Bɔku tɛm yu kin gɛt bɛlɛ ɔlsa ɔ gastritis? Yu de sɔfa wit ɔlsa na yu bɛlɛ we nɔ de chenj ɛn we nɔ de bɛtɛ pan ɔl we yu de trit yu? Yu gɛt dayarɛa bak? Sɔmtɛm wi kin tink bɔt dɛn tin ya as nɔmal tin, bɔt tide wi go tɔk bɔt wan kayn tin we nɔ kin apin so ɔltɛm we kin ayd biɛn dɛn tin ya, bɔt kin siriɔs smɔl. Dɛn kɔl dis sik we dɛn kɔl Zollinger-Ellison Syndrome.
Fɔ tɔk am simpul wan, wetin na Zollinger-Ellison Syndrome (ZES)?
Imajin se wan swich de na wi bɛlɛ we de kɔntrol di we aw asid de mek. Wan ɔmon we dɛn kɔl gastrin de wok lɛk da switch de. Nɔmal wan, we wi de it, dis ɔmon de kɔmɔt, we de mek di bɛlɛ de mek asid fɔ ɛp fɔ dayjɛst di it. We dɛn dɔn di wok, dɛn kin kɔntrol di asid we dɛn de mek.
Bɔt pan pipul dɛn we gɛt Zollinger-Ellison Syndrome (ZES), wan kayn tumbu we dɛn kɔl gastrinoma kin kam na dɛn bɔdi. dis tכmכro dεm kin divεlכp bכku tεm na di pankrias כ di כp pat pan di sכmכl intestin (duodenum). wetin dεn tכmכro dεm ya de du na fכ mek tu mכch כmon gastrin we nכ de kכntrכl. I tan lɛk se di switch de ‘on’ ɔltɛm.
We wi gɛt tumɔs gastrin, wi bɛlɛ kin bigin fɔ mek tumɔs asid. Dis asid we pasmak na in de mek yu gɛt siriɔs bɛlɛ ɔlsa (pɛptik ɔlsa) ɛn dayarɛa we nɔ de dɔn.
Na lɛk 60% pan dɛn gastrinomas ya kin bi kansa , so i rili impɔtant fɔ no ɛn trit dɛn kwik kwik wan.
Wetin na di sayn dɛm fɔ dis sik? Aw wi go no?
Sɔntɛnde, ZES nɔ kin sho ɛni sayn na di fɔs stej. Bɔt we di sayn dɛn de sho, dɛn kin tranga smɔl pas di gastritis we dɛn kin gɛt ɔltɛm. Di kayn we aw di sik kin tranga kin difrɛn difrɛn wan bay di sayz ɛn di nɔmba fɔ di tumbu dɛn na yu bɔdi.
Lɛ wi ɛksplen dis mɔ na di tebul we de dɔŋ ya.
| Di sayn we de sho se di sik de | Wan simpul ɛksplen |
|---|---|
| Bɛlɛ pen bad bad wan ɔ blo | dis pen kin apin we di wכl dεm na di bεlε εn di intestin dεm dεn dכn pwεl bay di bכdi asid we pasmak. |
| Dayarɛa we nɔ de dɔn | we di asid we pasmak go insay di intestinal, i de ambɔg di wok we di εnzym dεm we de de de wok, we de mek yu gεt dayariya εn it nכ de digεst fayn. |
| Vɔmit ɔ pas blɔd na di stɔl | Dis na wetin kin apin we yu de blɔd bikɔs ɔf ɔlsa na di bɛlɛ. Vɔmit kin blak lɛk kɔfi grɔn ɔ stɔl kin blak lɛk tar. |
| Stul dɛn we gɛt ɔyl ɛn we de flɔt | we di fεt we de digεst nכ de wok fayn biכs fכ di asid we pasmak, di fεt we dεn nכ daygεst de kכmכt na di stכl. |
| At we kin bɔn ɔltɛm | dis kכndyushכn de apin bikoz fכ di εksyכs bכdi asid we de muv כp insay di εsophagus (asid rεfluks). |
| Anorexia ɛn we yu de lɔs yu wet | Pen ɔltɛm ɛn prɔblɛm wit di we aw yu de digest kin mek yu nɔ want fɔ it ɛn yu nɔ go gɛt bɔku bɔku bɔdi. |
| Taya ɛn wik | As yu bɛlɛ wund dɛn de blɔd smɔl smɔl, yu kin fil taya bikɔs yu nɔ gɛt blɔd. |
Sɔntɛnde, if dɛn tumbu ya skata to di liva (metastasis) , dɛn kin sho bak sayn dɛm fɔ kansa na di liva. Fɔ ɛgzampul, yu kin it, yu yay ɛn yu skin kin yɔlɔ (jaundice).
Wetin mek sɔntin lɛk dis kin apin?
Mɔs tɛm, ZES kin apin wan wan tɛm , we min se i jɔs kin apin.
Bɔt lɛk 25% pan di sik pipul dɛn kin gɛt dis sik we dɛn kɔl MEN Tayp 1 (Multiple Endocrine Neoplasia Type 1).Wit wan jenɛtik kɔndishɔn we dɛn kɔl ZES. Fɔ tɔk am simpul wan, dis na tin we nɔ kin apin we pɔsin kin gɛt we i kam pan jɛnɛtiks. insay dis, risk de fכ tכmכro fכ fכm na sεvεra כmon-prodyuz gland dεm na wi bכdi di sem tεm. ZES na jɔs wan pat pan am.
Us tɛst dɛn kin du fɔ no dis?
If yu gɛt di sayn dɛm wae wi dɔn tɔk bɔt, yu dɔktɔ go ɔda fɔ du sɔm tɛst dɛm if dɛn sɔspɛkt se yu gɛt ZES.
Fɔs tɛst dɛn
- Blɔd Tɛst: Dɛn tin ya de chɛk di lɛvɛl we di ɔmon gastrin de na yu blɔd. If yu gɛt ZES, dis lɛvɛl go ay abnɔmal wan . Dɛn kɔl dis haypagastrinemia.
- tεst di bεlε asid lεvεl: dεn de put wan tכb tru di nos insay di bεlε εn tek sεmpl fכ di asid. insay ZES, dis asid lεvεl de rili hכy.
- Imej Test: Dɛn kin du CT skan ɔ MRI skan fɔ chɛk fɔ si if di tumbu dɛn de na di pankrias ɔ di intestinal.
Fɔda tɛst dɛn if dɛn kɔnfyus di tumbu dɛn
Dɛn de du ɔda tɛst fɔ no ustɛm dɛn tumbu ya de, dɛn saiz, ɛn if dɛn gɛt kansa ɔ nɔ gɛt kansa.
- εndoskopi: dεn kin put wan tin tכb we gεt kεmεra tru di mכt fכ egzamin di bεlε εn di כp pat pan di sכmכl intestin. Dis kin ɛp fɔ si if ɛni bɛlɛ ɔlsa de.
- εndoskopik כltra saund: Dis na we dεn kכmbayn εndoskopi εn כltra saund skan. I kin no ivin smɔl smɔl tumbu dɛn na di pankrias.
- ERCP: Dis na spɛshal skan bak.
- Bayopsi (Fine-needle aspiration): Dɛn kin tek wan rili smɔl tisu frɔm di tumbu ɛn chɛk am ɔnda maykroskɔp fɔ si if i gɛt kansa sɛl dɛn.
Wetin na di tritmɛnt dɛm fɔ dis?
Di tritmɛnt we dɛn kin pik kin dipen pan aw yu sik bad ɛn if di lump gɛt kansa ɔ nɔ gɛt kansa. Tri men tritmɛnt dɛn de we yu kin du.
| Di we aw dɛn kin trit am | Tɔk bɔt |
|---|---|
| Mɛrɛsin we dɛn kin gi | di wan dεm we dεn kin yus pas כl na di protכn pכmp inhibito dεm (PPI dεm).Dis na mεdikeshכn dεm we de kכntrכl di prodyushכn fכ di bεlε asid. Yu kin gɛt fɔ tek dɛn mɛrɛsin ya fɔ di res ɔf yu layf. |
| Ɔpreshɔn | If dɛn kin pul di tumbu, i kin fayn fɔ mek dɛn du ɔpreshɔn. di kayn כpεrayshכn de difrεn dipכnt pan di say we di tכmכro de (e.g., Pancreatectomy - fכ pul pat pan di pankrias, Duodenectomy - fכ pul pat pan di sכmכl intestin). |
| Kansa Tɛrapi | If di tumbu dɛn gɛt kansa ɛn dɛn dɔn skata to ɔda pat dɛn na di bɔdi, dɛn kin gi am tritmɛnt dɛn lɛk kemotɛrapi . Dis kin wok fɔ kɔntrol di we aw di kansa sɛl dɛn de gro ɛn ridyus di sayn dɛm. |
Aw mi fiuja go tan lɛk wit dis sityueshɔn?
Dis na kwɛstyɔn we bɔku pipul dɛn gɛt. Yu fiuja dipen pan di kayn kansa we yu gɛt.
- Tumɔs dɛn we nɔ gɛt kansa: Dɛn tin ya nɔ de mek yu layf de pan denja, bɔt yu go nid fɔ kɔntinyu fɔ tek mɛrɛsin fɔ kɔntrol di asid na yu bɛlɛ.
- Kansa tumor: Di situeshɔn difrɛn smɔl ya. If dɛn ebul fɔ pul ɔl di kansa sɛl dɛn na di bɔdi tru ɔpreshɔn, di sik kin wɛl kpatakpata. Ivin da tɛm de, yu go nid fɔ kɔntinyu fɔ du dɔktɔ tɛst fɔ si if di sik kam bak.
Akɔdin to ɛkspɛkt statystik, pas 90% pan di pasɛnt dɛn we dɛn dɔn ɔpreshɔn ɔl dɛn tumbu dɛn kin liv fɔ 5-10 ia. If ɔpreshɔn nɔ ebul fɔ pul ɔl di tɔŋ dɛm, di 5 ia sɔvayv rɛt na lɛk 43%.
Bɔt mɛmba dis: Dɛn statystik ya na jɔs avɛrej bays pan data frɔm tawzin pasɛnt dɛn. Yu wan wan tin kin difrɛn bad bad wan. So, di bɛst pɔsin fɔ no ustɛm yu sik na di dɔktɔ we de trit yu.
Aw a fɔ kia fɔ misɛf?
If dɛn no se yu gɛt ZES, yu go nid fɔ mek sɔm chenj dɛn na yu layf.
- Tek yu mɛrɛsin kɔrɛkt wan: I impɔtant fɔ tek di mɛrɛsin dɛn we de ridyus di asid (PPI) di rayt tɛm, lɛk aw yu dɔktɔ tɛl yu.
- Dɛn kin chɛk yu ɔltɛm wit dɔktɔ: Ɛspɛshali if yu dɔn gɛt kansa tumbu, yu fɔ go fɔ fala-ɔp chɛk-ap ɔltɛm lɛk aw yu dɔktɔ tɛl yu fɔ si if di sik dɔn kam bak.
- Yu fɔ no bɔt di sayn dɛm: If di sayn dɛm lɛk bɛlɛ pen ɛn dayarɛa kam bak afta yu dɔn trit yu, tɛl yu dɔktɔ wantɛm wantɛm .
E nɔrmal fɔ fil wɔri ɛn frayd wae yu kam fɔ no se yu gɛt dis sik wae nɔr kin bɔrku. Yu gɛt bɔku kwɛstyɔn dɛn. Tɔk to yu dɔktɔ opin wan bɔt dɛn ɔl. Lisin gud wan to yu tɛst rizɔlt ɛn tritmɛnt plan. Dɛn rɛdi ɛn rɛdi fɔ ɛp yu.
Mɛsej we dɛn kin kɛr go na os
- Zollinger-Ellison Syndrome (ZES) na wan sik we nɔ kin apin so ɔltɛm we wan tumbu we dɛn kɔl gastrinoma we kin mek di bɛlɛ asid pasmak.
- Di men sayn dɛm wae gɛt fɔ du wit dis na wae yu kin gɛt ɔlsa na yu bɛlɛ ɔltɛm wae nɔr kin ansa tritmɛnt ɛn yu kin gɛt dayarɛa fɔ lɔng tɛm.
- Dɛn tumbu ya kin bi kansa ɔ nɔ kin bi, so fɔ no am kwik kwik wan rili impɔtant.
- Dɛn kin ebul fɔ kɔntrol dis sik fayn fayn wan wit di rayt mɛrɛsin, ɔpreshɔn, ɛn if nid de, dɛn kin trit kansa.
- If yu gɛt dɛn sik ya, nɔ panik ɛn go to dɔktɔ we sabi du di wok wantɛm wantɛm fɔ advays yu.
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