Yu kin imajin se di blɔd vesel dɛn we de kɛr blɔd kɔmɔt na wi at to wi lɔng de smɔl smɔl, ɛn dis kin mek di blɔd prɛshɔn go ɔp bad bad wan? I tan lɛk se yu de swɛt wata paip ɛn di spid we di wata de spid de go ɔp. Dis na wetin wi kin kɔl ‘ Pulmonary Arterial Hypertension’ ɔ ‘PAH’ na mɛrɛsin. Dis na sik we difrɛn smɔl frɔm di nɔmal ay blɔd prɛshɔn ɛn i nid spɛshal atɛnshɔn. Dis kin mek yu gɛt sɔm kayn sik lɛk wae yu nɔr de blo fayn, yu de fil pen na yu chɛst, ɛn yu taya pasmak. So tide wi go tɔk bɔt wan spɛshal mɛrɛsin we dɛn kin yuz fɔ trit dis sik, we na di Treprostinil injɛkshɔn.
Us kayn mɛrɛsin na Treprostinil?
Fɔ tɔk am simpul wan, Treprostinil (brand nem: Remodulin) na wan mɛrɛsin we dɛn kin gi pipul dɛn we gɛt di pulmonary arterial hypertension (PAH) we a bin dɔn tɔk bɔt. Dis drɔg de wok bay we i de mek di blɔd vesel dɛn we dɔn smɔl, big smɔl, ɛn i de mek i izi fɔ mek blɔd flɔ. Dis kin ridyus di wok we de na di at ɛn ɛp fɔ kɔntrol di sayn dɛm. I de mek am izi bak fɔ du tin dɛn we pɔsin kin du ɛvride. Dis na wan rili impɔtant mɛrɛsin wae de ɛp fɔ mek pɔrsin in layf bɛtɛ.
Yu dɔktɔ kin gi yu dis mɛrɛsin bak fɔ ɔda sik dɛn, so if yu gɛt ɛni kwɛstyɔn bɔt dis, mek shɔ se yu aks yu dɔktɔ.
Tin dɛm fɔ tɛl yu dɔktɔ bifo yu bigin dis mɛrɛsin
Bifo yu bigin dis mɛrɛsin, i rili impɔtant fɔ gi yu dɔktɔ kɔmplit diskripshɔn bɔt yu wɛlbɔdi kɔndishɔn. Mek shɔ se yu tɔk mɔ bɔt dɛn tin ya:
- Kidni sik: If yu gɛt ɛni sik we gɛt fɔ du wit di kidni.
- Liva sik: If ɛni prɔblɛm de wit di liva fɔ wok.
- Alɛji: Mek shɔ se yu tɛl yu dɔktɔ if yu dɔn gɛt alɛji fɔ Treprostinil, Epoprostenol, ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- Bɛlɛ: If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ, yu fɔ tɔk to yu dɔktɔ bifo yu bigin dis mɛrɛsin.
Aw a fɔ yuz dis mɛrɛsin?
Dis nɔ tan lɛk pil ɔ kapsul we wi kin tek. di Treprostinil injεkshכn dεn de gi yu insay yu bכdi tru wan sכmכl pכmp we de rכn כltεm (kכntinyu infushכn) . di mεdisin de go insay yu bכdi tru wan tin tכb, we dεn kכl kateta, we kכnekt to dis pכmp. Wi kin du dis tu we dɛn:
1. Sabkutan: Dɛn kin put di kateshɔn ɔnda di skin ɛn gi di mɛrɛsin.
2. Tru wan vein (Intravenous): .Dɛn kin put di kateshɔn dairekt insay wan blɔd vesel (vein) ɛn dɛn kin gi di mɛrɛsin.
Dɛn go gi yu rili gud trenin na di ɔspitul bɔt aw fɔ yuz dis, aw fɔ pripia di pɔmp, ɛn aw fɔ put di kateshɔn insay. I rili impɔtant fɔ fala di instrɔkshɔn dɛn we di dɔktɔ ɛn di wan dɛn we de wok na di nɔs dɛn gi yu di rayt we .
I rili impɔtant: Nɔ stɔp fɔ tek dis mɛrɛsin fɔ ɛni rizin we yu nɔ go to yu mɛdikal tim. If yu stɔp am wantɛm wantɛm, dat kin mek yu sik wɔs.
Wetin yu kin du wit nidul ɛn sirinj we yu dɔn yuz?
Nɔ ɛva trowe nidul ɛn sirinj dɛn we yu dɔn yuz na di dɔti. Dɛn fɔ put dɛn na spɛshal kɔntena (shap kɔntena) we dɛn gi. If yu nɔ gɛt wan, aks yu dɔktɔ ɔ ɔspitul fɔ wan.
Yu tink se dɛn fɔ gi pikin dɛn dis mɛrɛsin?
Pikin dɛn kin nid spɛshal kia we dɛn de gi dis mɛrɛsin, so i impɔtant fɔ tɔk bɔt dis wit dɔktɔ we de mɛn pikin dɛn fɔ advays.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek bɔku mɛrɛsin, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm . Ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Ɔda mɛrɛsin dɛm wae kin miks wit dis mɛrɛsin (Drug Interactions) .
Ɔda mɛrɛsin dɛn we yu de tek kin intarakt wit Treprostinil, so tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn, ɛbul mɛrɛsin, ɛn sɔpɔtmɛnt).
| Di kayn drɔg we dɛn kin yuz | Tin dɛn we yu fɔ wach bɔt |
|---|---|
| Sɔm mɛrɛsin fɔ ay blɔd prɛshɔn | We dɛn put dɛn tin ya togɛda wit Treprostinil, blɔd prɛshɔn kin go dɔŋ tumɔs. |
| Antikoagulant we de mek pɔsin rɔtin | Ɛgzampul dɛn: Mɛdisin dɛn lɛk Warfarin, Enoxaparin, Dabigatran, Apixaban. Dɛn tin ya kin mek yu gɛt mɔ blɔd. |
| Diuretiks we dɛn kin yuz fɔ pul wata | I kin mek yu blɔd prɛshɔn go dɔŋ. |
| Ɔda mɛrɛsin dɛn | Drug dɛm lɛk Gemfibrozil ɛn Rifampin kin afɛkt di wok we dis mɛrɛsin de du. |
Tin dɛn we yu fɔ mɛmba we yu de tek mɛrɛsin
- Chek-ap ɔltɛm: Yu fɔ de tɔk to yu dɔktɔ ɔltɛm fɔ wach aw yu sik de go bifo. Go na klinik dɛn ɔltɛm.
- Skin we de rawnd di kateshɔn: Chɛk di skin we de rawnd di kateshɔn ɔltɛm. If yu gɛt rɛd rɛd, pen, swel, ɔ dischaj we tan lɛk pus, tɛl yu wɛlbɔdi tim wantɛm wantɛm. Dis kin bi sayn fɔ se yu gɛt di sik.
- If yu sik de wɔs: Sɔmtɛm yu sik kin wɔs ivin afta yu dɔn tek dis mɛrɛsin. If yu fil dis kayn we, lɛk if i nɔ izi fɔ yu fɔ blo ɔ yu de fil pen na yu chɛst, kɔl yu dɔktɔ wantɛm wantɛm. Yu doz kin nid fɔ chenj.
Sayd ɛfɛkt dɛn we kin apin bikɔs ɔf mɛrɛsin
Lɛk ɛni mɛrɛsin, Treprostinil kin mek yu gɛt sayd ɛfɛkt. Sɔm pan dɛn tin ya siriɔs, ɛn ɔda wan dɛn kin kɔmɔn.
| Klasifikɛshɔn fɔ di sayd ɛfɛkt dɛn | |
|---|---|
| Sayd ɛfɛkt dɛn we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
| Alɛji riakshɔn lɛk skin rash, it, ayv | We yu fes, yu lip, ɔ yu tɔng swel |
| I nɔ kin izi fɔ yu fɔ blo | Chɛst de pen |
| At nɔ de bit fast, i de bit, ɔ i nɔ de bit ɔltɛm | Nɔs, diziz, ɛn fɔdɔm |
| Fiva ɔ fil kol | Brus, pen, ɔ swel na di say we dɛn injekt am |
| Pen, swɛt, ɔr nɔr de fil fayn na yu an ɛn fut | Wik ɔ taya we nɔ kɔmɔn |
| Sayd ɛfɛkt dɛn we nɔ kin siriɔs, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Bon ɔ jaw pen | Rɔnbɛlɛ |
| Fɔ mek yu flash | Ed de at |
| Nɔs, fɔ vɔmit | |
Aw fɔ kip mɛrɛsin?
Fɔ mek di mɛrɛsin kɔntinyu fɔ gɛt di kwaliti, i rili impɔtant fɔ kip am fayn fayn wan.
- Kip fa frɔm pikin ɛn animal dɛn we yu de mɛn.
- Vayl dɛn we nɔ opin: Stɔr am na di tɛmpracha bitwin 15 ɛn 25 digri sɛlshiɔs.
- Afta yu opin wan vayl: Afta dɛn dɔn tek di fɔs doz fɔ mɛrɛsin, dɛn fɔ yuz di vayl insay 30 dez.
- Di mɛrɛsin we dɔn pas: Nɔ yuz am fɔ ɛni rizin afta di de we i dɔn dɔn.
- Di mɛrɛsin dɛn we de insay di pɔmp:
- If dɛn gi am ɔnda di bɔdi: Dɛn kin yuz di mɛrɛsin we de insay wan sirinj fɔ te 72 awa. Afta 72 awa, trowe di mɛrɛsin we lɛf.
- If dɛn gi am insay di bɛlɛ: Dɛn kin yuz di mɛrɛsin we de insay wan sirinj fɔ te 48 awa. Trowe di mɛrɛsin we lɛf afta 48 awa.
Mɛsej we dɛn kin kɛr go na os
- Treprostinil na wan impɔtant mɛrɛsin fɔ kɔntrol di pulmonary arterial hypertension (PAH). Yu fɔ yuz am jɔs lɛk aw yu dɔktɔ tɛl yu.
- Bifo yu bigin dis mɛrɛsin, tɛl yu dɔktɔ bɔt ɔl yu mɛrɛsin ɛn ɔl di ɔda mɛrɛsin dɛn we yu de tek.
- Nɔ stɔp fɔ tek yu mɛrɛsin we yu nɔ gɛt dɔktɔ advays fɔ ɛni rizin. I kin rili denja.
- Ɔltɛm, de wach fɔ siriɔs sayd ɛfɛkt lɛk fɔ rɛd, pen, ɛn swel na di say we dɛn injekt, ɛn bak fɔ pen na yu chɛst ɛn i nɔ izi fɔ blo. If yu notis ɛni wan pan dɛn tin ya, tɛl yu dɔktɔ wantɛm wantɛm.
- I rili impɔtant fɔ kip di mɛrɛsin fayn ɛn trowe di nidul dɛn we yu dɔn yuz fayn fayn wan.
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