Yu dɔn gɛt bɛlɛ we de at afta yu dɔn tek antibayɔtik? Lɛ wi lan bɔt Pseudomembranous Colitis!

Yu dɔn ɛva gɛt bɛlɛ we de at ɔ yu bɛlɛ bɔg afta yu dɔn tek wan kɔs fɔ antibayɔtik? Bɔku tɛm, i kin go afta wan ɔ tu dez. Bɔt sɔntɛnde, dis sik kin siriɔs smɔl. Tide wi go tɔk bɔt wan kayn siriɔs sik we kin gɛt fɔ du wit di yus fɔ antibayɔtik. Wi kin kɔl dis Pseudomembranous Colitis. Pan ɔl we di nem kin tan lɛk se i strenj smɔl, i rili impɔtant fɔ no bɔt am.

Fɔ tɔk am simpul wan, wetin na Pseudomembranous Colitis?

Dis na bad bad inflameshn (siv kol kol) we de apin na wi big intestin (colon), we min se wi de swel εn injuri. Imajin se sɔntin de pwɛl di dilik layn (mucosa) we de insay wi big intestinal. Dis damej kin bi bikɔs ɔf baktri, pɔyzin we da baktri de mek, ɔ ɔda sik.

we dis damej de apin, tik tik kכst plek dεm de fכm oba di εria dεm we inju. Jɔs lɛk aw krɔkrɔs kin fɔm na wi skin we wi gɛt wund. Bɔt dɛn tin ya nɔto rial krɔkrɔs. Dɛn mek dɛn wit day sɛl dɛn ɛn wayt blɔd sɛl dɛn. dis yכlכ-wayt mεmbran dεm na dεn dכkta dεn kכl "pseudomembranes." "Pseudo" min "fals." Dat min se na lay lay mɛmbran dɛn. dis kכndyushכn na wetin wi kכl pseudomembranous colitis.

Wetin na di sayn dɛm fɔ dis sik?

Pɔsin wae gɛt dis sik kin gɛt difrɛn kayn sayn dɛm, bɔt sɔm men tin dɛm de wae yu kin si.

Wetin mek dis kayn sik kin apin? Wetin na di men tin we kin mek i apin?

di men εn mכst kכmכn kכz fכ dis na infεkshכn wit di baktri Clostridium difficile , we wi kכl C. diff fכ sכt. Dis na di kɔz fɔ pas 90% pan di kes dɛm.

Naw yu kin de wɔnda aw dis C. diff baktri kin mek dis kayn sik. Di stori go lɛk dis:

Bɔku bɔku baktri dɛn, we gud ɛn bad, de na wi intestinal. Dɛn gud baktri ya kin du bɔku tin fɔ wi bɔdi. Naw imajin se dɔktɔ gi yu antibayɔtik fɔ ɔda sik (fɔ ɛgzampul, trot infɛkshɔn). Dɛn antibayɔtik ya kin kil di bɔdi we de na wi bɔdi. Bɔt we dɛn du dat, dɛn nɔ kin jɔs kil di bad bad bɔdi we mek wi gɛt di sik, bɔt dɛn kin kil bɔku pan di gud baktri dɛn we de na wi insay.

dis ova gro fכ C. diff baktri dεm de bigin fכ prodyuz tכxin dεm we de pwεl di layn na wi big intestin. dis tכxin dεm de mek di intestinal sεl dεm day εn inju, we de fכm di pseudomembranes we wi bin tכk bכt.

Antibayɔtik dɛm we kin mek pɔsin gɛt C. diff infεkshɔn

Pan ɔl we ɛni antibayɔtik kin mek dis prɔblɛm, sɔm kayn dɛn kin mek dis prɔblɛm. Sɔm pan dɛn tin ya na:

• Klindamaysin we dɛn kɔl
• Di kayn dɛn we dɛn kin yuz Sɛfalosporin
• Di kayn dɛn we dɛn kin yuz Pɛnisilin
• Di kayn dɛn we dɛn kin yuz Fluoroquinolones

Ɔda tin dɛn de we kin mek i apin apat frɔm C. diff?

Yɛs. pan ɔl we na C. diff infεkshɔn na di men tin we kin mek i apin, dis kכndyushכn kin apin bak bikɔs ɔf ɔda tin dεm, i nɔ kin apin so ɔltɛm.

• Ɔda baktriyal infɛkshɔn dɛn (e.g. *Staphylococcus aureus*, *E. coli*)
• Saytomegalovayrɔs infεkshɔn
• di bכdi we de fכm na di kכlon dכn (Ischemic colitis) .
• Sɔm kemotɛrapi mɛrɛsin dɛn fɔ kansa
• Sɔm sik dɛn we pɔsin kin gɛt we i de fɛt insɛf

Udat de pan denja fɔ gɛt dis sik?

Pan ɔl we ɛnibɔdi kin gɛt dis sik, sɔm pipul dɛn kin gɛt dis sik pasmak.

• Pipul dεm wae de gεt tritmεnt na כspitul: Ospitul na ples wae jεm lεk C. diff kin izi fכ spre.
• Pipul wae dɔn tek antibayɔtik dis biɛn tɛm: As wi bin dɔn tɔk bɔt, dis na di men tin wae kin mek pɔrsin gɛt dis sik.
• Pipul dɛn we dɔn pas 65 ia: Na bikɔs di bɔdi in immunity de go dɔŋ we dɛn de ol.
• Pipul dɛn we de na say dɛn we dɛn de kia fɔ ol pipul dɛn:
• Pipul wae gɛt wik imyun sistɛm: (e.g. pipul dɛm wae gɛt HIV, pipul dɛm wae gɛt kansa)
• Pipul dεm wae gεt כtoimyun sik dεm: (e.g. Inflammatory Bowel Disease - IBD)
• Pipul wae bin dɔn gɛt C. diff infεkshɔn bifo:

Us prɔblɛm dɛn kin apin if dis kin bi siriɔs?

Dis kin tan lɛk se yu de mek yu fred smɔl. Bɔt mɛmba se, bɔku tɛm, dɛn prɔblɛm ya kin apin nɔmɔ we di sik kam tranga ɛn dɛn nɔ gi dɛn di rayt tritmɛnt. Na dat mek wi kin se yu fɔ go to dɔktɔ kwik kwik wan.

• Di wata we de kɔmɔt na yu bɔdi ɛn di ilɛktrɔlayt imbalans: We yu gɛt 10-15 bɔdi muvmɛnt insay wan de, yu kin lɔs bɔku wata ɛn ilɛktrɔlayt. If dis kin tranga, i kin mek yu gɛt prɔblɛm dɛn lɛk we yu blɔd prɛshɔn go dɔŋ ɛn yu kidni nɔ de wok fayn.
• Toxic Megacolon: Dis na wan sik we rili denja. Wetin kin apin na di inflamɛns na di kɔlon kin so bad dat di kɔlon nɔ kin wok fayn, gas ɛn stɔl kin trɔp, ɛn di kɔlon kin so big dat i kin bɔs.
• Gastrointestinal perforation: If yu wund bad bad wan, i kin mek ol na di intestinal wall. if dis apin, baktri dεm we de kכmכt na di intestin kin go insay di bכdi εn mek infεkshכn dεm we de mek yu layf de pan denja (pεritonitis, sepsis).
• Sepsis: Na wan sik we kin mek pɔsin in layf de pan denja we infεkshɔn kin skata ɔlsay na di bɔdi ɛn di ɔgan dɛm na di bɔdi kin bigin fɔ wok.

Aw dɔktɔ kin no kɔrɛkt wan bɔt dis sik?

We yu go to dɔktɔ, i go aks yu bɔt yu sik, ɛni mɛrɛsin we yu jɔs dɔn tek (especially antibiotics), ɛn afta dat i kin du sɔm tɛst fɔ kɔnfirm se yu gɛt di sik.

1. Stɔl tɛst: Dis na di tɛst we impɔtant pas ɔl. dεn tek sεmpl fכ yu stכl εn tεst fכ si if C. diff baktri dεm כ tכxin dεm we di baktri dεm de mek de.

2. 2. .Blɔd tɛst: Dɛn tin ya kin ɛp fɔ chɛk fɔ si if pɔsin gɛt di sik ɛn fɔ mek di wayt blɔd sɛl dɛn bɔku.

3. Kolonoskopi: dis na fכ put wan tin tכb wit kεmεra tru di an fכ egzamin di insay pat pan di big intestin. dis de mek wi si wit tu yay if eni pseudomembrane de we wi bin tok boht. If nid de, dɛn kin tek smɔl pat pan di tisu (bayopsi) fɔ chɛk am.

Wetin na di tritmɛnt dɛm fɔ dis?

Di tritmɛnt de dipen pan wetin de mek di sik ɛn aw i siriɔs.

• Fɔ trit di kɔz: If na C. diff infɛkshɔn na di kɔz, yu dɔktɔ go gi yu wan patikyula antibayɔtik we kin kil di baktri dɛm. Metronidazole, Vancomycin, ɛn Fidaxomicin na sɔm pan dɛn mɛrɛsin ya.
• Sɔpɔtiv Keya: Dis kin inklud fɔ gi IV wata fɔ mek yu nɔ gɛt wata na yu bɔdi ɛn fɔ gi yu tin fɔ it insay yu bɛlɛ fɔ mek di intestin dɛn rɛst.
• כpεrayshכn: Insay kes dεm we rili siriכs, lεk kכmplikεshכn dεm lεk tכxik mεgakolon, i kin nid fכ כpεrayshכn fכ pul di pat pan di kכlon we dεn pwεl (colectomy). Bɔt, dis nɔ kin apin so ɔltɛm.

Wetin wi fɔ du fɔ sev dis kayn tin?

Fɔ mek dɛn nɔ du dis rili impɔtant, mɔ na say dɛn lɛk ɔspitul ɛn say usay dɛn de kia fɔ ol pipul dɛn.

• Wash yu an ɔltɛm: C. diff nɔ de yuz rɔm fɔ was yu an, so fɔ was yu an fayn fayn wan wit sop ɛn wata na di bɛst tin fɔ protɛkt yu.
• Aysolɛshɔn: Na ɔspitul, dɛn kin trit di wan dɛn we gɛt C. diff infɛkshɔn na wan sɛpret rum.
• Klin di say dεm: C. diff kin liv pan di say dεm fכ lכng tεm. I impɔtant fɔ klin di say dɛn ɔltɛm wit wan klorin-based disinfectant.

Ustɛm wi fɔ go to dɔktɔ kwik kwik wan?

If yu gɛt ɛni wan pan dɛn sik ya, go to dɔktɔ wantɛm wantɛm ɔ go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU).

Pan ɔl we i kɔmɔn fɔ mek yu bɛlɛ at pwɛl afta yu dɔn tek antibayɔtik, i nɔ kin izi so ɔltɛm. Sɔmtɛm i kin bi di biginin fɔ wan siriɔs sik lɛk Pseudomembranous Colitis. Na dat mek i rili impɔtant fɔ lisin to yu bɔdi. If yu gɛt ɛni dawt bɔt yu sik, nɔ shem fɔ tɔk to yu dɔktɔ. If yu gɛt di rayt tritmɛnt, yu kin wɛl frɔm dis sik kpatakpata.