Tide wi go tɔk bɔt wan spɛshal mɛrɛsin we dɛn kin gi pɔsin we de fɛt kansa. Yu ɔ pɔsin we yu sabi go dɔn gi yu dis mɛrɛsin, we dɛn kɔl Vemurafenib , frɔm yu dɔktɔ. So, tide wi go tɔk ditayli bɔt us kayn mɛrɛsin dis, aw dɛn kin yuz am ɛksaktɔli, ɛn wetin wi nid fɔ tek tɛm mɔ bɔt.
Wetin na dis mɛrɛsin we dɛn kɔl Vemurafenib?
Fɔ tɔk am simpul wan, Vemurafenib na wan mɛrɛsin we de tɔch sɔm prɔtin dɛn we de insay di kansa sɛl dɛn ɛn stɔp dɛn fɔ gro. Fɔ tɔk di kɔrɛkt tin, i kin wok lɛk tritmɛnt we dɛn kin yuz fɔ mɛn pipul dɛn . Dɛn kin yuz am mɔ fɔ mɛn wan kayn kansa na di skin we dɛn kɔl melanoma . Dɛn kin yuz am bak fɔ mɛn wan sik we nɔ kin apin so ɔltɛm we dɛn kɔl Ɛrdheim-Chester disease .
Mɛmba se sɔmtɛm, dɔktɔ dɛn kin yuz dis mɛrɛsin fɔ ɔda sik dɛn, so if yu gɛt ɛni kwɛstyɔn, i go fayn fɔ aks yu dɔktɔ ɔ fama.
Di mɔs kɔmɔn brand nem fɔ dis mɛrɛsin na Zelboraf .
Wetin na di tin dɛm we a nid fɔ tɛl di dɔktɔ bifo a bigin dis mɛrɛsin?
Bifo yu bigin fɔ tek Vemurafenib, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt yu wɛlbɔdi istri. I impɔtant mɔ fɔ tɛl yu dɔktɔ if yu gɛt ɛni wan pan dɛn tin ya:
- If yu gɛt ay sik ɔ yu gɛt prɔblɛm wit yu yay
- If yu gɛt at sik
- If yu dɔn gɛt at bit we nɔ de bit ɔltɛm
- If dɛn bin dɔn no se yu gɛt smɔl kalsiɔm, magnɛsiɔm, ɔ potashɔm na yu blɔd
- If yu gɛt sik na yu kidni
- If yu gɛt liva sik
- If yu jɔs dɔn gɛt ɔ yu de du redyushɔn tɛrapi naw
- If yu bin dɔn gɛt alɛji ɔ riakshɔn we nɔ kɔmɔn fɔ Vemurafenib, ɔda mɛrɛsin, it, day, ɔ tin dɛn we de mek yu nɔ pwɛl.
- If yu de tray fɔ gɛt bɛlɛ ɔ yu gɛt bɛlɛ naw (dis rili impɔtant) .
- If yu na mama we de gi pikin in bɛlɛ (dis impɔtant bak) .
Na we di dɔktɔ tɛl yu dɛn tin ya kɔrɛkt wan, i go ebul fɔ disayd if dis mɛrɛsin fayn fɔ yu ɔ nɔ fayn fɔ yu, ɛn us tin dɛn fɔ tek tɛm wit yu.
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
Dis mɛrɛsin kin kam lɛk tablɛt. Yu fɔ tek am wit yu mɔt wit wan glas wata. Fɔ fala di instrɔkshɔn dɛn we de na di prɛskrishɔn lɛbl we yu dɔktɔ ɔ fama gi yu.
- Nɔ brok, krɔs, ɔ chew dɛn tablɛt ya. Swɛla di tablɛt ɔl.
- Yu kin tek dis wit it ɔ yu nɔ it am. Bɔt if yu fil se yu bɛlɛ de pwɛl, i bɛtɛ fɔ tek am wit it.
- Tek di mɛrɛsin di rayt tɛm, na di mɔnt nɔmɔ we yu dɔktɔ tɛl yu fɔ tek. Nɔ tek pas di mɔni we dɛn tɛl yu fɔ tek.
- Di tin we impɔtant pas ɔl na dat, nɔ stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm if yu dɔktɔ nɔ advays yu.
- Bɔku tɛm, dɛn kin tek dɛn mɛrɛsin ya fɔ lɛk 12 awa so. Dat min se if yu tek dɛn na mɔnin, yu fɔ tek di nɛks doz na nɛt.
We yu gɛt yu mɛrɛsin, di famasi go gi yu wan spɛshal gayd buklet (MedGuide) . Rid dis smɔl buk gud gud wan ɛvri tɛm we yu gɛt nyu mɛrɛsin. I gɛt bɔku impɔtant tin dɛn fɔ yu.
If yu de gi pikin dɛn dis mɛrɛsin, yu fɔ tɔk to dɔktɔ we de mɛn pikin dɛn bɔt am ɛn tek spɛshal kia.
Wetin fɔ du if yu tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek dis mɛrɛsin tumɔs bay mistek, kɔl pɔyzin kɔntrol sɛnta ɔ di imejensi rum we de nia yu wantɛm wantɛm.
Dɛn dɔn gi yu dis mɛrɛsin fɔ yu nɔmɔ. Nɔ sheb am wit ɛni ɔda pɔsin.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i nɔ rich 4 awa te yu tek di nɛks doz we yu dɔn sɛtul fɔ tek, skip di doz we yu mis. Bifo dat, tek yu nɛks doz di tɛm we yu dɔn plan fɔ tek. Nɔ ɛva tek dabl doz.
Us ɔda tin dɛn kin miks wit dis mɛrɛsin?
Dis na pɔynt we rili impɔtant. Vemurafenib kin intarakt wit sɔm ɔda mɛrɛsin dɛm wae yu de tek. If dis apin, di sayd ɛfɛkt dɛn kin bɔku ɔ di mɛrɛsin kin wok fayn igen.
Nɔ tek Vemurafenib wit dɛn mɛrɛsin ya:
- Cisapride we dɛn kɔl Cisapride
- Dronedarone we gɛt di sik
- Flukonazɔl we dɛn kɔl
- Pimozayd we dɛn kɔl Pimozide
- Posakonazɔl we dɛn kɔl
- Saquinavir we dɛn kɔl Saquinavir
- Tioridazin we dɛn kɔl Tioridazin
Apat frɔm dat, dɛn mɛrɛsin ya kin miks wit Vemurafenib:
- Antivayrɔs drɔgs fɔ HIV ɔ AIDS
- Tin dɛm wae gɛt kafinɛ (aks yu dɔktɔ bɔt dis) .
- Sɔm antibayɔtiks, fɔ ɛgzampul: klaritromaysin, ɛrythromycin, telithromycin
- Sɔm mɛrɛsin fɔ fungal infɛkshɔn, fɔ ɛgzampul: itraconazole, ketoconazole, voriconazole
- Sɔm mɛrɛsin fɔ di prɔblɛm dɛn we kin mek pɔsin gɛt at ritm
- Sɔm mɛrɛsin dɛm wae dɛn kin yuse fɔ trit kondishɔn lɛk wae yu kin gɛt sik (fit), fɔ ɛgzampul: carbamazepine, phenobarbital, phenytoin
- Sɔm mɛrɛsin dɛn we de mek blɔd nɔ klin ɔ trit am, fɔ ɛgzampul: warfarin
- Dɛkstromɛtɔrfan we dɛn kɔl
- Digoxin we dɛn kin yuz
- Nefazodon we dɛn kɔl Nefazodone
- Midazolam we dɛn kɔl midazolam
- כda mεdisin dεm we kin mek di at ritm we nכ nכmal, i.e. prolong di QT intaval , fכ egzampl: dofetilide, ziprasidone
- Rifabutin we dɛn kɔl
- Rifampin bin de du am
- Rifapentin we dɛn kɔl
- Di ɛbul sɔpɔtmɛnt we dɛn kɔl Sɛnt Jɔn wɔt (Hypericum perforatum) .
- Tizanidin we dɛn kɔl Tizanidine
Dis list nɔ de inklud ɔl di intarakshɔn dɛn. So, tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn (we dɛn gi yu ɛn we yu nɔ de bay na kɔt), ɛbul prɔdak, vaytamɛn, ɛn it we yu de tek. Mek shɔ se yu tɛl yu dɔktɔ if yu de smok, drink rɔm, ɔ yuz drɔgs we nɔ rayt. Dɛn tin ya kin miks bak wit yu mɛrɛsin.
Wetin na de tin wae yu nid fɔ tek tɛm wit mɔr wae yu de tek dis mɛrɛsin?
I rili impɔtant fɔ pe atɛnshɔn to yu wɛlbɔdi ɔltɛm we yu de tek Vemurafenib.
- Si yu dɔktɔ ɔltɛm: Kɔntinyu fɔ chɛk-ap lɛk aw yu dɔktɔ tɛl yu. Yu kin nid bak fɔ mek dɛn du blɔd wok we yu de tek dis mɛrɛsin.
- Siriɔs riakshɔn na di skin: Sɔntɛnde dis mɛrɛsin kin mek pɔsin gɛt siriɔs riakshɔn na di skin. Dɛn tin ya kin apin sɔm wik ɔ mɔnt afta yu bigin fɔ tek di mɛrɛsin. Tɛl yu dɔktɔ wantɛm wantɛm if yu gɛt rash wit sayn dɛm lɛk fiva ɔ kol. Di rash kin tɔn rɛd ɔ pepul, dɔn di blista ɛn di skin kin kɔmɔt. Ɔ yu kin gɛt rɛd rash wit swel na yu fes ɔ yu lip, ɔ yu kin swel limf no dɛm na yu nɛk ɔ yu armpit. If yu notis ɛnitin lɛk dis , tɛl yu dɔktɔ wantɛm wantɛm.
- Tɔk bɔt di risk fɔ gɛt kansa: If yu tek dis mɛrɛsin, yu kin gɛt mɔ risk fɔ gɛt sɔm ɔda kayn kansa. Tɔk to yu dɔktɔ bɔt dis.
- Di chenj we yu de si: If yu notis ɛni chenj na yu yay, lɛk we yu nɔ de si fayn ɔ we yu de si tin difrɛn we pas aw yu kin si am, yu fɔ tɛl yu dɔktɔ wantɛm wantɛm.
- San sɛnsitiviti: Dis na tin bak we rili impɔtant. We yu tek Vemurafenib, yu skin kin rili sɛnsitiv to di san. Dis min se ivin fɔ shɔt tɛm we yu de na di san, i kin mek yu skin bɔn, tɔn rɛd, ɛn blista.
- So, avɔyd di san as yu ebul.
- If yu gɛt fɔ go na di san, .Wear klos we kɔba yu skin fayn fayn wan, wɛr hat we gɛt wayd brim, ɛn yuz gud sanskrin we yu dɔktɔ tɛl yu fɔ du.
- Nɔ yuz san lamp ɔ tanning bed/booth.
- Bɛlɛ ɛn pikin we de gi pikin milk:
- Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 2 wik afta yu dɔn stɔp di mɛrɛsin.
- If yu de plan fɔ gɛt bɛlɛ ɔ yu tink se yu go gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm. Dis mɛrɛsin kin ambɔg di pikin we nɔ bɔn yet bad bad wan. Aks yu dɔktɔ ɔ fama fɔ no mɔ.
- Nɔ gi yu pikin in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 2 wik afta yu dɔn stɔp di mɛrɛsin.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, Vemurafenib kin mek sɔm sayd ɛfɛkt. Sɔm siriɔs, sɔm nɔ so siriɔs.
Di sayd ɛfɛkt dɛm wae yu fɔ ripɔt to yu dɔktɔ ɔr wɛl bɔdi biznɛs kwik kwik wan:
If yu gɛt ɛni wan pan dɛn sik ya, tɛl yu dɔktɔ we yu nɔ go te:
- Alɛji riakshɔn: skin de rɔsh, it ɔ ayv, yu fes, yu lip ɔ yu tɔng de swel
- I nɔ kin izi fɔ yu fɔ blo
- Vishɔn kin chenj
- Urin we gɛt dak kɔlɔ
- Ay pen ɔ swel
- At bit fast ɔ i nɔ de bit ɔltɛm
- Faint, diziz, ɛn fɔdɔm
- Jɛnɛral malaise ɔr simptom dɛm we tan lɛk kol
- Stul dɛn we gɛt layt kɔlɔ
- Fil fɔ it
- Wan nyu wɔt de apia; wan skin we de at ɔ rɛd bɔmp we de blɔd ɔ we nɔ de wɛl; wan chenj na di saiz ɔ kɔlɔ fɔ wan wɔt ɔ spat
- Pen, swɛt, ɔr nɔr de fil fayn na di an ɛn fut
- Rash, fiva, ɛn swel na di bɔdi
- di skin de rεd, blista, di skin de kכl (inklud di skin we de kכl insay di mכt) .
- Pen na di ɔp rayt say na di bɛlɛ
- San sɛnsitiviti ɔ san bɔn
- di skin we de na di an ɛn di fut dɛn we de tik
- Finga dɛn bɛn insay ɛn stif
- Fɔ fil wik ɔ taya we nɔ kɔmɔn
- Fɔ vɔmit
- Di yay ɔ di skin we de yɔlɔ
Sayd ɛfɛkt dɛm wae nɔr kin nid fɔ go to dɔktɔ (tɛl yu dɔktɔ if dɛn tin ya de kɔntinyu ɔr de mɔna yu):
- Test de chenj
- I nɔ kin want fɔ it igen
- Dayarɛa (bɛlɛ de at) .
- Diziz we pɔsin kin gɛt
- Dray skin
- Di ia we de lɔs
- Ed de at
- Pen na di jɔyn dɛn
- Mɔsul dɛn kin pen
- Nɔs (fɔ fil se yu sik) .
- Swel na di ankles, fut, an
- Taya
Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn we pɔsin kin gɛt. If yu gɛt ɛni ɔda sayn we nɔ kɔmɔn, go to yu dɔktɔ. If yu want, yu kin ripɔt di sayd ɛfɛkt dɛn bak to di FDA (Food and Drug Administration) bay we yu kɔl 1-800-FDA-1088.
Aw a fɔ kip dɛn pils ya?
- Kip am usay pikin dɛn nɔ go ebul fɔ rich. Dis rili impɔtant.
- Stɔr na rum tɛmpracha (bitwin 20 ɛn 25 digri sɛlshiɔs / 68 ɛn 77 digri Fahrenheit).
- Kip di mɛrɛsin insay di ɔrijinal bɔtul we i kam insay, tayt tayt wan.
- Trowe di mɛrɛsin we dɔn pas ɛn yu nɔ yuz am.
Fɔ dɔn, tin dɛn we yu nid fɔ mɛmba (Take-Home Message) .
Vemurafenib na wan mɛrɛsin we de ple impɔtant pat pan kansa tritmɛnt. Sɔm tin dɛn de we yu fɔ no we yu de yuz am.
- Fɔ fala di dɔktɔ in instrɔkshɔn dɛn di rayt we. Du ɔltin jɔs lɛk aw i tɛl yu, ivin ustɛm fɔ tek di mɛrɛsin, di mɔni, ɛn aw fɔ stɔp fɔ tek am.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek ɛn ɛni ɔda sik we yu gɛt. Dis go ɛp fɔ mek yu nɔ gɛt di sayd ɛfɛkt dɛn.
- If yu notis ɛni nyu sayn, mɔ di skin chenj ɔ chenj na yu yay, tɛl yu dɔktɔ we nɔ go te.
- Tek tɛm wit di san. Nɔ fɔgɛt dis.
- If yu gɛt bɛlɛ, yu de plan fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ, mek shɔ se yu tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin.
Dis atikul na jɔs wan jɔnaral sɔmari. If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis mɛrɛsin, duya nɔ shem fɔ aks yu dɔktɔ, fama, ɔ ɔda pɔsin we de kia fɔ yu wɛlbɔdi biznɛs. Dɛn go ebul fɔ ɛp yu.
Wi de wish yu ɔl di bɛst pan yu wɛlbɔdi joyn!
` Vemurafenib, Zelboraf, kansa mɛrɛsin, skin kansa, melanoma, sayd ɛfɛkt, mɛrɛsin, kansa tritmɛnt
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