Yu dɔktɔ gi yu nyu mɛrɛsin? Dɛn se dɛn kɔl am alfa-blɔka? Sɔntɛm na fɔ yu blɔd prɛshɔn, ɔ if yu na man, fɔ wan kɔndishɔn lɛk prɔstat we dɔn big. Nɔ wɔri, di nem kin tan lɛk se i kɔmplikt smɔl. Tide, wi go tɔk bɔt dis kayn mɛrɛsin insay simpul wɔd, aw i de wok, ɛn wetin yu nid fɔ no.
Fɔ tɔk am simpul wan, wetin na dɛn alfa-blɔk ya?
Alfa-blɔka na wan kayn mɛrɛsin we dɛn kin yuz mɔ fɔ mɛn ay blɔd prɛshɔn , ɔ ay blɔd prɛshɔn. Dɛn kin yuz dɛn bak fɔ sɔm ɔda tin dɛn.
imajin se sכm sכm "rεsεptor" dεm de na di sεl dεm na wi bכdi. I tan lɛk we dɛn lɔk na domɔt. We yu put ki insay, yu kin opin di domɔt. we sכm כmon dεm de tay pan dεn rεsεpכta dεm ya, sכm akshכn dεm de apin. wetin dis mεdisin de du na fכ blכk di "alfa" rεsεpכta dεm fכ sכm tεm. I tan lɛk se yu put sɔntin na di lɔk ɛn mek dɛn nɔ put di ki insay. Dis kin mek sɔm akshɔn dɛn nɔ apin.
Chek fɔ si if ɛni wan pan di mɛrɛsin dɛn we yu dɔktɔ dɔn gi yu gɛt nem dɛn lɛk doxazosin, prazosin, ɔ terazosin. Dis na di kayn alfa-blɔk we dɛn kin gi mɔ.
Tayp dεm fכ Alfa-Rεsεptor dεm na wi bכdi
tu men kayn alfa rεsεpכta dεm de na wi bכdi. E fayn fɔ no smɔl bɔt dis fɔ ɔndastand aw dis mɛrɛsin de woke.
| Di kayn pɔsin we de tek di tin | Di wok we dɛn de du |
|---|---|
| Alfa-1 rεsεptכr | Dɛn tin ya kin de mɔ na wi blɔd vesel, prɔstat, ɛn blad mɔsul dɛn. We dɛn tin ya wok, di blɔd vesel dɛn kin kɔntrakt. Dɔn di prɛshɔn kin go ɔp. di mכsul dεm na di prכstat de tayt bak. |
| Alfa-2 rεsεptכr | Dɛn tin ya kin de mɔ na di bren ɛn di nervɔs sistɛm. Dɛn kin ɛp fɔ mek di nervɔs sistɛm wok fayn ɛn fɔ mek di bɔdi kol. |
We di mɛrɛsin dɛn we de blok di alfa de blok di alfa-1 risepta dɛn, di blɔd vesel dɛn ɛn di mɔsul dɛn na di prɔstat gland kin rilaks . We di blɔd vesel dɛn rilaks, blɔd kin flɔ izi wan, ɛn dis kin mek di blɔd prɛshɔn go dɔŋ. We di mɔsul dɛn na di prɔstat gland rilaks, i kin mek i izi fɔ pis.
Wetin na di kayn Alfa-Blɔka dɛn?
Dɛn kin sheb dɛn mɛrɛsin ya to tu men kayn.
1. Selektiv Alfa-Blɔk dɛn
Dɛn tin ya tan lɛk pɔsin we de snaypa. Dɛn kin jɔs hit di target dairekt wan. Dat min se dis kayn mɛrɛsin de mɔna di alfa-1 rεsεp כta dεm . So, di sayd ɛfɛkt dɛn nɔ bɔku. Sɔm ɛgzampul dɛn na:
- Alfuzosin we dɛn kɔl
- Dɔksazosin we dɛn kɔl
- Prazosin we dɛn kɔl Prazosin
- Silodosin we dɛn kɔl
- Tamsulosin we gɛt di sik
- Terazosin we dɛn kɔl Terazosin
2. Nɔn-sɛlektiv Alfa-Blɔka dɛn
Dɛn tin ya difrɛn smɔl. Dɛn tan lɛk shotgun. dεn de blכk כl tu di alfa-1 εn alfa-2 rεsεpכta dεm. Dis min se dɛn kin gɛt mɔ ifɛkt pan di bɔdi, ɛn dɛn kin gɛt mɔ sayd ɛfɛkt bak . Bikɔs dɛn kin blok di alfa-2 riseptɔ dɛn bak, di amɔnt ɔf norepinephrine, we na wan ɔmon we de mek wi strɛs na wi bɔdi, kin bɔku, we kin mek di at rit mɔ ɛn mek wi nɔ rɛst. Fεnכksibεnzamin εn fεntolamin na εgzampl fכ dis kayn.
Na fɔ blɔd prɛshɔn ɛn prɔstat prɔblɛm nɔmɔ dɛn kin gi dis mɛrɛsin?
Nɔ, dis mɛrɛsin kin fayn bak fɔ sɔm ɔda sik dɛn we pɔsin kin gɛt.
- Benign Prostatic Hyperplasia (BPH): Dis na wan sik we di prɔstat gland kin swel as man dɛn de ol. Dis kin mek i nɔ izi fɔ pis. di alfa-blכka dεm de rilaks di mכsul dεm na di prכstat gland, we de mek di urine fכ fכlכ izi wan.
- Sɔm kayn tɔŋ dɛm: Kɔntrol di tɔŋ dɛm we de mek ɔmon dɛm we pasmak lɛk adrenaline.
- Pɔst-traumatic Stress Disorder (PTSD): Manej di strɛs, mɔ di bad bad drim dɛm, we kin apin afta siriɔs traumatik ivin.
- Raynaud in phenomenon: Na wan sik we di finga ɛn fut finga dɛn kin tɔn pale, blu, ɛn nɔm we dɛn de na kol. Dis mɛrɛsin de ɛp fɔ mek di blɔd vesel dɛn rilaks.
- Kidni Ston: Ɛp smɔl ston dɛn we dɔn stɔp na di ureter, di tiub we de kɛr urine frɔm di kidni to di blad, fɔ pas izi wan.
- Prɔstataytis: Na inflamɛns na di prɔstat gland.
Aw lɔng a nid fɔ tek dis mɛrɛsin?
I dipen pan di mɛrɛsin we dɛn de gi yu dis mɛrɛsin fɔ. Fɔ sik lɛk ay blɔd prɛshɔn ɔ BPH, yu kin nid fɔ tek dis mɛrɛsin fɔ lɔng tɛm . Fɔ sɔm tɛm prɔblɛm lɛk kidni ston, yu kin nid fɔ tek am fɔ shɔt tɛm.I se fɔ yuz nɔmɔ.
Di tin we impɔtant pas ɔl: Nɔ stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm we yu nɔ go to yu dɔktɔ fɔ ɛni rizin . If yu du dat, dat kin mek yu gɛt siriɔs prɔblɛm dɛn. I kin ivin mek yu blɔd prɛshɔn go ɔp wantɛm wantɛm te i denja.
If yu kɔntrol yu blɔd prɛshɔn bay we yu chenj yu layf (ɛksɛsayz, it fayn it), ɔ if yu du ɔpreshɔn fɔ pul yu prɔstat gland, yu dɔktɔ go tɛl yu fɔ stɔp fɔ tek dis mɛrɛsin. Ɔl dis fɔ bi ɔnda dɔktɔ advays nɔmɔ.
Lɛ wi lan bak bɔt di bad tin dɛn we kin apin to wi ɛn di bad tin dɛn we kin apin to wi.
Lɛk ɛni mɛrɛsin, alfa-blɔk kin gɛt sayd ɛfɛkt, bɔt nɔto ɔlman kin gɛt am.
Di sayd ɛfɛkt dɛm we kin apin mɔ (especially selective):
- Diziz ɛn layt ed: Lɔw blɔd prɛshɔn (orthostatic hypotension) kin mek yu nɔ si fayn, mɔ we yu tinap wantɛm wantɛm frɔm we yu sidɔm.
- Fɔs doz ɛfɛkt: Dis filin fɔ mek yu nɔ fil fayn ɛn we yu blɔd prɛshɔn go dɔŋ kin notis mɔ insay di fɔs dez afta yu dɔn bigin fɔ tek di mɛrɛsin.
- Ed de at
- We pɔsin taya
- Priapism: Dis na siriɔs ɛn imejensi kɔndishɔn. Na we di penis erection we de mek yu fil pen fɔ pas 4 awa. If dis apin, yu fɔ go wantɛm wantɛm na di imejensi rum (ETU) na ɔspitul.
If yu tek mɛrɛsin dɛn we nɔ de pik, yu kin gɛt bak at rit we de go ɔp ɛn yu mɔsul dɛn kin shek.
Dis mɛrɛsin kin miks bak wit rɔm, sɔm sitrus jus, ɛn ɔda mɛrɛsin dɛn. So tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek.
Udat nɔ fɔ tek dis mɛrɛsin?
Alfa-blɔk nɔr fayn fɔ pipul dɛm wae gɛt sɔm kayn wɛl bɔdi prɔblɛm.
- If yu de plan fɔ du ɔpreshɔn pan yu katarakt: Dis mɛrɛsin kin afɛkt di pupil, we kin mek di ɔpreshɔn at. So mek shɔ se yu tɛl yu ay dɔktɔ bɔt dis.
- Mama dɛn we de gi pikin dɛn bɛlɛ: Di mɛrɛsin dɛn we dɛn nɔ kin pik nɔ fayn mɔ.
- If yu gɛt histri fɔ Ɔtostatik Haypɔtɛnshɔn: Dis min se if yu kin fil bɔku tɛm we yu tinap we yu sidɔm, dis mɛrɛsin kin mek di sik wɔs.
- If yu de tek mɛrɛsin fɔ erectile dysfunction: Sɔm mɛrɛsin kin riak wit dɛn tin ya ɛn mek yu blɔd prɛshɔn dɔŋ we denja.
- If yu gɛt sik na yu kidni ɔ yu gɛt sik we de mek yu blɔd blɔd go na yu bɔdi:Sɔntɛm di mɛrɛsin dɛn we dɛn nɔ kin pik nɔ fayn.
Wetin dɛn kin du fɔ ridyus di sayd ɛfɛkt wans dɛn dɔn bigin fɔ tek di mɛrɛsin?
Yɛs. Wan impɔtant advays de. If yu dɔktɔ tɛl yu fɔ bigin wan sɛlɛktif alfa-1-blɔka, tek di fɔs pil na nɛt bifo yu go slip.
Bikɔs di "fɔs-doz ifɛkt" na di fɔs tɛm we yu bigin fɔ fil di ifɛkt dɛn we di fɔs doz gɛt. We yu tek di mɛrɛsin bifo yu go slip na nɛt, tin lɛk we yu blɔd prɛshɔn go dɔŋ ɛn diziz go apin we yu de slip, so yu nɔ go fil am lɛk aw yu de fil. Dis na advays we rili impɔtant.
Ustɛm yu fɔ go to dɔktɔ?
If yu sik chenj wantɛm wantɛm, mɔ if dɛn de mek i nɔ izi fɔ yu fɔ du di tin dɛn we yu de du ɛvride, kɔl yu dɔktɔ. Bɔt yu fɔ go to dɔktɔ wantɛm wantɛm if ɛni wan pan dɛn tin ya apin:
| Situeshɔn dɛn we nid fɔ gɛt mɛrɛsin kwik kwik wan | |
|---|---|
| I nɔ kin no natin ɔ i kin fɔdɔm | Faint ɔ pas ɔt |
| Chɛst pen (angina) . | Chɛst de pen |
| I nɔ kin izi fɔ yu fɔ blo | Shot we yu de blo |
| At bit kwik kwik wan ɔ we nɔ de bit ɔltɛm | At bit fast ɔ i nɔ de bit ɔltɛm |
| Priapism (di erekshɔn we de mek pɔsin fil pen we de te pas 4 awa) . | Wan erection we de mek pɔsin fil pen, we de tek 4 awa |
| Di simptom dɛm fɔ wan siriɔs alɛji (anaphylaxis) - e.g. ayv, it, swel, i nɔ izi fɔ swɛla. | Di sayn dɛm fɔ wan siriɔs alɛji |
Na nɔmal tin fɔ fil smɔl fred ɔ wɔri we yu de bigin fɔ tek nyu mɛrɛsin. Alfa-blɔka na wan klas fɔ mɛrɛsin we dɛn kin yuz bɔku bɔku wan ɛn we kin wok fayn fɔ mɛn bɔku sik dɛn. If yu dɔktɔ dɔn gi yu dis mɛrɛsin, tɔk to yu dɔktɔ bɔt ɛnitin we de mɔna yu ɔ kwɛstyɔn we yu gɛt. Dis go ɛp yu fɔ ɔndastand gud gud wan aw fɔ yuz di mɛrɛsin.
Mɛsej we dɛn kin kɛr go na os
- Alfa-blɔka na wan kayn mɛrɛsin we kin mɔs trit ay blɔd prɛshɔn ɛn prɔstat we big pan man dɛn.
- Nɔ ɛva stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm if yu nɔ gɛt dɔktɔ advays. I kin denja.
- We yu bigin fɔ tek di mɛrɛsin, if yu tek di fɔs doz bifo yu go slip, dat kin mek yu nɔ gɛt bɔku sayd ɛfɛkt dɛn lɛk fɔ gɛt diziz ɛn fɔ slip.
- If yu gɛt siriɔs sik lɛk aw yu de fil pen na yu chɛst, yu nɔ de no natin, ɔ yu de blo pen pas 4 awa, go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm.
- I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɛni ɔda mɛrɛsin, vaytamɛn, ɔ sɔpɔtmɛnt we yu de tek.
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