If yu gɛt sik we de mek yu sik wantɛm wantɛm, ɔ sɔntɛm yu gɛt ɛpilepsi, ɔ yu dɔn du ɔpreshɔn pan yu bren, yu dɔktɔ go dɔn gi yu dis mɛrɛsin fɔ stɔp yu sik. Dɛn kɔl am fenitoin injɛkshɔn. Fɔ tɔk am simpul wan, i de wok bay we i de mek di pat dɛn na yu bɔdi in nervɔs sistɛm we sɔm tɛm dɛn kin wok pasmak, kol ɛn kɔntrol. So lɛ wi tɔk mɔ bɔt dis, nɔto so?
Wetin na Fɛnitɔyn? Lɛ wi ɔndastand gud gud wan!
Fɛnitoin na wan impɔtant mɛrɛsin we dɛn kin yuz fɔ kɔntrol ɛn mek pɔsin nɔ gɛt sik . Bɔrku tɛm dɛn kin yuse am pan pipul dɛm wae gɛt epilepsy . Dɛn kin gi am bak fɔ ridyus di risk fɔ mek pɔsin sik we dɛn de du ɔpreshɔn pan in bren ɛn afta dɛn dɔn du am.
Tink bɔt di nɛv dɛn na wi bren lɛk smɔl waya dɛn we de kɛr ilɛktrik mɛsej. Sɔntɛnde dɛn "ways" ya kin gɛt smɔl "shɔt sɔrkwit." Na da tɛm de di sik kin apin. So, wetin Phenytoin de du na fכ kכl dכn dεn ova aktiv nεv dεm εn rεdכks dεn "sכt sכkshכn dεm." Dat min se i de kɔntrol di nerv dɛn we de wok pasmak.
Sɔntɛnde, dɔktɔ dɛn kin yuz dis mɛrɛsin fɔ ɔda tin, so if yu gɛt ɛni kwɛstyɔn, i go fayn fɔ aks yu dɔktɔ ɔ fama.
Wetin na de tin wae yu nid fɔ tɛl di dɔktɔ bifo yu gi yu dis mɛrɛsin?
Dis rili impɔtant. Bifo dɛn gi yu Fɛnitoin, i impɔtant fɔ mek di wan dɛn we de kia fɔ yu no bɔt dɛn tin ya:
- Yu dɔn adikshɔn to rɔm? Rɔm kin afɛkt di we aw dis mɛrɛsin de wok fayn.
- Yu kɔmɔt na Eshia? Sɔm pipul dɛm wae gɛt Eshian jin kin gɛt difrɛn we fɔ prosɛs dis mɛrɛsin na dɛn bɔdi, so i impɔtant fɔ no bɔt dis.
- Yu gɛt dayabitis (Diabetes Mellitus)? Dis mɛrɛsin kin afɛkt di blɔd shuga lɛvɛl.
- Yu gɛt at prɔblɛm?
- Yu gɛt liva sik? Dis mɛrɛsin de klin frɔm di bɔdi bay di liva. So if yu gɛt liva prɔblɛm, i kin afɛkt am.
- Yu gɛt lɔw blɔd prɛshɔn?
- Yu dɔn ɛva tink bɔt fɔ kil yusɛf, plan fɔ kil yusɛf, ɔ tray fɔ kil yusɛf? Ɔ ɛnibɔdi na yu famili dɔn ɛva gɛt wan? Dis impɔtant fɔ tɔk bɔt bikɔs dis mɛrɛsin kin afɛkt di we aw sɔm pipul dɛn de fil.
- Yu nɔ gɛt alɛji fɔ phenytoin, hydantoin, ɔda mɛrɛsin, it, day, ɔ tin dɛn we de mek yu nɔ pwɛl?Se sɔntin, ilɛksɛf na jɔs smɔl tin.
- Yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ?
- Yu na mama we de gi pikin in bɛlɛ?
I rili impɔtant fɔ yu yone sef fɔ tɛl di dɔktɔ dɛn tin ya ɛn nɔ ayd dɛn.
Aw yu kin yuz dis mɛrɛsin?
Dis na injɛkshɔn we dɛn kin put insay wan vein . Dis min se i nɔto sɔntin we yu kin yuz na os. Na mɛdikal pɔshɔnal dɛn we de na ɔspitul ɔ klinik sɛtin de gi yu .**
Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ ɛva gi ɔda pɔsin di mɛrɛsin we di dɔktɔ dɔn gi yu, ilɛksɛf dɛn gɛt di sem sayn dɛn we yu gɛt.
If dɛn gi dis mɛrɛsin to pikin dɛn: Insay sɔm kes dɛn we dɛn kin pik, dɛn kin gi dis mɛrɛsin to pikin dɛn bak. Bɔt spɛshal tin dɛn de we wi fɔ tink bɔt. Tɔk to yu mɛdikal tim bɔt dis.
Ovados: Dis nɔ kin apin bikɔs dɛn kin gi am na ɔspitul. Bɔt if yu tink se yu dɔn tek dis mɛrɛsin tumɔs, kɔl pɔyzin kɔntrol sɛnta ɔ imejensi rum wantɛm wantɛm.
Wetin if a mis wan doz?: Bikɔs dɛn kin gi dis na ɔspitul, i nɔ mata if yu mis wan doz. Di wan dɛn we de wok na di mɛrɛsin go tek kia ɔf am.
Wetin yu fɔ tek tɛm wit mɔ we yu de tek dis mɛrɛsin?
We yu gɛt dis vaysin, di mɛdikal wokman dɛn go tek tɛm wach yu kɔndishɔn. Bɔt i fayn fɔ mek yu no bɔt dɛn tin ya:
- Siriɔs riakshɔn dɛn na di skin: Dis rili impɔtant. Dɛn tin ya kin apin sɔm wik ɔr mɔnt afta yu bigin fɔ tek dis mɛrɛsin. Tɛl yu dɔktɔ wantɛm wantɛm if yu gɛt skin rash wit sɔm sayn dɛm lɛk fiva ɛn bɔdi pen. Dɛn rash ya kin tɔn rɛd ɔ pepul ɛn afta dat dɛn kin blista ɛn pul. Ɔ, if yu gɛt rɛd rash wit swɛlin na yu fes, lip, ɔ swɛlin limf no dɛm na yu nɛk ɔ armpit, tɛl yu dɔktɔ wantɛm wantɛm. Dis kin bi imejensi.
- Drɔw, diziz: Yu kin fil fɔ slip ɛn diziz. So, nɔ drayv, yuz mashin, ɔ du ɛnitin we nid fɔ pe atɛnshɔn te yu no aw dis mɛrɛsin de afɛkt yu. Nɔ grap ɔ sidɔm kwik kwik wan, mɔ if yu dɔn ol. Dis kin mek yu gɛt mɔ diziz ɛn fɔdɔm.
- Rɔm: Rɔk kin chenj di tin dɛn we dis mɛrɛsin de du, so nɔ drink rɔm ɔltogɛda.
- Tin dɛn we pɔsin kin tink bɔt fɔ kil insɛf:Dis mɛrɛsin kin mek yu tink ɔ du tin fɔ kil yusɛf smɔl. So pe atɛnshɔn mɔ to di we aw yu de tink ɛn aw yu de fil. If yu maynd de wɔs, yu fil lɛk se yu go day, ɔr yu fil bad ɔr wɔri pas aw yu kin fil , tɛl yu wɛl bɔdi tim wantɛm wantɛm. Nɔ ayd am.
- Vitamin D ɛn fɔlik asid we nɔ de: Dis mɛrɛsin kin mek di vaytamɛn D ɛn fɔlik asid lɛvɛl na di bɔdi go dɔŋ. So, tɔk to yu wɛlbɔdi tim bɔt di it dɛn we yu de it, di vaytamɛn dɛn we yu de tek, ɛn tek sɔpɔtmɛnt if nid de.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, Phenytoin kin mek sɔm sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, bɔt i fayn fɔ no bɔt dɛn.
Di sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm:
If yu gɛt ɛni wan pan dɛn sayn ya, tɛl yu dɔktɔ we yu nɔ go te:
- Alɛji: Skin de rɔsh, it, ayv, swel na yu fes, lip, tɔng, ɔ trot.
- Ay blɔd shuga (Hyperglycemia): Fɔ fil se yu tɔsti bad bad wan, yu nid fɔ pis bɔku tɛm, yu de fil taya pasmak, yu nɔ de si fayn.
- Di sayn dɛm fɔ infekshɔn: fiva, kol, kɔf, trot we de at.
- Liva injuri: Pen na di ɔp rayt say na di bɛlɛ, yu nɔ de want fɔ it, yu nɔ de fil fayn, yu de stɔl we gɛt layt kɔlɔ, yu urine we gɛt dak yɔlɔ ɔ brawn, yu yay ɔ yu skin de yɔlɔ, yu taya we nɔ kɔmɔn.
- Pen, swɛlin, blu/pɔpul diskɔlɔreshɔn, ɛn spred na di say we dɛn injɛkshɔn.
- Phenytoin toxicity: Yu nɔ de muv di yay we yu nɔ ebul fɔ kɔntrol, yu nɔ de balans ɔ i nɔ izi fɔ waka, i nɔ izi fɔ tɔk, yu taya we nɔ kɔmɔn, yu de nɔs, yu de vɔmit.
- Rash, fiva, ɛn limf no dɛm we swel.
- Rɛd, blista, pil, ɛn sɔntɛnde ivin insay di mɔt kin apin.
- Hat de bit sloslo: Yu kin fil lɛk yu ed de tɔn, yu kin fɔdɔm, yu kin kɔnfyus, yu nɔ kin blo fayn, yu kin taya we nɔ kɔmɔn.
- di limf no dεm we swεl na di nεk, groin, chεst, כ armpit.
- Filin lɛk fɔ tink bɔt fɔ kil yusɛf, fɔ de wɔs pan yu maynd, ɛn fɔ gɛt pwɛl hat.
- Brus ɔ blɔd we nɔ kɔmɔn.
Sayd ɛfɛkt dɛm wae nɔr kin denja, bɔt yu fɔ ripɔt to yu dɔktɔ if dɛn kɔntinyu fɔ de:
Bɔku tɛm, dɛn tin ya kin go insay sɔm dez. Bɔt if dɛn kɔntinyu fɔ du dat, tɛl yu dɔktɔ if dɛn de mɔna yu:
- I nɔ kin izi fɔ pe atɛnshɔn, fɔ mɛmba, ɔ fɔ tɔk.
- Diziz we pɔsin kin gɛt.
- Di we aw pɔsin kin slip.
- Ed de at .
Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn we pɔsin kin gɛt. If yu notis ɛni ɔda tin we nɔ de na di list, tɔk to yu dɔktɔ bɔt am.
Dis kin intarakt wit ɔda mɛrɛsin dɛn? (Drug Intarakshɔn) .
Dis na tin bak we rili impɔtant. Fɛnitɔyn kin miks wit bɔku ɔda mɛrɛsin dɛn, ɛvbɔdi dɛn, ɛn vaytamɛn dɛn. So tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (we dɛn gi yu, we yu kin bay, ɔyl, vaytamɛn, ɛn tin dɛn we yu kin it). Dɔn bak, tɛl yu dɔktɔ if yu de smok, drink rɔm, ɔ yuz drɔgs we nɔ rayt.
Nɔ ɛva tek Phenytoin wit dɛn mɛrɛsin ya:
If yu de yuz dɛn mɛrɛsin ya, i nɔ fayn fɔ tek Phenytoin. So, yu fɔ tɔk to yu dɔktɔ bɔt dis.
- Atimɛta
- Sɔm antivayral mɛrɛsin fɔ HIV ɔ epataytis
- Idelalisib we yu go yuz
- Isavukonazɔniɔm
- Lonafarnib we dɛn kɔl
- Lorlatinib we gɛt di sik
- Lumefantrine we dɛn kɔl
- Lurasidone we gɛt di sik
- Pakritinib we dɛn kin yuz
- Praziquantel we dɛn kɔl Praziquantel
- Ranolazin we dɛn kɔl Ranolazin
Fɛnitoin kin intarakt bak wit dɛn mɛrɛsin ya:
Dis list lɔng smɔl, bɔt if yu de yuz ɛni wan pan dɛn tin ya, nɔ fɔgɛt fɔ tɛl yu dɔktɔ.
- Albendazol we dɛn kɔl
- Rum
- Aspirin ɛn mɛrɛsin dɛn we tan lɛk aspirin
- Bleomycin we dɛn kɔl Bleomycin
- Kapɛsitabin we dɛn kɔl
- Kaboplatin we dɛn kɔl
- Sɔm mɛrɛsin fɔ blɔd prɛshɔn, at sik, ɛn at bit we nɔ de bit ɔltɛm
- Sɔm mɛrɛsin fɔ pwɛl hat, wɔri, ɔr ɔda kayn maynd sik
- Di mɛrɛsin dɛn we de mek pɔsin nɔ gɛt bɔku kɔlɔstrel lɛk Atorvastatin, Fluvastatin, ɛn Simvastatin
- Mεdisin dεm fכ fכn infεkshכn lεk Fluconazole, Itraconazole, Ketoconazole, Miconazole, Posaconazole, Voriconazole
- Ɔda mɛrɛsin dɛn we dɛn kin yuz fɔ mek pɔsin gɛt sik: Kabamazɛpin, Ɛtosuksimayd, Fɛlbamɛt, Lakɔsamid, Lamotrijin, Mɛtsaksimayd, Ɔkskabazepin, Fɛnobarbital, Tɔpiramɛt, Valproik asid, Vigabatrin
- Mɛrɛsin fɔ bɛlɛ prɔblɛm lɛk antasid, cimetidine , omeprazole, ɛn sucralfate
- Mɛrɛsin dɛn we de mek blɔd nɔ klin ɔ trit, lɛk Warfarin, Apixaban, Dabigatran, Edoxaban, ɛn Rivaroxaban
- Kloramfenikol we dɛn kɔl
- Klɔrpropamide we dɛn kɔl
- Sisplatin we dɛn kɔl Cisplatin
- Sayklɔspɔrin we dɛn kɔl
- Disulfiram we dɛn kɔl disulfiram
- Dɔksorubisin we dɛn kɔl
- Dɔksisayklin ( Dɔksisayklin ) .
- di uman hכmon dεm, fכ egzampl εstrojen εn bכn kכntrכl pil dεm
- Fluorouracil we dɛn kɔl Fluorouracil
- Fɔlik asid
- Irinotekan we dɛn kɔl
- Isoniazid we dɛn kɔl Isoniazid
- Mɔsul rilaksant dɛn we dɛn de du ɔpreshɔn
- Mɛtadɔn we dɛn kɔl
- Mɛtɔtreksɛt we dɛn kɔl
- Methylphenidate we gɛt di sik
- Paklitaksɛl we dɛn kɔl
- Fεnotiazin dεm (e.g. klorpromazin, mεsoridazin, prכklכpεrazin, tioridazin) .
- Rifampin bin de du am
- St. John’s Wort (dis na wan ɔyl) .
- Steroid mεdikeshכn dεm (e.g. prεdnison, kכtison) .
- Sɔlfadiazin we dɛn kɔl
- Sɔlfamɛtɔksazɔl
- Tenipɔsayd we dɛn kɔl
- Tiofilin we dɛn kɔl
- Tikagrelɔr we dɛn kɔl
- Tiklɔpidin we dɛn kɔl
- Tolbutamide we dɛn kɔl
- Vitamin D we gɛt di sik
Dis list nɔr de ɔlsay, so i bɛtɛ fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
Aw fɔ kip tin dɛn? (Dis nɔ go rili impɔtant to yu)
Bikɔs dɛn kin gi dis vaysin na ɔspitul ɔ klinik, bɔku tɛm yu nɔ kin wɔri fɔ kip am. Bɔt jɔs fɔ mek wi no se:
- Dɛn fɔ kip dis mɛrɛsin usay pikin dɛn nɔ go ebul fɔ rich.
- Dɛn fɔ kip am na rum tɛmpracha (bitwin 15 ɛn 30 digri sɛlshiɔs).
- Nɔ yuz mɛrɛsin we dɔn pas.
Dis infɔmeshɔn rili impɔtant to di wan dɛn we de wok na di ɔspitul.
Fɔ dɔn, di tin we impɔtant pas ɔl (Take-Home Message) .
Okay, so na di men tin dɛm we yu nid fɔ no bɔt di Phenytoin injɛkshɔn. Mɛmba se dis na impɔtant mɛrɛsin fɔ kɔntrol di sik we pɔsin kin gɛt.
Di tin we impɔtant pas ɔl na dat, if yu gɛt ɛni kwɛstyɔn, tin we de mɔna yu, ɔr nyu sayn, tɔk to yu dɔktɔ, nɔs, ɔ fama. Nɔ kip ɛnitin fɔ yusɛf. Dɛn de de fɔ ɛp yu.
Wi de wish yu fɔ wɛl kwik kwik wan!
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Us kayn pasɛnt dɛn kin gi Phenytoin Injection?
Dis na wan rili pawaful injεkshכn we de sev layf we dεn kin gi am wantεm wantεm insay di sikman in vein (IV) na כspitul fכ kכntrכl ‘Seizures / Epilepsy’, we na wan bren sik, εspεshali we di fit de las pas 5 minit wan tεm (Status Epilepticus). Dis kin mek di nerv dɛn na di bren kol ɛn stɔp di bad bad shek we pɔsin kin shek.
💬 Aw di Phenytoin injection de stɔp bren fit wantɛm wantɛm?
we sik de apin, di nεv dεm na di bren de rilis ilektrikal signal dεm (akshכn pכtεnshal dεm) wan wan εn we dεn nכ bin de εkspεkt. as dis fεnitoin injεkshכn rich di bren, i de kכmplit (blכk) di ‘sכdiכm chεnal dεm’ na dεn nεv dεm. Dɔn di kɔrɛnt kin stɔp fɔ lik ɛn di bren kin kol.
💬 Wetin na di risk dɛm we yu injekt dis vaysin insay wan vein (IV Injection)?
Dis na injɛkshɔn we dɛn fɔ tek tɛm gi am! dis na difrεnt injεkt ‘Slowly’ insay di vein (na wan rεt we na 50mg/min). If dɛn injɛkt am tumɔs kwik, di pɔsin in blɔd prɛshɔn kin go dɔŋ wantɛm wantɛm to ziro, ɛn di at kin stɔp (Cardiovascular collapse/Arrhythmias)! Dɔn bak, bikɔs dis mɛrɛsin nɔ de sɔlv insay wata, if di vein bɔs we dɛn de inj am, chans de fɔ mek di bɔdi we de rawnd am mɛlt ɛn rɔtin (Purple Glove Syndrome/Phlebitis).
` Phenytoin, Phenytoin, siiz, epilepsy, vaksin, sayd ifekt, bren ɔpreshɔn
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