Yu dɔktɔ dɔn gi yu ɔ pɔsin we yu lɛk wan mɛrɛsin we dɛn kɔl Klɔzapin? If na so, i impɔtant fɔ tɔk bɔt dis mɛrɛsin sɔm tin dɛn. Bikɔs dis nɔ tan lɛk di mɛrɛsin we dɛn kin tek ɔltɛm, i nid fɔ pe atɛnshɔn to am smɔl, ɛn na tritmɛnt we rili wok. Lɛ wi tɔk bɔt ɔltin simpul wan ɛn klia wan.
Us kayn mɛrɛsin na dis Klɔzapin?
Fɔ tɔk am simpul wan, Clozapine na mɛrɛsin wae dɛn kin yuse fɔ trit mental sik dɛm lɛk schizophrenia . Bɔt, nɔto di fɔs tin we ɔlman kin disayd fɔ du. Dɔktɔ dɛn kin gi dis mɛrɛsin we ɔda tritmɛnt dɛn nɔ wok fayn lɛk aw dɛn bin de tink, ɔ we di sayd ɛfɛkt dɛn we ɔda mɛrɛsin dɛn kin gɛt nɔ kin ebul fɔ bia.
Dis de pan di grup fɔ drɔgs we dɛn kɔl ‘Antipsychotic’ . Dis mɛrɛsin de wok mɔ bay we i de balans di wok we di kεmikכl dεm lεk Dopamine εn Serotonin de du, we de εp fכ mek di nεv kכmyunikeshn na wi bren. Tru dis, i de mek di maynd stebul ɛn kɔntrol di sayn dɛm.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu dɔktɔ gi yu dis mɛrɛsin, i go nid fɔ gɛt kɔmplit pikchɔ bɔt yu wɛlbɔdi. So, if yu gɛt ɛni wan pan dɛn sik ya, mek shɔ se yu tɛl yu dɔktɔ bɔt dɛn.
- If yu dɔn ɛva gɛt alɛji fɔ Klɔzapin ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- If yu gɛt dayabitis ɔ if pɔsin na yu famili gɛt am.
- If yu gɛt tin dɛn lɛk at sik , ay kɔlɔstrel, ay/lɔ blɔd prɛshɔn, ɔ at bit we nɔ de bit ɔltɛm.
- If yu dɔn gɛt strok bifo dis tɛm .
- If yu gɛt ɛni sik na yu liva ɔ yu kidni .
- If yu gɛt wan sik lɛk aw yu blɔd nɔ de bɔku , yu wayt blɔd sɛl dɛn nɔ de bɔku, yu rɛd blɔd sɛl dɛn nɔ bɔku, ɔ yu pletlɛt dɛn nɔ bɔku.
- If yu kin gɛt kɔnstipɛshɔn bɔku tɛm ɔ yu kin gɛt blɔk na yu intestin.
- If yu gɛt sik we de mek yu sik ɔ yu gɛt kɔnvulshɔn.
- If yu gɛt wan sik we dɛn kɔl Parkinson .
- If yu gɛt dis maynia sik lɛk dis maynia sik.
- If yu gɛt prɔstat prɔblɛm ɔ yu gɛt prɔblɛm fɔ pis.
- If yu gɛt di ay sik we dɛn kɔl glaukoma.
- If i nɔ izi fɔ yu fɔ swɛla sɔntin.
- If yu na pɔsin we de smok. (Dis na impɔtant tin, wi go tɔk bɔt am leta).
- If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ.
If ɛnitin we de na dis list gɛt fɔ du wit yu, nɔ ayd am to yu dɔktɔ. I rili impɔtant fɔ yu sef.
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
- Tek di doz we yu dɔktɔ tɛl yu fɔ tek, jɔs lɛk aw dɛn tɛl yu fɔ tek am, ɛn di rayt tɛm. Swɛla di tablɛt wit wan glas wata.
- I nɔ mata if yu tek am bifo ɔ afta yu it.
- Nɔ tek am pas wetin di dɔktɔ tɛl yu fɔ tek, ɔ tek am bifo di tɛm we dɛn tɛl yu fɔ tek.
- Di tin we impɔtant pas ɔl: Nɔ stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm fɔ ɛni rizin we yu nɔ gɛt dɔktɔ advays. If yu du dat, dat kin mek yu gɛt siriɔs sayd ɛfɛkt. If yu nid fɔ stɔp fɔ tek di mɛrɛsin, du am smɔl smɔl, ridyus di doz, ɛn na ɔnda dɔktɔ in sɔpɔtishɔn nɔmɔ.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek mɔ pas di mɛrɛsin we dɛn tɛl yu fɔ tek, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm . Ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek dɛbul doz fɔ mek di doz we yu mis.
Speshal Wonin: If yu nɔ ebul fɔ tek yu mɛrɛsin fɔ pas tu dez (48 awa), nɔ bigin bak wit di sem doz. Mek shɔ se yu kɔl yu dɔktɔ fɔ advays.
Ɔda tin dɛn we kin mek yu gɛt prɔblɛm wit dis mɛrɛsin
Klɔzapin na wan mɛrɛsin wae kin miks wit ɔda mɛrɛsin, it, ɛn tin dɛm. So yu fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn ɛn ɛbul mɛrɛsin dɛn).
| Sɔbstans/drɔg kategori | Ɛgzampul dɛn ɛn simpul tin dɛn fɔ tɔk bɔt |
|---|---|
| Tin dɛn we yu nɔ fɔ ɛva tek | |
| Sɔm mɛrɛsin dɛn | Mεdisin dεm lεk Cisapride, Pimozide, Thioridazine. Yu dɔktɔ go tɛl yu bɔt dis. |
| Tin dɛm wae kin kam wit prɔblɛm ɛn fɔ tek am ɔnda dɔktɔ advays | |
| Rum | Nɔ drink rɔm we yu de tek dis mɛrɛsin. I kin mek yu slip ɛn diziz mɔ ɛn mɔ. |
| Kafin we gɛt kafin | Kafin, we de insay kɔfi, ti, ɛn sɔm sɔft drink, kin afɛkt di lɛvɛl we di klozapin de. Tɛl yu dɔktɔ bɔt di mɔni we yu de tek. |
| Fɔ smok | If yu smok, dat kin mek di klozapin we de na yu blɔd go dɔŋ. If yu de smok ɔ yu de tink bɔt fɔ lɛf fɔ smok, mek shɔ se yu tɛl yu dɔktɔ. Sɔntɛm yu go nid fɔ ajɔst di doz we yu de tek. |
| Ɔda mɛrɛsin dɛn | Sɔm mɛrɛsin fɔ kol, alɛji, pwɛl hat, nɔr kin slip, epilepsy, fungal infɛkshɔn, ɛn ay blɔd prɛshɔn kin miks wit dis. |
Tin dɛn we yu fɔ tek tɛm wit mɔ we yu de tek di mɛrɛsin
Yu fɔ no bɔt dɛn tin ya fɔ mek shɔ se yu sef we yu de tek klozapin.
Fɔ Tɛst fɔ di Blɔd we dɛn fɔ du
Dis na di tin we impɔtant pas ɔl. We yu bigin fɔ tek klozapin, yu fɔ du blɔd tɛst wan tɛm insay di wik fɔ di fɔs wik. Dis na fɔ chɛk di nɔmba fɔ di wayt blɔd sɛl dɛn we de na yu blɔd. Sɔntɛnde dis mɛrɛsin kin mek yu wayt blɔd sɛl dɛn go dɔŋ bad bad wan. Dis kin mek i nɔ izi fɔ yu fɔ fɛt di infɛkshɔn. If yu blɔd kɔnt fayn afta lɛk 6 mɔnt, yu dɔktɔ go mɔs tɛl yu fɔ du dis tɛst ɛvri tu wik.
Fɔ slip ɛn diziz
Dis mɛrɛsin kin mek yu fil lɛk se yu de slip ɛn yu ed de tɔn. So, nɔ du tin dɛn we nid fɔ de wach, lɛk fɔ drayv ɔ fɔ yuz mashin, te yu no aw dis mɛrɛsin de afɛkt yu. Nɔ tinap ɔ sidɔm wantɛm wantɛm.
Banbɛlɛ
Kɔnstipɛshɔn na kɔmɔn tin wit dis mɛrɛsin, bɔt i kin siriɔs. If yu nɔ gɛt bɔdi afta 2-3 dez, ɔ if yu gɛt sɔm sayn dɛn lɛk fɔ blo, bɛlɛ pen, ɔ nɔs, kɔl yu dɔktɔ wantɛm wantɛm. Drink bɔku wata.
Kɔntrol di tɛmpracha na di bɔdi
Dis mɛrɛsin kin mek yu nɔ ebul fɔ bia wit kol ɛn wam pasmak. So, drɛs fayn we di ples kol bad bad wan. Nɔ mek yu nɔ de na di san ɛn nɔ tray tranga wan we di wɛda wam pasmak. Drink bɔku wata.
Di sayd ɛfɛkt dɛn we di mɛrɛsin kin gɛt
Lɛk ɔl di mɛrɛsin dɛn, dis wan kin gɛt sayd ɛfɛkt. Sɔm pan dɛn siriɔs, sɔm pan dɛn kɔmɔn.
| Siriɔs sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ ɔ ETU wantɛm wantɛm | |
|---|---|
| Sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, trot we de at, mɔt so (dɛn kin bi sayn fɔ se di wayt blɔd sɛl nɔ bɔku). |
| Di sayn dɛn we de sho se pɔsin gɛt at | Chɛst pen, i nɔ kin izi fɔ blo, di at kin bit fast ɔ i nɔ kin bit ɔltɛm, di leg dɛn kin swel. |
| Sivɛri kɔnstipɛshɔn | Bɛlɛ pen bad bad wan, blo, vɔmit. |
| Di sik dɛn we kin mek pɔsin sik | If di bɔdi shek we i nɔ ebul fɔ kɔntrol. |
| NMS kwaliti dɛn | Yu kin gɛt ay fiva, yu mɔsul dɛn kin stif, yu kin swet pasmak, ɛn yu kin kɔnfyus. (Nyurolɛptik Malignant Sindrom) . |
| Alɛji dɛn we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip, tong. |
| Bɔku tɛm, i nɔ kin siriɔs, bɔt tɛl yu dɔktɔ if i kɔntinyu fɔ de. | |
| Fɔ pul wata pasmak | Dis kin apin mɔ na nɛt. |
| Drowsiness, diziz we pɔsin kin gɛt | Dis kin go dɔŋ as di bɔdi de ajɔst to di mɛrɛsin. |
| We yu de gɛt mɔ wet | Tɔk to yu dɔktɔ bɔt aw fɔ it ɛn ɛksesaiz. |
| Ed de at | I kin apin smɔl. |
Mɛsej we dɛn kin kɛr go na os
- Klɔzapin na tritmɛnt we rili wok fɔ di mental sik dɛn we nɔ dɔn ansa ɔda mɛrɛsin dɛn, bɔt dɛn fɔ tek am ɔnda strikt dɔktɔ in sɔpɔtishɔn.
- Nɔ ɛva stɔp fɔ tek mɛrɛsin ɔ chenj di doz if yu nɔ gɛt dɔktɔ advays.
- Di blɔd tɛst ɛvri wik ɔ tu wiks impɔtant fɔ mek yu sef. Nɔ skip dɛn.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek, ilɛksɛf yu de smok ɔ yu nɔ de smok, ɛn ɔl di prɔblɛm dɛn we yu gɛt.
- Go to dɔktɔ kwik kwik wan if yu gɛt sayn dɛn we de wɔn yu lɛk fiva ɛn trot we de at, yu chɛst de at bad bad wan, ɔ yu gɛt bad bad kɔnstipɛshɔn.
- If yu mis pas tu dez fɔ tek mɛrɛsin, tɔk to yu dɔktɔ bifo yu bigin bak.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Klozapin (Clozaril) tablɛt na di las tin fɔ yuz fɔ us sik?
Dis na di fɔs nyu jɛnɛreshɔn (Atypical) ekstrim pawaful drɔg we dɛn mek fɔ kɔntrol di siriɔs mental sik we dɛn kɔl ‘Schizophrenia’! Dɛn nɔ kin gi dis to ɔlman, dɛn kin yuz am fɔ di wan dɛn nɔmɔ we at fɔ du (Treatment-resistant) ɛn di wan dɛn we kin kil dɛnsɛf/Agresiv, we i tan lɛk se dɛn nɔ kin ebul fɔ yɛri di strenj vɔys dɛn we di pɔsin gɛt pan ɔl we dɛn de tek ɔl di ɔda mɛrɛsin dɛn.
💬 Wetin spɛshal bɔt dis (Clozapine) we de mek i wok pas ɔl ɔda mɛrɛsin?
כda saykayatrik mεdikeshכn dεm de blכk di dopamin (D2) rεsεpכta dεm na di bren. Dɔn di pɔsin we sik kin strɔng lɛk rɔbɔt. bכt dis Klozapin de blכk di dopamin D2 rεsεpכta dεm sכm sכm, insted i de blכk di sεrotonin (5HT2A) εn כda D4 rεsεpכta dεm na di bren rili strכng. Na dat mek as di sik de go bifo, i nɔ de gɛt da rigid sayd ɛfɛkt (EPS) de atɔl!
💬 Wetin mek i impɔtant fɔ chɛk di wayt blɔd sɛl dɛm fɔ pipul dɛm we de tek dis pil (Clozapine)?
Dis na di denja we pas ɔl ɛn we de kil pipul dɛn we dis mɛrɛsin gɛt! (Blak Bɔks Wɔnin). We dɛn tek dis, sɔm sik pipul dɛn ‘wayt blɔd sɛl (Neutrophils)’ we de fɛt sik dɛn na dɛn bɔdi kin pwɛl 100% ɛn ridyus am ɔl to ziro (Agranulocytosis)! Dɔn ivin smɔl kol vayrɔs kin kil di pɔsin. So, dɛn fɔ du ‘wik blɔd tɛst (ANC)’ fɔ di wan ol siks mɔnt we dɛn tek dis mɛrɛsin!
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