Wi no se fɔ liv wit dis sik we dɛn kɔl Pakinsin kin tranga sɔntɛnde. I nɔ izi fɔ pas di de wit tin dɛn lɛk fɔ shek shek ɛn fɔ waka sloslo . So dɔktɔ dɛn kin gi dɛn difrɛn mɛrɛsin dɛn fɔ kɔntrol dɛn sik ya. Tide wi go tɔk bɔt wan pan dɛn kayn spɛshal mɛrɛsin ya, we na Tolcapone. Dis nɔto mɛrɛsin we dɛn kin gi dɛn wan. Dɛn kin gi am wit levodopa- carbidopa , we na di men mɛrɛsin fɔ di sik we dɛn kɔl Pakinsin . Fɔ tɔk am simpul wan, i tan lɛk "ɛlpa" we de ɛp di men mɛrɛsin.
Wetin na Tolcapone?
Okay, mek wi put dis simpul wan. Pakinsin sik kin kam we di kεmεkal we dεn kכl dopamin na wi bren dכn dכn. Di mɛrɛsin we dɛn gi yu, we dɛn kɔl levodopa-carbidopa, de wok bay we i de go insay di bren ɛn chenj am to dopamine. Bɔt sɔntɛnde, di we aw dis mɛrɛsin de wok kin go dɔŋ smɔl smɔl.
dis na di say we tolcapone de kam in. Tolcapone na wan dכg we de insay wan klas dεm we dεn kכl COMT inhibito dεm. I de wok bay we i de stɔp di bɔdi fɔ brok di lɛvodopa bifo i rich na di bren. Dis min se i kin mek mɔ pan yu men mɛrɛsin dɛn rich na di bren, ɛn dis kin mek i wok fayn ɛn i kin de fɔ lɔng tɛm . Di brand nem fɔ dis drɔg na Tasmar.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin
Bifo yu bigin fɔ tek dis mɛrɛsin, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt yu kɔmplit wɛlbɔdi kɔndishɔn. Dis mεdikeshכn kin intarakt wit sɔm mεdikal kכndyushכn dεm. If yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl yu dɔktɔ.
| Wɛlbɔdi kɔndishɔn/fakt | Wetin mek yu nid fɔ tɛl di dɔktɔ? |
|---|---|
| Liva sik | Dis mɛrɛsin kin afɛkt di liva, so i impɔtant fɔ no if ɛni liva wik. |
| Kidni sik | Di kidni dɛn kin pul di mɛrɛsin dɛn na di bɔdi. So, di dɔktɔ fɔ no aw di kidni dɛn de wok. |
| Sik we pɔsin kin gɛt na in maynd | Sɔmtɛm dɛn mɛrɛsin ya kin afɛkt yu maynd, so i impɔtant fɔ no bɔt dis bifo tɛm. |
| Slip apnea ɔ narkolepsi | Dis mɛrɛsin kin mek sɔm pipul dɛn slip wantɛm wantɛm, so i impɔtant fɔ ripɔt ɛni kayn tin. |
| If yu de tray fɔ gɛt bɛlɛ, yu gɛt bɛlɛ, ɔ yu na mama we de gi pikin in bɛlɛ | Mek shɔ se yu tɔk bɔt dis, bikɔs yu nid fɔ tek tɛm mɔ fɔ yuz mɛrɛsin pan dɛn kayn tin ya. |
| Alɛji to ɔda mɛrɛsin, it, ɔ day | Tɛl yu dɔktɔ bɔt ɛni alɛji we yu gɛt. |
Aw ɛksaktɔli yu kin yuz dis mɛrɛsin?
Di we aw dɛn kin yuz dis mɛrɛsin rili simpul.
- Swɛla di pil wit wan glas wata.
- Tek di doz we dɛn tɛl yu fɔ tek di tɛm we yu tɛl yu, lɛk aw di dɔktɔ tɛl yu. Yu kin tek am bifo ɔ afta yu it.
- Nɔ ɛva tek pas wetin di dɔktɔ tɛl yu fɔ tek.
- Nɔ stɔp fɔ tek di mɛrɛsin wantɛm wantɛm if yu nɔ gɛt dɔktɔ advays. If yu du dat, dat kin mek yu fil bad bad wan.
- If yu de gi pikin dɛn dis mɛrɛsin, tɔk to dɔktɔ we de mɛn pikin dɛn bɔt am.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu fɔgɛt fɔ tek wan doz, tek am jɔs lɛk aw yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek tu dos wan tɛm.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek mɔ mɛrɛsin pas aw yu tink, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm. Ɔ go na di Imejɛnsi Dipatmɛnt (ETU) na di ɔspitul we de nia yu. Trit dis lɛk se na imejensi.
Mɛmba se na fɔ yu nɔmɔ dɛn dɔn gi dis mɛrɛsin. Nɔ gi am to ɔda pɔsin, ilɛksɛf dɛn gɛt di sem sayn dɛn we yu gɛt.
Ɔda mɛrɛsin dɛm wae kin miks wit dis mɛrɛsin
I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, lɛk vaytamɛn ɛn ɛbul prɔdak dɛm, bikɔs sɔm mɛrɛsin kin miks wit tolcapone.
| Wetin kin mek wi gɛt prɔblɛm? | Tɔk bɔt |
|---|---|
| Nɔ tek dɛn tin ya wit ɛnitin. | |
| MAOI tayp mɛrɛsin dɛn | Mɛrɛsin fɔ pwɛl hat lɛk Marplan, Nardil, ɛn Parnate. |
| Tɛl yu dɔktɔ if yu de tek dɛn tin ya togɛda. | |
| Rum | Rɔm kin chenj di tin dɛn we mɛrɛsin kin du ɛn i kin mek pɔsin slip mɔ. |
| Mɛrɛsin fɔ slip ɔ fɔ wɔri | I kin mek pɔsin slip ɛn nɔ pe atɛnshɔn igen. |
| Apomɔfin, dobutamin, dopamin, ɛpinefrin, isoprotɛrnɔl, norɛpinɛfrin | Dis na mɛrɛsin wae dɛn kin gi fɔ sik dɛm lɛk at sik ɛn ay blɔd prɛshɔn. |
| Warfarin we dɛn kɔl Warfarin | Wan mɛrɛsin we dɛn kin gi fɔ mek blɔd nɔ klɔt. |
| Ɔda | Desipramin, linezolid, methyldopa, nakotik pen kil. |
Us tin dɛn yu fɔ tek tɛm wit we yu de tek mɛrɛsin?
I rili impɔtant fɔ pe atɛnshɔn to di chenj dɛn we de apin na yu bɔdi we yu de tek dis mɛrɛsin.
- Diziz ɛn balans : YuYu kin fil lɛk se yu ed de tɔn ɔ yu nɔ gɛt bɛtɛ ed. So , nɔ drayv ɔ yuz mashin te yu no aw dis mɛrɛsin de afɛkt yu. Tek tɛm we yu de grap we yu sidɔm, mɔ if yu dɔn ol.
- Fɔ slip wantɛm wantɛm: Dis kin rili siriɔs smɔl. Sɔm pipul dɛn kin slip wantɛm wantɛm we dɛn nɔ kin slip, we dɛn de tɔk, it, ɔ ivin drayv. If yu gɛt dis, tɛl yu dɔktɔ wantɛm wantɛm.
- Di tin dɛn we pɔsin kin want fɔ du we i nɔ ebul fɔ kɔntrol: Sɔm pipul dɛn kin want fɔ du mami ɛn dadi biznɛs wit ɔda pɔsin, fɔ du mami ɛn dadi biznɛs wit ɔda pɔsin, fɔ spɛn mɔni we i nɔ nid, ɔ fɔ it pasmak we dɛn de tek dis mɛrɛsin. Dis nɔto natin fɔ shem, ɛn i kin bi wan sayd ɛfɛkt fɔ di mɛrɛsin. If yu gɛt ɛni wan pan dɛn tin ya, tɛl yu dɔktɔ wantɛm wantɛm.
- Kia fɔ yu skin: We yu de tek dis mɛrɛsin, chɛk yu skin ɔltɛm fɔ si if yu gɛt chenj dɛn na yu mɔl dɛn we yu dɔn gɛt ɔ nyu mol dɛn. If yu notis ɛni chenj, tɛl yu dɔktɔ .
- Dray mɔt : If yu mɔt dray, fɔ it gɔm we nɔ gɛt shuga, fɔ sok kandy we nɔ swit, ɛn fɔ drink bɔku wata kin ɛp.
Us sayd ɛfɛkt dɛn we a go gɛt?
Lɛk ɛni mɛrɛsin, tolcapone kin gɛt sayd ɛfɛkt. Sɔm siriɔs, sɔm kɔmɔn.
| Di sayn dɛm we de sho se di liva dɔn pwɛl | Dak yɔlɔ ɔ brawn urine, yu yay ɔ skin de yɔlɔ, pen na di ɔp rayt pat na di bɛlɛ, nɔs, yu nɔ de want fɔ it. |
| Di sayn dɛn we de sho se di mɔsul dɛn dɔn pwɛl | Dak urine, i nɔ izi fɔ pis, wik we nɔ kɔmɔn, mɔsul dɛn de pen. |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip ɔ tong. |
| Ɔda siriɔs sayn dɛn | Sivɛri dayarɛa, hallucinations, slip wan wan, lɔs kɔnshɛns ɛn fɔdɔm, shek we yu nɔ ebul kɔntrol fɔ shek yu an ɛn fut lɛk an, leg, fes, ɛn nɛk. |
| Rɔnbɛlɛ | Diziz we pɔsin kin gɛt |
| Ed de at | I nɔ kin want fɔ it igen |
| Vɔmit | Trobul fɔ slip |
Usay yu kin kip di mɛrɛsin?
- Kip am usay pikin dɛn nɔ go ebul fɔ rich .
- Stɔr na rum tɛmpracha (bitwin 20-25 digri sɛlshiɔs).
- Kip di bɔtul kap tayt tayt wan.
- Trowe ɛni mɛrɛsin we lɛf afta di de we i fɔ dɔn.
Mɛsej we dɛn kin kɛr go na os
- Tolcapone na wan kɔmpin drɔg wae de mek yu men mɛrɛsin fɔ Pakinson woke fayn fayn wan.
- Bifo yu bigin dis mɛrɛsin, tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu gɛt ɛn ɔl di mɛrɛsin dɛn we yu de tek.
- Nɔ stɔp fɔ tek di mɛrɛsin wantɛm wantɛm if yu nɔ gɛt dɔktɔ advays.
- Yu fɔ de wach fɔ slip wantɛm wantɛm, yu nɔ go ebul fɔ kɔntrol yu, ɛn yu go gɛt sayn dɛn we de sho se yu liva dɔn pwɛl. If yu notis ɛni wan pan dɛn tin ya, tɛl yu dɔktɔ wantɛm wantɛm.
- If yu tink se yu dɔn tek am pasmak, go wantɛm wantɛm na di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta ɔ di ɔspitul Imejɛnsi Dipatmɛnt (ETU) we de nia yu.
- Tɔk opin wan wit yu dɔktɔ bɔt ɛni kwɛstyɔn ɔ tin we de mɔna yu.
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