We wi tink bɔt asma, bɔku pan wi kin tink bɔt wan tin we dɛn kin yuz fɔ blo. Infakt, fɔ bɔku pipul dɛn, wan tin we dɛn kin yuz fɔ blo kin ɛp dɛn fɔ kɔntrol dɛn asma. Bɔt sɔntɛnde, mɔ fɔ di wan dɛn we gɛt asma we kin tranga smɔl, tɛm kin de we i nɔ kin izi fɔ yuz di inhala kɔrɛkt wan. I kin at fɔ blo ɛn i kin taya. So tide wi go tɔk bɔt wan nyu, advans tritmɛnt we dɛn dɔn introduks fɔ kɔntrol dɛn kayn bad bad asma kɔndishɔn ya. Dɛn kɔl am Bayolojikal Tɛrapi.
Fɔ tɔk am simpul wan, wetin na Bayolojikal Tɛrapi?
Dis na nyu tritmɛnt fɔ siriɔs asma. Di inhala we wi kin yuz kin mek di mɔsul dɛn we de rawnd di say dɛn we di briz de blo rilaks, ɛn dis kin mek i izi fɔ wi fɔ blo. Bɔt dis biyolojikal tritmɛnt difrɛn smɔl.
Imajin se smɔl tin dɛn de insay wi bɔdi we de mek wi gɛt asma, dat na, inflamɛns na di say dɛn we wi de blo. Dɛn kɔl dɛn tin ya antibodi, sɛl, ɔ mɔlyul . Bayolojikal tritmɛnt de spɛshal wan fɔ tɔch ɛn blok di akshɔn fɔ dɛn tin dɛn we de mek pɔsin gɛt asma. I tan lɛk fɔ fɛn di rut fɔ di prɔblɛm ɛn sɔlv am.
Dis tritmɛnt de ridyus di frɛkuɛns we asma kin gɛt, i kin mek dɛn gɛt bɛtɛ layf, ɛn fɔ sɔm pipul dɛn, i kin ivin mek dɛn lɔng fɔ wok fayn to sɔm mak.
Aw dɛn kin gi dis mɛrɛsin to di bɔdi?
Dɛn nɔ kin tek bayolojikal tɛrapi as pil. Dɛn gi am tu men we dɛn:
1. As injεkshכn: Dis na injεkshכn כnda di skin. We wi de tɔk bɔt mɛrɛsin, dɛn kin kɔl am injɛkshɔn we dɛn kin put ɔnda di bɔdi .
2. Bay we yu gi am na vein: Jɔs lɛk aw yu gi salin, dɛn kin gi di mɛrɛsin insay di bɔdi tru kanula. Dɛn kɔl dis infushɔn we dɛn kin put insay di bɛlɛ (IV) .
Di impɔtant tin na dat, bayolojikal tɛrapi nɔto tritmɛnt fɔ insɛf. Yu fɔ yuz am wit ɔda asma mɛrɛsin dɛn we yu dɔn ɔlrɛdi de tek.
Dis min se yu go nid fɔ kɔntinyu fɔ tek di mɛrɛsin dɛn we yu dɔktɔ dɔn tɛl yu, lɛk:
- Alɛji mɛrɛsin: Dɛn tin ya kin bi kɔtikosterɔyd , antihistamin , ɛn antilyukotriene mɛrɛsin (lɛk montelukast ).
- Alɛji shot: Dɛn kin kɔl am bak immunotherapy , dɛn tin ya kin ridyus di alɛji simptom dɛm as tɛm de go.
- Asma inhala: Ɛni inhala we dɛn gi yu fɔ kɔntrol yu siriɔs asma fɔ kɔntinyu wit dis tritmɛnt.
Udat dis tritmɛnt rili fayn fɔ?
Dɛn nɔ kin gi bayolojikal tɛrapi to ɔl di wan dɛn we gɛt asma. Yu dɔktɔ go tink bɔt sɔm tin dɛn bifo i tɛl yu bɔt dis tritmɛnt. Si if yu dɔn ɛkspiriɛns ɛni wan pan dɛn tin ya.
- If dɛn nɔ ebul fɔ kɔntrol yu sik dɛn pan ɔl we yu de yuz di mɛrɛsin we dɛn dɔn gi yu fɔ gɛt asma, mɔ di wan we yu de inhala, kɔrɛkt wan .
- If yu gɛt bɔku bɔku tin dɛn na yu blɔd ripɔt , mɔ di eosinophils ( wan kayn wayt blɔd sɛl we de mek yu swel na di lɔng) ɔ di ay levul fɔ alɛrjens (immunoglobulin E ɔ IgE) .
- If yu no wetin kin mek yu gɛt asma ɛn tray fɔ avɔyd am, bɔt yu sayn dɛn de kɔntinyu fɔ de .
- If yu wek midul nɛt bikɔs i nɔ izi fɔ yu fɔ blo .
- If yu fɔ yuz yu rɛskɔ inhala pas tu tɛm insay di wik.
- If yu fɔ yuz mɛrɛsin lɛk kɔtikosterɔyd fɔ ridyus di swel na di say we yu de blo pas tu tɛm insay di ia we yu asma de wɔs.
- If yu fɔ go na di Imejɛnsi Dipatmɛnt (ETU) pas tu tɛm insay di ia bikɔs ɔf asma simptom.
- If yu dɔn gɛt fɔ de na ɔspitul ɛn gɛt tritmɛnt bikɔs ɔf asma.
If yu gɛt dis sik, i rili impɔtant fɔ tɔk to yu dɔktɔ bɔt if bayolojikal tritmɛnt fayn fɔ yu.
Wetin na di kayn bayolojikal mɛrɛsin wae dɛn kin yuse fɔ gɛt asma?
Bɔku kayn bayolojikal drɔgs de we ɛjɛnshi dɛm lɛk di U.S. Food and Drug Administration (FDA) dɔn gri fɔ. Ɛni wan pan dɛn de wok difrɛn we smɔl. Lɛ wi tek wan luk pan wetin dɛn bi.
| Nem fɔ di mɛrɛsin (brand nem) . | Aw i de wok ɛn udat i fayn fɔ? | Aw fɔ gi | Kɔmɔn sayd ɛfɛkt dɛn |
|---|---|---|---|
| Omalizumab we dɛn kɔl Omalizumab (Xolair®) we dɛn kɔl | I de trit asma we pɔsin kin gɛt we i gɛt alɛji. Blɔk di antibodi we de mek di alɛji rispɔns. I fayn fɔ pipul dɛn we gɛt alɛji to dɔst mit, animal dɛn we dɛn kin mɛn, kɔkrɔs, mold, ɛn ɔda tin dɛn. | 1 ɔ 2 injɛkshɔn ɛvri 2 to 4 wik. Fɔs, dɛn kin gi dɛn ɔnda dɔktɔ in sɔpɔtishɔn, dɔn sɔm kin gɛt dɛn na os. | Mɔsul pen, jɔyn pen, taya, pen ɔ swel na di say we dɛn injɛkshɔn. |
| Mepolizumab we dɛn kɔl Mepolizumab (Nucala®) we dɛn kɔl | I de trit eosinophilic asma. i de blכk wan tin we dεn kכl IL5 we de akt pan di eosinofil dεm na di bכdi. | Wan injɛkshɔn ɛvri 4 wik. Yu kin tek am na os. | Ed pen, pen ɔ swel na di say we dɛn injekt, bak pen, wik, taya. |
| Reslizumab we dɛn kɔl Reslizumab (Cinqair®) we dɛn kɔl | Dis kin trit eosinophilic asma bak. Lɛk mepolizumab, i de blok (IL5). | Dɛn kin gi am as IV infushɔn ɛvri 4 wik. I nɔ kin tek wan awa. Fɔs, dɛn nid fɔ gɛt dɔktɔ fɔ kia fɔ dɛn. | Trot we de at, pen na di mɔsul dɛn. |
| Benralizumab we dɛn kin yuz (Fasenra®) we dɛn kɔl | I de trit eosinophilic asma. i de ridyus di nכmba fכ di eosinofil dεm na di bכdi. | Dɛn kin gi di fɔs 3 dos dɛn ɛvri 4 wik, dɔn ɛvri 8 wik. | Ed we de at, trot we de at. |
| Dupilumab we gɛt di sik (Dupixent®) we dɛn kɔl | I de trit eosinophilic asma. Blɔk ɔda tin dɛn we de mek di bɔdi inflamɛns. | Wan injɛkshɔn ɛvri 2 wik. | Trot we de at, pen ɔ swel na di say we dɛn injekt, i de mek di wayt blɔd sɛl dɛn bɔku. |
| Tezepelumab we dɛn kɔl Tezepelumab (Tezspire®) we dɛn kɔl | Wan nyu biyolojikal drɔg fɔ asma. I de trit siriɔs asma bay we i de ridyus di inflamɛns. | Wan injɛkshɔn ɛvri 4 wik. | Trot de at, bak-ak, jɔyn pen. |
Ɔda kwɛstyɔn dɛn we yu kin gɛt bɔt dis tritmɛnt
Na nɔmal tin fɔ mek bɔku kwɛstyɔn dɛn kam na yu maynd we yu de tɔk bɔt nyu tritmɛnt lɛk dis. Lɛ wi luk di ansa dɛn.
Aw lɔng di tritmɛnt kin tek?
So fa, no definitiv rεkomεndεshכn nɔr de fɔ aw lɔng dis tritmεnt fɔ tek. I kin tek at le 4 mɔnt fɔ no if i de gi yu rilif frɔm yu asma simptom dɛm. So, dɛn kin tek am se na tritmɛnt fɔ lɔng tɛm.
Wetin na di bɛst bayolojikal mɛrɛsin?
I nɔ pɔsibul fɔ se wan mɛrɛsin bɛtɛ pas ɔda wan. No risach nɔr de fɔ kɔmpia dɛn mɛrɛsin ya wit dɛnsɛf. Yu dɔktɔ go disayd us mɛrɛsin go fayn fɔ yu. I go tink bɔt bɔku tin dɛn, lɛk aw yu de chɛk aw yu de blo, aw yu de tɛst yu blɔd, ɛn di kayn asma we yu gɛt.
A nid fɔ kɔntinyu fɔ yuz di inhala?
Yɛs! Rili. Dis rili impɔtant. Ivin afta yu dɔn stat bayolojikal tɛrapi, nɔ ɛva stɔp fɔ yuz yu inhala ɛn ɔda mɛrɛsin dɛn fɔ asma. If dɛn dɔn kɔntrol yu asma fayn fayn wan, yu dɔktɔ go ebul fɔ ridyus di doz we yu de yuz fɔ inhala as tɛm de go. Bɔt na yu disayd fɔ disayd fɔ du dat.
Wetin na di bɛnifit dɛn we bayolojikal tritmɛnt dɛn kin gi?
Di men bɛnifit fɔ dis tritmɛnt na fɔ ridyus di swel na di aywe ɛn kɔntrol di asma simptom dɛm. Apat frɔm dat, bɔku ɔda bɛnifit dɛn de:
- Yu go ebul fɔ du nɔmal tin dɛn fɔ du ɛn ɛksesaiz .
- As di asma de wɔs, di frɛkuɛns fɔ rɔn to di ETU de go dɔŋ.
- Di nid fɔ ɔ di doz fɔ alɛji mɛrɛsin kin ridyus.
- A kin slip fayn bikɔs a nɔ kin wek na nɛt bikɔs i nɔ kin izi fɔ mi fɔ blo.
- Di nɔmba fɔ di de dɛn we yu nɔ de go skul ɔ wok bikɔs ɔf asma go go dɔŋ.
Ɛni prɔblɛm de wit dis tritmɛnt?
Jɛnɛral wan, bayolojikal tɛrapi rili sef. Bɔt lɛk ɔl di mɛrɛsin dɛn, sɔm tin dɛn de we kin mek pɔsin gɛt prɔblɛm ɛn sɔm bad bad tin dɛn we kin apin to am.
- Sivɛri alɛji: Na smɔl tɛm nɔmɔ, sɔm pipul dɛn kin gɛt siriɔs alɛji fɔ dis mɛrɛsin. I kin mek yu skin rash, it, ayv, ɛn sɔntɛnde wan sik we kin mek yu layf de pan denja we dɛn kɔl anafylaksis . Bɔt nɔ panik. Dis na di rizin we mek dɔktɔ dɛn go de wach yu fɔ lɛk tu awa so afta dɛn dɔn gi yu di mɛrɛsin.
- Di risk fɔ gɛt parasayt infɛkshɔn kin bɔku: Bayolojikal mɛrɛsin, mɔ di wan dɛn we de ridyus di nɔmba fɔ di eosinophils na di blɔd, kin mek di risk fɔ gɛt parasayt infɛkshɔn go ɔp. Dɛn eosinofil ya na sɛl dɛn we de ɛp wi imyun sistɛm fɔ fɛt parasayt dɛn, mɔ di ɛlmint dɛn .
- Asma de wɔs if dɛn stɔp di tritmɛnt: If yu stɔp bayolojikal tritmɛnt wantɛm wantɛm, chans de fɔ mek yu asma simptom dɛn wɔs pas aw i bin de bifo.
Ustɛm yu nid fɔ tɔk to yu dɔktɔ?
Mek shɔ se yu tɔk to yu dɔktɔ pan dɛn kayn tin ya.
- If yu asma simptom nɔr de bɛtɛ ɔr tan lɛk se i de wɔs afta sɔm mɔnt wae yu dɔn trit yu.
- If nyu alɛji simptom dɛm (lɛk skin rash, it) bigin fɔ apia.
- If yu mis di de we yu fɔ tek yu mɛrɛsin ɔ nid fɔ chenj am.
- If yu gɛt ɛni ɔda kwɛstyɔn ɔr dawt bɔt dis tritmɛnt.
Usay a go gɛt dis tritmɛnt? Yu tink se inshɔrans de kɔba am?
Dɔktɔ we spɛshal pan asma go disayd if bayolojikal tritmɛnt fayn fɔ yu. I go rivyu yu sik dɛn, di mɛrɛsin dɛn we yu de tek naw, ɛn di blɔd tɛst rizɔlt. Dɛn kin gi dis tritmɛnt na spɛshal pɔsin in ɔfis ɔ na spɛshal yunit (infusion center) na ɔspitul.
Dis tritmɛnt kin rili dia, so tɔk to yu dɔktɔ fɔ si if yu inshɔrans go kɔba am. I kin ɛp yu fɔ mek shɔ se i tɔk to yu inshɔrans kɔmni. Sɔm famasi kɔmni dɛn kin gi program dɛn bak fɔ ɛp pipul dɛn we gɛt dis tritmɛnt.
Mɛsej we dɛn kin kɛr go na os
- Bayolojikal tɛrapi na wan advans tritmɛnt fɔ siriɔs asma we at fɔ kɔntrol wit kɔmɔn mɛrɛsin.
- Dis nɔ de ɛva bi tin fɔ tek ples fɔ yu inhala. Yu fɔ kɔntinyu fɔ yuz yu inhala.
- I kin tek sɔm mɔnt fɔ si di rizɔlt fɔ di tritmɛnt, so peshɛnt.
- Na yu spɛshal pɔsin nɔmɔ go disayd us bayolojikal mɛrɛsin we bɛtɛ fɔ yu.
- Bifo yu bigin dis tritmɛnt, mek shɔ se yu tɔk to yu dɔktɔ bɔt di bɛnifit dɛn ɛn di bad tin dɛn we kin apin to yu.
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