Bɔku pan wi gɛt prɔblɛm wit ay kɔlɔstrel. I nɔmal fɔ mek yu fred ɛn wɔri smɔl we yu gɛt yu blɔd tɛst rizɔlt ɛn si se yu LDL lɛvɛl pas tri dijit. So, yu dɔktɔ dɔn tɛl yu fɔ bigin tek wan mɛrɛsin we dɛn kɔl statin fɔ kɔntrol yu kɔlɔstrel? Sɔntɛm yu dɔn de tek dis mɛrɛsin. So, yu go mɔs gɛt bɔku kwɛstyɔn bɔt dis mɛrɛsin, aw i de wok, ɛn di gud ɛn bad tin dɛn we i gɛt. Mek wi klia ɔl di kwɛstyɔn dɛn we yu gɛt bɔt am tide.
Fɔ tɔk am simpul wan, wetin na dɛn statin ya?
Statin na wan klas ɔf mɛrɛsin we dɛn kin tek nɔmɔ wit dɔktɔ in prɛskrishɔn. Dɛn men wok na fɔ mek yu kɔlɔstrel lɛvɛl nɔmal. sכm statin dεm kin ridyus yu LDL (Low-Density Lipoprotein) kכlestכl, we dεn kכ l bak di "bad" kכlestכl, bay 50% כ mכr.
Dɔktɔ dɛn kin kɔl LDL "bad" kɔlɔstrel fɔ wan rizin. Tink bɔt di at dɛn we de kɛr blɔd ɔlsay na yu bɔdi lɛk wata paip. Wetin dis LDL kɔlɔstrel de du na fɔ put insɛf na di wɔl dɛn na dɛn wata paip dɛn de lɛk mɔs. As tɛm de go, dɛn dipɔsit ya (wi kin kɔl dɛn plek) kin bɔku ɛn ridyus di ples we de insay yu blɔd vesel dɛn. Dis kin mek di at wok tranga wan fɔ pɔmp blɔd, ɛn i kin mek di blɔd nɔ flɔ bak.
Statin nɔ jɔs de mek di LDL go dɔŋ. Dɛn kin mek bak ɔda kayn fat we de na yu blɔd we dɛn kɔl triglisɛrɛyd. Dɛn kin ɛp bak fɔ mek yu liva pul di kɔlɔstrel we yu nɔ want. Sɔntɛnde dɛn mɛrɛsin ya kin mek yu gɛt mɔ HDL (High-Density Lipoprotein) bak, we dɛn kɔl di "gud" kɔlɔstrel . HDL "gud" biכs i de kכlekt kכlestכl we yu nכ want frכm כlsay na di bכdi εn de gi am to di liva. Dɔn di liva kin pul am na di bɔdi.
Dɛn mɛrɛsin ya kin kam lɛk tablɛt ɔ kapsul. Dɛn kin tek dɛn wan tɛm insay di de. Dɛn kin tek dɛn wit it ɔ atɔl it. Di tin we impɔtant pas ɔl na fɔ tek dɛn di sem tɛm ɛvride. Di lɛbl we de na yu mɛrɛsin bɔtul go tɛl yu us tɛm pan di de fɔ tek dɛn. Bɔku tɛm, dɛn kin tek di statin dɛn we de wok fɔ shɔt tɛm na nɛt bikɔs wi bɔdi kin mek mɔ kɔlɔstrel na nɛt we wi de slip. Bɔt di statin dɛn we de wok fɔ lɔng tɛm nɔ kin wok fayn ɛni tɛm pan di de.
Okay, naw lɛ wi si aw dis mɛrɛsin de wok insay di bɔdi.
Dis na tin we rili simpul fɔ ɔndastand. Imajin se na yu liva na di men faktri we de mek kɔlɔstrel. 75% pan di kכlestכl we wi bכdi nid na dis liva de mek am. Di ɔda wan de kɔmɔt frɔm di it we wi de it.
So, fɔ mek dis faktri we de mek kɔlɔstrel wok, i nid pɔsin we impɔtant fɔ wok. dat na wan εnzym we dεn kכl HMG-CoA rεduktaz. I tan lɛk se yu nid masta mɛkanik fɔ mek motoka.
Statin dɛn kin du wan wok we rili klia. I tan lɛk sekyuriti gad na di get na faktri. di statin dεm de stכp di HMG-CoA rεduktaz εnzym fכ go insay di fכktri. Dat min se, dɛn kin blok am. Wetin kin apin da tɛm de? biכs di men "wokman" we de mek kכlestכl dכn dכn, di kכlestכl we di liva de prodyuz de rεdכks bכku bכku wan. Dis na aw di statin dɛn kin kɔntrol di kɔlɔstrel lɛvɛl na yu blɔd.
Fɔ tɔk am simpul wan, di statin dɛn kin ambɔg di we aw di liva de mek kɔlɔstrel, ɛn dis kin mek di bad kɔlɔstrel (LDL) we de na di blɔd go dɔŋ.
Wetin mek wi nid dɛn statin ya?
Di men rizin na fɔ ridyus di risk fɔ gɛt at atak ɛn strok.
Kɔlɔstrel impɔtant fɔ mek wi bɔdi mek vaytamɛn D, ɔmon, ɛn asid dɛn we de ɛp fɔ digest it. Bɔt di prɔblɛm na dat, tumɔs kɔlɔstrel kin bɔku na di blɔd.
As a bin dɔn tɔk, dis ɛkstra kɔlɔstrel kin bigin fɔ gɛda insay di blɔd vesel dɛn. Wi kin kɔl dis atɛrosklɛrosis. As tɛm de go, dɛn tin ya we de na di blɔd (plaque) kin mek di blɔd vesel dɛn smɔl. Dɔn, ples nɔ kin de fɔ mek di blɔd flɔ. I tan lɛk se trafik jam na rod we bɔku pipul dɛn kin pas.
Di tin kin wɔs pas dat. Sɔntɛnde, di kɔlɔstrel we dɔn gɛda insay dɛn blɔd vesel dɛn de kin nɔ stebul ɛn i kin bɔs wantɛm wantɛm. If blɔd klɔt de, i kin blok di blɔd vesel kpatakpata. If dis blok de apin na wan at we de gi blɔd to di at, i kin mek pɔsin gɛt at atak . If i apin na wan at we de gi blɔd to di bren, i kin mek pɔsin gɛt strok . Statin de mek di kɔlɔstrel smɔl ɛn protɛkt wi frɔm dɛn siriɔs tin ya.
Us kayn statin de na di makit?
Bɔku kayn statin dɛn de. Yu dɔktɔ go chɛk yu sik ɛn no di kayn ɛn doz we go fayn fɔ yu.
| Statin drɔg nem (Jɛnɛrik Nem) . | Kɔmɔn Brand Nem dɛn |
|---|---|
| Atorvastatin we dɛn kɔl am | Lipitor®, Kaduet®, ɛn ɔda pipul dɛn |
| Fluvastatin we dɛn kɔl Fluvastatin | - . |
| Lovastatin we dɛn kɔl lovastatin | Mevakɔr®, AltɔprɛvTM, ɛn ɔda pipul dɛn |
| Pitavastatin we dɛn kɔl Pitavastatin | Livalo®, Zypitamag®, ɛn ɔda pipul dɛn |
| Pravastatin we dɛn kɔl Pravastatin | - . |
| Rosuvastatin we dɛn kɔl Rosuvastatin | Krestɔ®, Ɛzalɔr Sprinkl® |
| Simvastatin we dɛn kɔl Simvastatin | Zokor®, FloLipid®, Vytorin®, ɛn ɔda pipul dɛn |
Sɔntɛnde, dɛn kin gi wan statin drɔg insay wan kɔmbayn pil wit ɔda mɛrɛsin.
- Simvastatin wit ɛzetimib ɔ niasin
- Atorvastatin wit ɛzetimib ɔ amlodipin
- Lovastatin wit niasin
Udat fɔ tek statin?
Dis na kwɛstyɔn we rili impɔtant. Statin nɔto wan saiz drɔg. Dɔktɔ go gi yu dis mɛrɛsin bay di ɔl di risk we yu gɛt fɔ gɛt at ɛn blɔd vesel sik.
Tipikli, dεn kin rεkomεnd statin fכ:
- Fɔ di wan dɛn we nɔ ebul fɔ kɔntrol dɛn kɔlɔstrel lɛvɛl bay we dɛn de it ɛn ɛksesaiz .
- fכ sכm pipul dεm, bikoz fכ di jεnεtik rizin dεm (jin dεm), dat na, di bכdi de mek mכr kכlestכl pas aw i nid. Fɔ dɛn pipul dɛn de.
- Fɔ di wan dɛn we gɛt tin dɛn we kin mek dɛn gɛt at sik, lɛk dayabitis, ay blɔd prɛshɔn, ɛn fɔ tek tabak.
We yu de disayd if yu nid statin, yu dɔktɔ go tink bɔt bɔku tin dɛn, lɛk yu ej, man ɔ uman, ɛn yu famili istri. Dɛn kin gi statin fɔ big pipul dɛn ɛn sɔm tɛm dɛn de, dɛn kin gi yɔŋ pikin dɛn.
Na sɔm tin dɛn we dɔktɔ dɛn kin tɛl yu fɔ yuz statin:
- Fɔ di wan dɛn we dɛn bad kɔlɔstrel (LDL) lɛvɛl rili ay, pas 190 mg/dL, ɛn dɛn nɔ kin ebul fɔ kɔntrol dɛn bay we dɛn chenj dɛn layf.
- Pipul dεm we ol bitwin 40-75 ia wit dayabεtis εn LDL lεvεl we pas 70 mg/dL.
- Fɔ di wan dɛn we dɔn gɛt at atak, strok, ɔ peripheral artery disease (PAD) bifo tɛm.
- Fɔ di wan dɛn we ol 40-75 ia, wit LDL lɛvɛl we pas 70 mg/dL ɛn we gɛt ay risk fɔ gɛt at sik.
Yu tink se statin gɛt sayd ɛfɛkt?
Lɛk ɛni mɛrɛsin, statin kin mek yu gɛt sayd ɛfɛkt. Bɔt di impɔtant tin na dat bɔku pipul dɛn nɔ kin gɛt ɛni sayd ɛfɛkt. Ilɛksɛf dɛn du dat, bɔku pan dɛn na smɔl pipul dɛn.
Bɔt, i rili impɔtant fɔ mek yu no bɔt dis. If yu gɛt ɛni sayd ɛfɛkt, yu fɔ tɛl yu dɔktɔ. Dɔn i kin ajɔst yu doz ɔ chenj yu to difrɛn statin.
| Di sayd ɛfɛkt dɛn we kɔmɔn ɛn we nɔ kin apin so ɔltɛm | |
|---|---|
| Kɔmɔn smɔl smɔl sayd ɛfɛkt dɛn |
|
| Rarely siriɔs sayd ɛfɛkt dɛn |
|
Impɔtant: Tek tɛm wit Grep ɛn Pomegranate!
Yu dɔktɔ kin advays yu fɔ avɔyd grep ɔ pomegranate jus we yu de tek sɔm statin (especially Atorvastatin, Lovastatin, Simvastatin). Dis na bikɔs dɛn frut ya kin ambɔg di bɔdi in ebul fɔ brok di statin. Dis kin mek di mɛrɛsin bɔku pasmak na yu bɔdi, ɛn dis kin mek yu gɛt mɔ sayd ɛfɛkt. Mek shɔ se yu aks yu dɔktɔ bɔt dis.
Kwɛstyɔn dɛn we dɛn kin aks bɔku tɛm bɔt statin
Wetin go apin if yu stɔp fɔ tek statin wantɛm wantɛm?
Dis na tin we rili denja. If yu stɔp fɔ tek statin we yu nɔ gi yu dɔktɔ advays, yu kɔlɔstrel go bigin fɔ go ɔp bak. Dat min se yu risk fɔ gɛt at atak ɛn strok go bɔku bak. Dis tan lɛk we yu pul ambɔla na di huk we ren de kam. Di protɛkshɔn we di mɛrɛsin de gi go lɔs. So nɔ stɔp fɔ tek di mɛrɛsin fɔ ɛni rizin we yu nɔ aks yu dɔktɔ.
Yu tink se statin kin mek yu gɛt mɔ wet?
Sɔm stɔdi dɔn sho se statin kin mek yu gɛt smɔl smɔl wet. Wan ɔda tin na dat, we sɔm pipul dɛn bigin fɔ tek di mɛrɛsin, bikɔs dɛn kɔlɔstrel lɛvɛl fayn, dɛn kin tink se, "Naw a dɔn fayn," ɛn nɔ de tek tɛm kɔntrol dɛn it ɛn ɛksesaiz. Ivin da tɛm de, dɛn kin gɛt mɔ wet. Mɛmba se ivin if yu tek statin, i impɔtant fɔ mek yu kɔntinyu fɔ liv fayn layf.
Ustɛm a fɔ go to dɔktɔ we a de tek dis mɛrɛsin?
If yu gɛt ɛni wan pan dɛn sik ya we yu de tek statin, tɛl yu dɔktɔ wantɛm wantɛm:
- Pen na di mɔsul ɔ di jɔyn dɛn we yu nɔ go ebul fɔ bia
- Wik
- Fiva
- Yu yay ɔ yu skin kin yɔlɔ (Jaundice) .
- Dak urine
Pipul dɛn de we nɔ fɔ tek statin?
Yɛs. Statin nɔ fayn fɔ sɔm pipul dɛn.
- Fɔ uman dɛn we gɛt bɛlɛ
- Fɔ mama dɛn we de gi pikin in bɛlɛ
- Fɔ pipul dɛm wae gɛt sɔm kayn bad bad liva sik dɛm
If yu gɛt dayabitis, tɛl yu dɔktɔ. Fɔ pɔsin we dɔn ɔlrɛdi de pan denja fɔ gɛt dayabitis, statin kin mek da risk de bɔku smɔl. Bɔt bikɔs pipul dɛn we gɛt dayabitis kin gɛt bɔku prɔblɛm wit at sik, di bɛnifit dɛn we statin kin gi kin pas di smɔl risk fa fawe. Yu dɔktɔ na di bɛst pɔsin fɔ disayd dis.
Mɛsej we dɛn kin kɛr go na os
- Statin na impɔtant mɛrɛsin wae de ridyus di bad kɔlɔstrel (LDL) na yu blɔd ɛn protɛkt yu frɔm di risk fɔ gɛt at atak ɛn strok.
- Na yu dɔktɔ nɔmɔ go disayd if yu nid dis mɛrɛsin ɔ nɔ nid am, us kayn mɛrɛsin, ɛn us doz.
- Nɔ ɛva stɔp fɔ tek statin ɔ chenj di doz we yu nɔ go to yu dɔktɔ.
- If ɛni sayd ɛfɛkt apin (especially mɔsul pen), tɛl yu dɔktɔ wantɛm wantɛm.
- Nɔ fɔgɛt fɔ fala wɛlbɔdi it ɛn ɛksesaiz rutin we yu de tek statin. Di bɛst tin kin kɔmɔt frɔm we dɛn jɔyn dɛn ɔl tu.
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