Yu, ɔ sɔntɛm yu pikin, yu dɔktɔ dɔn tɛl yu fɔ bigin tek wan mɛrɛsin we dɛn kɔl Alpelisib (brand nem: Vijoice). We yu yɛri di nem fɔ dis kayn spɛshal mɛrɛsin, i nɔmal fɔ mek bɔku kwɛstyɔn dɛn kam na yu maynd, lɛk "Wetin dis de du?", "Aw a fɔ tek am?", "Wetin na di tin dɛn we fɔ tek tɛm wit?" So nɔ fred. Tide, wi go tɔk bɔt dis mɛrɛsin we dɛn kɔl Alpelisib insay wan we we rili klia ɛn simpul.
Us kayn mɛrɛsin na Alpelisib?
Fɔ tɔk am simpul wan, Alpelisib na wan mɛrɛsin we de kɔntrol di abnɔmal, nɔ kɔntrol we sɔm sɛl dɛn na di bɔdi de gro. Dɛn kin yuz dis drɔg spɛshal wan fɔ trit wan sik we sɔm pat dɛn na di bɔdi (fɔ ɛgzampul, wan an, wan leg, ɔ sɔm tisu dɛn) kin big pasmak bikɔs ɔf wan muteshon na wan jin we dɛn kɔl PIK3CA . wi kכl dis kכndishכn PIK3CA-rεlatεd כvagrכw spεktrum (PROS) . dis dכg de wok bay we i de blכk di signal path we de mek da abnכmal sεl de gro, so dat i de kכntro di sik.
Yu dɔktɔ kin gi yu dis fɔ ɔda mɛrɛsin dɛn bak, so if yu gɛt ɛni kwɛstyɔn, tɔk to yu dɔktɔ bɔt am.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Fɔ yu sef ɛn fɔ gɛt di bɛst pan di mɛrɛsin, i impɔtant fɔ tɛl yu dɔktɔ dis infɔmeshɔn bifo yu bigin fɔ yuz Alpelisib.
- If yu gɛt dayabitis: Tɛl wi if yu dɔn ɔlrɛdi gɛt dayabitis ɔ yu gɛt ay shuga na yu blɔd.
- Lɔng sik: If yu gɛt ɛni lɔng sik, lɛk asma ɔ nyumonia.
- Alɛji: Mek shɔ se yu tɛl yu dɔktɔ if yu gɛt ɛni alɛji to Alpelisib ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- Bɛlɛ: If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu ivin tink smɔl se yu gɛt bɛlɛ.
- If yu na mama we de gi pikin in bɛlɛ: If yu de gi pikin in bɛlɛ.
We di dɔktɔ no bɔt dɛn tin ya, i go izi fɔ am fɔ plan di tritmɛnt we go fayn fɔ yu.
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
I rili impɔtant fɔ fala di rayt instrɔkshɔn fɔ yuz dis mɛrɛsin.
- Tek di mɛrɛsin jɔs lɛk aw di dɔktɔ tɛl yu fɔ tek am, di sem tɛm ɛvride .
- Nɔ kɔt ɔ chew dis tablɛt. Swɛla di tablɛt ɔl wit wata.
- I bɛtɛ fɔ tek di mɛrɛsin wit it .
- Kɔntinyu fɔ tek di mɛrɛsin te yu dɔktɔ tɛl yu fɔ stɔp. Nɔ stɔp wantɛm wantɛm, ilɛksɛf yu fil fayn.
Wetin fɔ du if di pil at fɔ swɛla?
Sɔm pipul dɛn, mɔ pikin dɛn, kin gɛt prɔblɛm fɔ swɛla pils. If na so i bi, na dis na aw fɔ du am:
1. Put di tablɛt insay glas wit 2-4 ɔns (lɛk 60-120 ml) wata.
2. Afta lɛk 5 minit, krɔs di tablɛt fayn fayn wan wit klin spun ɛn stir am fayn fayn wan te i sɔlv insay di wata.
3. Drink dis miksɔp wantɛm wantɛm.
4. Dɔn, ad 2-3 mɔ tebul spɔnj wata to di sem glas, was dɔŋ ɛni mɛrɛsin we lɛf na di glas, ɛn drink dat. Du dis di we we nɔ go west wan drop pan di mɛrɛsin.
Impɔtant: Dɛn kin gi dis mɛrɛsin bak fɔ pikin dɛn we dɔn pas 2 ia pan sɔm spɛshal kes dɛm. Bɔt na yu dɔktɔ nɔmɔ go disayd bɔt dis. So, if yu de gi pikin dis mɛrɛsin, fala di dɔktɔ in instrɔkshɔn dɛn gud gud wan.
Wetin a go du if a tek bɔku mɛrɛsin (ɔvados)?
If yu tink se yu dɔn tek dis mɛrɛsin tumɔs, nɔ delay. Wantɛm wantɛm kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital . Ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu fɔgɛt fɔ tek wan doz, tek am jɔs lɛk aw yu mɛmba. Bɔt if i nɔ rich 9 awa te yu tek yu nɛks doz we yu mɛmba (i.e., pas 9 awa let), skip di doz we yu mis. Jɔs tek di nɛks doz na di tɛm we dɛn dɔn sɛtul. Nɔ ɛva tek tu doz wan tɛm fɔ mek di doz we yu mis.
Ɔda mɛrɛsin dɛm wae kin miks wit dis mɛrɛsin (Drug Interactions) .
Sɔm mɛrɛsin dɛm wae yu de tek kin intarakt wit Alpelisib ɛn afɛkt in ɛfɛktiv ɔr sayd ɛfɛkt dɛm. So, tɛl yu dɔktɔ if yu de tek ɛni wan pan dɛn mɛrɛsin ya ɔ ɛni ɔda sɔpɔt, vaytamɛn, ɔ ɛbul mɛrɛsin.
- Sɔm mɛrɛsin dɛm wae dɛn kin yuse fɔ ɛpilepsi: Fɔ ɛgzampul, `(Carbamazepine)`, `(Phenobarbital)`, `(Phenytoin)`.
- `Sayklɔspɔrin`
- `Ɛltrombopag`
- `Enzalutamide`
- `Mitotane`
- `Rifampin` (na mɛrɛsin fɔ TB) .
- `St. John’s Wort` (wan ɛbul mɛrɛsin fɔ mek pɔsin gɛt wɛlbɔdi)
- `Sulfasalazin`
- `Warfarin` (na mɛrɛsin we dɛn kin gi fɔ mek blɔd nɔ klɔt)
Dis list nɔ kɔmplit, so i bɛtɛ fɔ mek yu tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
Tin dɛn we yu fɔ tek tɛm wit mɔ we yu de tek di mɛrɛsin
- Yu fɔ chɛk yu dɔktɔ ɔltɛm: Chek wit yu dɔktɔ ɔltɛm fɔ si if yu sik de go bifo ɔr de wɔs. Nɔ skip di blɔd tɛst we nid fɔ du (blɔd wok).
- Bɔrku riakshɔn na dɛn skin: Sɔm pipul kin gɛt siriɔs riakshɔn na dɛn skin ivin sɔm wiks afta dɛn dɔn bigin dis mɛrɛsin.Tɛl yu dɔktɔ wantɛm wantɛm if yu gɛt rash wit di sayn dɛm lɛk fiva ɔ kol. Dɛn rash ya kin tɔn rɛd ɔ pepul, dɔn blista ɛn pul. Ɔ if yu notis se rɛd rɔsh de na yu fes, lip, nɛk, ɔ armpit wit di limf no dɛm we dɔn swel, kɔl yu dɔktɔ wantɛm wantɛm.
- Sivɛri dayarɛa ɛn we yu nɔ gɛt wata na yu bɔdi: Tɛl yu dɔktɔ if yu gɛt bad bad dayarɛa, yu de vɔmit, ɔ yu de swet pasmak . If yu lɔs bɔku wata na yu bɔdi (dehydration) kin denja we yu de tek dis mɛrɛsin.
- Ay blɔd shuga (Hyperglycemia): Dis mɛrɛsin kin mek yu gɛt ay blɔd shuga. Dis risk kin pasmak pan pipul dɛm wae dɔn ɔlrɛdi gɛt dayabitis. Tɛl yu dɔktɔ if yu fil fɔ tɔsti pas aw yu kin tɔsti, yu kin pis bɔku tɛm, yu kin taya pasmak, ɔ yu nɔ kin si fayn .
- Dray mɔt: Yu kin gɛt dray mɔt. Dis kin bi bay tin dɛm lɛk fɔ it gɔm we nɔ gɛt shuga ɛn fɔ drink bɔku wata. Bɔt if di prɔblɛm kɔntinyu ɔ i bad, tɛl yu dɔktɔ.
Wan rili impɔtant wɔnin bɔt bɛlɛ: Nɔ gɛt bɛlɛ ɔltogɛda we yu de tek dis mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp di mɛrɛsin. Man dɛn fɔ avɔyd bak fɔ bɔn pikin we dɛn de tek dis mɛrɛsin ɛn fɔ wan wik afta dɛn dɔn stɔp di mɛrɛsin. Dis mɛrɛsin kin ambɔg di pikin we de na in bɛlɛ bad bad wan. Aks yu dɔktɔ fɔ no mɔ bɔt dis. Dɔn bak, nɔ gi pikin in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp di mɛrɛsin.
Sayd ɛfɛkt dɛn we kin apin bikɔs ɔf mɛrɛsin
| Sayd ɛfɛkt we pɔsin kin gɛt | Diskripshɔn ɛn wetin fɔ du |
|---|---|
| Sayd ɛfɛkt dɛn we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip, tong ɔ trot. |
| Sivɛri dayarɛa | Flatulɛns we nɔ go ebul fɔ stɔp. |
| Di blɔd shuga we bɔku (Hyperglycemia) . | Tɔsti pasmak, pis bɔku tɛm, taya pasmak, yu nɔ de si fayn. |
| Injury na di lɔng | I nɔ izi fɔ blo, kɔf, blɔd blɔd, chɛst pen, fiva. |
| Bɔrku sik dɛn we kin kam pan pɔsin in skin | Rɛd, blista, pil skin (ivin insay di mɔt). |
| Tin dɛm fɔ tɛl yu dɔktɔ if dɛn kɔntinyu ɔr de mɔna yu | |
| Dray skin | Dray skin |
| Ed de at | Ed de at |
| Di ia we de lɔs | Di ia we de lɔs |
| Sɔm na yu mɔt ɔ yu trot | Pen, rɛd, ɔ swel wit sɔri insay di mɔt ɔ trot |
Aw yu kin kip yu mɛrɛsin sef?
- Kip fa frɔm pikin ɛn animal dɛn we yu de mɛn.
- Stɔr am na tɛmpracha bitwin 20 ɛn 25 digri sɛlshiɔs (68-77 Farenheit), we na nɔmal rum tɛmpracha.
- Nɔ yuz mɛrɛsin we dɔn pas.
- We yu de trowe mɛrɛsin we yu nɔ yuz ɔ we dɔn pas, chɛk di lɛbl fɔ si if i sef fɔ trowe. If yu gɛt dawt, aks yu dɔktɔ. If dɛn sef fɔ trowe, pul di pils dɛn na di bɔtul ɛn miks dɛn wit sɔntin lɛk kɔfi grɔn we dɛn dɔn yuz, dɔti, ɔ pusi dɔti, put dɛn insay bag ɔ kɔntena we dɛn tayt tayt, ɛn trowe dɛn na di dɔti.
Mɛsej we dɛn kin kɛr go na os
- Alpelisib na spɛshal mɛrɛsin, so ɔltɛm tek am jɔs lɛk aw yu dɔktɔ tɛl yu, ɛn di rayt tɛm.
- Tɛl yu dɔktɔ bɔt ɛni ɔda mɛrɛsin we yu de tek ɛn ɛni ɔda mɛrɛsin we yu gɛt bifo yu bigin di mɛrɛsin.
- Wach ɔltɛm fɔ si if yu gɛt siriɔs riakshɔn na yu skin (fiva, rash, blista) ɛn sayn dɛm fɔ ay blɔd shuga (we yu tɔsti pasmak, yu de pis bɔku tɛm). Tɛl yu dɔktɔ wantɛm wantɛm if yu notis ɛnitin.
- I rili impɔtant fɔ avɔyd fɔ gɛt bɛlɛ ɔltogɛda we yu de tek dis mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp am.
- Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ ɛva sheb am wit ɔda pipul dɛn.
- If yu gɛt ɛni kwɛstyɔn, wɔri, ɔ dawt bɔt di mɛrɛsin, nɔ gɛs, bɔt tɔk to yu dɔktɔ dairekt wan.
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