Sɔntɛnde yu kin fil se yu gɛt kɔnstipɛshɔn ɛn i nɔ kin izi fɔ yu fɔ swɛla afta yu dɔn tek strɔng mɛrɛsin fɔ mek yu fil pen? Dis na sɔntin we kin apin to bɔku pipul dɛn. So, tɛm lɛk dis, yu dɔktɔ kin gi yu spɛshal mɛrɛsin fɔ kɔntrol dis kɔnstipɛshɔn. Tide wi de tɔk bɔt wan pan dɛn kayn mɛrɛsin ya, we na Naloxegol.
Us kayn mɛrɛsin na Naloxegol?
Fɔ tɔk am simpul wan, Naloxegol na mɛrɛsin we de ɛp fɔ trit kɔnstipɛshɔn we kin apin we yu tek sɔm strɔng pen kil, mɔ di opioid pen kil .
Tink bɔt am, dɛn opioid pen kil ya nɔr de jɔs ridyus yu pen, bɔt dɛn de ridyus di aktiviti na yu intestines smɔl. Dat min se di mɔsul dɛn na yu insay de kɔntrakt ɛn push di stɔl fɔ go bifo smɔl smɔl. Naloxegol na di rayt tin we di drɔg de du fɔ sɔlv dis. Na wan drɔg we de insay di klas ɔf drɔgs we dɛn kɔl Opioid Blockers. Bɔt di spɛshal tin we dis wan gɛt na dat i kin wok mɔ na yu insay yu bɔdi. So, if yu nɔ gɛt bɔku tin fɔ ambɔg di ifɛkt we di mɛrɛsin we yu de gi yu pen gɛt, i de go na di insay nɔmɔ ɛn pul di ifɛkt we da pen kil de gɛt, ɛn ɛp di mɔsul dɛn na di insay fɔ wok fayn bak. Dɔn i kin izi fɔ pas stɔl.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin
Bifo yu bigin dis mɛrɛsin, i rili impɔtant fɔ gi yu dɔktɔ wan kɔmplit pikchɔ bɔt yu wɛlbɔdi. Mek shɔ se yu tɛl dɛn if yu gɛt ɛni wan pan di kɔndishɔn dɛn we de dɔŋ ya.
- If yu gɛt kansa ɔ yu gɛt tumbu na yu bɛlɛ, yu bɔdi, ɔ yu bɔdi.
- If yu gɛt wan sik lɛk Diverticulitis .
- If yu dɔn ɛva gɛt bɔdi blɔk bifo.
- If yu gɛt sik lɛk inflammatory bowel disease ( e.g. Crohn’s disease, ulcerative colitis).
- If yu gɛt sik na yu kidni ɔ yu gɛt liva sik.
- If dɛn jɔs dɔn du ɔpreshɔn pan yu bɛlɛ ɔ yu insay.
- If yu de tek wan kansa tritmɛnt lɛk bevacizumab .
- If yu gɛt alɛji to Naloxegol ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ.
Bay dis infɔmeshɔn, di dɔktɔ go disayd if dis mɛrɛsin fayn fɔ yu ɔ nɔ fayn fɔ yu ɛn aw fɔ gi am.
Aw a fɔ yuz di mɛrɛsin ɛksaktɔli?
Fɔ mek yu gɛt di bɛst pan yu mɛrɛsin, i impɔtant fɔ yuz am di rayt we.
1. Taym: Na wan tɛm nɔmɔ yu fɔ tek dis pil insay di de. Dat tu pan ɛmti bɛlɛ.Dat min se yu fɔ drink am fɔ lɛk wan awa bifo yu it brɛf, ɔ tu awa afta yu it.
2. Aw fɔ tek: Swɛla di tablɛt ɔl wit wan glas wata. Nɔ brok, krɔs, ɔ chew di tablɛt. Bɔt if i nɔ izi fɔ yu fɔ swɛla di tablɛt, yu kin krɔs am fayn fayn wan ɛn sɔlv am insay 4 ɔns (lɛk 120 ml) wata, ɛn drink am wantɛm wantɛm. Aks yu dɔktɔ bɔt dis.
3. Ɔda Laxatives: Nɔ yuz ɔda laxatives we yu de tek dis mɛrɛsin pas yu dɔktɔ tɛl yu fɔ tek am. If yu nɔr fil fayn afta yu dɔn tek dis mɛrɛsin fɔ 3 dez, tɛl yu dɔktɔ. I kin gi yu difrɛn mɛrɛsin fɔ mek yu nɔ gɛt bɛlɛ.
4. I rili impɔtant: If yu stɔp fɔ tek di opioid pen kil, yu fɔ stɔp bak fɔ tek Naloxegol . Dɛn kin jɔs gi dis mɛrɛsin fɔ kɔnstipɛshɔn we di opioid kin mek. Wae yu dɔn stɔp di opioid, yu nɔ go nid dis mɛrɛsin igen.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek dis mɛrɛsin tumɔs, nɔ panik ɛn kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm . Ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Ɔda tin dɛm wae kin intarakt wit dis mɛrɛsin (Interactions) .
Naloxegol na mɛrɛsin wae kin intarakt wit ɔda mɛrɛsin dɛm, so i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛm wae yu de tek.
| Tayp fɔ mɛrɛsin/sɔbstans | Tɔk bɔt |
|---|---|
| Nɔ yuz Naloxegol wit dɛn tin ya | |
| Antifungal we dɛn kɔl | Mɛrɛsin dɛn lɛk Ketoconazole ɛn Itraconazole |
| Antibayɔtiks | Mεdisin dεm lεk Clarithromycin εn Telithromycin |
| Mɛrɛsin fɔ HIV/AIDS | Sɔm mɛrɛsin dɛn we de agens di vayrɔs |
| Mek shɔ se yu tɛl yu dɔktɔ if yu de yuz dɛn tin ya. | |
| Grepfruit jus we dɛn kin mek | Greps ɔ grep jus kin miks wit dis mɛrɛsin. |
| Ɔda mɛrɛsin dɛn | Tin dɛm lɛk Diltiazem, Verapamil (fɔ at sik/hay blɔd prɛshɔn), Carbamazepine (fɔ ɛpilepsi), Rifampin (fɔ TB), Sɛnt Jɔn Wɔt (fɔ mental wɛlbɔdi). |
| Ɔda Opioid blɔk dɛn | Mɛrɛsin dɛn lɛk Naloxone ɛn Naltrexone |
Dis list nɔ kɔmplit. Nɔ fɔgɛt fɔ tɛl yu dɔktɔ bɔt ɛvri mɛrɛsin, ɔyl, ɔ vaytamɛn we yu de tek.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, Naloxegol kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt.
| Sayd ɛfɛkt we pɔsin kin gɛt | Wetin fɔ du |
|---|---|
| If ɛni wan pan dɛn tin ya apin, stɔp fɔ tek di mɛrɛsin ɛn go to dɔktɔ ɔ go na di imejensi rum wantɛm wantɛm. | |
| Bɛlɛ pen bad bad wan, we nɔ de chenj, ɔ we de wɔs. | dis kin bi siriכs sayn fכ damej pan di intestinal wכl (perforation). |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di lip, tong ɔ fes, i nɔ izi fɔ blo. |
| If dɛn tin ya kɔntinyu ɔ de mɔna yu, tɛl yu dɔktɔ. | |
| Bɛlɛ pen, nɔs, vɔmit | Dɛn tin ya kin go dɔŋ as di bɔdi de ajɔst to di mɛrɛsin. |
| Rɔnbɛlɛ | Dis na wan kɔmɔn sayd ɛfɛkt. |
| Gas, ed we de at | Bɔku tɛm, dɛn tin ya nɔ kin siriɔs. |
| Di simptom dɛm fɔ lɛf fɔ yuz opioid | Swet, kol, dayarɛa, bɛlɛ pen, nɔ de rɛst, ɛn fil wik. If yu gɛt ɛni wan pan dɛn sayn ya, tɛl yu dɔktɔ. |
Mɛsej we dɛn kin kɛr go na os
- Naloxegol na spɛshal mɛrɛsin we dɛn kin jɔs gi fɔ kɔnstipɛshɔn we opioid pen kil dɛn kin mek .
- Ɔltɛm tek dis mɛrɛsin wit ɛmti bɛlɛ , wan awa bifo ɔ tu awa afta yu it.
- Di tin we impɔtant pas ɔl: If yu stɔp fɔ tek di mɛrɛsin we de mek yu fil pen, mek shɔ se yu stɔp fɔ tek Naloxegol bak.
- If yu gɛt bad bad bɛlɛ pen we yu de tek di mɛrɛsin, i kin bi imejensi. Stɔp fɔ tek di mɛrɛsin wantɛm wantɛm ɛn go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU).
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn, vaytamɛn dɛn, ɛn ɔyl dɛn we yu de yuz.
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