Ka tuyige ku bajaasi abato mu mubiri gwo - granulocytes.

Ffenna tufuba nnyo okwewala endwadde, si bwe kiri? Oluusi n’omusujja guyinza okutulwaza. Kale, munda mu mibiri gyaffe, waliwo enkola ey’okwekuuma eyeewuunyisa ennyo okulwanyisa endwadde n’endwadde ng’ezo. Ekitundu ekikulu ennyo mu nkola eyo ey’okwekuuma ze granulocytes ze tugenda okwogerako leero. Abantu bano bakolera munda mu mibiri gyaffe ng’abajaasi abakuuma eggwanga lyaffe. Okay, kale ka tulabe granulocytes zino ani, kiki kye zikola, era kiki ekibaawo singa zifuuka ntono oba nnyingi. Buli kimu kyangu.

Omanyi granulocytes kye ki?

Mu ngeri ennyangu, granulocyte kika kya butoffaali obweru. Yee, owulidde nti mu musaayi mulimu obutoffaali obumyufu n’obutoffaali obweru. Mu butoffaali obwo obweru, ekika ekisinga okumanyibwa ye granulocyte.

Zifuna erinnya lyazo kubanga munda mu butoffaali bwazo, mu cytoplasm (amazzi amanene agali munda mu katoffaali), waliwo obutonde obutonotono obulinga ensigo obuyitibwa granules. Munda mu butundutundu buno mulimu eddagala ery’enjawulo, gamba nga enziyiza . Bino bifaanana nga ebyokulwanyisa byabwe.

Teebereza ekintu ng’obuwuka oba obuwuka bwe kiyingira mu mubiri gwo, oba bwe wabaawo okuzimba olw’obuvune, obutoffaali buno obuyitibwa granulocytes bufubutuka okugenda mu kifo ekyo nga ambyulensi eriko ssirensi. Bajja ne bafulumya eddagala eriri munda mu butoffaali bwabwe okulwanyisa obuwuka buno.

Kale, engeri yokka gy’oyinza okumanyamu ddala emiwendo gya granulocyte zo kwe kwekebeza omusaayi. Kino osobola okukikola ne CBC (Complete Blood Count), ekitera okukolebwa.

• If your granulocyte count is high , kiyinza okutegeeza nti waliwo ekika ky’obulwadde mu mubiri gwo.
• Ate era, singa omuwendo gw’obutoffaali obuyitibwa granulocyte guba mutono , kiyinza okuba akabonero k’obulwadde bw’obusimu bw’amagumba , gamba nga leukemia oba aplastic anemia . Naye teweeraliikiriranga, si buli kukendeera nti kya bulabe.

Ensigo zino eziyitibwa granulocytes era ziyitibwa `granular leukocytes`, `polymorphonuclear leukocytes` oba `obutoffaali bwa PMN`. Naye ka tumale tuziyite `granulocytes`.

Kiki ekibaawo singa oba n’obutoffaali obuyitibwa granulocytes obutakuze?

Mu budde obwabulijjo, obutoffaali buno obuyitibwa granulocyte buyingira mu musaayi nga bumaze okukula mu bujjuvu mu busimu bwaffe obw’amagumba, kwe kugamba, nga bumaze okukula. Ng’abaana abali mu ssomero bwe basoma obulungi ne bayita ebigezo, bavaayo.

Kyokka, oluusi obutoffaali buno obutakuze obuyitibwa granulocytes , kwe kugamba, obutoffaali obutakula mu bujjuvu, busangibwa mu musaayi. Waliwo ensonga eziwerako ezisoboka lwaki kino kiyinza okubaawo:

• Ekimu kiri nti wayinza okubaawo obuzibu ku busimu bw’amagumba.
• Oba, kiyinza okuba nti omulambo guddamu okukwatibwa yinfekisoni ku mukisa ogusooka, ng’okusindika amangu abajaasi abapya mu lutalo.

Abasawo batera okweraliikirira katono singa oba olina ebitundu ebisukka mu 2% ku butoffaali bwo obweru bwonna nga granulocytes ezitakuze.

Naye era jjukira kino:

• Bamaama ab’embuto n’abalongo abaakazaalibwa mu butonde bayinza okuba n’obutoffaali obumu obuyitibwa granulocytes obutakuze mu musaayi gwabwe. Kino kya bulijjo, akabonero akalaga nti obusigo bw’amagumba bukola bulungi. Kale tewali kintu kyonna kyeraliikirira.

Omulimu omukulu ogwa granulocytes gwe guliwa?

Granulocytes tezikola zokka. Bakolera wamu nga ttiimu okutulwanyisa n’okutukuuma ebintu nga yinfekisoni, obuwuka, n’ebirungo ebituleetera alergy ebiyingira mu mibiri gyaffe.

Waliwo ebika bina ebikulu ebya granulocytes. Buli kika kirina eddagala n’enziyiza ez’enjawulo katono munda mu butundutundu obwo, n’olwekyo emirimu gyabyo gya njawulo katono.

1. Ebirungo ebiyitibwa Neutrophils

• Kino kye kika kya granulocyte ekisinga obungi , okufaananako ekibinja ekisinga obunene mu ggye.
• Omulabe waabwe omukulu ye bakitiriya . Akatoffaali kamu aka neutrophil kasobola okumira n’okusaanyaawo obuwuka nga 20 mu bulamu bwabwo!
• Neutrophils zikola wakati wa 40% ne 60% ku granulocytes zonna mu mubiri gwaffe, ekitegeeza nga bibiri ku bisatu eby’obutoffaali obweru.

2. Ebirungo ebiyitibwa Eosinophils

• Bino nabyo bikulu nnyo. Zisangibwa kumpi mu bitundu byonna eby'abaserikale b'omubiri .
• Emirimu gyabwe giba mingi naddala mu mbeera z'abalina alergy .
• Ate era, eosinophils zino ze zirwanyisa obuwuka obusirikitu , kwe kugamba, ebiramu ebireeta endwadde ng’ensowera.

3. Ebiwuka ebiyitibwa Basophils

• Abantu bano okusinga kulwanyisa alergy .
• Zifulumya eddagala eriyitibwa histamine , eriyamba omubiri okugoba alergy (kilowoozeeko ng’okusesema n’okukulukuta ennyindo ).
• Era kifulumya heparin , ekiziyiza omusaayi okuzimba.

4. Obutoffaali obuyitibwa mast cells

• Obutoffaali obuyitibwa mast cells nabwo kika kya granulocyte. Naye tezitambula mu musaayi ng’endala. Zibeera munda mu bitundu byaffe eby’omubiri.
• Okufaananako ne basophils, nazo zifulumya histamine ne heparin.
• Basophils ne mast cells zifaanagana mu ndabika. Enjawulo enkulu eri nti basophils zirina obulamu obutono era zifubutuka okugenda mu kifo we zizimba amangu ddala nga zikutte.

Granulocytes zisangibwa wa?

Obujaasi buno obutono obuyitibwa granulocytes bukolebwa mu...Munda mu busimu bw'amagumba . Nga boot camp. Olwo omubiri bwe gwetaaga obuweereza bwagwo, beegatta ku musaayi ne bagenda mu bifo ebituufu.

Omutindo gwa granulocytes ogwa bulijjo gulina okuba gutya?

Mu budde obwabulijjo, omuntu omulamu obulungi alina okuba n’obutoffaali obuyitibwa granulocytes obuli wakati wa 1,500 ne 8,500 buli microliter (akatondo k’omusaayi akatono ennyo) ak’omusaayi. Lipoota yo ey’okukebera omusaayi osanga kino ejja kulaga nga `1.5 – 8.5 x 10^9/L`. Emiwendo gino giyinza okwawukana katono okuva ku laabu okudda ku ndala.

Singa tutwala ebika bya granulocytes eby’enjawulo bye twayogeddeko emabegako ng’ebitundu ku kikumi, kino kye birina okuba mu budde obwa bulijjo:

• Neutrophils: Wakati wa 50% ne 70% ku butoffaali obweru bwonna.
• Eosinophils: Wakati wa 1% ne 3%.
• Basophils: Wakati wa 0.4% ne 1%.

Endwadde ki ezitera okukwata obutoffaali obuyitibwa granulocytes?

Embeera z’obujjanjabi ez’enjawulo ziyinza okubaawo olw’omuwendo gw’obutoffaali obuyitibwa granulocytes okweyongera oba okukendeera. Ka tulabe ebitonotono ku byo:

• Basophilia: Kino kweyongera kw’omuwendo gwa basophils. Kino kiyinza okuba akabonero akalaga nti omuntu alina yinfekisoni, obulwadde bw’abaserikale b’omubiri (obulwadde obutoffaali bw’omubiri bwe bwe bulumbye), oba embeera nga leukemia.
• Cyclic neutropenia: Kino kye kiseera omutindo gwa neutrophils bwe gukendeera ate ne gudda mu mbeera eya bulijjo. Kino kibaawo mu nsengekera. Embeera eno eyongera obulabe bw’okufuna yinfekisoni.
• Eosinophilia: Okweyongera kw’omuwendo gwa eosinophils. Kino kitera okulabibwa mu mbeera nga asima ne alergy ya sizoni . Era kiyinza okuba akabonero k'obulwadde bw'ebiwuka oba endwadde z'abaserikale b'omubiri nga sarcoidosis ne inflammatory bowel disease .
• Granulocytosis: Kino kweyongera mu muwendo gwonna ogwa granulocytes. Kino kiyinza okuba n’ensonga eziwerako. Yinfekisoni, kookolo w’omusaayi, endwadde ezimu ez’abaserikale b’omubiri, n’endwadde z’amagumba ze zisinga.
• Neutropenia (era eyitibwa granulocytopenia): Kino kikendeera mu muwendo gwa granulocytes naddala neutrophils. Kino kitera kuva ku buzibu bw’omusaayi oba mu busimu bw’amagumba, gamba ng’okukendeera kw’omusaayi mu musaayi oba obulwadde bwa leukemia . Agranulocytosis ye ngeri esinga okuba ey’amaanyi mu kukendeera kw’obusimu obuyitibwa neutropenia.

Bubonero ki obutera okulabika ku ndwadde ezeekuusa ku granulocyte?

Obubonero buno buyinza okwawukana okusinziira ku mbeera yo entongole. Kyokka obumu ku bubonero obusinga okulabika mulimu:

• Okuwulira nga okooye buli kiseera (Obukoowu) .
• Omusujja
• Obulwadde obutera okukwatibwa (e.g. omusujja, yinfekisoni mu mumiro, yinfekisoni y’omusulo) .
• Obulwadde bw’ennyindo
• Obulumi mu binywa
• Amabwa mu kamwa
• Okuziyira n’okusiiyibwa
• Ebizimba ku lususu, gamba nga eczema
• Okulumwa mu mamiro
• Ensigo ezizimba (mu bifo ng’ensingo n’enkwawa) .

Bw’osigala ng’olina obubonero buno obumu oba obusingawo, kirungi okugenda ew’omusawo akuwe amagezi.

Bikebere ki ebikolebwa okukebera emiwendo gya granulocyte?

Omusawo asobola okukebera omuwendo gwa granulocyte zo ng’akola okubala omusaayi mu bujjuvu (CBC) . Kino kyangu nnyo okukebera omusaayi ekitera okukolebwa.

Okuzuula emiwendo gya granulocyte ku lipoota yo eya CBC, noonya ebigambo bino:

• Neutrophil oba “neut.”
• Eosinophil oba “eosin.”
• Basophil oba “baso.”

Ebigambo bino bitera okugobererwa ekigambo “abs.” Kino kitegeeza “ekituukiridde.” Kitegeeza omuwendo omutuufu ogwa buli kika ky’obutoffaali (omuwendo omutuufu mu voliyumu y’omusaayi).

Bujjanjabi ki obw’endwadde ezeekuusa ku granulocyte?

Enkola z’obujjanjabi zijja kwawukana okusinziira ku mbeera gy’olimu, naye obujjanjabi obumu obutera okukolebwa mulimu:

• Eddagala eritta obuwuka: Singa wabaawo yinfekisoni.
• Okukyusa obusigo bw’amagumba: Mu mbeera ezimu ez’amaanyi.
• Corticosteroids: Kikendeeza ku kuzimba.
• Empiso za G-CSF (granulocyte colony-stimulating factor): Okwongera ku kukola granulocyte.
• Eddagala eriziyiza obusimu obuziyiza endwadde: Mu ndwadde z’abaserikale b’omubiri.

Singa kookolo akosa obutoffaali obuyitibwa granulocytes, obujjanjabi bw’ayinza okuli:

• Obujjanjabi bw’eddagala
• Obujjanjabi bw’abaserikale b’omubiri
• Obujjanjabi bw’amasannyalaze (radiation therapy).
• Obujjanjabi obugendereddwamu
• Okuloongoosa

Obujjanjabi bw’obutoffaali obuyitibwa granulocytes obutakuze

Singa ebyava mu musaayi gwo biraga nti olina obutoffaali obuyitibwa granulocytes obutakuze, omusawo ayinza okwongera okukebera okuzuula ekivaako.

• Singa ekivaako yinfekisoni, eddagala erituufu lijja kuwandiikibwa.
• Singa ekivaako kiba kintu nga kookolo, bajja kwogera naawe ku ngeri y’obujjanjabi ng’okulongoosa, eddagala oba obujjanjabi obw’amasannyalaze.

Nze nneerabirira ntya? Watya singa mba nneetaaga okweraliikirira emiwendo gyange egya granulocyte?

Bw’oba ​​olina embeera ekosa emiwendo gy’obutoffaali obuyitibwa granulocyte, kikulu okwekuuma obutakwatibwa yinfekisoni. Bino bye bimu ku bintu by’osobola okukola:

• Weewale okukwata ku maaso, ennyindo oba mu maaso nga tonaaba mu ngalo. Obuwuka bumeka obutalabika obuli ku ngalo zaffe?
• Funa okugema okuteesebwako mu budde. Bino bisobola okukuuma yinfekisoni nnyingi.
• Lambula omusawo w’amannyo buli kiseera, era kuuma obuyonjo bw’omu kamwa obulungi awaka. Senya amannyo n’okusiimuula obulungi.
• Naaba engalo enfunda n’enfunda n’obulungi naddala nga tonnalya, ng’omaze okukozesa ekinabiro, n’oluvannyuma lw’okufuluma.
• Weewale ebifo omujjudde abantu n’ebifo abalwadde we babeera nga bwe kisoboka.
• Lya emmere ennungi. Lya nnyo ebibala n’enva endiirwa. Bino binyweza abaserikale b’omubiri.
• Funa otulo otumala.
• Weewale okunywa sigala.

Ekisinga obukulu kwe kufuna amagezi g’omusawo bw’oba ​​olina obubonero bwonna obutali bwa bulijjo, nga tobubuusa maaso.

Njawulo ki eri wakati wa Granulocytes ne Agranulocytes?

Bino byombi bika bya butoffaali obweru. Naye, agranulocytes tezirina bitundutundu ebyogeddwako waggulu mu cytoplasm yazo. Ennukuta "A" etera okutegeeza "nedda." Kale "agranulocyte" kitegeeza ekintu nga "obutoffaali obutaliimu bitundutundu."

Monocytes ne lymphocytes bye byokulabirako bibiri ebya agranulocytes zino. Era zikola kinene nnyo mu baserikale b’omubiri.

N’ekisembayo, ebintu by’olina okujjukira

Granulocytes ze bajaasi abasirise ab’abaserikale baffe abalwanyisa yinfekisoni, alergens, n’ebintu ebirala ebinyiiza ebiyingira mu mibiri gyaffe. Obutoffaali buno obweru bwe buba bukola bulungi, emibiri gyaffe gisobola okwekuuma obulungi.

Wabula singa omubiri gwo tegukola granulocytes zimala, oba singa omuwendo gwa granulocytes guba mutono nnyo oba nga mungi nnyo, kiyinza okulaga nti waliwo embeera ey’amaanyi.

Bw’oba ​​olwala ennyo, ng’otera okukwatibwa yinfekisoni, oba ng’olina obubonero bwonna obwogeddwako waggulu, nsaba olabe omusawo. Basobola okukola ebigezo ebyetaagisa, okuzuula ekivaako, n’okuteekateeka obujjanjabi obusinga obulungi gy’oli. Okufaayo ku bulamu bwo kye kintu ekisinga obukulu!

` Granulocytes, obutoffaali obweru, obutafaali obuziyiza endwadde, yinfekisoni, okukeberebwa omusaayi, obubonero, amagezi ku bulamu, CBC, neutrophils, eosinophils, basophils