Yu dɔn ɛva notis pɔsin we ol in an dɛn stret, bɔt i kin drɔp wantɛm wantɛm we i nɔ want ɛn flik bak ɔp? I tan lɛk se i tan lɛk bɔtaflay we de flap in wing. Sɔntɛm yusɛf go dɔn ivin ɛkspiriɛns dis. Dis nɔto wan kayn we aw pɔsin kin shek; insay mɛrɛsin, wi kin kɔl dis Asterixis . I nɔto sik insɛf, bɔt na klinik sayn fɔ wan ɔndalayn mɛdikal kɔndishɔn. So, wetin mek dis kin apin, ɛn yu fɔ wɔri? Lɛ wi brok am klia wan ɛn simpul wan wit Nirogi Lanka.
Wetin na Asterixis?
Fɔ tɔk am simpul wan, Asterixis kin apin we wan mɔsul we yu de yuz tranga wan—fɔ ɛgzampul, we yu ol yu an dɛn ɔp—rilaks fɔ shɔt tɛm we yu nɔ want. Dis kin apin bikɔs di signal dɛn we de sɛn frɔm yu bren nɔ de wok fɔ smɔl tɛm.
Tink bɔt am lɛk se yu de push pan wɔl. If yu an mɔsul dɛn fɔ rilaks fɔ smɔl sɛkɔn, yu an go drɔp fɔ go bifo ɛn afta dat i go snap bak na di say we i de. Na dat na di men tin we kin apin wit Asterixis. Fɔ mɛn pipul dɛn, dɛn kin kɔl am bak negatif myoklonus . Insay dis kɔntɛks, "nɛgitiv" nɔ min "bad"; i de tכk bכt di mכsul dεm we de lכs. biכs wan tכpik mכsul twitch (positiv myoclonus) involv fכ du pasmak, wi kכl dis di כpכsite— wan sכm tεm "dכp" כ lכs fכ aktiviti.
Dis kכndyushכn kin kכmכt frכm dayrekt εshyu dεm insay di bren, כ i kin bi sεkכnd sεmtin fכ di sistεm prכblεm, lεk di liva כ kidni dεm we de afekt di bren fכ wok.
Aw dɛn kin no am?
Asterixis kin afɛkt ɔl tu di say dɛm na di bɔdi, pan ɔl we wan wan tɛm i kin bi asymmetrical. Bɔrku tɛm, i kin kam wit ɔda sayn dɛm lɛk fɔ slip, fɔ kɔnfyus yu maynd, ɛn fɔ nɔr de tink bɔt tɛm ɔr ples .
Yu dɔktɔ go mɔs yuz wan pan dɛn tu klinik we ya fɔ chɛk if i gɛt am:
1. Di we aw yu de pul yu an: Yu dɔktɔ go aks yu fɔ es yu an dɛn fɔ go bifo wit yu an dɛn we de luk na do, lɛk se yu de push pan wɔl we yu nɔ de si, wit yu finga dɛn we de spre big big wan. if, we yu de ol dis posishכn fכ lεk 30 sekכnd, yu an dεm we yu nכ want fכ "flap" dכn εn snap bak כp, i de sho se Asterxis de.
2. Grip we: Insay dis tɛst, yu dɔktɔ go aks yu fɔ grip dɛn an tayt tayt wan. Dɛn go ebul fɔ fil if yu grip trɛnk de shek ɔ "giv way" fɔ smɔl tɛm, we na klinik mak fɔ di kɔndishɔn.
I impɔtant fɔ mɛmba se we dɛn de du klinik ɛgzamin, Asterixis nɔ kin sho wantɛm wantɛm. Yu dɔktɔ kin aks yu fɔ kip di pozishɔn fɔ wan minit ɔ mɔ fɔ mek shɔ se yu wach yu kɔrɛkt wan.
Wetin mek Asterixis kin apin, ɛn wetin na di men tin we kin mek i gɛt dis sik?
Asterixis kin kam bikɔs ɔf sɔm tin dɛn, mɔ we di impɔtant ɔgan dɛn na yu bɔdi nɔ de wok fayn. Lɛ wi luk dɛn ɔndalayn kɔz.
| Kayn | Fɔ ɛksplen |
|---|---|
| Liva ɛn Kidni Isyu dɛn | Yu liva ɛn kidni dɛn de filta di pɔyzin dɛn we de kɔmɔt na yu blɔd. We dɛn ɔgan ya nɔ wok, pɔyzin kin gɛda. Bikɔs yu bren kin rili sɛnsitiv, dɛn pɔyzin ya kin mek yu bren nɔ wok fayn, ɛn dis kin mek yu gɛt Asterixis. Kɔndishɔn lɛk wae yu liva nɔr de woke fayn, yu kidni nɔr de woke fayn, ɛn sirosis na tin dɛm wae kin mek yu gɛt dis sik. |
| Injuri dɛn na di Bren | Injuri ɔ ɔndalayn mɛdikal kɔndishɔn kin mek lɛsin na sɔm patikyula say dɛn na di bren we de kɔntrol di kɔdineshɔn we di mɔsul dɛn de wok togɛda. Insay dɛn kayn tin ya, yu kin si dis sayn na wan say nɔmɔ na di bɔdi. |
| Ɔda Mɛdikal Kɔndishɔn dɛn | I nɔ balans na di blɔd kemistri kin bi bak wan rizin. Sɔm ɛgzampul dɛn na haypoglycemia (lɔ blɔd shuga), haypokalemia (lɔ potassium), haypomagnesemia (lɔ magnesium), at we nɔ de wok fayn, ɛn we i nɔ de blo fayn. Apat frɔm dat, di tin dɛn we kin apin to pɔsin in jɛnɛtiks lɛk di sik we dɛn kɔl Wilson, usay kɔpa kin gɛda na di bɔdi, kin mek i gɛt dis. |
Asterixis we dɛn kin gi bikɔs ɔf mɛrɛsin dɛn
Wan wan tɛm, Asterixis kin bi wan tɛmporari sayd ɛfɛkt fɔ sɔm mɛrɛsin dɛn. Di risk kin pasmak if yu gɛt liva ɔ kidni prɔblɛm we bin dɔn de bifo.
Sɔm ɛgzampul dɛn we dɛn kin yuz na:
- di mεdikeshכn dεm we de fכ mek yu sik: Patikul fεnytoin, we dεn kin kכl "phenytoin flap." Ɔda drɔgs lɛk gabapentin, valproate, ɛn carbamazepine kin mek am bak.
- Barbiturates we dɛn kin yuz
- Benzodiazepin dɛn we dɛn kin yuz
- Sɔm antibayɔtik dɛn
- Litiɔm (wan tin we de mek pɔsin fil fayn) .
- Metoclopramide (wan mɛrɛsin we de mek pɔsin nɔ fil fayn) .
Aw dɛn kin trit dis?
Nɔr patikyula mɛrɛsin nɔr de jɔs fɔ Asterixis insɛf. Dɔktɔ dɛn kin pe atɛnshɔn fɔ no di rizin we mek pɔsin gɛt dis sik ɛn fɔ trit da sik de.
Fɔ ɛgzampul:
- If na sik na di liva, wi kin manej di liva kɔndishɔn.
- If na di rεnal εshyu, wi de adrεs di kidni fכnshכn.
- If na wan mɛrɛsin mek yu du di bad tin, yu dɔktɔ go ajɔst di doz ɔ chenj yu to ɔda tritmɛnt.
So, if yu gɛt Asterixis, di tin we impɔtant pas ɔl na fɔ gɛt kɔrɛkt diagnosis fɔ bigin di rayt tritmɛnt. Dis nɔr kin ɛva bi wan sik wae yu fɔ tray fɔ trit na os.
Wetin na di prɔblɛm dɛn we kin apin we pɔsin lɛf am we dɛn nɔ trit am?
Di big big risk fɔ ignore Asterixis na fɔ nɔ adrɛs di siriɔs mɛdikal kɔndishɔn we de kɔz am. Dɛn sik ya we de ɔnda dis sik kin mek pɔsin in layf de pan denja. If yu nɔ gɛt tritmɛnt, yu kin gɛt prɔblɛm wit yu nyurolɔjik damej fɔ ɔltɛm, ɛn dis kin afɛkt yu kɔgnishɔn, waka, ɛn fayn fayn motoka skil dɛm.
If Asterixis afɛkt yu leg ɔ yu trɔnk, i kin mek yu fɔdɔm wantɛm wantɛm ɛn yu kin wund bad bad wan afta dat.
Ustɛm yu fɔ go to dɔktɔ wantɛm wantɛm?
If yu sɔspɛkt se yu de gɛt sayn dɛm fɔ Asterix, yu fɔ go to dɔktɔ kwik kwik wan.
Dɔn bak, duya trit dɛn tin ya as mɛdikal imejensi :
- If Asterxis de kam wit kɔnfyushɔn.
- If yu gɛt prɔblɛm wit yu maynd, lɛk we yu nɔ no wetin de arawnd yu, di tɛm, ɔ udat yu bi.
- If yu sho ɔda chenj dɛn we de apin to yu maynd wantɛm wantɛm.
Dɛn simptom ya de sho se i gɛt big impak pan di wok we di bren de du. If dɛn kayn tin ya apin, duya go na di imejensi dipatmɛnt we de nia yu wantɛm wantɛm.
Mɛsej we dɛn kin kɛr go na os
👩🏽 ⚕️ Kwɛstyɔn dɛn we dɛn kin aks bɔku tɛm (FAQs)
💬 Wetin na di spɛshal mɛrɛsin we dɛn kin yuz fɔ mek Macitentan (Opsumit)?
Dis na tritmɛnt we dɛn rili spɛshal. Dɛn kin yuz am fɔ trit ‘Pulmonary Arterial Hypertension (PAH),’ na siriɔs sik we di blɔd vesel dɛn we de kɛr blɔd frɔm yu at to yu lɔng kin smɔl ɛn stif, we kin mek yu gɛt ay blɔd prɛshɔn we denja. We dis mɛrɛsin de wok lɛk ‘Endothelin Receptor Antagonist,’ dɛn mek am fɔ slo di sik ɛn mek yu liv lɔng.
💬 Aw Macitentan de ɛp we di pulmonari blɔd vesel dɛn de kam stɔp?
wan bad tin na yu bכdi we dεn kכl ‘Endothelin-1’ de mek dεn blכd vεsul dεm ya sכmtεm sכmtεm sכmtεm sכmtεm sכmtεm sכmtεm (stiffening). we dis mεdikeshכn go insay yu bכdi, i de blכk di rεsεpכta dεm (ETA εn ETB - dual block) we εndotelin-1 de yuz fכ mek dεn pwεl. apat frכm dat, di mεdisin de go insay di lכng tisu fכ εp fכ mek di vessel wכl dεm nכ tik mכr.
💬 Wetin na di krichɔ ‘Blak Bɔks Wɔnin’ we a fɔ no bɔt bifo a tek Opsumit?
Di wɔnin we siriɔs pas ɔl na dat, dɛn nɔ fɔ tek dis mɛrɛsin strikt wan we uman gɛt bɛlɛ; i kin mek di pikin bɔn bad bad wan ɔ i kin mek di pikin day. Uman dɛn fɔ fala sɔm patikyula REMS sefty program dɛn. pan tap dat, pan man dεm, dεn no se dis mεdikeshכn de mek di sεl dεm dכn dכn εn i kin mek dεn nכ bכn pikin. Sɔm pasɛnt dɛn kin gɛt bak big big anemia (we di ɛmoglobin lɛvɛl smɔl).
