Yu dɔn mek dɛn chɛk yu ɛmoglobin? Lɛ wi tɔk bɔt di Ɛmoglobin Ilɛktrofɔrɛsis tɛst!

Adu! Tide wi go tɔk bɔt blɔd tɛst we kin bi nyu tin fɔ yu smɔl, bɔt i rili impɔtant fɔ no sɔm sik dɛn. Dis na wan tɛst we dɛn kɔl Ɛmoglobin Ilɛktrofɔrɛsis . Sɔntɛm yu dɔktɔ dɔn tɛl yu fɔ du dis tɛst, ɔ yu dɔn yɛri dis nem sɔmsay. Pan ɔl we di nem lɔng smɔl, nɔ fred! I rili simpul. Wi go tɔk bɔt ɔl dis klia wan insay dis atikul tide.

Wetin na Ɛmoglobin Ilɛktrofɔrɛsis?

Fɔ tɔk am simpul wan, dis na we fɔ chɛk wan prɔtin we dɛn kɔl ɛmoglobin insay wi rɛd blɔd sɛl dɛn. Yu go mɛmba se ɛmoglobin na impɔtant prɔtin we de kɛr ɔksijɛn go ɔlsay na wi bɔdi ɛn gi rɛd blɔd sɛl dɛn rɛd kɔlɔ. Di rayt we aw dis ɛmoglobin de mek, na wi jin dɛn de kɔntrol am.

Bɔt sɔntɛnde, sɔm chenj dɛn, ɔ chenj dɛn kin apin na di jin dɛn we de kɔntrol di ɛmoglobin. We dis apin, insted fכ di hεlty rεd blɔd sεl dεm, di rεd blɔd sεl dεm we dεn dכn pwεl, we nכ de wok fayn kin bigin fכ fכm. Dɛn sɛl ya we dɔn pwɛl kin brok kwik kwik wan, we kin mek pɔsin gɛt tin dɛn lɛk anemia , ɔ siriɔs sik dɛn we gɛt fɔ du wit blɔd lɛk sikɛl sɛl anemia ɛn thalassemia .

So, dis ɛmoglobin ilɛktrɔfɔrɛsis tɛst de mek dɔktɔ dɛn ebul fɔ no if dɛn kayn tin ya de. Dɔn bak, dis tɛst na wan pan di smɔl tɛst dɛn we dɛn kin du pan pikin dɛn we dɛn jɔs bɔn. I de ɛp fɔ no kwik kwik wan bɔt sik dɛn we nɔ kin bɔku bɔt we kin rili siriɔs lɛk sikɛl sɛl anemia.

Wetin na di difrɛns bitwin ɛmoglobin tɛst ɛn ɛmoglobin ilɛktrɔfɔrɛsis?

Dis na di say bak we bɔku pipul dɛn kin kɔnfyus. Nɔmal ɛmoglobin tɛst de sho aw di ɛmoglobin de na yu rɛd blɔd sɛl dɛn. Dat min se i de chɛk if yu ɛmoglobin smɔl, ay, ɔ nɔmal.

Bɔt di ɛmoglobin ilɛktrɔfɔrɛsis tɛst de du sɔntin we dip pas dat fa fawe. I de chɛk di difrɛn kayn ɛmoglobin we de na yu rɛd blɔd sɛl dɛn, ɛn ɔmɔs pan ɛni wan pan dɛn de. Yu ɔndastand di difrɛns? Wan de luk di amount, di oda wan de luk di kayn en amount of dem kayn.

So, wetin na dɛn kayn ɛmoglobin ya?

Bɔku tɛm, dɔktɔ dɛn kin pe atɛnshɔn pan 4 men kayn ɛmoglobin dɛn we dɛn de du dis tɛst. Lɛ wi lan smɔl bɔt dɛn.

• Ɛmoglobin A1 ɛn A2 (HgbA1 ɛn HgbA2): Dis kayn ɛmoglobin we dɛn kɔl ɛmoglobin A1 na di kayn we we bɔku pas ɔl na di rɛd blɔd sɛl dɛn fɔ big pɔsin we gɛt wɛlbɔdi. εmoglobin A2 na sכm kayn εmoglobin, we de mek lεk 2% to 3% pan di tכtal εmoglobin. Dɛn kin kɔl dɛn tin ya bak "adult hemoglobins."

• εmoglobin F (HgbF): dεn kכl dis "Fεtal εmoglobin".as di nem sho, dis kayn HgbF de insay di rεd bכdi sεl dεm fכ di pikin dεm, nyu bכbi dεm, εn pikin dεm we ol lεk 3 ia. Bɔt i kin bi abnɔmal fɔ gɛt bɔku ay pas di nɔmal lɛvɛl fɔ HgbF na di blɔd fɔ big pɔsin.

• Ɛmoglobin S (HgbS): Dis kayn ɛmoglobin na wan men tin we kin mek pɔsin nɔ gɛt sik na sik . Siklɔs anemia na siriɔs sik we de insay di grup fɔ siklɛt sik dɛn . Dis sik kin mɔna pipul dɛn we kɔmɔt na Afrika . HgbS de mek di rεd bכdi sεl dεm chenj to sikl shep, we kin blכk di bכdi vεsul dεm.

• Ɛmoglobin C (HgbC): Dis kayn ɛmoglobin gɛt fɔ du wit wan sik we dɛn kɔl ɛmolaytik anemia . Dis na di sik we di rɛd blɔd sɛl dɛn kin pwɛl kwik kwik wan pas di nɔmal sɛl dɛn ɔ dɛn kin shɔt fɔ liv. Lεk sikl sεl anemia, dis HgbC kכndyushכn kin kכmכn bak pan pipul dεm we kכmכt na Afrika .

Naw i dɔn klia to yu se difrɛn kayn ɛmoglobin de, ɛn ɛni wan pan dɛn gɛt patikyula wok ɛn ifɛkt dɛn.

Aw dɛn kin du dis tɛst? Aw dɛn kin tek di blɔd sɛmpul?

Fɔ du dis tɛst, wi jɔs nid fɔ tek blɔd sɛmpul. Dɔktɔ dɛm, difrɛn we dɛn de fɔ tek dis blɔd sɛmpul. Lɛ wi si wetin dɛn bi.

1. We yu de pul blɔd na di venɔs

Dis na di kɔmɔn we we dɛn kin yuz fɔ gɛda blɔd frɔm big pipul ɛn pikin dɛn we dɔn big. Sɔntɛm yu dɔn gi blɔd dis we.

• Fɔs, nɔs ɔ dɔktɔ go klin di say we yu vein de na yu an wit rɔm.
• Dɔn, dɛn kin put tɔnik na yu an ɛn tay am, ɛn aks yu fɔ swɛt yu an. Dis go mek i izi fɔ si di vein dɛn ɛn i go izi fɔ pul di blɔd.
• Neks, di nɔs kin put nidul insay di vein. Dis tɛm ya, yu kin fil smɔl pen, lɛk se ant bit yu. Bɔt i kin jɔs las fɔ sɔm sɛkɔn dɛn.
• Kɔlekt di blɔd we yu nid insay wan smɔl vayl ɛn sɛn am na di lɛb fɔ mek dɛn tɛst am.
• Afta dɛn dɔn pul di blɔd, dɛn kin put smɔl plasta na di say we dɛn put di nidul. Di say kin brus smɔl ɛn i kin ivin tɔn blu fɔ sɔm dez. Dis na nɔmal tin, nɔ wɔri.

2. Finga stik

Bɔku tɛm dɛn kin yuz dis we fɔ tek blɔd sɛmpul frɔm yɔŋ pikin dɛn.

• Dis min se yu fɔ chuk di pikin in finga wit smɔl inschrumɛnt ɛn tek sɔm drop blɔd.
• Dɛn kin put di blɔd sɛmpul pan wan spɛshal tɛst strip we dɛn mek ɔ insay wan smɔl bɔtul.
• Sɔntɛnde, tin dɛn de we kin gɛda blɔd ɛn put am di sem tɛm. Dis na wan we we rili kwik ɛn izi.

3. Il stik na di il

Dɛn kin du dis as pat pan di nyu bɔn pikin dɛn wɛlbɔdi skrinin. dis tεst kin bi insay 48 awa afta dεn bכn di pikin.

• insay dis, dεn kin put sכmכl nidul insay di pikin in il כndasay εn dεn kin gεt fכ dכp blכd.
• Dis tɛm ya, di mama ɔ di papa kin ol di pikin. Dɔn di pikin sɛf go fil fayn.
• Dɛn kin gɛda di blɔd sɛmpul ɛn sɛn am na di lɛb afta dɛn dɔn smɛl am pan wan strip pan pepa.
• Dɛn kin yuz dɛn tɛst ya fɔ chɛk nyu bɔbɔ fɔ sayn dɛn we nɔ kin bɔku bɔt we dɛn kin trit lɛk sikɛl sɛl anemia, we min se dɛn gɛt abnɔmal ɛmoglobin we dɛn kin chenj.

Aw dɛn go analayz dis blɔd sɛmpul na di lab?

Okay, naw wi don tek di blood sample. Wetin kin apin afta dat? Insay di lab, dɛn kin separet dɛn kayn ɛmoglobin ya ɛn no dɛn insay wan we we rili intrestin. Dɛn kɔl dat fɔ yuz ilɛktrik chaj . Di men kayn ɛmoglobin gɛt difrɛn ilɛktrik chaj.

Na dis na aw dis tɛst kin wok:

• Fɔs, dɛn kin pul di rɛd blɔd sɛl dɛn frɔm di blɔd sɛmpul ɛn sɔlv dɛn. Dɛn kin put dis rɛd blɔd sɛl sɛmpul we dɔn sɔlv pan wan spɛshal strip lɛk sɛlulɔz strip .
• Dɔn, dɛn kin put di strip we gɛt di sampul insay wan mashin we dɛn kɔl ilɛktrɔfɔrɛsis chɛmba . Dis mashin de pas ilɛktrik kɔrɛnt tru di sampul.
• Fɔ ansa di ilɛktrik kɔrɛnt, di kayn ɛmoglobin dɛn we gɛt difrɛn ilɛktrik chaj dɛn kin separet frɔm dɛnsɛf ɛn muv along di strip wit difrɛn spid.
• Afta sɔm tɛm, dɛn kayn ɛmoglobin ya we dɛn separet kin apia lɛk difrɛn kɔlɔ band dɛn na di strip.
• Neks, di mɛdikal tɛknishian dɛn kin kɔmpia dɛn tɛst rizɔlt ya wit di rizɔlt fɔ wan nɔmal ɛmoglobin sɛmpul frɔm pɔsin we gɛt wɛlbɔdi.
• If di lɛvɛl fɔ wan patikyula kayn ɛmoglobin bɔku ɔ smɔl pas aw i fɔ gɛt, dat kin bi sayn fɔ se pɔsin gɛt prɔblɛm wit blɔd. Fɔ ɛgzampul, if yu hemoglobin S (HgbS) tayp luk difrɛn frɔm di HgbS we nɔmal pɔsin gɛt, i kin bi sayn fɔ se yu gɛt sikɛl sɛl anemia.

Tink bɔt am dis we, jɔs lɛk we yu trowe ston dɛn we gɛt difrɛn wet na wata we de rɔn, di ston dɛn kin travul difrɛn difrɛn say dɛn dipen pan dɛn wet. Na ya, ilɛktrishɔn de wok lɛk da "strim ɔf wata."

Wetin na di difrɛns bitwin isoɛlektrik fɔs (IEF) ɛn ilɛktrɔfɔrɛsis?

Isoelectric focusing (IEF) na ɔda we we dɛn kin yuz fɔ no di kayn ɛmoglobin dɛn we nɔ de wok. IEF ɛn ilɛktrɔfɔresis ɔl tu de yuz ilɛktrik kɔrɛnt fɔ separet di kayn ɛmoglobin dɛn. Bɔt sɔm tɛknikal difrɛns de bitwin di tu we dɛn. Sɔntɛnde, dɛn kin yuz dɛn tu we ya fɔ no di kayn ɛmoglobin dɛn kɔrɛkt wan.

Aw lɔng i kin tek fɔ mek di ripɔt kam?

Di tɛst kin tek lɛk wan awa fɔ dɔn na di lab. Bɔt i kin tek sɔm dez fɔ mek yu dɔktɔ gɛt di rizɔlt, rivyu dɛn, ɛn ɛksplen to yu. So nɔ ɛkspɛkt di ripɔt wantɛm wantɛm afta di tɛst. Di dɔktɔ go tɛl yu di de we yu nid fɔ kam fɔ tek di ripɔt.

Wetin mi ripɔt min? Aw a go ɔndastand am?

Dis na di tin we impɔtant pas ɔl. Yu ɛmoglobin ilɛktrɔfɔrɛsis ripɔt go list sɔm rɛnj fɔ ɛni kayn ɛmoglobin. Fɔ ɛgzampul, if yu ɛmoglobin F (HgbF) lɛvɛl bɔku pas aw i kin bi, dat kin bi sayn fɔ sɔm kayn thalassemia.

Bɔt, yu nid fɔ mɛmba dis gud gud wan:

Nɔr mek disizhɔn bɔt ɛni sik bay di nɔmba dɛn we de na di ripɔt. Dat na wan pat nɔmɔ pan di diagnosis. Di bɛst pɔsin fɔ ɔndastand gud gud wan wetin de na yu ripɔt ɛn aw i kin afɛkt yu wɛlbɔdi na yu dɔktɔ . I go tink bɔt ɔltin frɔm yu sayn dɛm, ɔda tɛst rizɔlt dɛm, ɛn yu mɛdikal istri fɔ mek yu no di sik kɔrɛkt wan.

If abnɔmal tin dɛn de na mi ripɔt, a fɔ kɔl di dɔktɔ?

Yɛs, na fɔ tru. If yu bin gɛt dis ɛmoglobin ilɛktrɔfɔrɛsis tɛst bikɔs ɔf ɛni sayn (e.g., yu kin taya bɔku tɛm, yu kin pale, yu nɔ kin blo fayn), yu fɔ go to yu dɔktɔ wantɛm wantɛm fɔ tɔk bɔt di rizɔlt fɔ di ripɔt.

Wan ɛmoglobin ilɛktrɔfɔrɛsis tɛst de gi wi wan snɛpsho fɔ di kayn ɛmoglobin we de na yu blɔd da tɛm de. di εmoglobin lεvεl na we fכ no dis imכtant protin we de insay wi rεd bכdi sεl dεm. If yu chenj di lɛvul fɔ wan patikyula kayn ɛmoglobin we nɔrmal, dat kin bi sayn fɔ sho se yu kin gɛt sik.

If yu ɔ yu pikin in tɛst rizɔlt sho se yu gɛt siriɔs sik, i izi fɔ mek yu fil bad ɛn fred jɔs we yu luk di pikchɔ. Ɛspɛshali if na bɔt di wɛlbɔdi fɔ yu yɔŋ pikin ɔ nyu bɔbɔ, i nɔmal fɔ fil se yu at pwɛl. Bɔt tray fɔ luk di big pikchɔ instead fɔ panik. Di bɛst pɔsin fɔ ɛp yu wit dat na yu dɔktɔ. I kin ɛksplen aw dis "pikchɔ" fit yu ɔl wɛl bɔdi ɛn wetin yu nid fɔ du nɛks.

Mɛsej we dɛn kin kɛr go na os

A op se naw yu dɔn ɔndastand gud gud wan bɔt di ɛmoglobin ilɛktrɔfɔrɛsis tɛst we wi tɔk bɔt tide. Na sɔm tin dɛn we yu fɔ mɛmba:

• Ɛmoglobin ilɛktrɔfɔrɛsis na spɛshal blɔd tɛst we de sho di difrɛn kayn ɛmoglobin we de na di blɔd ɛn di kayn we aw dɛn de.
• Dis kin ɛp fɔ no di sik dɛn we gɛt fɔ du wit blɔd lɛk sikɛl sɛl anemia ɛn thalassemia .
• Nyu bɔn pikin in yonDɛn kin du dis bak as pat pan di wɛlbɔdi skrinin.
• Dɛn kin separet di kayn ɛmoglobin dɛn bay we dɛn tek blɔd sɛmpul ɛn yuz ilɛktrik kɔrɛnt .
• Ɔltɛm tɔk to yu dɔktɔ bifo yu tray fɔ ɔndastand di rizɔlt fɔ di ripɔt fɔ yusɛf.
• If di rizɔlt nɔrmal, nɔr panik ɛn fala yu dɔktɔ in instrɔkshɔn. Fɔ no am kwik na di fɔs tin we yu fɔ du fɔ mek yu gɛt di tritmɛnt fayn fayn wan.

Wi op se yu go si se dis infɔmeshɔn go ɛp yu. Stay wit wɛlbɔdi!

` Ɛmoglobin Ilɛktrofɔrɛsis, Ɛmoglobin, Rɛd Blɔd Sɛl, Anemia, Siklɔs Sɛl Anemia, Thalassemia