Yu ɔ pɔsin we yu sabi dɔn ɛva tɛl yu fɔ tek "blɔd thinner"? Sɔntɛm yu bin de fred smɔl we yu yɛri da nem de. Yu go dɔn tink se, "O, mi blɔd go tan?" Bɔt dɛn tin ya na rili impɔtant drɔgs we kin sev pipul dɛn layf if dɛn yuz dɛn kɔrɛkt wan. Tide wi de tɔk bɔt wan pan dɛn kayn nyu, advans klas fɔ drɔgs. Dɛn na Factor Xa Inhibitors.
Fɔ tɔk am simpul wan, wetin na dɛn Factor Xa Inhibitors ya?
Factor Xa Inhibitors na wan klas ɔf drɔgs we de mek yu blɔd nɔ klɔt abnɔmal wan. Wi kin kɔl dɛm "blɔd thinners" insay kɔlokyual wɔd dɛm. Bɔt dɔktɔ dɛn kin kɔl dɛn ``Direct Oral Anticoagulants'' ɔ ``DOACs''. Dɛn kin yuz dɛn fɔ lɔng tɛm fɔ trit blɔd we dɔn ɔlrɛdi fɔm, ɛn bak fɔ mek i nɔ klɔt tumara bambay.
Bɔku ɔda men kayn mɛrɛsin dɛn de we de insay dis kategori. Sɔntɛm yu dɔktɔ dɔn tɛl yu wan pan dɛn tin ya.
- Apixaban we dɛn kɔl Apixaban
- Betrixaban we de na di wɔl
- Ɛdɔksaban
- Rivaroxaban we dɛn kɔl Rivaroxaban
- Fondaparinux (Dis nɔto pil. Na injɛkshɔn we dɛn kin put insay di bɛlɛ)
Us kɔndishɔn dɛn kin yuz dis mɛrɛsin fɔ?
Dɛn kin yuse dis kayn mɛrɛsin fɔ trit ɛn protɛkt sɔm kayn mɛrɛsin wae rili impɔtant. Tink bɔt blɔd vesel we de insay wi bɔdi lɛk paip we de kɛr wata. If blɔd klɔt stɔp sɔmsay na dis paip, i kin mek big prɔblɛm. Na dat dis mɛrɛsin de ɛp fɔ mek yu nɔ gɛt am.
Yu kin gɛt gud aidia bɔt dis frɔm di tebul we de dɔŋ ya.
| Kɔndishɔn we dɛn de trit/prɛvɛnt | Wan simpul ɛksplen |
|---|---|
| Fɔ ridyus di risk fɔ gɛt strok | Sɔm pipul dɛm wae gɛt at bit we nɔr de bit ɔltɛm (atrial fibrillation) kin gɛt blɔd klɔt na di at dɛm we de go na di bren ɛn mek dɛn gɛt strok. Dis mɛrɛsin de ridyus da risk de. |
| Fɔ trit dip vein trombosis (DVT) . | Dis na kכndyushכn we bכdi kin fכm na di vein dεm we de dip insay di bכdi, spεshal wan na di leg dεm. Dis mɛrɛsin de ɛp fɔ sɔlv dɛn klot dɛn de. |
| Tritmɛnt fɔ Pɔlmonari Ɛmbolizm (PE) . | Dis kכndyushכn kin apin we wan bכdi we de kכlכt na di leg brok εn stכk insay wan vein na di lכng. Dis na tin we rili denja. Dis mɛrɛsin na tritmɛnt fɔ dat bak. |
| Fɔ mek yu nɔ gɛt venɔs tromboɛmbolizm (VTE) . | Dis na di nem we dɛn gi ɔl tu di DVT ɛn PE togɛda. Dis mɛrɛsin de mek dɛn kayn tin ya nɔ kam bak. |
| Fɔ ridyus di risk fɔ gɛt at sik ɛn blɔd vesel sik | Dis mɛrɛsin kin fayn bak fɔ pipul dɛm wae gɛt korona at sik ɛn periferik at sik. |
| Afta dɛn dɔn du big ɔpreshɔn | Afta dɛn dɔn du ɔpreshɔn fɔ chenj yu hip ɔ yu ni, yu go gɛt mɔ blɔd bikɔs yu de na bed nɔmɔ. Dɛn kin gi dis mɛrɛsin fɔ mek dis nɔ apin. |
Aw dis mɛrɛsin difrɛn frɔm Warfarin?
Yu go dɔn yɛri bɔt di drɔg we dɛn kɔl Warfarin. Na rili gud mɛrɛsin bak we de mek blɔd nɔ klɔt ɛn dɛn dɔn de yuz am fɔ lɔng lɔng tɛm. Bɔt di big prɔblɛm fɔ pɔsin we de tek Warfarin na fɔ gɛt fɔ du blɔd tɛst ɔltɛm . Dat min se yu fɔ go na ɔspitul wan tɛm insay di mɔnt, sɔntɛm tu tɛm insay di wik, fɔ gi blɔd ɛn du tɛst we de sho di tɛm we i tek fɔ mek di blɔd klɔt. Bay dɛn rizɔlt dɛn de, di dɔktɔ go inkrisayz ɔ ridyus di doz fɔ di mɛrɛsin.
Wan pan di big bɛnifit dɛn we Factor Xa Inhibitors gɛt na dat dɛn nɔ nid fɔ du blɔd tɛst ɔltɛm, we kin ridyus di prɔblɛm fɔ di pɔsin bad bad wan.
Aw dis mɛrɛsin de wok insay di bɔdi?
Dis rili intrestin. Tink bɔt di we aw blɔd kin klɔt lɛk we dɛn kin gɛda am na faktri. Bɔku tin dɛn de we wi fɔ du. di protin dεm kin kam togεda fכ mek di bכdi kכlכt.
Factor Xa na protin we na rili imכtant woka insay da "assembly prכsεs." Wetin dis drɔg de du na fɔ ambɔg di wok we da prɔtin we dɛn kɔl Factor Xa de du.. I tan lɛk se yu de blo smɔl frɔm wok fɔ sɔm tɛm. Dɔn di wan ol blɔd we de klɔt kin go bak to nɔmal. Dat min se blɔd we nɔ nid fɔ klɔt kin stɔp fɔ mek. Dɔn gɛt am?
Aw lɔng yu go gɛt fɔ tek dis mɛrɛsin?
Dis kin dipen pan di rizin we mek yu de tek di mɛrɛsin. I kin difrɛn frɔm wan pɔsin to ɔda pɔsin.
- If yu gɛt at bit we nɔ de bit ɔltɛm (atrial fibrillation): Yu kin nid fɔ tek dis mɛrɛsin fɔ di res ɔf yu layf.
- If yu gɛt blɔd we de klɔt na yu vein (VTE): I kin tek bitwin 3 ɛn 6 mɔnt.
- If yu gɛt blɔd we de klɔt na yu leg (DVT) ɔ yu lɔng (PE): I go tek lɛk 6 mɔnt.
- If afta dɛn dɔn du di ɔpreshɔn fɔ chenj di ni: Na 12 dez nɔmɔ afta dɛn du di ɔpreshɔn.
- Afta dɛn dɔn du di ɔpreshɔn fɔ chenj di hip: I go tek lɛk 35 dez afta dɛn dɔn du di ɔpreshɔn.
Di tin we impɔtant pas ɔl na fɔ tek yu mɛrɛsin jɔs lɛk aw yu dɔktɔ tɛl yu. Nɔ ɛva stɔp fɔ tek yu mɛrɛsin we yu nɔ aks yu dɔktɔ.
Wetin na di risk ɛn sayd ɛfɛkt dɛm we dɛn mɛrɛsin ya kin gɛt?
Jɔs lɛk ɛni ɔda mɛrɛsin, sɔm prɔblɛm dɛn de we kin mek pɔsin gɛt prɔblɛm. Bikɔs dɛn kin mek blɔd nɔ klɔt, di men tin we kin apin we pɔsin de tek dɛn mɛrɛsin ya na we pɔsin kin blɔd pas aw i kin kɔmɔt .
- Siriɔs blɔd: Na smɔl tɛm nɔmɔ, blɔd kin apin insay di bren ɔ na say dɛn lɛk di bɛlɛ ɔ di insay. I kin at fɔ kɔntrol dɛn tin ya. כltu naw spεshal dכg dεm de we dεn kכl ``rεvεrs εjεnt`` (e.g. andexanet alfa) we kin rivεs di ifekt dεm fכ dεn dכg dεm ya. Dɔktɔ dɛn kin yuz dɛn tin ya we pɔsin de blɔd we go mek i day.
- Smɔl smɔl sayd ɛfɛkt dɛn:
- Ivin if yu gɛt smɔl injury na yu bɔdi, yu kin notis blɔd spat (bruise) bɔku tɛm.
- Sɔm pipul dɛn kin gɛt wan sik we dɛn kɔl skin rash .
De impɔtant tin na dat, dis risk nɔr de pan dɛn mɛrɛsin ya nɔmɔ. Ɛnitin we de mek blɔd tan gɛt dis risk. So nɔ fred. Bɔt, i rili impɔtant fɔ tek tɛm.
Aw yu fɔ tek tɛm we yu de tek mɛrɛsin?
If yu de tek dis mɛrɛsin, i rili impɔtant fɔ protɛkt yusɛf frɔm aksidɛnt ɛn injuri as yu ebul. Ivin smɔl kɔt kin at fɔ stɔp blɔd. Na sɔm simpul advays dɛn we go ɛp yu.
| Wetin fɔ du | Wetin mek dat impɔtant? |
|---|---|
| Tek tɛm bad bad wan we yu de yuz shap tul dɛn (naif, siza). | If yu kɔt yu an, i kin tranga fɔ stɔp di blɔd. Tek tɛm wit nɛf we yu de was dish. |
| If yu de sheb, yuz ilɛktrik reza instead fɔ yuz reza we gɛt bled. | Di risk fɔ kɔt yusɛf wit di bled kin ridyus. |
| Wear glɔv ɛn sus we yu de wok na gadin. | Ivin wund frɔm sɔntin lɛk swɛlin ɔ chukchuk kin mek yu blɔd bɔku. |
| Tek tɛm wit tin dɛn we kin mek pɔsin slip ɛn fɔdɔm (rug, waya na grɔn) insay di os. | Injury we yu fɔdɔm, mɔ if yu nak yu ed, kin denja. |
Ustɛm a fɔ go to di dɔktɔ?
If yu gɛt ɛni wan pan dɛn sik ya we yu de tek dis mɛrɛsin, kɔl yu dɔktɔ wantɛm wantɛm, ɔ go na di ɔspitul imejensi rum (ETU) we de nia yu.
- Ebi ebi blɔd we nɔ go ebul fɔ stɔp: If dɛn nɔ ebul fɔ stɔp blɔd we de kɔmɔt na wund, nos, mɔt, ɔ gam.
- Fɔdɔm: If yu fɔdɔm sɔmsay, mɔ if yu nak yu ed, yu kin de blɔd insay yu bɔdi ilɛksɛf yu nɔ gɛt ɛni injuri we yu go si.
- If blɔd de na di stɔl (blak ɔ dak rɛd stɔl).
- If yu vɔmit blɔd (lɛk kɔfi grɔn ɔ rɛd).
- Bɔrku pen na yu chɛst, ed, ɔr bɛlɛ.
- I nɔ kin izi fɔ yu fɔ blo.
- Wan rash we kin kɔmɔt wantɛm wantɛm.
Dis mɛrɛsin dɔn ɛp bɔku pipul dɛn bikɔs dɛn nɔ nid fɔ mek dɛn tɛst dɛn blɔd ɔltɛm lɛk Warfarin. Bɔt dis mɛrɛsin nɔ fayn fɔ ɔlman. Tɔk to yu dɔktɔ fɔ disayd us mɛrɛsin go fayn fɔ yu. I nɔ mata us mɛrɛsin yu tek, i impɔtant fɔ fala yu dɔktɔ in instrɔkshɔn dɛn di rayt we.
Mɛsej we dɛn kin kɛr go na os
- Factor Xa Inhibitors na nyu, ifektiv klas fɔ drɔgs we de mek blɔd nɔ klɔt.
- We yu kɔmpia am wit ol mɛrɛsin lɛk Warfarin, yu nɔ nid fɔ du blɔd tɛst ɔltɛm we yu de tek dɛn wan ya. Dat na big tin we izi fɔ du.
- Di men risk fɔ dɛn mɛrɛsin ya na fɔ blɔd pasmak, so i rili impɔtant fɔ protɛkt yusɛf frɔm injury.
- Nɔ ɛva bigin, stɔp, ɔ chenj di doz fɔ ɛni mɛrɛsin if yu dɔktɔ nɔ advays yu.
- If yu gɛt blɔd we nɔ kɔmɔn ɔ ɔda tin dɛn we de mek yu sɔfa, go to dɔktɔ wantɛm wantɛm.
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