Yu de wɔri bɔt yu pikin in wɛlbɔdi? Dɔn yu nid fɔ no bɔt NIPT (Noninvasive Prenatal Testing)!

Bikɔs yu de tink naw fɔ bi mama, yu go mɔs de tink bɔku bɔt di wɛlbɔdi fɔ yusɛf ɛn yu smɔl pikin we de na yu bɛlɛ, nɔto so? So tide wi go tɔk bɔt wan spɛshal tɛst we dɛn kin du we uman gɛt bɛlɛ. Dɛn kɔl dis NIPT (Noninvasive Prenatal Testing). Dis kin mek yu lan sɔm impɔtant tin dɛn bɔt yu pikin in wɛlbɔdi we nɔ go ambɔg yu ɔ di pikin.

Wetin na NIPT (Noninvasive Prenatal Testing)?

Fɔ tɔk am simpul wan, NIPT na tɛst we dɛn kin du we yu gɛt bɛlɛ fɔ si if yu pikin we nɔ bɔn yet gɛt sɔm prɔblɛm dɛn wit in kromozom . Fɔ ɛgzampul, i kin chɛk fɔ si if pɔsin gɛt prɔblɛm dɛn lɛk Daun sindrom ( Trisomy 21) , Trisomy 18 ( Edwards syndrome) , ɛn Trisomy 13 (Patau syndrome) . I kin tɛl yu bak di sɛks we yu pikin gɛt.

Dɛn kin du dis wit blɔd sɛmpul we dɛn tek frɔm yu. Nɔ sɔprayz fɔ no se yu blɔd gɛt smɔl smɔl tin pan yu pikin in DNA (Deoxyribonucleic Acid) . DNA na wetin wi jin ɛn kromozom dɛn mek wit. I tan lɛk di bluprint fɔ wi bɔdi. So na bay we dכkta dεn tεst dεn DNA fragmεnt dεm ya, dεn kin gεt sכm aidia fכ di pikin in jεnεtik infכmeshכn. Dɛn kin sɛn dis blɔd sɛmpul na lab fɔ mek dɛn tɛst am. Bɔt mɛmba se NIPT nɔ kin ebul fɔ no ɔl di kromozom ɔ jɛnɛtik kɔndishɔn.

Dɛn kin kɔl dis NIPT tɛst ɔda nem dɛn. Sɔm pipul dɛn kin kɔl am DNA skrinin we nɔ gɛt sɛl ɔ cfDNA skrinin . Ɔda pipul dɛn kin kɔl am nɔ-invasive prenatal screening ɔ NIPS . Nɔ ala if yu yɛri dɛn nem ya, dɛn ɔl na di sem tɛst.

I rili impɔtant fɔ no se dis na tɛst fɔ chɛk pɔsin , nɔto tɛst fɔ no if pɔsin gɛt sik . Dis min se i jɔs de tɛl yu aw yu pikin go gɛt wan sik ɔ aw i nɔ go gɛt dis sik. I nɔ go ebul fɔ tɔk fɔ tru se, ‘Yɛs, yu pikin gɛt dis sik’ ɔ ‘Nɔ, yu pikin nɔ gɛt dis sik.’

If yu disayd fɔ du di NIPT tɛst ɔ yu nɔ disayd fɔ du am, na yu disayd nɔmɔ. Yu dɔktɔ go gi yu infɔmeshɔn bɔt dis ɛn ɛp yu fɔ disayd fɔ du di bɛst tin fɔ yu.

Wetin ɛksaktɔli di NIPT tɛst de luk fɔ?

As wi bin dɔn tɔk, NIPT nɔ kin ebul fɔ no ɔl di kromozom kɔndishɔn ɔ di prɔblɛm dɛn we kin apin we dɛn bɔn pikin. Bɔku tɛm, NIPT tɛst dɛn kin luk fɔ:

• Daun sindrom (Trisomy 21) .
• Trisɔmi 18. Di wan dɛn we de wok
• Trisɔmi 13. Di wan dɛn we de stɔdi
• abnɔmal tin dɛn we gɛt fɔ du wit di kromozom dɛn we de na di sɛks (X ɛn Y) .

Daun sindrom, trisomy 18, ɛn trisomy 13 kin kɔmɔt frɔm wan ɛkstra kromozom. we dεn tεst di sεks kromozom dεm kin no if di pikin in man εn uman εn i kin chεk bak fכ eni chenj na di nכmal nכmba fכ di sεks kromozom dεm. di kכmכn sεks kromozom kכndyushכn dεm na Turner syndrome , Klinefelter syndrome , Triple X syndrome, εn XYY syndrome . Bɔt mɛmba se nɔto ɔl di NIPT tɛst dɛn kin no ɔl dɛn tin ya. So i impɔtant fɔ tɔk to yu dɔktɔ bɔt wetin yu NIPT tɛst go luk fɔ.

Wetin mek dɛn kin du dis NIPT tɛst? Udat i bɛtɛ fɔ?

NIPT de εp fכ no di risk fכ bכn pikin wit wan kromozom abnכmaliti. Dɔktɔ dɛn kin tɛl yu fɔ du dis tɛst pan dɛn tin ya:

• If yu dɔn gɛt pikin we gɛt prɔblɛm wit in kromozom.
• If wan ɔltra saund skan yu bin dɔn sho se di pikin kin gɛt sɔm abnɔmal tin.
• If yu dɔn gɛt wan skrinin tɛst bifo we sho se prɔblɛm kin de.

Di American College of Obstetricians and Gynecologists (ACOG) bin de rikɔmɛnd NIPT nɔmɔ if yu gɛt bɛlɛ we gɛt bɔku prɔblɛm . Dat min se, sɔntɛm, if yu dɔn pas 35 ia, ɔ if sɔmbɔdi na yu famili dɔn gɛt wan pan dɛn sik ya. Bɔt naw dɛn de se ɔl uman dɛn we gɛt bɛlɛ, ilɛksɛf dɛn gɛt risk, dɛn fɔ tɛl dɛn bɔt NIPT ɛn gi dɛn di chans fɔ gɛt am.

Dipen pan di rizɔlt fɔ di NIPT tɛst, yu ɔbstetrishan kin tɛl yu fɔ du tɛst fɔ no if yu gɛt di sik . As wi bin dɔn tɔk bifo tɛm, wan skrinin tɛst de ɔlrɛdi tɛl yu di prɔbabiliti. di diagnostik tεst na di wan we kin gi difinitiv ‘yes’ כ ‘no’ ansa fכ if yu pikin gεt kכndyushכn.

Ustɛm dɛn fɔ du di NIPT tɛst we uman gɛt bɛlɛ?

di NIPT tεst kin bi afta 10 wiks we uman bεlε, bכt dεn kin du am εni tεm te dεn bכn di pikin . Bɔrku tɛm, dɛn nɔ kin du am bifo 10 wik. dis na biכs i kin bi se i nכ go bכn inof fεtal DNA na di mama in bכdi bifo da tεm de fכ du di tεst kכrekt wan.

Aw di NIPT tɛst dɛn kɔrɛkt?

Dis na kwɛstyɔn we bɔku pipul dɛn kin aks. Di kɔrɛkt we aw di tɛst kɔrɛktI dipen pan us kɔndishɔn dɛn de tɛst. Dɔn bak, tin dɛn lɛk if yu de ɛkspɛkt twins, if yu de kɛr pikin fɔ ɔda pɔsin (sɔrogɛt bɛlɛ), ɔ if yu fat kin afɛkt di NIPT rizɔlt.

NIPT jεnarali de bכt 99% akכrd fכ dεtekt Daun sεndrכm. I kin bi smɔl smɔl fɔ no trisomies 18 ɛn 13. Ɔl togɛda, NIPT gɛt smɔl lay lay pɔsitiv pas ɔda tɛst dɛn we dɛn kin du bifo dɛn bɔn pikin, lɛk di kwad skrin. Dis min se di tɛst nɔ kin gi lay lay pɔsitiv we di pikin nɔ afɛkt.

Di NIPT tɛst kin no if di pikin na man ɔ uman?

yes, di NIPT tεst kin prεdikt di sεks fכ di pikin. Bɔku mama ɛn papa dɛn kin rili want fɔ no dis, nɔto so?

I nid fɔ mek dɛn du NIPT tɛst we uman gɛt bɛlɛ?

Nɔ, dis nɔto tin we pɔsin fɔ du. Dis na sɔntin we pɔsin kin disayd fɔ du. Na nɔmal tin fɔ gɛt kwɛstyɔn bɔt dis. Yu dɔktɔ go tɛl yu ɔl bɔt di ɔda tin dɛn we yu kin du fɔ chɛk yu pikin bifo yu bɔn, lɛk NIPT. Bɔku tin kin afɛkt di disayd fɔ gɛt NIPT. If yu gɛt prɔblɛm fɔ disayd, ɔ if yu want fɔ tɔk mɔ bɔt dis skrinin, wan pɔsin we de advays yu bɔt yu jɛnɛtiks kin ɛksplen dɛn tin ya we yu kin du fɔ tɛst yu bifo yu bɔn ɛn ɛp yu fɔ pik di wan we bɛtɛ fɔ yu.

Aw dɔktɔ dɛn kin du dis NIPT tɛst?

Dis na tin we rili simpul. Ɔl wetin yu dɔktɔ de du na fɔ tek blɔd sɛmpul frɔm wan vein we de na yu an . dis bכdi sεmpl dεn kin sεnd to lab fכ chεk fכ eni abnכmaliti na di pikin in DNA.

Wi ɔl gɛt DNA insay wi sɛl dɛn. Dɛn sɛl dɛn ya de sheb ɔltɛm ɛn mek nyu sɛl dɛn. We di sɛl dɛn brok, smɔl smɔl DNA (DNA fragmɛnt dɛn) kin dɔn na wi blɔd. We yu gɛt bɛlɛ, na smɔl pat pan yu pikin in DNA de go na yu blɔd. Dɛn kɔl dis DNA we nɔ gɛt sɛl, ɔ cfDNA . di NIPT tεst de luk fכ di pat dεm pan yu pikin in DNA na yu bכdi.

i impɔtant fɔ mɛmba se i kin tek lɛk 10 wiks fɔ mek di pikin in DNA kam togɛda na yu blɔd. na dat mek dεn nכ de du dis tεst te 10 wiks insay di bεlε.

Ɛni risk de wit di NIPT tɛst?

NIPT tɛst dɛn rili sef. No risk nɔ de fɔ di pikin. Bikɔs i jɔs nid fɔ tek smɔl blɔd frɔm di mama we gɛt bɛlɛ. So natin nɔ de fɔ wɔri bɔt.

Ustɛm a go gɛt mi tɛst rizɔlt?

Sɔntɛnde i kin tek tu wiks fɔ gɛt di rizɔlt fɔ di NIPT tɛst.Yu kin go. Bɔt tɛm kin de we yu kin gɛt di rizɔlt bifo tɛm. Yu dɔktɔ kin gɛt di rizɔlt fɔs. Dɔn i go tɛl yu bɔt dɛn rizɔlt dɛn de.

Wetin di NIPT tɛst rizɔlt se?

Bikɔs NIPT na skrinin tɛst, i nɔ de gi ‘yes’ ɔ ‘nɔ’ ansa fɔ no if yu pikin gɛt wan kɔndishɔn. Di rizulyt sho if yu pikin de pan risk fɔ gɛt dis sik pasmak ɔ i nɔ de go . Sɔntɛnde, yu tɛst rizɔlt kin at fɔ ɔndastand smɔl. So if yu nɔ shɔ, aks yu dɔktɔ fɔ mek i no yu klia wan.

Bɔku lab dɛn kin gi difrɛn rizɔlt fɔ ɛni kɔndishɔn we dɛn de tɛst fɔ. Fɔ ɛgzampul, yu kin gɛt pɔsitiv (high risk) rizɔlt fɔ Trisomy 13, bɔt yu kin gɛt negatif (lɔ risk) rizɔlt fɔ Down syndrome.

Dɔn bak, sɔm tɛm dɛn nɔ kin gɛt ɛni rizɔlt bikɔs di pikin in DNA nɔ de na yu blɔd, ɔ dɛn nɔ kin ebul fɔ no di pikin in DNA fayn fayn wan. If na so i bi, yu kin mek dɛn ripit di NIPT tɛst. If na so i bi, yu dɔktɔ go gi yu di bɛst advays.

Wetin fɔ du if di rizɔlt na pɔsitiv/hay risk?

If di NIPT tɛst sho se yu pikin de pan denja fɔ gɛt prɔblɛm wit in kromozom, yu dɔktɔ go tɛl yu fɔ du tɛst fɔ no if yu gɛt di sik . Dɛn tɛst ya kin rili se ‘yes’ ɔ ‘nɔ’ if wan kɔndishɔn de. Dɛn tɛst ya na:

• Amniocentesis: dis involv fכ pul sכm sכm di amniotic fluid na yu uterus. dis tεst kin bi afta 15 wiks we uman bεlε.
• Chorionic Villus Sampling (CVS): dis tεst de tek sεmpl fכ sεl dεm frכm di plasεnta. Dɛn kin sɛn dis sɛl sɛmpul to wan lab fɔ mek dɛn tɛst am. dis kin bi bitwin 10 εn 13 wiks we uman bεlε.

I rili impɔtant fɔ tɔk gud gud wan wit yu dɔktɔ bɔt yu NIPT rizɔlt ɛn gɛt ɔl di infɔmeshɔn we yu nid bɔt wetin fɔ du nɛks.

Yu tink se di NIPT tɛst kin rɔng fɔ Daun sindrom?

Bikɔs NIPT na skrinin tɛst, i nɔ kɔrɛkt 100%. Na dat mek wi se i jɔs de sho se i gɛt prɔblɛm. So i impɔtant fɔ tɔk to yu dɔktɔ fɔ no mɔ bɔt yu rizɔlt ɛn di nɛks tin dɛn we yu go du.

I fayn fɔ mek yu gɛt di NIPT tɛst?

I de to yu fɔ disayd if fɔ du prɛnatal skrinin tɛst lɛk NIPT ɔ ɔda jenɛtik tɛst. Yu dɔktɔ kin ansa ɛni kwɛstyɔn we yu gɛt. Bɔt te go, na yu fɔ disayd aw wan tin we nɔ fayn na yu jɛnɛtik ɔ kromozom go afɛkt yu ɛn yu famili, bay di patikyula tin we de apin to yu.

Dɛn kwɛstyɔn ya go ɛp yu fɔ disayd fɔ du sɔntin:

• Aw a go fil if wan skrinin rizɔlt na pɔsitiv?
• A go rɛdi fɔ du diagnostik tɛst lɛk amniocentesis ɔ CVS?
• If a kam fɔ no se mi pikin gɛt wan sik we dɛn kɔl jenɛtik, ɔ i de pan denja fɔ gɛt wan sik we dɛn kɔl jenɛtik, a go mek ɛni chenj?
• We a no dis infɔmeshɔn, dat go mek a fil bad ɔ wɔri, ɔ i go ɛp mi fɔ rɛdi fɔ kia fɔ di pikin?
• We a no dis infɔmeshɔn, dat go ɛp mi dɔktɔ dɛn fɔ kia fɔ mi pikin fayn fayn wan?

Aw bɔku di NIPT tɛst de kɔst?

Di kɔst fɔ NIPT tɛst kin difrɛn. Bɔrku pan di wɛl bɔdi inshɔrans kɔmni dɛm kin kɔba bɔrku (ɔ ivin ɔl) pan dis kɔst. Sɔm kin at least kɔba sɔm. So i fayn fɔ chɛk wit yu inshɔrans kɔmni bifo yu du di tɛst. If yu nɔ gɛt inshɔrans, ɔ yu inshɔrans nɔ de kɔba NIPT tɛst, yu kin pe fɔ am yusɛf.

Yu kin du NIPT na 14 wik?

Yes, dεn kin du NIPT εni tεm afta 10 wiks we uman bεlε. Dat min se prɔblɛm nɔ de ivin we i ol 14 wik.

Wetin a fɔ aks mi dɔktɔ bɔt di NIPT tɛst?

Fɔ gɛt tɛst lɛk NIPT na pɔsin in yon disayd. Yu kin gɛt kwɛstyɔn bɔt wetin yu rizɔlt min, ɔ if yu fɔ gɛt di NIPT tɛst. Nɔ fred fɔ aks kwɛstyɔn. Mɛmba se na yu nɔmɔ go disayd wetin bɛtɛ fɔ yu ɛn yu famili.

Na sɔm kɔmɔn kwɛstyɔn dɛn we yu kin aks yu dɔktɔ:

• If yu bin bi mi, yu go geht di NIPT tehst?
• If mi skrinin test de positif, wetin na di nɛks tin dɛn we a fɔ du?
• Yu tink se pɔsin de we de advays mi jɛnɛtiks fɔ tɔk bɔt di tin dɛn we a kin disayd fɔ du?
• Wetin na di prɔbabiliti fɔ mek pɔsin gɛt lay lay pɔsitiv?

Tek mɛsej na os

Okay, so di NIPT tεst na wan mεtכd we dεn kin rili rili rili fכ skrεn bifo uman bכn we de ases di risk fכ di kromozom dizכrd dεm na di pikin we dεn bכn. Dis tεst kin gi infכmeshכn bak bכt di pikin in man εn uman. di NIPT tεst nכ de sho se i gεt sik – i de כnli sho se di pikin go gεt wan patikyula kכndishכn. Afta dɛn dɔn gɛt di NIPT rizɔlt, dɛn kin advays fɔ du diagnostik tɛst. Tεst dεm bifo dεn bכn lεk NIPT nכto fכ du am, εn if yu fכ du am כ nכ de du am, i de כlmost to yu.Tɔk to yu dɔktɔ ɔ pɔsin we de advays yu bɔt yu jɛnɛtiks bɔt di tin dɛn we de mɔna yu. I impɔtant fɔ ɔndastand gud gud wan wetin di tɛst de luk fɔ ɛn wetin di rizɔlt min, ɛn disayd fɔ du sɔntin we yu no gud gud wan. A de wish yu ɛn yu pikin ɔl di bɛst!

` NIPT, Noninvasive Prenatal Testing, prenatal testing, Down syndrome, di kromozom abnכmaliti, bεlε, cfDNA, di pikin in hεlth