Lɛ wi lan bɔt dis kɔmbayn tri mɛrɛsin (Carbidopa; Levodopa; Entacapone) we dɛn kin yuz fɔ sik we dɛn kɔl Pakinsin.

Yu ɔ sɔmbɔdi na yu famili gɛt dis sik we dɛn kɔl Parkinson? If na so, yu dɔktɔ go dɔn gi yu wan pil we dɛn mek bay we dɛn jɔyn dɛn tri mɛrɛsin ya. Pan ɔl we di nem fɔ dis mɛrɛsin kin tan lɛk se i kɔmplikt smɔl, we yu dɔn ɔndastand aw i de wok, i kin rili simpul. Tide, lɛ wi tɔk bɔt dis mɛrɛsin, wetin i de du, ɛn wetin yu nid fɔ tek tɛm wit, insay padi ɛn simpul we.

Wetin kin apin we dɛn put dɛn tri mɛrɛsin ya togɛda?

Fɔ tɔk am simpul wan, dis na tri mɛrɛsin dɛn we dɛn jɔyn togɛda: Carbidopa, Levodopa, ɛn Entacapone . Di men hiro fɔ dis pil na Levodopa. Pakinsin sik kin kam bikɔs di kεmikכl ‘Dopamine’ na wi bren de dכn. Di mɛrɛsin we dɛn kɔl Levodopa de wok bay we i de go na di bren ɛn ɛp fɔ bil bak dis dopamin we dɔn go dɔŋ.

So wetin kin apin to di ɔda tu drɔgs dɛn? Imajin se Levodopa na pɔsin we de kɛr impɔtant mɛsej.

• Carbidopa tan lɛk bɔdi gad we de protɛkt di pɔsin frɔm prɔblɛm dɛn we de along di rod (frɔm di drɔg we de brok dɔŋ na ɔda pat dɛn na di bɔdi bifo i rich na di bren).
• Entacapone tan lɛk ɔda ɛlda we de mek di bɔdi gad in wok strɔng ɛn alaw Levodopa fɔ wok fɔ lɔng tɛm ɛn fayn fayn wan.

We dɛn tri ya kam togɛda, dɛn kin ɛp fɔ kɔntrol di sik dɛn we de kam wit Pakinson (lɛk fɔ shek, shek, ɛn fɔ waka sloslo).

Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin

I rili impɔtant fɔ mek yu dɔktɔ no yu kɔmplit mɛdikal histri bifo i gi yu dis mɛrɛsin. Dis na bikɔs wi nid fɔ rili tek tɛm we wi de yuz dis mɛrɛsin wit sɔm kayn mɛrɛsin. If yu gɛt ɛni wan pan di sik dɛn we de dɔŋ ya, mek shɔ se yu tɛl yu dɔktɔ bɔt am.

Aw yu kin yuz dis mɛrɛsin?

• Swɛla di pil wit wan glas wata. Tek am jɔs lɛk aw yu dɔktɔ tɛl yu fɔ tek am, di rayt tɛm.
• Di tin we impɔtant pas ɔl: Nɔ brok, krɔs, ɔ chew di tablɛt. Swɛla am ɔl.
• Tek tɛm wit it: Yu kin tek dis mɛrɛsin wit it ɔ yu nɔ it am. Bɔt, tek tɛm we yu de tek di mɛrɛsin.Nɔ it tin dɛn we gɛt bɔku fat, kalori, ɛn prɔtin (lɛk mit, fish, eg, ɛn tin dɛn we dɛn mek wit milk) , bikɔs dɛn it ya kin mek yu nɔ tek bɔku Levodopa. Tɔk to yu dɔktɔ bɔt di it we yu de it.
• Nɔ mis wan doz: Tek yu mɛrɛsin di rayt tɛm. Nɔ tek pas di doz we dɛn tɛl yu fɔ tek ɔ stɔp fɔ tek am wantɛm wantɛm we yu nɔ gɛt yu dɔktɔ in advays. If yu du dat, dat kin mek yu gɛt siriɔs prɔblɛm dɛn.
• If yu mis wan doz: Tek di doz we yu mis as yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek di nɛks doz, skip di doz we yu mis ɛn tek di nɛks pil di tɛm we yu dɔn sɛtul. Nɔ ɛva tek tu dos di sem tɛm.

Ɔda tin dɛm wae kin miks wit dis mɛrɛsin

I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn, ɔyl, ɛn sɔpɔtmɛnt), bikɔs sɔm mɛrɛsin dɛn kin miks wit dis wan.

Na mɔtalman, MAOI (Monoamine Oxidase Inhibitors) mɛrɛsin fɔ mental sik (e.g. Marplan, Nardil, Parnate) nɔ fɔ ɛva tek wit dis mɛrɛsin.

Apat frɔm dat, dis mɛrɛsin kin wok wit dɛn tin ya:

• Rum
• Ayɔn sɔpɔtmɛnt - If yu de tek ayɔn sɔpɔtmɛnt, tek am 2 awa bifo ɔ afta yu tek dis mɛrɛsin.
• Sɔm mɛrɛsin fɔ ay blɔd prɛshɔn
• Mɛrɛsin fɔ mental sik, wɔri, ɛn slip
• Sɔm antibayɔtiks (e.g. ampicillin, ɛrythromycin, rifampin) .
• Nakotik mɛrɛsin fɔ pen
• Warfarin (na mɛrɛsin we dɛn kin yuz fɔ mek blɔd nɔ klin) .

Dis list nɔ kɔmplit, so tɛl yu dɔktɔ bɔt ɔltin we yu de tek.

Speshal pɔynt dɛn we yu fɔ tink bɔt we yu de tek di mɛrɛsin

Fɔ slip ɛn slip wantɛm wantɛm

Dis mɛrɛsin kin mek yu fil lɛk se yu de slip ɔ yu ed de tɔn. Sɔntɛnde, if yu nɔ wɔn yu , yu kin slip we yu de drayv ɔ tɔk. So, nɔ drayv ɔ yuz mashin te yu no aw dis mɛrɛsin de afɛkt yu. Ɛspɛshali if yu dɔn ol, nɔ grap kwik kwik wan we yu sidɔm ɔ tinap. Dis kin mek yu nɔ gɛt diziz ɛn fɔdɔm.

Di tin dɛn we kin mek pɔsin want fɔ du sɔntin ɛn di we aw i kin biev we nɔ kɔmɔn

Na smɔl tɛm nɔmɔ, dɛn dɔn ripɔt se sɔm pipul dɛn we de tek dis mɛrɛsin kin gɛt tin dɛn we nɔ kɔmɔn. Fɔ ɛgzampul, dɛn kin rili want fɔ ple gem, du mami ɛn dadi biznɛs, spɛn mɔni we nɔ nid fɔ du, ɔ it pasmak. If yu ɔ yu famili notis ɛni wan pan dɛn chenj ya, tɛl yu dɔktɔ wantɛm wantɛm.

‘Wearing-off’ ɛn ‘On-Off’ ifɛkt

Sɔmtɛm, as di nɛks doz fɔ di mɛrɛsin de kam nia, e kin fil lɛk se di mɛrɛsin nɔr de woke fayn ɛn yu Pakinsin sik de kam bak. Dɛn kɔl dis di ‘wearing-off’ ifɛkt. Ɔda tɛm, i kin fil lɛk se di mɛrɛsin nɔ de wok atɔl (wan ‘ɔf’ tɛm), ɛn afta dat i kin bigin fɔ wok bak afta sɔm tɛm (wan ‘ɔn’ tɛm). If dis apin to yu, tɛl yu dɔktɔ. I kin ebul fɔ ajɔst yu doz.

Chenj in kɔlɔ na di urine ɛn swet

Dis mɛrɛsin kin tɔn yu urine, saliva, ɔ swet dak brawn, rɛd, ɔ blak. Dis nɔto sɔntin we wi fɔ wɔri bɔt. Bɔt, tek tɛm bikɔs i kin mek klos dɔti.

Tek kia ɔf yu skin.

We yu de tek dis mɛrɛsin, chɛk yu skin ɔltɛm fɔ si if yu gɛt chenj dɛn na di mɔl dɛn we yu dɔn gɛt ɔ if nyu mɔl dɛn de apia. Tɛl yu dɔktɔ if yu notis ɛni chenj.

Us sayd ɛfɛkt dɛn we a go gɛt?

Lɛk ɛni mɛrɛsin, dis wan kin gɛt sɔm bad bad tin dɛn. Bɔku pan dɛn nɔ siriɔs. Bɔt sɔm tin dɛn de we wi nid fɔ no bɔt.