koj tsis nco qab. Ua li ntawd tuaj yeem ua rau koj cov ntshav siab poob qis dhau thiab ua rau kiv taub hau.

Cov tshuaj no muaj cov txiaj ntsig thiab cov kev mob tshwm sim li cas?

ACE Inhibitors yog ib pawg tshuaj uas cov kws kho mob thoob ntiaj teb vam khom rau ntau yam laj thawj.

Cov txiaj ntsig tseem ceeb

• Zoo heev: Kev tshawb fawb txog kev tshawb fawb tau ua pov thawj tias cov no zoo heev rau kev tswj cov ntshav siab thiab kab mob plawv.
• Tiv Thaiv Kab Mob: Nws tsis yog tsuas yog kho tus kab mob uas twb muaj lawm xwb, tab sis nws kuj pab tiv thaiv kev mob plawv yav tom ntej, mob hlwb, thiab kab mob raum.
• Sib xws nrog lwm cov tshuaj: Qee zaum cov kws kho mob sau ib lub tshuaj uas muab ACE inhibitor thiab lwm yam tshuaj ntshav siab sib xyaw ua ke.
• Muaj Kev Nyab Xeeb: Cov tshuaj no feem ntau muaj cov kev mob tshwm sim tsawg heev. Cov kev mob tshwm sim loj heev tsis tshua muaj, yog li lawv tuaj yeem siv tau yam tsis muaj kev phom sij rau ib sim neej.

Tej zaum yuav muaj tej yam tshwm sim tsis zoo

Ib yam li lwm yam tshuaj, cov no yuav ua rau muaj kev phiv me me rau qee tus neeg.

Tej yam yuav tsum tau ceev faj thaum siv cov tshuaj no

Cov neeg uas yuav tsum tsis txhob noj cov tshuaj no

• Cov niam cev xeeb tub lossis cov niam uas pub niam mis rau menyuam. (Yog tias koj tab tom yuav muaj menyuam, qhia rau koj tus kws kho mob ua ntej.)
• Cov neeg uas tau muaj mob angioedema (o ntawm lub ntsej muag) ua ntej lawm.
• Cov neeg uas muaj kab mob raum hnyav lossis cov hlab ntsha hauv lub raum stenosis.

Kev sib cuam tshuam nrog lwm cov tshuaj

Yog tias koj noj tshuaj ACE inhibitor, nws yog ib qho tseem ceeb uas yuav tsum qhia rau koj tus kws kho mob txog lwm yam tshuaj uas koj noj (txawm tias cov vitamins).

• Cov Tshuaj Tua Kab Mob (NSAIDs): Yog tias siv cov tshuaj tua kab mob xws li Ibuprofen thiab Diclofenac ntau zaus, lawv tuaj yeem txo qhov ua tau zoo ntawm ACE inhibitors thiab cuam tshuam rau lub raum.
• Cov tshuaj uas cuam tshuam rau cov potassium: Qee cov tshuaj tuaj yeem ua rau cov potassium hauv lub cev nce ntxiv yam tsis tsim nyog (hyperkalemia).
• Ntshav thiab cov khoom siv hloov ntsev: Nrog koj tus kws kho mob tham txog qhov ntau npaum li cas ntsev uas koj yuav tsum noj. Tsis tas li ntawd, nco ntsoov nug koj tus kws kho mob ua ntej siv "cov khoom siv hloov ntsev" uas muaj potassium.

Thaum twg koj yuav tsum nrhiav kev kho mob tam sim ntawd?

Yog tias muaj cov tsos mob hnyav hauv qab no tshwm sim, mus rau Chav Kho Mob Ceev (ETU) ze tshaj plaws tam sim ntawd.

Yog koj noj tshuaj ACE inhibitor, koj tus kws kho mob yuav kom koj kuaj ntshav thiab zis tsawg kawg ib xyoos ib zaug los xyuas koj lub raum ua haujlwm thiab cov ntsev hauv cov ntshav. Nws yog ib qho tseem ceeb heev uas yuav tsum tsis txhob hla cov kev kuaj no.