Yu dɔktɔ dɔn tɛl yu ɔ sɔmbɔdi na yu famili fɔ bigin tek wan mɛrɛsin we dɛn kɔl Pacritinib? Na nɔmal tin fɔ gɛt sɔm kwɛstyɔn ɛn wɔri we yu yɛri bɔt dis kayn spɛshal mɛrɛsin. So, tide wi go tɔk bɔt ɔltin na wan rili simpul ɛn fayn fayn we, lɛk wetin dis mɛrɛsin bi, aw fɔ yuz am, ɛn wetin yu nid fɔ tek tɛm wit.
Wetin na dis mɛrɛsin we dɛn kɔl Pacritinib?
Fɔ tɔk am simpul wan, Pacritinib na wan mɛrɛsin we dɛn kin yuz fɔ mɛn wan sik we dɛn kɔl myelofibrosis . Maylofibrosis na kansa we kin apin na wi bon mכro. insay dis, di fayv tisu de tek di ples fכ di hεlty sεl dεm na di bon mכro, we de ambɔg di bכdi we de mek di bכdi.
Pacritinib de pan wan klas ɔf drɔgs we dɛn kɔl kinase inhibitors . Imajin se insay di sεl dεm na wi bכdi, sכm sכm mεsenja dεm (protein) de we de sho se di sεl dεm fכ gro εn sheb. Wetin dis drɔg de du na fɔ stɔp sɔm prɔtin dɛn we de ɛp dɛn sɛl dɛn de we sik fɔ gro. I tan lɛk we yu ɔf wan switch we nɔ fayn na mashin we de rɔn. dis we ya, fכ kכntrכl di growth fכ di sik sεl dεm na di men wok we dis dכg de du.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu bigin dis mɛrɛsin, i rili impɔtant fɔ mek yu dɔktɔ gɛt kɔmplit pikchɔ bɔt yu wɛlbɔdi prɔblɛm. Bikɔs da infɔmeshɔn de go sho if dis mɛrɛsin fayn fɔ yu, ɛn aw dɛn fɔ gi am. If yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl yu dɔktɔ.
| Status/habit we pɔsin gɛt | Tɔk bɔt |
|---|---|
| Blɔd ɛn blɔd we de klɔt | If yu dɔn gɛt prɔblɛm wit blɔd ɔ blɔd klɔt prɔblɛm trade. |
| At sik | If yu bin dɔn gɛt at atak, strok, ɔ ɔda at sik bifo. |
| Ɔda tin dɛn we kin apin to pɔsin we sik | Kɔndishɔn lɛk ɔda kansa, liva ɔ kidni sik, wan infekshɔn we dɔn de, dayarɛa, ɔ vɔmit. |
| Di we aw pɔsin de liv in layf | If yu na pɔsin we de smok tabak ɔ sigrɛt. |
| Plan dɛn fɔ tumara bambay | If yu go gɛt ɔpreshɔn tumara bambay. |
| Pɔsin in yon infɔmeshɔn | If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ. |
| Alɛji dɛn we pɔsin kin gɛt | If yu gɛt alɛji to pacritinib ɔ ɛni ɔda mɛrɛsin, it, ɔ day. |
Aw fɔ yuz di mɛrɛsin kɔrɛkt wan?
I rili impɔtant fɔ tek yu mɛrɛsin jɔs lɛk aw yu dɔktɔ tɛl yu fɔ tek, di rayt tɛm.
- Dis mɛrɛsin kin kam lɛk kapsul .
- Swɛla di kapsul ɔl wit wata . Nɔ ɛva chew am, brok am, ɔ krɔs am.
- Gɛt di abit fɔ tek yu mɛrɛsin di sem tɛm ɛvride. Da we de, yu nɔ go fɔgɛt.
- Yu kin tek dis mɛrɛsin bifo ɔ afta yu it.
- Kɔntinyu fɔ tek di mɛrɛsin te yu dɔktɔ tɛl yu fɔ stɔp.
Wonin: Dɛn dɔn gi yu dis mɛrɛsin fɔ yu nɔmɔ. Nɔ sheb am wit ɛni ɔda pɔsin fɔ ɛni rizin.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
Nɔ wɔri. If yu mis wan doz, skip am ɔltogɛda. Tek yu nɛks doz na di tɛm we dɛn dɔn sɛtul. Nɔ ɛva tek tu doz wan tɛm fɔ mek di doz we yu mis.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek mɔ pas di doz we dɛn tɛl yu fɔ tek, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm.Mek fon kɔl ɔ go na di ɔspitul Imejɛnsi Dipatmɛnt (ETU) we de nia yu .
Ɔda mɛrɛsin dɛm wae kin miks wit dis mɛrɛsin
I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn, ɛbul mɛrɛsin, ɛn sɔpɔtmɛnt), bikɔs sɔm mɛrɛsin kin miks wit pacritinib, chenj in ifɛkt ɔ mek in sayd ɛfɛkt bɔku.
Na mɔtalman, dɛn kin advays yu tranga wan fɔ nɔ tek pacritinib wit dɛn mɛrɛsin ya.
- Sɔm antivayrɔs drɔgs fɔ HIV ɔ AIDS
- Sɔm antibayɔtiks, lɛk klarithromycin ɛn ɛrythromycin
- Mεdisin dεm fכ fכn infεkshכn, lεk kεtokonazכl εn itrakonazכl
- Antiepileptic drɔgs lɛk carbamazepine ɛn phenytoin
- Rifampin bin de du am
- St. Jɔn in wɔt ɛbul prodak
Apat frɔm dat, i kin intarakt wit ɔda mɛrɛsin dɛn we kin mek chenj na di at ritm (lɔng di QT intaval). Dis list nɔ kɔmplit. So mek shɔ se yu tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
Tin dɛn we yu fɔ tek tɛm wit we yu de tek mɛrɛsin
- Chek-ap ɔltɛm: Yu dɔktɔ go aks yu fɔ kam na di klinik ɔltɛm fɔ wach yu kɔndishɔn. I go ɔda bak fɔ mek dɛn du blɔd tɛst (blɔd wok). Nɔ mis dɛn tin ya ɛn du dɛn ɔltɛm.
- Risk fɔ blɔd: Dis mɛrɛsin kin mek yu blɔd ɔ i izi fɔ brus. Tɛl yu dɔktɔ wantɛm wantɛm if yu notis ɛni blɔd we nɔ kɔmɔn (e.g., frɔm yu gam, nos) ɔ yu gɛt siriɔs brus.
- Risk fɔ gɛt infɛkshɔn: Dis mɛrɛsin kin ridyus di wok we yu imyun sistɛm de du smɔl. So, di risk fɔ gɛt infɛkshɔn kin bɔku. If yu gɛt sɔm sayn dɛm lɛk fiva, kol, trot we de at, ɛn kɔf, nɔr de mɛn yusɛf ɛn kɔl yu dɔktɔ. Tray fɔ de fa frɔm say dɛn we sik pipul dɛn de.
- Kansa risk: Sɔm pruf de fɔ se dis mɛrɛsin kin mek yu gɛt sɔm ɔda kayn kansa smɔl. Tɔk to yu dɔktɔ bɔt dis fɔ no mɔ.
- di ifekt pan fεtiliti: Dis mεdisin kin afekt man fεtiliti. If yu de op fɔ bɔn pikin, tɔk bɔt dis wit yu dɔktɔ bifo yu bigin fɔ trit yu.
- Fɔ gi yu pikin in mama in bɛlɛ: Nɔ gi yu pikin in mama in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 2 wik afta yu dɔn stɔp di mɛrɛsin.
Sayd ɛfɛkt dɛn we kin apin bikɔs ɔf mɛrɛsin
Lɛk ɛni mɛrɛsin, dis mɛrɛsin kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt. Bɔt, nɔto ɔlman kin gɛt dɛn. Dis dɔŋ ya na sɔm pan di sayd ɛfɛkt dɛm we pɔsin kin gɛt.
| Siriɔs sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
|---|---|
| Alɛji Riakshɔn dɛn | Skin rash, it, swel na di fes, lip ɔ tong. |
| Blɔd we de kɔmɔt | Blak ɔ blɔd stɔl, vɔmit sɔntin we tan lɛk kɔfi grɔn, rɛd spat na di skin, blɔd we nɔ kɔmɔn frɔm di yay/gɔm/nos. |
| Blɔd we De Klɔt | Chɛst pen, shɔt briz, leg pen, swel, ɔ wam. |
| Di sayn dɛn we de sho se pɔsin gɛt at atak | I nɔ izi fɔ blo, pen ɔ tayt na yu chɛst/nɛk/an, yu taya pasmak. |
| Di chenj dɛn we de apin na di at rit | Diziz, at bit fast ɔr nɔr de bit ɔltɛm, fil fɔ fil fayn. |
| Di sayn dɛn we de sho se pɔsin gɛt strok | Vishɔn kin chenj, kɔnfyushɔn, i nɔ kin izi fɔ tɔk ɔ ɔndastand, i nɔ kin fil fayn wantɛm wantɛm, i nɔ kin izi fɔ waka. |
| Ɔda | Sivɛri dayarɛa ɔ vɔmit, sayn dɛm fɔ infekshɔn (fiva, kol). |
| Tin dɛm wae nɔr kin siriɔs, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| De swɛl | Di anklɛ, fut, ɔ an dɛn kin swel. |
Mɛsej we dɛn kin kɛr go na os
- Pacritinib na mɛrɛsin we dɛn fɔ yuz wit big kia, na ɔnda dɔktɔ in advays nɔmɔ.
- Bifo yu bigin fɔ tek di mɛrɛsin, tɛl yu dɔktɔ bɔt ɔl yu mɛrɛsin ɛn ɔl di ɔda mɛrɛsin dɛn we yu de tek.
- If yu gɛt blɔd we nɔ kɔmɔn, sayn dɛn fɔ se yu gɛt di sik, ɔ ɔda bad bad tin dɛn we kin apin we yu de tek di mɛrɛsin, go to dɔktɔ wantɛm wantɛm.
- Nɔ sheb di mɛrɛsin we dɛn dɔn gi yu wit ɔda pipul dɛn fɔ ɛni rizin.
- If yu want fɔ gi pikin in bɛlɛ ɔ yu plan fɔ gɛt bɛlɛ, tɔk to yu dɔktɔ bifo yu bigin fɔ trit yu.
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