Puas muaj tej lub sij hawm koj xav tias koj nkees heev, koj cov pob qij txha mob, thiab koj cov ntiv tes o? Muaj tej hnub koj daim tawv nqaij tawm pob, thiab muaj tej hnub koj ua tsis taus pa me ntsis. Cov tsos mob no zoo ib yam li lwm yam kab mob, yog li koj yuav xav tias, "Kuv muaj teeb meem dab tsi?" Tej zaum koj yuav tsis paub tseeb tias qhov no yog ib yam kab mob lossis kev sib xyaw ua ke ntawm ntau yam kab mob. Hnub no peb yuav tham txog ib yam mob uas ua rau muaj ntau yam tsos mob no ua ke, uas nyuaj me ntsis, tab sis nws tseem ceeb heev uas yuav tsum paub txog. Qhov no hu ua Kab Mob Sib Xyaws Sib Txuas (MCTD).
Hais yooj yim xwb, MCTD yog dab tsi?
MCTD yog ib qho kab mob autoimmune uas tsis tshua muaj. Zoo, yog li ntawd, kab mob autoimmune yog dab tsi? Hais yooj yim, peb muaj lub cev tiv thaiv kab mob hauv peb lub cev. Nws zoo li ib pab tub rog hauv peb lub tebchaws. Nws txoj haujlwm yog lees paub thiab tawm tsam cov yeeb ncuab xws li cov kab mob, cov kab mob, thiab cov kab mob uas nkag mus rau hauv lub cev thiab tiv thaiv peb ntawm kab mob. Tab sis qee zaum, peb tus kheej txoj kev tiv thaiv mus tsis zoo. Hloov chaw ntawm cov yeeb ncuab txawv teb chaws, lawv yuam kev peb cov nqaij thiab cov hlwb noj qab haus huv rau "cov yeeb ncuab" thiab pib tawm tsam lawv. Qhov ntawd yog qhov peb hu ua kab mob autoimmune.
Qhov tshwm sim hauv MCTD yog tias cov tsos mob ntawm peb yam kab mob tseem ceeb ntawm cov nqaij sib txuas ua ke. Yog vim li ntawd nws thiaj hu ua "sib xyaw." Peb yam kab mob no yog:
- Kab mob lupus erythematosus (SLE): Qhov no yog tus kab mob uas peb feem ntau hu ua "lupus" luv.
- Scleroderma: Qhov no feem ntau yog tus cwj pwm los ntawm kev tuab thiab tawv ntawm daim tawv nqaij.
- Polymyositis: Qhov no ua rau cov leeg tsis muaj zog thiab o.
Ntxiv rau peb yam kab mob tseem ceeb no, qee tus neeg kuj tseem yuav muaj cov tsos mob ntawm lwm yam kab mob ntawm cov nqaij sib txuas, xws li dermatomyositis , rheumatoid arthritis , lossis Sjögren's syndrome . Yog vim li ntawd cov kws kho mob thiaj hu qhov mob no ua "Overlap Syndrome," lossis ib qho mob uas ntau yam kab mob sib tshooj.
Cov tsos mob ntawm MCTD yog dab tsi?
Ib qho teeb meem loj tshaj plaws nrog qhov no yog tias cov tsos mob tsis tshwm sim tag nrho ib zaug. Lawv tuaj yeem tshwm sim dhau sijhawm, ib qho tom qab lwm qhov. Yog li nws tuaj yeem nyuaj me ntsis los paub nws yog MCTD thaum ntxov. Cia peb saib cov tsos mob tseem ceeb uas koj yuav pom.
| Cov tsos mob | Piav qhia yooj yim |
|---|---|
| Xav tias nkees heev thiab tsis muaj sia nyob | Txawm tias tsis tau ua dab tsi los xij, koj yuav xav pw hauv txaj tas hnub. |
| Kub taub hau qis | Txawm tias koj tsis kub taub hau heev los, koj xav tias koj tau txais cua sov los ntawm sab hauv koj lub cev, thiab koj lub cev mob. |
| Mob pob qij txha thiab mob nqaij | Cov pob qij txha mob thiab o tsis muaj laj thawj tshwj xeeb. Cov leeg nqaij qaug zog thiab mob. |
| Qhov tshwm sim ntawm Raynaud | Thaum raug cua txias (piv txwv li, nyob hauv chav AC, coj ib yam dab tsi tawm hauv lub tub yees), cov ntshav ntws mus rau cov ntiv tes, cov ntiv taw, qhov ntswg, thiab pob ntseg txo qis, ua rau lawv daj ntseg, tsis muaj sia, thiab tom qab ntawd tig xiav/ntshav. Thaum sov dua, lawv tig liab thiab rov qab mus rau qhov qub. |
| Cov ntiv tes o | Cov ntiv tes zoo li cov hnyuv ntxwm thiab o. Qee zaum qhov no ploj mus tom qab ob peb hnub. Txawm li cas los xij, rau qee tus neeg, dhau sijhawm, daim tawv nqaij ntawm cov ntiv tes yuav tawv, nyias, thiab nyuaj rau khoov (sclerodactyly). |
| Cov tawv nqaij ua pob khaus | Tej zaum yuav muaj cov pob liab los yog xim av liab los yog cov thaj ua rau thaj, tshwj xeeb tshaj yog rau ntawm cov pob qij txha. |
MCTD xav li cas thaum muaj mob hnyav zuj zus?
Ib tug neeg uas muaj MCTD tsis tas li xav tias zoo li qub. Qee zaum cov tsos mob yuav ploj mus thiab zoo li qub. Tab sis lwm lub sijhawm tus kab mob tam sim ntawd hnyav zuj zus. Peb hu qhov no ua 'kev kub ntxhov'. Thaum lub sijhawm no, koj cov tsos mob yuav hnyav zuj zus me ntsis.
- Tej zaum yuav muaj mob hnyav thiab o ntawm cov pob qij txha. Ib yam li ib tug neeg uas muaj mob pob qij txha rheumatoid, cov pob qij txha yuav mob heev uas lawv tsis tuaj yeem khoov lawv cov ntiv tes thaum sawv ntxov.
- Kab mob Raynaud no muaj peev xwm ua rau mob hnyav heev. Txawm tias mob khaub thuas me ntsis los kuj ua rau cov ntiv tes loog, tsis muaj sia, thiab hloov xim.
- Tej zaum koj yuav xav tias nkees heev , zoo li koj tau kub taub hau tau ntau hnub lawm, mob cov leeg nqaij thiab xav tias tsis muaj zog ua dab tsi li.
Dab tsi ua rau MCTD? Leej twg muaj feem yuav mob tshaj?
Qhov tseeb, cov kws tshawb nrhiav tseem tsis tau pom qhov ua rau muaj MCTD. Nws tsis yog ib yam kab mob uas kis tau ncaj qha los ntawm niam txiv mus rau cov menyuam, uas txhais tau tias nws yog los ntawm noob caj noob ces. Txawm li cas los xij, nws tau pom tias yog tias ib tug neeg hauv tsev neeg muaj lwm yam kab mob ntawm cov nqaij sib txuas, lwm tus kuj yuav muaj feem ntau dua los mob no.
Sib nrug ntawm qhov ntawd, kuv xav tias qee yam sab nraud kuj tseem yuav cuam tshuam qhov no.
- Qee cov kab mob viral .
- Kev raug rau qee yam tshuaj lom neeg , xws li polyvinyl chloride thiab silica.
Txawm hais tias tus kab mob no tuaj yeem tshwm sim thaum twg los tau, feem ntau pom muaj rau cov poj niam hnub nyoog ntawm 20 thiab 30 xyoo .
Muaj teeb meem dab tsi tshwm sim vim yog MCTD?
MCTD tsis yog ib yam kab mob sib koom ua ke xwb. Yog tias tsis kho, nws tuaj yeem ua rau cov kab mob tseem ceeb puas tsuaj thiab ua rau muaj teeb meem loj heev. Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav tsum paub txog qhov no.
Nco ntsoov tias, tsis yog txhua yam teeb meem no yuav tshwm sim rau txhua tus neeg mob, tab sis nws yog ib qho tseem ceeb kom paub txog cov kev pheej hmoo.
Cov teeb meem tseem ceeb uas tuaj yeem tshwm sim yog:
- Mob ntshav siab hauv lub ntsws: Qhov no yog qhov teeb meem txaus ntshai tshaj plaws ntawm MCTD. Hais yooj yim xwb, nws yog kev nce siab ntawm cov hlab ntsha uas nqa ntshav los ntawm lub plawv mus rau lub ntsws. Qhov no ua rau lub plawv ntxhov siab heev thiab tuaj yeem ua rau muaj mob hnyav xws li lub plawv tsis ua haujlwm. Qhov mob no yog qhov ua rau tuag ntau tshaj plaws hauv cov neeg mob MCTD.
- Kab mob ntsws interstitial: o thiab caws pliav ntawm cov nqaij ntsws, uas tuaj yeem ua rau ua pa nyuaj.
- Kab mob plawv
- Kev puas tsuaj rau lub raum
- Kev puas tsuaj rau txoj hnyuv zom zaub mov
- Kab mob ntshav tsis txaus
- Kev tuag ntawm cov ntaub so ntswg (necrosis)
- Kev hnov lus tsis zoo
Cov kws kho mob kuaj mob no li cas thiaj paub tseeb?
Raws li peb tau tham ua ntej lawm, cov tsos mob ntawm MCTD tuaj yeem tshwm sim ib qho tom qab ib qho dhau ib qho dhau sijhawm, ua rau nws nyuaj rau cov kws kho mob kuaj mob. Nws tuaj yeem siv sijhawm ntau xyoo los paub tseeb tias nws yog MCTD. Muaj ib tus kws kho mob uas tshwj xeeb hauv cov mob no, hu ua tus kws kho mob rheumatologist . Yog tias koj muaj cov tsos mob no, koj tus kws kho mob yuav xa koj mus rau ib tus kws tshwj xeeb no.
Muaj plaub yam tseem ceeb uas pab qhia qhov txawv ntawm MCTD los ntawm lwm cov kab mob sib txuas:
1. Muaj cov tshuaj antibody hu ua anti-U1-RNP ntau hauv cov ntshav: Qhov no tuaj yeem kuaj pom nrog kev kuaj ntshav tshwj xeeb. Cov tshuaj antibody no yog tshwj xeeb rau cov neeg mob MCTD.
2. Tsis muaj teeb meem loj raum thiab lub paj hlwb: Cov teeb meem no feem ntau tshwm sim hauv lupus (SLE). Txawm li cas los xij, lawv tsis tshua muaj nyob hauv MCTD.
3. Muaj mob pob qij txha hnyav thiab mob ntshav siab hauv lub ntsws: Cov tsos mob no feem ntau tshwm sim hauv MCTD dua li hauv lupus lossis scleroderma nkaus xwb.
4. Qhov teeb meem Raynaud thiab ntiv tes o: Txawm hais tias tsuas yog 25% ntawm cov neeg mob lupus muaj cov tsos mob no, lawv feem ntau tshwm sim ntawm cov neeg mob MCTD.
Cov kev kho mob rau MCTD yog dab tsi?
Ua ntej tshaj plaws, tsis muaj kev kho rau MCTD. Tab sis tsis txhob txhawj. Muaj ntau txoj kev kho mob zoo uas tuaj yeem pab koj tswj koj cov tsos mob, tiv thaiv cov teeb meem, thiab ua neej nyob li qub. Kev kho mob nyob ntawm seb koj cov tsos mob zoo li cas, qhov hnyav ntawm koj tus mob, thiab cov kab mob uas raug cuam tshuam.
| Hom tshuaj | Kev Ua Haujlwm thiab Kev Siv |
|---|---|
| Cov tshuaj Corticosteroids Piv txwv li: prednisone | Cov no ua haujlwm los ntawm kev txo qhov mob hauv lub cev thiab tswj qhov ua haujlwm ntawm lub cev tiv thaiv kab mob. Lawv tuaj yeem muab cov tshuaj tsawg dua yog tias tus kab mob tsis hnyav, thiab muab cov tshuaj ntau dua yog tias nws hnyav. |
| Cov tshuaj tiv thaiv kab mob malaria Piv txwv li: hydroxychloroquine | Cov no pab tiv thaiv kom tsis txhob muaj mob hnyav zuj zus thiab tswj tau cov tsos mob me me. |
| Cov tshuaj calcium channel blockers | Cov no pab tswj Raynaud tus kab mob los ntawm kev so cov leeg ntawm cov phab ntsa ntawm cov hlab ntsha, ua rau cov ntshav ntws tau yooj yim dua. |
| Lwm cov tshuaj tiv thaiv kab mob | Yog tias cov kabmob tseem ceeb xws li lub ntsws thiab lub raum tau raug puas tsuaj lawm, tej zaum yuav tsum tau muab cov tshuaj muaj zog zoo li no los tswj kev ua haujlwm ntawm lub cev tiv thaiv kab mob. |
| Cov tshuaj tiv thaiv ntshav siab | Cov no yog qhov tseem ceeb los tswj kev ntshav siab hauv lub ntsws. |
Koj yuav saib xyuas koj tus kheej li cas?
Ntxiv rau kev noj cov tshuaj uas koj tus kws kho mob sau ntawv, kev hloov me me rau koj txoj kev ua neej tuaj yeem ua rau kev nyob nrog tus kab mob no yooj yim dua.
- Siv cov tshuaj tua mob: Yog tias mob me ntsis thiab o, koj tuaj yeem tham nrog koj tus kws kho mob txog kev noj cov tshuaj tsis-steroidal anti-inflammatory (NSAIDs) - xws li ibuprofen - piv txwv li. Tab sis tsis txhob siv cov no tas li yam tsis tau sab laj nrog kws kho mob .
- Tiv thaiv koj txhais tes kom tsis txhob mob khaub thuas: Qhov no tseem ceeb heev yog tias koj muaj tus kab mob Raynaud. Hnav hnab looj tes thaum hnub txias. Khaws koj txhais tes kom sov thaum nyob hauv chav txias. Ceev faj thaum coj cov khoom tawm ntawm lub tub yees.
- Tsis txhob haus luam yeeb kiag li: Kev haus luam yeeb ua rau cov hlab ntsha nqaim ntxiv, uas tuaj yeem ua rau Raynaud tus mob hnyav dua.
- Txo kev ntxhov siab: Kev ntxhov siab yog ib qho ua rau muaj tus kab mob Raynaud's. Yog li ntawd, sim ua kom koj lub siab tus los ntawm kev ua tej yam xws li kev ua pa thiab kev xav. Yog tias tsim nyog, nws tseem yog ib lub tswv yim zoo los nrhiav kev pab los ntawm tus kws pab tswv yim txog kev noj qab haus huv ntawm lub hlwb.
Nyob nrog MCTD ntev heev
Vim tias MCTD yog ib qho mob ntev, nws yog ib qho tseem ceeb uas yuav tsum kawm kom paub nyob nrog nws. Tshwj xeeb tshaj yog thaum noj cov tshuaj xws li corticosteroids ntev, tuaj yeem muaj qee qhov kev phiv.
- Kev qaug zog ntawm cov pob txha vim yog osteoporosis.
- Kev tuag ntawm cov nqaij vim yog cov ntshav tsis txaus rau cov nqaij.
- Cov leeg tsis muaj zog.
- Yooj yim raug kab mob.
Koj yuav tsum mus ntsib koj tus kws kho mob raws sijhawm teem tseg kom tswj thiab saib xyuas cov kev mob tshwm sim no. Ua raws li tus kws kho mob cov lus qhia kom meej.
Yog tias ib tug poj niam uas muaj MCTD tab tom npaj yuav muaj menyuam, nws yog ib qho tseem ceeb uas yuav tsum nrog nws tus kws kho mob tham ua ntej . Qhov mob no tuaj yeem hnyav zuj zus thaum cev xeeb tub. Tsis tas li ntawd, cov menyuam mos uas yug los ntawm cov niam uas muaj MCTD yuav muaj qhov hnyav tsawg thaum yug los.
Kuv yuav tsum mus ntsib kws kho mob thaum twg?
Yog koj muaj ib qho tsos mob uas tau hais hauv tsab xov xwm no, tshwj xeeb yog tias lawv cuam tshuam rau koj cov dej num txhua hnub, koj yuav tsum mus ntsib kws kho mob. Yog tias koj muaj mob pob qij txha lossis mob nqaij, o ntawm koj cov ntiv tes, lossis muaj cov cim qhia txog 'Raynaud's phenomenon', nrhiav kev pab kho mob.
Thaum koj mus ntsib kws kho mob, koj tuaj yeem nug cov lus nug no:
- Ua rau kuv cov tsos mob yog dab tsi?
- Kuv puas muaj ntau tshaj ib yam kab mob ntawm cov nqaij sib txuas?
- Kuv yuav tsum tau ua cov kev ntsuam xyuas twg?
- Cov kev kho mob rau kuv tus mob yog dab tsi?
- Kuv yuav ua li cas thiaj li tiv thaiv tau tus kab mob kom tsis txhob loj zuj zus?
Nyob nrog tus kab mob no, tej zaum koj yuav xav tsis thoob tias koj lub neej yuav zoo li cas hauv 10 xyoo. Cov ntaub ntawv qhia tau tias nrog kev kho mob kom zoo, kwv yees li 80% ntawm cov neeg mob tuaj yeem nyob tsawg kawg 10 xyoo tom qab kuaj pom. Tab sis tsuas yog koj tus kws kho mob tuaj yeem muab cov ntaub ntawv zoo tshaj plaws thiab raug tshaj plaws rau koj txog qhov no. Vim tias nws nyob ntawm ntau yam, xws li qhov xwm txheej ntawm koj tus kab mob thiab cov kabmob cuam tshuam.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- MCTD yog ib yam kab mob autoimmune nyuaj uas muaj cov tsos mob ntawm ntau lwm yam kab mob, xws li lupus, scleroderma, thiab polymyositis.
- Tej zaum yuav muaj cov tsos mob uas zoo li tsis muaj feem cuam tshuam, xws li mob pob qij txha, qaug zog heev, o ntawm cov ntiv tes, thiab cov ntiv tes hloov xim thaum huab cua txias (Raynaud's).
- Txawm hais tias tus kab mob no tsis tuaj yeem kho tau tag nrho los xij, muaj cov kev kho mob zoo uas tuaj yeem tswj cov tsos mob, tiv thaiv cov teeb meem, thiab cia koj ua neej nyob li qub.
- Nws yog ib qho tseem ceeb uas yuav tsum nrhiav kev pab los ntawm ib tus kws tshwj xeeb, xws li kws kho mob rheumatologist, rau kev kuaj mob thiab kev kho mob.
- Mus ntsib kws kho mob raws sijhawm, tsis txhob haus luam yeeb, tiv thaiv koj tus kheej kom tsis txhob mob khaub thuas, thiab tswj kev ntxhov siab yog qhov tseem ceeb rau kev tswj kab mob.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus