Yu tink se dɛn arenj yu bɔdi difrɛn we? Lɛ wi tɔk bɔt Heterotaxy Syndrome!

Di impɔtant pat dɛn we de insay wi bɔdi, lɛk di at, di lɔng, ɛn di liva, de na di sem ɔda ɛn na di rayt ples fɔ ɔlman, nɔto so? Dat na di nɔmal we. Bɔt tink bɔt am, sɔntɛnde dɛn ɔgan ya nɔ kin de usay dɛn fɔ de, bɔt dɛn kin de difrɛn we smɔl, na difrɛn say dɛn. Na dat wi go tok abaut tide, na somtin rare bot impotant kondishon we wi go aware of. Dɛn kɔl dis hɛtɛrotaksi sindrom.

Wetin na dis hεterotaksi sindrom?

Fɔ tɔk am simpul wan, heterotaxy syndrome na wan sik we di insay ɔgan dɛn na yu chɛst ɛn bɛlɛ de na difrɛn say dɛn pas aw dɛn go de. Tink bɔt am, we dɛn bɔn ɔlman, in ɔgan dɛn de na patikyula say dɛn na in bɔdi. Fɔ ɛgzampul, pɔrsin wae gɛt heterotaxy kin gɛt in at ɛn splin na di rayt say instead ɔf di lɛft say. Sɔntɛnde, dɛn chenj ya kin mek pɔsin gɛt siriɔs wɛlbɔdi prɔblɛm, ɛn i kin ivin mek pɔsin in layf de pan denja.

Di wɔd "heterotaxy" kɔmɔt frɔm di Grik langwej. "Heteros" min "difrɛn" ɛn "taksi" min "ɔda, arenjmɛnt". Dis min se dɛn fɔ arenj difrɛn we . sכmtεm dεn kin kכl dis "Heterotaxia" כ "Atrial Isomerism".

Us ɔgan dεm kin afɛkt bay hεterotaksi sindrom?

Dis kכndyushכn kin afekt di posishכn εn di wok we dεn כgan dεm ya na yu bכdi de du:

• At
• Lɔng
• Liva
• Spleen we de na di bɔdi
• Intestinal dɛn

Dis difrɛn frɔm `(Situs Solitus)` ɛn `(Situs Inversus)`?

Yɛs, dɛn tin ya na tri difrɛn tin dɛn.

• (Situs Solitus): Dis de tכk bכt di nכmal, εkspεkt posishכn fכ wi insay כgan dεm. Dis na aw bɔku pan wi gɛt wi ɔgan dɛn.
• (Situs Inversus): Dis na we di intan ɔgan dɛn de na di ɔda say we dɛn de, lɛk se dɛn de luk tru miro . Fɔ ɛgzampul, di at de na di rayt say instead na di lɛft say. Bɔrku tɛm, `(Situs Inversus)` nɔr kin gɛt big big wɛl bɔdi prɔblɛm.
• (Heterotaxy Syndrome): Dis nɔto jɔs we dɛn de chenj di ɔgan dɛn. Sɔm ɔgan dɛn nɔ kin fɔm fayn, ɔ i kin gɛt siriɔs prɔblɛm wit aw dɛn de wok. Dis na kɔndishɔn we kin mek yu gɛt mɔ kɔmpleks ɛn siriɔs wɛlbɔdi prɔblɛm pas `(Situs Solitus)` ɔ `(Situs Inversus)`.

Udat kin gɛt dis sik?

Hεterotaksi sεndrכm na wan jεnεtik vεryushכnƐnibɔdi kin gɛt wan sik we dɛn bɔn wit at sik. כltu, di kכndyushכn kin apin wan wan tεm, we min se nכbodi na di famili nכ bin gεt am bifo, εn na nyu jin mכtεshכn (`(sporadik כ de novo mכtεshכn)`). Bɔt if sɔmbɔdi na yu famili dɔn gɛt at sik we dɛn bɔn wit , yu risk fɔ bɔn pikin wit dis sik kin go ɔp smɔl.

Aw kɔmɔn tin dis kin apin?

Ɔlsay na di wɔl, dɛn se na lɛk wan pan ɛvri 10,000 pikin dɛn we dɛn jɔs bɔn kin gɛt di sik we dɛn kɔl heterotaxy syndrome. Bɔt sɔm stɔdi dɛn dɔn sho se dis sik kin kam mɔ bikɔs sɔntɛnde dɛn nɔ kin no bɔt am fayn.

bכt 3% pan di at kכndyushכn dεm we dεn bכn wit de riliyt to dis hεterotaksi sεndrכm.

Wetin na di sayn dɛm fɔ dis?

di men sayn na dat di insay כgan dεm na di chεst εn bכdi nכ de divεlכp lεk aw dεn bin de εkspεkt. sכ mtεm sכm כgan dεm kin nכ de, כ dεn nכ kin fכm fayn fayn wan we di εmbrayo stej. De sayn dɛm wae kin kam wit dis na:

• di insay כgan dεm (at, lכng, liva, splin, intestin) dεm we nכ de wok fayn.
• fכ gεt abnכmal strכkchכ fכ di at (congenital hat kכndishכn).
• Malrotation na di intestines.
• di splin we nכ de (Asplenia) כ divεlכpmεnt fכ di splin insay sεgmεnt dεm (Polysplenia).

Simptom dεm lεk dis kin apin bak biכs di insay כgan dεm nכ de wok fayn:

• I nɔ kin izi fɔ yu fɔ blo.
• Di rεsistεns to infεkshכn dεm dεn dכn dכn.
• Blu ɔ pale skin (Cyanosis).
• Bɛlɛ ɔ bɛlɛ de pen.
• I nɔ izi fɔ it, fɔ gɛt mɔ wet, ɔ fɔ digest it.
• Di at we nɔ de bit ɔltɛm.
• di akyumyuleshכn fכ mכkus כ wata na di lכng dεm.

Imajin, pikin de we dɛn jɔs bɔn, i nɔ izi fɔ blo, in bɔdi blu smɔl. We di dɔktɔ dɛn chɛk am, dɛn si se smɔl difrɛns de na di pikin in at, sɔntɛm di splin de na di ɔda say. Dɛn tin ya kin bi sayn fɔ `(Heterotaxy Syndrome)`.

Wetin kin mek dis apin?

difrεn tin dεm de we kin mek yu gεt hεterotaksi sεndrכm.

Di men tin we kin mek i apin na we di jɛnɛtiks chenj . di chenj dεm we de apin na pas 60 jin dεm kin afekt dis. Difrɛn we dɛn de we yu kin gɛt dis jenɛtik kɔndishɔn:

• fכ inhεrit wan kכpi fכ wan mutated jin frכm wan mama εn papa (`(Autosomal Dominant)`).
• inhεrit wan mכtayt kכpi fכ wan jin frכm di tu mama εn papa (`(Autosomal Recessive)`).
• wan nyu jεnεtik mכtεshכn we de apin (`(Sporadic כ De Novo)`) we nכ gεt famili histri.
• fכ gεt jεnεtik mכtεshכn pan yu X kromozom, we na wan pan yu sεks kromozom dεm (`(X-linked)`). dis kin kכmכn mכr pan man dεm, biכs dεn nכ gεt wan X kromozom.

Apat frɔm di jɛnɛtik kɔz dɛm, di tin dɛm we de apin na di envayrɔmɛnt bakfכ egzampl, we di mama gεt kεmikכl כ tכxik tin (e.g. peshכnal, tin dεm we gεt lid) we i bεlε, i kin mek dis kכndyushכn bak na di pikin we de divεlכp.

Ivin naw, dɛn de du ɔda stɔdi bɔt kes dɛm we dis sik kin apin we nɔ gɛt ɛni jɛnɛtik ɔ envayrɔmɛnt tin.

Aw yu kin no bɔt dis?

Dɔktɔ kin no se yu gɛt di sik we dɛn kɔl Heterotaxy syndrome afta i dɔn chɛk yu ɛn afta dat dɛn dɔn du wan ɔ mɔ tɛst dɛn we dɛn kin du fɔ tek pikchɔ, lɛk:

• Wan MRI skan (Magnetic Resonance Imaging) tɛst.
• Wan `CT` skan (Kɔmpyut Tomografi skan)`.
• Wan echocardiogram (wan ɔltra saund skan fɔ di at).

If, afta dɛn imej tɛst ya, di dɔktɔ sɔspɛkt se yu gɛt heterotaxy syndrome, i go ɔda fɔ mek dɛn du ɔda tɛst fɔ chɛk aw yu insay ɔgan dɛn de wok. Dɛn tin ya na:

• Blɔd tɛst fɔ chɛk di wɛlbɔdi na di splin.
• Ɛndoskopi (introdukshɔn fɔ wan tiub wit kamɛra) .
• Test we de chɛk aw di kidni dɛn de wok.
• Rɛnal Ɔltrasɔund.

Ustɛm dɛn kin no se pɔsin gɛt hɛtɛrotaksi sindrom?

dεn kin no dis kכndyushכn bifo dεn bכn am tru wan prεnatal כltra saund כ εkokadyografi (tεst fכ chεk di pikin in at). Bɔku pipul dɛn kin gɛt dis sik we dɛn bɔn dɛn. Dɛn kin no bɔt hɛtɛrotaksi we di sayn dɛm fɔ wan at sik we dɛn bɔn wit de. Sɔm pipul dɛm wae nɔr kin gɛt siriɔs sik kin no bɔt dɛn leta wae dɛn smɔl. Na smɔl tɛm nɔmɔ, dɛn kin no di sik bay we dɛn de du ɛgzamin fɔ ɔda sik we dɛn dɔn big.

Wetin na di tritmɛnt dɛn? `(Tritmɛnt)`

Di tritmɛnt fɔ heterotaxy syndrome nɔto di sem fɔ ɔlman. I dipen pan us ɔgan dɛn na yu bɔdi we dɛn afɛkt ɛn aw dɛn afɛkt dɛn bad bad wan .

Di tritmɛnt we dɛn kin yuz mɔ na ɔpreshɔn . Dɛn kin du dɛn ɔpreshɔn ya fɔ kɔrɛkt di tin dɛn we nɔ de apin na di divɛlɔpmɛnt ɔ wok we di ɔgan dɛn na di chɛst ɛn bɛlɛ de du. Fɔ trit dis sik kin nid fɔ du bɔku ɔpreshɔn ɔlsay na di pɔsin in layf, ɛn sɔntɛnde i kin bigin we i smɔl . Bɔku kayn ɔpreshɔn dɛn de:

• Ɔpreshɔn pan at: Ɔpreshɔn fɔ mek di at wok fayn ɔ fɔ kɔrɛkt di at abnɔmal tin dɛn we dɛn bɔn wit.
• Fontan Procedure : Dis na at ɔpreshɔn bak. i de mek wan chεmba (vεntrikul) fכ pכmp bכdi to di lכng dεm εn di bכdi.
• Ladd Procedure : Na ɔpreshɔn fɔ kɔrɛkt di twist ɛn tin dɛn we de ambɔg di insay.
• Fɔ transplant yu at`(Hat Transplant)`: Fɔ riples yu at wit dona at. Dis kin nid fɔ bi fɔ big pipul dɛn we dɛn dɔn du bɔku ɔpreshɔn pan dɛn at ɔlsay na dɛn layf.

Ɔda tritmɛnt dɛn we yu kin gɛt na:

• Implant wan pesmɛka fɔ kɔntrol di at ritm.
• Fɔ tek mɛrɛsin fɔ mek yu blɔd prɛshɔn go dɔŋ.
• Fɔ tek antibayɔtik (prophylactic antibiotics) fɔ ɛp di splin fɔ fɛt infɛkshɔn.

Aw kwik a go wɛl afta dɛn dɔn trit mi?

Di tɛm we yu kin tek fɔ mek yu wɛl afta di tritmɛnt kin difrɛn, i kin difrɛn frɔm di kayn ɔpreshɔn we dɛn bin du yu . Afta dɛn dɔn du di ɔpreshɔn, yu bɔdi nid fɔ rɛst fayn fɔ mek i wɛl. Afta bɔku pan di ɔpreshɔn dɛn we dɛn dɔn du fɔ yu at, yu go de na ɔspitul ɔnda 24 awa mɛdikal sɔpɔtishɔn fɔ sɔm dez to wiks fɔ si if di ɔpreshɔn bin wok fayn ɛn if ɛni sayd ɛfɛkt de. Afta sɔm tritmɛnt dɛn, i kin tek sɔm mɔnt fɔ mek yu bɔdi wɛl ɔl. Bifo yu du di ɔpreshɔn, yu dɔktɔ go ɛksplen to yu aw fɔ kia fɔ yu bɔdi afta dɛn dɔn du yu ɔpreshɔn ɛn wetin yu go du fɔ ɛp yu fɔ wɛl.

Yu tink se dɛn go ebul fɔ stɔp dis?

Bikɔs sɔm tin dɛn we kin mek pɔsin gɛt heterotaxy syndrome na bikɔs ɔf di chenj dɛn we de apin na di jɛnɛtiks , dɛn nɔ kin ebul fɔ stɔp dis sik ɔltogɛda. Yu kin tɔk to yu dɔktɔ bɔt aw fɔ tɛst yu jɛnɛtiks fɔ no bɔt di prɔblɛm dɛn we yu kin gɛt we yu gɛt bɛlɛ.

if yu bεlε, fכ avכyd fכ kכmכt to kεmikכl כ tכxin (e.g., peshכnal, prכduk dεm we gεt lid) we kin mek dis kכndyushכn na di pikin we de gro go εp fכ mek sכh se di pikin in hεlth.

Wetin na de layf wae pɔrsin wae gɛt dis sik kin liv?

Di layf we pɔsin we gɛt heterotaxy syndrome kin liv kin dipen pan aw di sik kin tranga. Di kayn bad bad tin dɛm wae kin kam wit dis sik, ivin wit tritmɛnt, kin mek pikin ɛn pikin dɛn layf de pan denja. Bɔt if di sik nɔr tranga, wit tritmɛnt ɛn ɔltɛm mɛdikal monitarin, i pɔsibul fɔ liv nɔrmal layf wit smɔl wɛl bɔdi prɔblɛm . If yu gɛt at bit we nɔ de bit ɔltɛm ɔ yu de fil pen na yu chɛst ɔ yu bɛlɛ, go to dɔktɔ wantɛm wantɛm.

Us tɛm yu nid fɔ go to dɔktɔ?

Si yu dɔktɔ if yu gɛt ɛni wan pan dɛn sayn ya:

• If yu skin tɔn blu ɔ pale grey.
• If yu nɔ ebul fɔ it ɔ drink.
• If yu gɛt wund we nɔ de wɛl, ɔ wund we swel, we de kɔmɔt yɔlɔ pus, ɔ we gɛt krɔkrɔs.

Ustɛm yu nid fɔ go na imejensi rum?

If na so i bi, go na imejensi rum wantɛm wantɛm, ɔ kɔl 1990:

• Bɔrku pen na yu chɛst ɔ yu bɛlɛ de pen.
• Wan at we nɔ de bit ɔltɛm.
• I nɔ kin izi fɔ yu fɔ blo.

Us kwɛstyɔn dɛn yu fɔ aks di dɔktɔ?

If dɛn no se yu gɛt heterotaxy syndrome, yu kin aks yu dɔktɔ kwɛstyɔn dɛn lɛk:

• Aw siriɔs di diagnosis we a gɛt?
• A nid ɔpreshɔn ɔ bɔku ɔpreshɔn?
• Aw yu kin rɛdi fɔ ɔpreshɔn?
• Aw lɔng i kin tek fɔ mek i wɛl afta dɛn dɔn du di ɔpreshɔn?
• Ɛni bad tin de we kin apin to di tritmɛnt dɛn we yu kin advays?

Wetin na `Isomerism`?

di wכd `Isomerism` dεn de yuz am na kεmεstri fכ dεskrεb kכmpawnd dεm we gεt di sem kεmikכl fכmula bכt difrεn strכkchכ dεm. dεn kכl di hεterotaksi sεndrכm bak `(Isomerism)` biכs yu insay כgan dεm nכ de na dεn rayt ples, bכt sכmtεm dεn kin du dεn bεsik wok dεm. Dat min se di aidia na dat pan ɔl we di shep ɔ pozishɔn difrɛn, di men tin we dɛn mek na di sem .

Wetin na di `ICD` kɔd fɔ dis kɔndishɔn?

Di Intanɛshɔnal Klasifikeshɔn fɔ Sik (ICD) na wan tul we dɔktɔ dɛn kin yuz fɔ klas di sik dɛn we pɔsin kin gɛt na di klinik. di ICD-10-CM kכd fכ hεterotaksi sεndrכm na Q89.3.

Wan impɔtant mɛsej fɔ mama ɛn papa ɛn mama ɛn papa dɛn we go kam

We yu kam fɔ no se yu nyu bɔbɔ gɛt heterotaxy syndrome, yu kin gɛt difrɛn filin dɛn. I ɔndastand se i rili at. Bɔt nɔ wɔri. Yu dɔktɔ dɛn, wit spɛshal pipul dɛn, go du dɛn bɛst fɔ mek shɔ se yu pikin gɛt wɛlbɔdi ɛn fɔ kɔntrol di sik dɛn so dat i nɔ go put in layf pan denja. di komplikashכn dεm εn di simptom dεm fכ dis kכndyushכn nid fכ kכntinyu fכ trit am εn monitar fכ mek sכh se di pikin in divεlכpmεnt εn ful layf nכ de ambɔg.

If yu de op fɔ gɛt pikin ɛn yu want fɔ ɔndastand di risk fɔ mek yu pikin gɛt wan jenɛtik kɔndishɔn lɛk heterotaxy syndrome, i impɔtant fɔ tɔk to yu dɔktɔ bɔt jenɛtik tɛst ɔ jenɛtik advays . Dis infɔmeshɔn go ɛp yu fɔ disayd fɔ du sɔntin we yu no. Mɛmba se i bɛtɛ ɔltɛm fɔ go to dɔktɔ fɔ ɛni wɛlbɔdi prɔblɛm.

` Hεterotaksi Sindrom, Hεterotaksi Sindrom, Intanεt כgan dεm, At sik, Dεfεkt dεm we dεn bכn wit, jεnεtik mכtεshכn, pikin hεlth