Koj puas xav tias koj tsis muaj zog thiab kiv taub hau? Tej zaum yuav yog Guillain-Barré Syndrome!

Koj puas xav tias koj lub cev tsis muaj zog lawm, lossis koj ob txhais ceg tsis muaj zog lawm? Tej zaum qhov no yog ib qho cim qhia tias muaj mob hnyav heev. Hnub no peb yuav tham txog ib yam kab mob zoo li no. Nws yog Guillain-Barré Syndrome, lossis luv luv GBS. Txawm hais tias qhov no yog ib yam mob uas tsis tshua muaj, tab sis nws tseem ceeb heev uas yuav tsum paub txog nws.

Guillain-Barré Syndrome yog dab tsi?

Hais yooj yim xwb, Guillain-Barré Syndrome yog ib yam mob tsis tshua muaj uas koj lub cev tiv thaiv kab mob tawm tsam koj lub paj hlwb . Nws ua rau cov hlab ntsha peripheral uas khiav mus rau koj ob txhais ceg thiab lwm qhov ntawm koj lub cev puas tsuaj. Xav txog cov hlab ntsha no zoo li cov xov hlau hauv koj lub cev. Thaum cov hlab ntsha no puas lawm, cov tsos mob xws li loog, tsis muaj zog, thiab txawm tias tuag tes tuag taw tuaj yeem tshwm sim. Tab sis muaj xov xwm zoo. Yog tias kho kom zoo, feem ntau cov neeg tuaj yeem rov zoo los ntawm tus mob no.

Lub npe no kuj txawv me ntsis. Hauv lus Askiv, nws yog hais tias "ghee-AHN buh-RAY".

Leej twg yuav muaj feem mob GBS tshaj?

Kab mob Guillain-Barré tuaj yeem cuam tshuam rau txhua tus neeg txawm tias muaj hnub nyoog li cas los xij. Txawm li cas los xij, nws feem ntau tshwm sim rau cov neeg hnub nyoog ntawm 30 thiab 50 xyoo . Qhov no txhais tau tias cov tub ntxhais hluas thiab cov neeg hnub nyoog nruab nrab kuj muaj feem yuav raug mob.

Qhov no feem ntau tshwm sim li cas?

GBS yog ib yam kab mob uas tsis tshua muaj neeg paub . Muaj li ntawm 7.8 billion tus pej xeem hauv ntiaj teb no, tsuas muaj li ntawm 100,000 tus neeg xwb uas muaj tus kab mob no txhua xyoo. Qhov ntawd txhais tau tias yuav muaj li ntawm ib tug ntawm 78,000 tus neeg uas nyuam qhuav kuaj pom tias muaj tus kab mob no txhua xyoo. Yog li ntawd, qhov no tsis yog ib qho uas pom ntau heev.

Cov tsos mob ntawm GBS yog dab tsi?

Vim tias Guillain-Barré syndrome cuam tshuam rau peb cov hlab ntsha peripheral, nws cuam tshuam rau cov khoom uas cov hlab ntsha ntawd tswj hwm, xws li kev txav ntawm cov leeg, kev hnov ​​​​​​mob, qhov kub thiab txias, thiab kev kov .

Cov tsos mob thawj zaug ntawm GBS yog cov leeg tsis muaj zog thiab/lossis loog (paresthesia) . Cov tsos mob no feem ntau tshwm sim sai sai. Lawv feem ntau cuam tshuam rau ob sab ntawm lub cev sib npaug . Tsis tas li ntawd, nws tuaj yeem pib ntawm ob txhais ceg thiab taw thiab maj mam nthuav mus rau sab saud, mus rau caj npab thiab lub ntsej muag. Thaum cov leeg ntawm ob txhais ceg tsis muaj zog, nws tuaj yeem nyuaj rau taug kev lossis nce ntaiv. Xav txog ib tus neeg uas tau ua haujlwm ib txwm poob ob txhais ceg thiab tsis tuaj yeem taug kev.

Qhov hnyav ntawm GBS yuav txawv ntawm ib tus neeg mus rau ib tus neeg. Ib txhia neeg yuav muaj cov tsos mob me me xwb thiab rov zoo. Lwm tus yuav muaj cov tsos mob hnyav dua. Nyob ntawm seb tus kab mob hnyav npaum li cas, lwm cov tsos mob yuav muaj xws li:

• Mob nqaij nruj nreem rau nraub qaum thiab/lossis ob txhais ceg .
• Mob cov leeg ntawm ob txhais ceg, caj npab, thiab/lossis lub ntsej muag . Thaum mob hnyav, tag nrho lub cev yuav tuag tes tuag taw.
• Cov leeg nqaij hauv siab qaug zog. Qhov no ua rau ua pa nyuaj. Qhov mob no tshwm sim rau kwv yees li ib feem peb ntawm cov neeg uas muaj GBS.
• Nyuaj hais lus thiab nqos (dysphagia) .
• Nyuaj txav lub qhov muag thiab pom kev tsis meej .

Cov tsos mob ntawm GBS tuaj yeem maj mam tshwm sim hauv ob peb teev, ob peb hnub, lossis ob peb lub lis piam . Cov neeg feem coob yuav muaj mob hnyav tshaj plaws hauv ob lub lis piam tom qab cov tsos mob pib. Txog rau lub lis piam thib peb, kwv yees li 90% ntawm cov neeg yuav muaj zog tshaj plaws.

Qhov tseem ceeb tshaj plaws yog, yog tias koj cov leeg nqaij tsis muaj zog thiab nws hnyav zuj zus tuaj li ob peb teev lossis ob peb hnub, mus ntsib kws kho mob tam sim ntawd. Nws yog ib qho tseem ceeb heev uas yuav tsum pib kho tus kab mob GBS sai li sai tau.

Cov teeb meem uas yuav muaj tau ntawm GBS yog dab tsi?

GBS cuam tshuam rau peb lub paj hlwb autonomic, uas tuaj yeem ua rau muaj teeb meem loj heev rau lub neej . Peb lub paj hlwb autonomic tswj cov txheej txheem tseem ceeb uas peb tsis paub tias peb muaj, xws li lub plawv dhia, ntshav siab, thiab kev zom zaub mov. Thaum lub cev no ua haujlwm tsis zoo, nws hu ua dysautonomia.

Qhov dysautonomia uas tshwm sim los ntawm GBS tuaj yeem ua rau muaj teeb meem xws li:

• Cov kab mob plawv dhia tsis xwm yeem.
• Kev tsis ruaj khov ntawm cov ntshav siab.
• Teeb meem zom zaub mov (kev tsis ua haujlwm ntawm txoj hnyuv plab).
• Nyuaj tswj kev tso zis, piv txwv li, kev tso zis tsis tu ncua.

Cov ua rau muaj GBS yog dab tsi?

Guillain-Barré syndrome yog ib qho mob neuropathy tom qab kis kab mob, uas yog los ntawm kev tiv thaiv kab mob . Cia peb piav qhia ntxiv me ntsis:

• Tom Qab Muaj Kab Mob: Feem ntau tus mob no tshwm sim tom qab koj tau muaj kab mob lawm. Kwv yees li 70% ntawm cov neeg uas muaj GBS muaj cov tsos mob hauv ib lub lis piam mus rau rau lub lis piam tom qab muaj kab mob . Cov kws tshawb fawb tseem tsis tau paub meej tias vim li cas qhov no thiaj tshwm sim rau qee tus neeg thiab rau lwm tus tsis tshwm sim.
• Kev tiv thaiv kab mob: Qhov no txhais tau hais tias tus kab mob no yog los ntawm kev teb tsis zoo los ntawm peb lub cev tiv thaiv kab mob. Thaum qee tus neeg mob, lawv lub cev tiv thaiv kab mob teb tsis raug thiab tawm tsam thiab ua puas rau lawv cov hlab ntsha peripheral. Qhov no yog qhov ua rau GBS. Nws kuj yog ib hom mob autoimmune. Txawm li cas los xij, tsis zoo li ntau yam kab mob autoimmune, GBS tsis yog kab mob uas kav ntev mus ib txhis.
• Kab mob hlwb:Kab mob hlwb (Neuropathy) yog ib lo lus dav dav rau cov kab mob uas ua rau cov hlab ntsha puas tsuaj. Hauv GBS, qhov kev puas tsuaj tshwm sim rau cov hlab ntsha sab nraud. Peb lub cev tiv thaiv kab mob sai sai tawm tsam cov hlab ntsha no hauv ib hnub, rhuav tshem cov ntaub thaiv hu ua myelin (zoo ib yam li cov khoom rwb thaiv tsev nyob ib puag ncig cov xov hluav taws xob).

Cov kws tshawb nrhiav tau txheeb xyuas qee yam kab mob thiab lwm yam ua rau lub cev tiv thaiv kab mob uas ua rau GBS. Cov no suav nrog:

• Raws plab los yog kab mob ua pa: Kwv yees li ob feem peb ntawm cov neeg uas muaj GBS raws plab los yog kab mob ua pa ob peb lub lis piam ua ntej cov tsos mob pib. Qhov ua rau GBS tseem ceeb yog kev kis tus kab mob Campylobacter jejuni uas ua rau raws plab.
• Cov kab mob kis: Ib txhia neeg uas muaj GBS kuj tau muaj cov kab mob kis yav dhau los xws li mob khaub thuas, cytomegalovirus, Epstein-Barr virus, thiab Zika virus.
• Tshuaj Tiv Thaiv Kab Mob: Tsis tshua muaj neeg mob GBS ob peb hnub lossis ob peb lub lis piam tom qab tau txais cov tshuaj tiv thaiv kab mob. Tab sis qhov no tseem ceeb heev: Cov txiaj ntsig ntawm kev txhaj tshuaj tiv thaiv kab mob ntau dua li cov kev pheej hmoo. Cov kev tshawb fawb tau qhia tias cov neeg uas tau txais tshuaj tiv thaiv kab mob khaub thuas muaj feem yuav mob GBS ntau dua li cov neeg uas tau txais tshuaj tiv thaiv kab mob khaub thuas.
• Kev Phais Mob: Tsis tshua muaj, GBS tuaj yeem tshwm sim tom qab kev phais mob.

Yuav ua li cas thiaj paub tias "(GBS)" yog dab tsi?

Feem ntau cov kws kho mob kuaj mob Guillain-Barré syndrome raws li koj cov tsos mob thiab keeb kwm kho mob . Koj tus kws kho mob yuav nug koj cov lus nug txog koj cov tsos mob pib li cas thiab thaum twg, thiab yog tias koj tau muaj mob tsis ntev los no. Lawv kuj tseem yuav ua qhov kev kuaj lub cev thiab lub paj hlwb kom paub seb cov leeg nqaij puas tsis muaj zog thiab txo qis lossis tsis muaj cov reflexes tob ntawm cov leeg (hyporeflexia lossis areflexia).

Txawm li cas los xij, muaj ntau lwm yam mob hlwb uas muaj cov tsos mob zoo ib yam li GBS. Yog li ntawd, koj tus kws kho mob yuav hais kom kuaj ntxiv kom paub tseeb tias tsis muaj lwm yam mob. Cov kev kuaj no yuav suav nrog:

• Kev kuaj hluav taws xob Electromyography (EMG) thiab kev kuaj xyuas cov hlab ntsha: Cov kev kuaj no ntsuas kev noj qab haus huv thiab kev ua haujlwm ntawm koj cov leeg nqaij pob txha (cov leeg nqaij txuas rau pob txha) thiab cov hlab ntsha uas tswj lawv.
• Lub qhov ntswg ntawm tus txha nraub qaum / lub duav:Hauv txoj kev kho mob no, koj tus kws kho mob yuav muab ib rab koob ntxig rau hauv koj lub nraub qaum thiab coj ib qho qauv ntawm koj cov kua dej hauv lub hlwb (CSF). Cov qauv no raug xa mus rau chav kuaj mob kom kuaj seb puas muaj cov khoom hauv nws. Hauv kwv yees li 80% ntawm cov neeg uas muaj GBS, cov qe ntshav dawb hauv CSF yog qhov ib txwm muaj, tab sis cov protein ntau dua. Lwm yam kev txawv txav hauv CSF tuaj yeem qhia txog lwm yam mob.
• Kev kuaj duab: Koj tus kws kho mob kuj tseem yuav pom zoo kom kuaj MRI (magnetic resonance imaging) ntawm tus txha nqaj qaum.

Yuav kho tus mob GBS li cas?

Yog koj muaj tus mob Guillain-Barré syndrome, tej zaum koj yuav tau nyob hauv chav kho mob hnyav (ICU) ntawm tsev kho mob kom tau txais kev kho mob. Qhov no yog kom pab pawg kws kho mob tuaj yeem saib xyuas koj kom zoo rau cov teeb meem xws li ua pa nyuaj thiab hloov pauv ntshav siab uas tuaj yeem tshwm sim nrog GBS.

Tsis muaj ib txoj kev kho mob tshwj xeeb rau tus kab mob Guillain-Barré syndrome. Txawm li cas los xij, muaj cov kev kho mob uas tuaj yeem txo qhov hnyav ntawm tus kab mob thiab ua kom lub sijhawm rov zoo sai dua. Muaj ob txoj kev kho mob tseem ceeb rau GBS:

• Kev pauv plasma (plasmapheresis): Hauv kev kho mob no, lub tshuab cais cov plasma ntawm koj cov ntshav, kho nws, thiab tom qab ntawd xa cov plasma thiab cov ntshav rov qab rau koj lub cev. Kev pauv plasma lim cov tshuaj tua kab mob uas tawm tsam koj cov hlab ntsha ntawm koj cov plasma.
• Kev kho mob immunoglobulin hauv cov hlab ntsha (IVIG): Hauv kev kho mob no, cov protein hu ua immunoglobulins, uas tau sau los ntawm cov ntshav ntawm ntau txhiab tus neeg noj qab haus huv, raug muab rau hauv cov hlab ntsha (rau hauv cov hlab ntsha). Cov immunoglobulins no yog cov protein uas peb lub cev tiv thaiv kab mob tsim tawm los tawm tsam cov kab mob txawv teb chaws. IVIG tuaj yeem txo lub sijhawm uas koj lub cev tiv thaiv kab mob tawm tsam koj cov hlab ntsha.

Yog tias koj pib kho ob yam no ua ntej ob lub lis piam tom qab koj pib muaj cov tsos mob GBS, ces lub sij hawm rov zoo yuav luv dua.

Kev kho mob rau cov teeb meem

Thaum GBS cuam tshuam rau koj lub paj hlwb autonomic thiab ua rau koj lub cev tsis muaj zog kiag li, tej zaum yuav muaj teeb meem tshwm sim. Koj pab neeg kho mob yuav saib xyuas koj txoj kev ua pa, koj lub plawv dhia, thiab koj cov ntshav siab. Lawv yuav ua haujlwm sai sai yog tias muaj teeb meem tshwm sim. Qee qhov piv txwv ntawm kev kho mob rau cov teeb meem suav nrog:

• Kev saib xyuas kev ua pa: Yog tias GBS cuam tshuam rau koj cov leeg ua pa, koj yuav xav tau kev pab ua pa los ntawm tshuab. Kwv yees li 30% ntawm cov neeg uas muaj GBS ua pa nyuaj.
• Tiv thaiv cov ntshav txhaws:Thaum koj tsis nco qab kiag li thiab pw hauv tsev kho mob ntev heev, koj tus kws kho mob yuav muab tshuaj rau koj xws li heparin (tshuaj tiv thaiv kev coagulation) kom tiv thaiv cov ntshav txhaws hauv koj cov leeg ntshav tob (deep vein thrombosis).
• Cov kua dej hauv cov hlab ntsha thiab cov raj pub mis: Yog tias nqos nyuaj, tej zaum yuav xav tau cov kua dej hauv cov hlab ntsha kom tiv thaiv kev qhuav dej thiab pub mis los ntawm cov raj nasogastric kom tiv thaiv kev tsis noj qab haus huv. Qhov no kuj tseem tuaj yeem pab tiv thaiv cov khoom noj lossis cov kua dej kom tsis txhob nkag mus rau hauv cov hlab ntsha thiab ua rau muaj mob ntsws los ntawm kev nqus pa.

Kev kho dua tshiab

Thaum koj tus mob zoo dua, koj pab neeg kho mob yuav xa koj mus rau qhov chaw kho kom rov zoo. Nyob ntawd, koj tuaj yeem ua haujlwm nrog cov kws kho lub cev thiab lwm tus kws kho mob kom rov qab muaj zog thiab pib ua kom koj lub cev rov qab muaj zog los pab koj rov qab ua koj cov dej num txhua hnub. Cov kev kho mob no yuav suav nrog:

• Kev Kho Mob Lub Cev: Qhov no pab txhim kho txoj kev uas koj lub cev txav mus los. Tus kws kho mob lub cev tuaj yeem pab koj tswj cov tsos mob xws li mob, mob nqaij, thiab tsis xis nyob. Lawv kuj tseem tuaj yeem pab koj ua cov kev tawm dag zog kom rov qab tau cov leeg nqaij.
• Kev Kho Mob Ua Haujlwm: Kev kho mob no maj mam pab koj txhim kho koj lub peev xwm ua haujlwm txhua hnub. Tus kws kho mob ua haujlwm qhia koj yuav ua li cas sawv, zaum, txav mus los, lossis siv ntau yam khoom siv los ua koj txoj haujlwm kom muaj kev nyab xeeb.
• Kev Kho Mob Hais Lus: Yog tias GBS tau cuam tshuam rau cov leeg nqaij hauv koj lub qhov ncauj lossis caj pas, tus kws kho mob hais lus tuaj yeem pab koj rov qab tau koj lub peev xwm nqos thiab hais lus.
• Cov khoom siv pab txhawb kev txav mus los: Cov khoom siv xws li pas nrig, cov hlau txhawb nqa, cov khoom siv taug kev, thiab lub rooj zaum muaj log tuaj yeem pab txhim kho koj txoj kev txav mus los thiab tiv thaiv kev ntog. Lawv kuj tseem tuaj yeem pab txo qhov qaug zog.

Puas tiv thaiv tau GBS?

Feem ntau, Guillain-Barré syndrome tsis tuaj yeem tiv thaiv tau. Cov kws tshawb fawb tseem tsis tau paub tias vim li cas qee tus neeg thiaj li muaj GBS tom qab mob thiab lwm tus tsis paub. Txawm li cas los xij, ib yam uas koj ua tau los txo koj txoj kev pheej hmoo ntawm kev mob GBS yog kom noj qab haus huv li sai tau. Cov kauj ruam no tuaj yeem pab tau:

• Ntxuav koj txhais tes ntau zaus.
• Nyob deb ntawm cov neeg uas muaj mob plab lossis lwm yam kab mob.
• Ua kom koj lub cev tiv thaiv kab mob muaj zog los ntawm kev noj zaub mov zoo thiab tawm dag zog tsis tu ncua.
• Khaws cov chaw uas neeg feem ntau kov xws li cov rooj, cov khoom ua si, cov qhov rooj, xov tooj, thiab cov khoom siv hauv chav dej kom huv si thiab tua kab mob.
• Tau txais tag nrho koj cov tshuaj tiv thaiv kab mob raws sijhawm.

Yuav ua li cas thiaj paub tias tus neeg uas muaj GBS yuav muaj mob li cas?

Qhov kev kwv yees rau ib tus neeg uas muaj tus kab mob Guillain-Barré syndrome yuav txawv. Feem ntau cov neeg uas muaj GBS yuav zoo rov qab los hauv ob peb lub hlis. Txawm li cas los xij, kwv yees li 30% ntawm cov neeg laus - thiab ntau dua cov menyuam yaus - tseem yuav muaj qee qhov tsis muaj zog ntawm cov leeg nqaij peb xyoos tom qab kuaj pom.

Puas kho tau Guillain-Barré syndrome tag nrho?

Feem ntau, cov tsos mob ntawm Guillain-Barré syndrome yuav zoo dua qub nrog lub sijhawm thiab kev kho mob. Cov neeg feem coob pib zoo li qub hauv ob mus rau peb lub lis piam tom qab pib muaj cov tsos mob. Lub sijhawm uas nws siv los kho kom zoo tag nrho tuaj yeem yog txij li ob peb lub hlis mus rau ib xyoos lossis ntau dua, nyob ntawm qhov hnyav ntawm tus mob.

Guillain-Barré syndrome thiab lub neej

Cov neeg uas rov zoo los ntawm tus kab mob Guillain-Barré syndrome muaj lub neej ntev li qub. Muaj tsawg dua 2% ntawm cov neeg tuag los ntawm GBS thaum lub sijhawm mob hnyav. Cov laj thawj tseem ceeb ntawm kev tuag uas cuam tshuam nrog GBS suav nrog:

• Mob ntsws o.
• Sepsis (kev lom ntshav).
• Mob ua pa nyuaj heev (ARDS).
• Cov ntshav txhaws hauv lub ntsws (pulmonary embolism).
• Lub plawv nres.

Yog tias kuv muaj GBS, kuv yuav saib xyuas kuv tus kheej li cas?

Cov txheej txheem kho mob los ntawm Guillain-Barré syndrome tuaj yeem qeeb rau qee tus neeg. Tsis txhob yig nrhiav kev txhawb nqa lub cev thiab lub siab los ntawm koj cov neeg hlub. Koj pab neeg kho mob yeej npaj txhij pab koj.

Kev poob siab lossis kev tsis taus uas tsis tau xav txog tam sim ntawd tuaj yeem ua rau koj ntxhov siab heev. Yog tias koj xav tias koj ntxhov siab txog GBS, nrog ib tus kws kho mob hlwb tham, xws li tus kws kho mob hlwb tham. Ib pawg neeg txhawb nqa kuj tseem tuaj yeem pab koj sib txuas lus nrog lwm tus uas muaj kev paub thiab kev xav zoo sib xws.

Guillain-Barré syndrome (GBS) yog ib yam mob hnyav uas tuaj yeem hloov koj txoj kev noj qab haus huv tam sim ntawd. Qhov xov xwm zoo yog tias feem ntau cov neeg uas muaj GBS yuav zoo rov qab zoo nrog kev kho mob. Txawm li cas los xij, nws yuav siv sijhawm. Cov txheej txheem rov zoo tuaj yeem nyuaj thiab nkees. Nco ntsoov, koj pab neeg kho mob nrog koj txhua kauj ruam ntawm txoj kev. Thiab tsis txhob hnov ​​​​qab nrhiav kev txhawb nqa los ntawm koj cov neeg hlub.

Cia peb nco ntsoov tej yam tseem ceeb tshaj plaws (Cov Lus Coj Mus Tsev)

• Guillain-Barré Syndrome yog ib yam kab mob tsis tshua muaj uas peb lub cev tiv thaiv kab mob tawm tsam peb cov hlab ntsha.
• Qhov no feem ntau tshwm sim tom qab muaj kev kis kab mob xws li kub taub hau, mob khaub thuas, lossis raws plab.
• Cov tsos mob tseem ceeb yog cov leeg nqaij tsis muaj zog thiab loog uas pib ntawm ob txhais ceg thiab kis mus rau lub cev sab saud.
• Kuj tseem yuav muaj teeb meem ua pa nyuaj, nqos nyuaj, thiab cov leeg nqaij ntawm lub ntsej muag tsis ua haujlwm zoo.
• Yog koj muaj cov tsos mob no, mus ntsib kws kho mob tam sim ntawd.Kev kho mob sai yog qhov tseem ceeb heev.
• Cov kev kho mob xws li plasmapheresis thiab IVIG tuaj yeem tswj tau tus kab mob thiab ua kom rov zoo sai dua.
• Nws yuav siv sijhawm me ntsis kom rov zoo, thiab nws yuav xav tau kev kho mob xws li kev kho lub cev.
• Txawm hais tias feem ntau cov neeg zoo tag nrho los xij, qee tus tseem yuav muaj qee qhov tsis muaj zog.
• Txawm hais tias qhov no nyuaj rau tiv thaiv los xij, koj tuaj yeem txo koj qhov kev pheej hmoo los ntawm kev noj qab haus huv.

Yog koj muaj lus nug ntxiv txog qhov no, tsis txhob yig nug koj tus kws kho mob. Nyob kom noj qab nyob zoo!

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