Koj puas muaj cov protein tiv thaiv kab mob ntau dhau hauv koj lub cev? Cia peb kawm txog Polyclonal Gammopathy hauv cov lus yooj yim!

Puas tau muaj ib tug kws kho mob qhia rau koj tias koj muaj cov protein tiv thaiv kab mob (immunoglobulins) ntau dhau hauv koj cov ntshav? Nws yog ib qho ib txwm muaj uas koj yuav ntshai me ntsis thaum koj hnov ​​​​​​ib yam dab tsi zoo li ntawd. Tab sis tsis txhob txhawj. Hnub no peb yuav tham txog ib qho mob hu ua "Polyclonal Gammopathy." Peb yuav piav qhia txog nws yog dab tsi, vim li cas nws tshwm sim, thiab koj tuaj yeem ua dab tsi txog nws hauv txoj kev yooj yim, yooj yim to taub.

Qhov Polyclonal Gammopathy no yog dab tsi?

Hais yooj yim xwb, polyclonal gammopathy yog ib qho mob uas qee cov hlwb tiv thaiv kab mob hauv koj cov ntshav tsim ntau cov tshuaj tiv thaiv kab mob , lossis immunoglobulins, ib hom protein uas pab peb lub cev tiv thaiv lawv tus kheej ntawm kab mob. Xav txog cov tshuaj tiv thaiv kab mob no ua cov tub rog tiv thaiv lub cev. Lawv yog cov uas tawm tsam kab mob thiab cov kab mob thaum lawv los txog.

Yog li, lo lus "polyclonal" txhais tau hais tias ntau hom hlwb tiv thaiv kab mob sib txawv los ua ke thiab tsim ntau hom tshuaj tiv thaiv kab mob sib txawv. Nws zoo li cov pab pawg sib txawv ua haujlwm ua ke, tsis yog tib hom tub rog xwb.

Vim li cas qhov no thiaj tshwm sim? Qhov no cuam tshuam li cas rau kuv?

Yog tias koj muaj polyclonal gammopathy, nws txhais tau tias koj lub cev tiv thaiv kab mob ua haujlwm ntau dhau . Zoo li nws ib txwm ceeb toom. Qhov laj thawj tseem ceeb rau qhov no yog tias koj lub cev tiv thaiv kab mob tau txais cov cim los ntawm kev kis kab mob lossis kab mob autoimmune, qhia nws kom "ua cov tshuaj tiv thaiv, ua cov tshuaj tiv thaiv."

Uas yog, polyclonal gammopathy tuaj yeem yog ib qho tsos mob ntawm lwm yam kab mob hauv qab . Piv txwv li, yog tias koj muaj mob qog noj ntshav, lossis yog tias koj muaj kab mob siab, lossis yog tias koj muaj tus mob autoimmune xws li mob rheumatoid arthritis, koj yuav muaj polyclonal gammopathy no. Yog li, thaum cov kws kho mob pom qhov no, lawv nrhiav, "Vim li cas lub cev tiv thaiv kab mob thiaj li raug txhawb nqa?"

Qhov txawv ntawm polyclonal thiab monoclonal gammopathy yog dab tsi?

Qhov no yuav zoo li tob me ntsis, tab sis cia peb ua kom yooj yim. Muaj ob hom qe ntshav dawb hauv peb cov ntshav hu ua 'B cell' thiab 'plasma cell'. Cov no yog cov uas ua cov tshuaj tiv thaiv kab mob ('Immunoglobulins') uas peb tau tham txog ua ntej.

• Polyclonal Gammopathy: Ntawm no, ob qho tib si 'B cell' thiab 'plasma cell' los ua ke los tsim ntau hom tshuaj tiv thaiv kab mob sib txawv. Ib yam li cov chaw tsim khoom sib txawv tsim ntau hom khoom sib txawv.
• Monoclonal Gammopathy:Qhov uas tshwm sim ntawm no yog tias tsuas yog 'cov hlwb ntshav' sib sau ua ke thiab ua ntau dhau ntawm ib hom tshuaj tiv thaiv kab mob, hu ua 'M protein'. Qhov no yog ib qho mob txawv me ntsis. Qhov no tuaj yeem cuam tshuam nrog cov mob qog noj ntshav xws li 'Multiple Myeloma'. Txawm li cas los xij, qee tus neeg kuj tuaj yeem tsim ib qho mob hu ua 'Monoclonal Gammopathy of Undetermined Significance' (MGUS). Yog tias qhov ntawd tshwm sim, koj tus kws kho mob yuav kuaj xyuas koj tsis tu ncua kom pom tias mob qog noj ntshav puas tab tom loj hlob. Yog li nws zoo kom paub txog qhov ntawd thiab.

Tseem Ceeb: Polyclonal gammopathy feem ntau tsis yog mob qog noj ntshav. Nws yog ib qho kev teb ntawm lub cev tiv thaiv kab mob.

Puas muaj lwm lub npe rau qhov no?

Yog, cov kws kho mob siv ntau lub npe rau tus mob polyclonal gammopathy. Cov npe tseem ceeb yog:

• Hypergammaglobulinemia: Qhov no hais txog kev nce ntxiv ntawm gamma globulin (ib hom antibody) hauv cov ntshav.
• Kab mob Polyclonal: Qhov no kuj yog lwm lub npe.

Cov ua rau muaj Polyclonal Gammopathy yog dab tsi?

Cov kws tshaj lij tseem tab tom tshawb nrhiav qhov ua rau muaj tus mob no. Txawm li cas los xij, nws feem ntau tshwm sim rau cov neeg uas muaj qee yam kab mob, cov kab mob autoimmune, lossis mob qog ntshav. Qee zaum, qee cov tshuaj noj rau lwm yam mob kuj tuaj yeem ua rau muaj kev pheej hmoo ntau ntxiv.

Cov tsos mob ntawm tus mob no yog dab tsi?

Feem ntau, polyclonal gammopathy tsis ua rau muaj cov tsos mob tshwj xeeb. Tej zaum koj yuav muaj cov tsos mob vim yog tus kab mob uas ua rau muaj gammopathy.

Xav txog tias koj muaj mob ntsws nrog rau kub taub hau thiab hnoos. Tom qab ntawd koj yuav pom cov tsos mob ntsig txog mob ntsws ntawd. Thaum tus kws kho mob kho nws, nws tuaj yeem kuaj ntshav thiab nrhiav pom qhov mob polyclonal gammopathy no los ntawm txoj hmoo. Ntawd yog, nws feem ntau pom thaum koj tab tom nrhiav lwm yam.

Qhov no puas yog ib yam dab tsi uas kis tau los ntawm tus kab mob lossis cov kab mob me me?

Tsis yog. Polyclonal gammopathy tsis yog tshwm sim los ntawm tus kab mob lossis cov kab mob me me. Nws yog ib qho kev teb ntawm lub cev tiv thaiv kab mob. Txawm li cas los xij, polyclonal gammopathy tuaj yeem tshwm sim los ntawm kev kis tus kab mob me me lossis cov kab mob me me. Uas yog, tus kab mob lossis cov kab mob me me ua rau lub cev tiv thaiv kab mob ua haujlwm.

Cov kws kho mob kuaj qhov no li cas? (Kev kuaj mob)

Cov kws kho mob feem ntau siv kev kuaj ntshav tshwj xeeb los kuaj mob polyclonal gammopathy. Qhov no hu ua Serum Protein Electrophoresis (SPEP) .

Yog tias koj tus kws kho mob twb tau kuaj pom tias koj muaj kab mob autoimmune, kev kis kab mob, kab mob siab, lossis mob qog noj ntshav, lossis xav tias koj muaj tus mob zoo li no, nws yuav ua qhov kev xeem 'SPEP' no kom paub tseeb tias koj lub cev tiv thaiv kab mob teb li cas.

Qhov kev xeem `SPEP` yuav pab nrhiav qhov no li cas?

Nws yooj yim heev. Tus kws kho mob yuav cov ntshav ntawm koj. Tom qab ntawd, hauv chav kuaj, lawv siv txoj kev no hu ua 'SPEP' los cais cov hom protein sib txawv hauv koj cov ntshav thiab xyuas lawv cov qib.

Cov protein no tuaj yeem qhia rau koj tus kws kho mob ntau yam txog kev noj qab haus huv ntawm koj lub cev tiv thaiv kab mob . Piv txwv li, lawv tuaj yeem muab cov lus qhia rau koj txog seb koj puas muaj kab mob siab (uas tuaj yeem ua rau muaj polyclonal gammopathy), lossis seb koj puas muaj kev kis kab mob lossis mob qog noj ntshav.

Puas muaj lwm yam kev kuaj mob los nrhiav qhov no?

Yog. Qee zaum, yog tias koj tus kws kho mob xav tias koj muaj kev kis kab mob rau koj lub paj hlwb, xws li mob meningitis, nws kuj tseem yuav kuaj koj cov kua dej cerebrospinal (CSF) , vim tias cov kev kis kab mob no kuj tuaj yeem ua rau muaj polyclonal gammopathy.

Cov kev kho mob rau qhov no yog dab tsi?

Qhov tseem ceeb uas yuav tsum nkag siab ntawm no yog tias polyclonal gammopathy yog ib qho kev teb ntawm lub cev tiv thaiv kab mob, tsis yog ib yam kab mob hauv nws tus kheej. Yog li ntawd, tsis muaj kev kho mob ncaj qha rau qhov mob no.

Koj tus kws kho mob yuav kho qhov mob uas ua rau lub cev tiv thaiv kab mob ua haujlwm ntau dhau. Piv txwv li, yog tias nws yog los ntawm kev kis kab mob, qhov kev kis kab mob yuav raug kho. Yog tias nws yog los ntawm tus kab mob autoimmune, yuav muab kev kho mob tsim nyog.

Thaum kho qhov mob tseem ceeb, koj tus kws kho mob yuav rov kuaj xyuas koj cov immunoglobulin kom pom tias polyclonal gammopathy puas tau txo qis lossis ploj mus.

Puas tuaj yeem tiv thaiv kev loj hlob ntawm Polyclonal Gammopathy?

Tu siab kawg li, cov kws tshawb nrhiav tseem tsis tau pom txoj hauv kev los tiv thaiv tus mob no. Vim tias nws feem ntau tshwm sim los ntawm lwm yam kab mob, qhov zoo tshaj plaws uas yuav tsum ua yog tiv thaiv tus kab mob uas yog qhov pib.

Kuv yuav paub li cas yog tias kuv muaj feem yuav mob no?

Yog tias koj muaj tej yam mob, koj muaj feem yuav mob polyclonal gammopathy ntau dua. Ib txhia ntawm cov mob no suav nrog:

• Cov mob autoimmune: Piv txwv li lupus, rheumatoid arthritis, thiab Sjogren's syndrome.
• Cov teeb meem ntshav: Piv txwv li, Sickle Cell Anemia.
• Mob qog ntshav: xws li mob leukemia thiab lymphoma.
• Lwm yam mob qog noj ntshav: Mob qog noj ntshav raum, Mob qog noj ntshav siab, Mob qog noj ntshav ntsws, Mob qog noj ntshav zes qe menyuam.
• Cov kab mob: Kab mob HIV, Kab mob Malaria, Kab mob Mononucleosis, Kab mob Pneumonia, Kab mob ntsws o.
• Kab mob siab: Kab mob siab autoimmune, Kab mob cirrhosis, Kab mob siab viral.
• Yog tias koj tau raug tshuaj asbestos .

Yog tias koj muaj ib qho ntawm cov mob no, lossis yog tias koj xav tias koj cov tsos mob hnyav zuj zus, nco ntsoov nrog koj tus kws kho mob tham. Nws tuaj yeem kuaj koj rau polyclonal gammopathy, yog tias tsim nyog.

Yog tias kuv muaj Polyclonal Gammopathy, kuv yuav tsum tau tos li cas?

Yog tias koj muaj polyclonal gammopathy, koj yuav muaj feem yuav kis kab mob thiab ntshav tsis txaus. Tab sis qhov xov xwm zoo yog tias nrog kev kho mob kom zoo rau tus kab mob uas ua rau muaj gammopathy, gammopathy thiab nws cov kev pheej hmoo cuam tshuam tuaj yeem ploj mus.

Qhov xwm txheej no puas tshwm sim tau ntau tshaj ib zaug?

Yog lawm, polyclonal gammopathy tuaj yeem tshwm sim ntau dua ib zaug, vim tias yog qhov ua rau rov tshwm sim dua, qhov kev tiv thaiv kab mob no kuj tuaj yeem rov tshwm sim dua.

Yog tias kuv muaj tus mob no, kuv yuav tsum saib xyuas kuv tus kheej li cas?

Qhov tseem ceeb tshaj plaws yog ua raws li koj tus kws kho mob cov lus qhia kom meej. Tshwj xeeb tshaj yog cov uas hais txog kev tiv thaiv koj tus kheej ntawm kev kis kab mob. Piv txwv li, tej yam yooj yim xws li hnav lub npog ntsej muag thaum mus rau qhov chaw muaj neeg coob coob thiab ntxuav koj txhais tes ntau zaus tuaj yeem ua qhov sib txawv loj.

Cov Lus Qhia Txog Kev Coj Mus Tsev

Zoo, yog li ntawm qhov peb tau tham txog, kuv vam tias koj muaj lub tswv yim zoo txog Polyclonal Gammopathy lossis Hypergammaglobulinemia.

• Hais yooj yim xwb, qhov no txhais tau tias koj lub cev tiv thaiv kab mob tsim ntau cov immunoglobulins (antibodies) dhau lawm .
• Qhov no qhia tau tias koj lub cev tiv thaiv kab mob ua haujlwm hnyav dhau lawm . Yuav tsum muaj ib qho laj thawj rau qhov ntawd.
• Koj tus kws kho mob yuav kho qhov mob uas ua rau muaj qhov no, thiab qhov mob gammopathy no feem ntau yuav zoo dua.

Yog li ntawd, tsis txhob ntshai tsuas yog vim muaj ib yam dab tsi zoo li no nyob hauv daim ntawv qhia. Tham nrog koj tus kws kho mob thiab nkag siab meej tias muaj dab tsi tshwm sim thiab yuav tsum ua dab tsi. Kuv xav kom koj noj qab nyob zoo!

`polyclonal gammopathy, hypergammaglobulinemia, immunoglobulin, antibody, lub cev tiv thaiv kab mob, SPEP, B cell, plasma cell