Puas muaj tej lub sij hawm koj xav tias muaj teeb meem nrog koj lub cev, zoo li koj cov tshuaj hormones tsis ua haujlwm zoo? Tej zaum nws yog vim muaj ib lub qog me me hauv koj lub hlwb. Thaum lub qog no ua haujlwm ntau dhau, nws tuaj yeem cuam tshuam rau ntau yam haujlwm tseem ceeb hauv koj lub cev, xws li kev loj hlob, kev ua haujlwm ntawm lub cev, thiab kev yug me nyuam. Niaj hnub no peb tab tom tham txog lub qog pituitary uas ua haujlwm ntau dhau, lossis hyperpituitarism.
Lub qog Pituitary yog dab tsi?
Hais yooj yim xwb, lub qog pituitary zoo li lub chaw tswj hwm uas tswj hwm peb lub cev txoj haujlwm. Nws yog ib lub qog me me li taum pauv nyob rau hauv qab ntawm peb lub hlwb. Nws yog lub taub hau ntawm peb lub endocrine system. Yog vim li ntawd qee zaum nws thiaj li hu ua "lub qog tswj hwm". Nws tswj hwm kev ua haujlwm ntawm lwm cov qog tseem ceeb xws li lub qog thyroid, lub qog adrenal, thiab cov qog gonadal.
Xav txog lub thermostat hauv peb lub tsev. Nws ib txwm kuaj xyuas qhov kub hauv tsev thiab xa cov cim rau lub tshuab cua sov thiab lub tshuab txias kom nws nyob rau tib theem, puas yog? Lub qog pituitary kuj ua haujlwm tib yam. Nws ib txwm saib xyuas kev ua haujlwm ntawm peb lub cev thiab xa cov cim rau cov kabmob thiab cov qog txog yam ua haujlwm dab tsi, thaum twg, thiab ntau npaum li cas. Cov cim no yog yam peb hu ua cov tshuaj hormones .
Lub qog pituitary txuas nrog ib feem ntawm peb lub hlwb hu ua hypothalamus. Lub hlwb qhia rau lub qog pituitary seb puas yuav tso tawm ntau dua lossis tsawg dua ntawm qee yam tshuaj hormones.
Cov tshuaj hormones tseem ceeb uas tsim los ntawm lub qog pituitary yog dab tsi?
Lub qog pituitary muaj peb ntu tseem ceeb. Txhua ntu tsim cov tshuaj hormones sib txawv. Cia peb saib seb lawv yog dab tsi thiab muaj dab tsi tshwm sim rau lawv.
| Ib feem ntawm lub qog | Cov tshuaj hormones | Lub luag haujlwm tseem ceeb |
|---|---|---|
| Lub Lobe pem hauv ntej (Kwv yees li 80% ntawm cov qog) | Adrenocorticotropic hormone (ACTH) | Nws ua rau cov qog adrenal ua haujlwm, tshwj xeeb tshaj yog kev tsim cov tshuaj hormones cortisol, uas tswj cov ntshav siab thiab kev tiv thaiv kab mob. |
| Kev Loj Hlob Hormone (GH) | Nws tswj kev loj hlob ntawm lub cev (tshwj xeeb tshaj yog rau cov menyuam yaus), kev ua haujlwm ntawm lub cev, thiab cov qauv ntawm lub cev (rog, cov leeg). | |
| Cov Tshuaj Hormone Txhawb Kev Ua Haujlwm ntawm Thyroid (TSH) | Nws ua rau lub qog thyroid ua haujlwm thiab pab tsim cov tshuaj hormones thyroid, uas tswj lub cev lub zog. | |
| Cov tshuaj Gonadotropins (LH thiab FSH) | Cov zes qe menyuam thiab noob qes raug txhawb kom tsim cov tshuaj hormones poj niam txiv neej uas tsim nyog rau kev yug me nyuam. | |
| Prolactin | Txhawb kom cov kua mis ntau ntxiv tom qab yug menyuam. | |
| Nruab Nrab Lobe | Cov tshuaj hormones txhawb nqa Melanocyte | Cuam tshuam rau daim tawv nqaij pigmentation. |
| Posterior Lobe | Cov tshuaj hormones tiv thaiv diuretic (ADH) | Tswj lub cev qhov sib npaug ntawm cov dej thiab electrolyte. |
| Oxytocin | Nws tswj cov kev sib cog lus ntawm lub tsev menyuam thiab kev tso kua mis tawm thaum yug menyuam. |
Cov kab mob dab tsi tshwm sim thaum lub qog pituitary ua haujlwm ntau dhau?
Thaum lub qog pituitary ua haujlwm ntau dhau, uas yog, thaum nws tsim cov tshuaj hormones ntau dhau, ntau yam mob tuaj yeem tshwm sim. Qhov ua rau qhov no yog qog tsis yog mob qog noj ntshav (benign) uas loj hlob hauv lub qog. Qhov no hu ua pituitary adenoma .
Nov yog qee yam kab mob tseem ceeb uas tuaj yeem tshwm sim vim qhov no:
- Cushing's syndrome: Yog tias lub qog pituitary tso tawm ACTH ntau dhau, cov qog adrenal tsim cov cortisol ntau dhau, uas tuaj yeem cuam tshuam lub cev metabolism thiab lub cev tiv thaiv kab mob.
- Acromegaly: Ib qho mob uas tshwm sim thaum lub cev cov tshuaj hormones loj hlob (GH) siab dhau. Qhov no ua rau cov pob txha thiab cov nqaij loj hlob tsis zoo.
- Kev mob thyroid ntau dhau: Yog tias lub qog pituitary tsim TSH ntau dhau (qhov no tsis tshua muaj), cov qog thyroid yuav ua haujlwm ntau dhau. Qhov no tuaj yeem ua rau muaj tej yam xws li kev ua kom lub cev zom zaub mov ntau ntxiv, lub plawv dhia ceev ceev, thiab kev ntxhov siab.
- Prolactinoma: Ib qho qog hauv lub qog pituitary uas ua rau muaj ntau cov tshuaj hormones prolactin. Qhov no tuaj yeem cuam tshuam rau cov txheej txheem kev yug me nyuam ntawm cov poj niam thiab cov txiv neej.
Vim tias cov mob no tuaj yeem ua rau mob hnyav, nws yog ib qho tseem ceeb heev uas yuav tsum mus ntsib koj tus kws kho mob tam sim ntawd yog tias koj muaj ib qho ntawm cov tsos mob no.
Cov tsos mob ntawm cov mob no yog dab tsi?
Cov tsos mob uas cuam tshuam nrog txhua yam mob sib txawv. Cia peb saib seb cov no yog dab tsi. Saib seb koj puas muaj cov tsos mob no thiab.
| Mob | Cov tsos mob uas yuav tshwm sim |
|---|---|
| Cushing's syndrome |
|
| Acromegaly |
*Thaum qhov no tshwm sim rau cov menyuam yaus, nws hu ua 'gigantism.' Lawv tuaj yeem loj hlob siab txawv txawv. |
| Kev mob hyperthyroidism |
|
| Prolactinoma | Rau cov poj niam:
Rau cov txiv neej:
*Rau ob sab: Tej zaum yuav muaj mob taub hau thiab teeb meem pom kev (vim yog qhov qog loj zuj zus thiab nias rau ntawm cov hlab ntsha pom kev). |
Hyperpituitarism hauv cov menyuam yaus
Tus mob no tsis tshua muaj rau cov menyuam yaus. Thaum nws tshwm sim, feem ntau nws yog los ntawm ib qho qog me me, tsis yog mob qog hu ua pituitary microadenoma. Tus mob feem ntau pom muaj rau cov menyuam yaus yog prolactinoma.
- Rau cov ntxhais: Tej zaum yuav muaj kev laus qeeb thiab tsis muaj hli (amenorrhea).
- Rau cov tub hluas: Thaum lub qog loj hlob thiab nias rau ntawm cov hlab ntsha, nws tuaj yeem ua rau mob taub hau, muaj teeb meem pom kev, thiab lwm yam teeb meem. Nws kuj tseem tuaj yeem ua rau lub hnub nyoog laus qeeb lossis muaj teeb meem loj hlob.
Vim li cas ho ua li no?
Feem ntau qhov mob hyperpituitarism yog tshwm sim los ntawm ib qho qog hauv lub qog pituitary. Tsis paub meej tias yog vim li cas cov qog no tshwm sim.
- Cov qog nqaij hlav tsis muaj mob: Qhov no yog qhov ua rau feem ntau tshwm sim. Nyob ntawm seb hom cell uas cov qog nqaij hlav ua los ntawm, nws pib tso tawm ntau dhau ntawm ib lossis ob hom tshuaj hormones.
- Tej yam mob uas los ntawm noob caj: Qee zaum, cov qog no tuaj yeem tshwm sim los ntawm tej yam mob uas los ntawm noob caj xws li Multiple Endocrine Neoplasia type 1 (MEN1) .
- Mob qog noj ntshav: Tsis tshua muaj, mob qog noj ntshav lossis kab mob ntawm hypothalamus tuaj yeem ua rau qhov no.
Yuav paub qhov mob no li cas?
Tam sim no, thaum koj mus ntsib kws kho mob uas muaj cov tsos mob no, nws yuav sau keeb kwm kom ntxaws thiab mloog koj cov tsos mob. Tom qab ntawd, lawv yuav xaj ntau qhov kev kuaj mob kom paub tseeb tias koj tau kuaj mob.
- Kev kuaj ntshav thiab zis: Cov kev kuaj no ntsuas cov tshuaj hormones hauv koj cov ntshav lossis zis. Piv txwv li, lawv kuaj xyuas cov tshuaj prolactin, cortisol, thiab cov tshuaj hormones loj hlob.
- Kev Ntsuas Duab: Yog tias cov kev kuaj hauv chav kuaj qhia tias muaj qog, yuav muaj kev ntsuas los xyuas kom meej. Qhov no tuaj yeem qhia meej tias qog nyob qhov twg thiab nws loj npaum li cas.
- MRI (Magnetic Resonance Imaging) Scan: Qhov no yog txoj kev siv ntau tshaj plaws.
- CT (Computed Tomography) Kev Ntsuas: Yog tias koj muaj lub tshuab ua pacemaker, kev ntsuas CT yuav raug ua vim tias MRI ua tsis tau.
Yuav kho li cas?
Nyob ntawm koj tus mob, ib lossis ntau txoj kev kho mob yuav siv tau ua ke.
Tshuaj
Muaj tej lub sij hawm, cov tshuaj yuav muab los tswj cov tshuaj hormones. Piv txwv li, yog tias muaj prolactinoma, cov tshuaj yuav muab los txo cov prolactin thiab ua rau cov qog nqaij hlav me. Cov tshuaj kuj qee zaum siv los ua kom cov qog nqaij hlav loj me ua ntej phais.
Kev phais mob
Hauv cov mob xws li acromegaly lossis Cushing's syndrome, qhov mob qog nqaij hlav raug tshem tawm los ntawm kev phais. Qhov kev phais mob feem ntau hu ua transsphenoidal adenomectomy . Hauv qhov no, tus kws phais mob ua ib qho kev phais me me los ntawm lub qhov ntswg lossis daim di ncauj sab saud, mus txog rau hauv lub qog pituitary, thiab tshem tawm qhov mob qog nqaij hlav. Txawm hais tias qhov no yog kev phais mob uas nyuaj heev, qhov feem pua ntawm kev vam meej yog ntau dua 80% thaum ua los ntawm tus kws phais mob uas muaj kev paub dhau los.
Kev kho mob hluav taws xob
Rau cov neeg uas tsis tuaj yeem phais tau, lossis yog tias qee qhov ntawm lub qog tseem nyob tom qab phais, kev kho mob hluav taws xob yuav siv. Qhov no suav nrog kev tsom mus rau lub teeb hluav taws xob muaj zog heev rau ntawm lub qog thiab rhuav tshem cov cell.
Lub zeem muag zoo li cas?
Rau ntau tus neeg, qhov kev cia siab rau tus mob no yog qhov zoo. Txawm hais tias nws tsis tuaj yeem kho tau, nrog kev kho mob thiab kev tswj hwm kom zoo, ntau tus neeg tuaj yeem tswj lawv cov tsos mob thiab ua neej nyob zoo, zoo siab, thiab muaj txiaj ntsig. Qee zaum, koj yuav tsum tau noj tshuaj lossis nyob hauv kev saib xyuas ntawm kws kho mob ntev. Qhov tseem ceeb tshaj plaws yog kom sib cuag nrog koj tus kws kho mob tsis tu ncua thiab qhia rau nws paub txog txhua qhov kev hloov pauv hauv koj cov tsos mob.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Lub qog pituitary zoo li tus "tswj hwm" ntawm peb lub cev. Cov tshuaj hormones uas nws tso tawm tswj ntau yam haujlwm tseem ceeb hauv peb lub cev.
- Yog tias lub qog no ua haujlwm ntau dhau, ntau yam kab mob xws li hyperpituitarism, Cushing's syndrome, thiab acromegaly tuaj yeem tshwm sim.
- Yog koj pom muaj kev hloov pauv sai sai, tsis tshua muaj xws li qhov hnyav ntawm lub cev, lub ntsej muag zoo li cas, daim tawv nqaij, lossis lub voj voog ntawm lub hli, ua tib zoo mloog.
- Yog koj muaj cov tsos mob no, tsis txhob ntshai. Mus ntsib kws kho mob ua ntej thiab tau txais kev qhia.
- Yog kuaj pom thiab kho kom zoo, ntau yam mob no yuav tswj tau zoo thiab tib neeg tuaj yeem ua neej nyob li qub.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus