If pɔsin na yu famili, sɔntɛm yu mama, papa, grani ɔ anti we yu lɛk, gɛt Alzaima sik, wi no aw i kin tranga. Wɔd nɔ go ebul fɔ tɔk bɔt aw yu de fil bad ɛn nɔ ebul fɔ ɛp yu as yu de mɛmba smɔl smɔl ɛn i nɔ izi fɔ du di wok dɛn we yu de du ɛvride. Pan ɔl we dɛn nɔ stil gɛt mɛrɛsin fɔ Alzaima, mɛrɛsin dɛn de we go ɛp fɔ kɔntrol di sik ɛn mek layf izi smɔl. So, tide wi de tɔk bɔt wan spɛshal klas fɔ mɛrɛsin dɛn we dɔktɔ dɛn kin rɛkɔmɛnd fɔ dis.
Lɛ wi jɔs ɔndastand aw dis mɛrɛsin de wok, nɔto so?
Fɔ ɔndastand dis, lɛ wi fɔs luk aw wi bren de wok. Di nɛv sɛl dɛn na wi bren we dɛn kɔl nyuron, kin tɔk to dɛnsɛf ɛn chenj infɔmeshɔn tru kemikal mɛsenja dɛn, jɔs lɛk aw pɔsin we de post pɔsin kin sɛn lɛta dɛn.
Wan pan dɛn impɔtant mɛsenja dɛn de na asɛtilkolin . I kin ɛp wit bɔku impɔtant tin dɛn lɛk wi mɛmori, lanin, ɛn atɛnshɔn.
Bɔt we Alzaima sik bigin, di nɛv sɛl dɛn we de mek dɛn mɛsenja ya we dɛn kɔl asɛtilkɔlin kin pwɛl smɔl smɔl. Dɔn di nɔmba fɔ dɛn mɛsenja dɛn ya na di bren kin go dɔŋ. Di ɔda wan dɛn kin brok bay insɛf we dɛn dɔn fɔ du dɛn wok.
dis na di say we dεn dכn dεm we dεn kכ l Cholinesterase Inhibitors de kam in. dεn dכg dεm ya de wok bay we dεn de slo dכn di brok dכwn fכ di rεst asetylcholine mεsenja dεm. Dis min se dɛn kin kip dɛn ɛn alaw dɛn fɔ wok na di bren fɔ lɔng tɛm. Dis kin mek i ebul fɔ mɛmba ɛn tink gud wan fɔ sɔm tɛm.
Fɔ tɔk am simpul wan, dɛn mɛrɛsin ya nɔ de mɛn di sik. Bifo dat, dɛn kin kɔntrol di sik dɛn ɛn gi di pɔsin we sik fɔ sɔm tɛm.
Di mɛrɛsin dɛn we dɛn kin yuz we dɛn kɔl Cholinesterase Inhibitor
Bɔku Cholinesterase Inhibitor mɛrɛsin dɛn de we dɛn dɔn gri fɔ mɛn Alzaima sik ɔlsay na di wɔl ɛn na Sri Lanka. Yu dɔktɔ go pik di mɛrɛsin we go fayn fɔ yu bay aw di sik tan ɛn aw di pɔsin de.
| Nem fɔ di mɛrɛsin (brand nem) . | Yuz kes dɛn | Kɔmɔn sayd ɛfɛkt dɛn |
|---|---|---|
| Dɔnɛpɛzil (Arisɛpt) . | Fɔ di wan dɛn we nɔ kin gɛt dis sik, we nɔ kin bɔku, ɛn we nɔ kin rili bad. Dɛn kin tek am as wan tablɛt wan tɛm insay di de. | Nɔs, vɔmit, flatulɛns, mɔsul kramp, taya, nɔ want fɔ it. |
| Rivastigmin (Ɛksɛlɔn) . | Fɔ mild to mɔdaret kes dɛm (tablɛt). Yu kin gɛt am bak as skin pat fɔ siriɔs kes dɛm. | Nɔs, vɔmit, flatulɛns, nɔ kin want fɔ it, ɛn bɛlɛ pen (dɛn tin ya nɔ kin apin so we yu de yuz di pat). |
| Galantamin (Razadyne) we dɛn kɔl . | Fɔ di wan dɛn we nɔ gɛt dis sik, tek am tu tɛm insay di de ɔ as kapsul we de wok fɔ lɔng tɛm wan tɛm insay di de. | Nɔs, vɔmit, flatulɛns, nɔ want fɔ it, ed we de at , diziz. |
| Dɔnɛpɛzil + Mɛmantin (Namzarik) . | Dɛn kin mek am togɛda wit ɔda mɛrɛsin (NMDA agonist) fɔ di wan dɛn we gɛt di sik we gɛt mɔdaret to siriɔs. | Ed pen , kɔnfyushɔn, diziz, kɔnstipɛshɔn, nɔs, vɔmit. |
Wetin a go du if a gɛt sayd ɛfɛkt we a bigin fɔ tek di mɛrɛsin?
Sɔm pipul kin gɛt sayd ɛfɛkt wae dɛn fɔs bigin fɔ tek dis mɛrɛsin. Bɔt nɔ wɔri. Bɔrku tɛm, dɛn sayd ɛfɛkt ya go dɔn as yu bɔdi de yus to di mɛrɛsin. Yu dɔktɔ go ɔltɛm bigin yu pan wan rili smɔl doz ɛn smɔl smɔl i go inkrisayz di doz.
If yu gɛt nɔys, fɔ tek di mɛrɛsin wit it kin ɛp fɔ kɔntrol am. De tin wae impɔtant pas ɔl na fɔ tɔk to yu dɔktɔ bɔt ɛni diskɔmfɔt wae yu de gɛt. I go ebul fɔ gi yu di bɛst sɔlvishɔn.
Aw dis mɛrɛsin rili wok?
Dis na prɔblɛm fɔ bɔku pipul dɛn. Fɔ tɔk tru, di tin dɛn we kin kɔmɔt frɔm dɛn mɛrɛsin ya na fɔ shɔt tɛm nɔmɔ. Sɔm sik pipul dɛn kin si se di sik dɔn ridyus bad bad wan. Dɛn kin ebul fɔ tink klia wan smɔl, mɛmba tin dɛn, ɛn du wok dɛn we dɛn kin du ɛvride izi wan. Sɔmtɛm dis sik kin te fɔ sɔm ia.
Bɔt wi fɔ ɔndastand se dis tan lɛk fɔ put plasta oba tank we de lik fɔ sɔm tɛm. I go stɔp di wata fɔ lik fɔ sɔm tɛm, bɔt di pat go bi yuslɛs as di ol na di tank de big. Semweso, dɛn mɛrɛsin ya nɔ kin ebul fɔ stɔp ɔ rivɛns di damej we di bren kin gɛt we Alzaima sik kin kam wit. As tɛm de go, as di sik de go bifo, ɛn di bren we de mek asɛtilkolin de stɔp ɔlmost, dɛn mɛrɛsin ya sɛf nɔ de du ɛnitin.
Pipul dɛn de we nɔ fɔ tek dis mɛrɛsin?
Yɛs. Dis mɛrɛsin nɔ fayn fɔ ɔlman. Cholinesterase inhibitors kin mek di at rit ɛn blɔd prɛshɔn go dɔŋ. So, dɔktɔ dɛn kin rili tek tɛm we dɛn de gi dɛn to pipul dɛn we gɛt sɔm kayn wɛlbɔdi prɔblɛm.
- Pipul dɛn we gɛt asma
- Pipul wae gɛt at ritm abnɔmal
- Pipul wae gɛt kidni ɔr liva sik
- Pipul dɛn we gɛt ɔlsa na dɛn bɛlɛ
If di pɔsin we yu lɛk gɛt ɛni wan pan dɛn sik ya, mek shɔ se yu tɛl yu dɔktɔ bɔt am.
I rili impɔtant: Tɛl yu dɔktɔ bɔt ɛni mɛrɛsin , vaytamɛn, nyutrishɔn sɔpɔtmɛnt, ɛn ivin Ayurveda ɔ Sinhala mɛrɛsin we yu pɔsin we yu lɛk de tek. Sɔm mɛrɛsin (e.g., sɔm kol ɛn alɛji mɛrɛsin) kin intarakt wit dɛn Cholinesterase Inhibitors ya, we kin mek ɔl tu di mɛrɛsin dɛn nɔ wok ɔ mek dɛn gɛt denja sayd ɛfɛkt.
Mɛsej we dɛn kin kɛr go na os
- Cholinesterase inhibitors nɔto mɛrɛsin fɔ Alzaima sik. Dɛn kin jɔs kɔntrol di sayn dɛm wae gɛt fɔ du wit mɛmori ɛn tink fɔ sɔm tɛm.
- Dis mεdikeshכn de wok bay we i de inkrεs di lεvεl dεm fכ wan kεmikכl mεsenja we dεn kכl asetilkolin na di bren.
- Sɔm sayd ɛfɛkt lɛk fɔ nɔs ɛn vɔmit kin apin we yu bigin fɔ tek di mɛrɛsin, bɔt bɔku tɛm dɛn kin stɔp as tɛm de go.
- Nɔ ɛva stɔp fɔ tek mɛrɛsin ɔ chenj di doz if yu dɔktɔ nɔ advays yu.
- I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu pɔsin we yu lɛk de tek.
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