Owulidde ku Gleason Score ku kookolo w'enseke? Ka twogere ku nsonga eno!

Omusawo bw’akugamba nti olina kookolo w’enseke, olina okuwulira situleesi n’okweraliikirira kungi, nedda? Mu kiseera ekyo, owulira ku kukeberebwa kw’abasawo okupya n’ebigambo ebimu ebizibu. Oyinza okuwulira, oba oyinza okuba nga wawulira dda, ekigambo kimu ye ‘Gleason Score’. Kale, bw'owulira bino, oyinza okutya n'ogamba nti, "Kiki kino ekipya?" Eno y’ensonga lwaki, leero tugenda kwogera ku Gleason Score eno kyeri, ne ky’eyogera ddala ku mbeera yo, mu ngeri ennyangu gy’osobola okutegeera.

Omanyi Gleason Score kye ki?

Mu ngeri ennyangu, bw’oba ​​olina kookolo w’enseke, Gleason Score ngeri ya kwekenneenya butonde bwa kookolo – bw’afaanana, amangu bw’ayinza okusaasaana, engeri gy’ayinza okuba ey’obukambwe, n’ebirala Kiba ng’okugaba ebigezo mu kigezo mu ssomero, naye kisingako katono ku bya ssaayansi era nga kizibu.

Kino abakugu mu by’endwadde ( abakugu abeekenneenya ebitundu by’omubiri n’okuzuula endwadde) kye bakola nga batunuulira sampuli y’ebitundu byo eby’enseke (akatundu akatono akakwatibwa mu kiseera ky’okukeberebwa) wansi wa microscope okuzuula obutoffaali bwa kookolo bwe bufaanana. Enkola eno ey’okuteeba obubonero eyamba abasawo okuteekateeka obujjanjabi obusinga obulungi gy’oli n’okulagula ku ngeri gy’ogenda okuteeberezaamu oluvannyuma lw’okujjanjabwa.

Gleason Score ebalwa etya?

Okay, kati katutunuulire engeri Gleason Score eno gyekolebwamu. Nga bwe nnagambye emabegako, abakugu mu by’endwadde bakola omulimu guno omukulu. Batunuulira nnyo sampuli z’ebitundu by’omubiri okuva mu prostate yo nga bakozesa microscope. Bw’oba ​​olina kookolo w’enseke, kitegeeza nti obumu ku butoffaali obuli mu nseke yo bukyuse okuva ku butoffaali obwa bulijjo era obulamu ne bufuuka obutoffaali bwa kookolo .

Teebereza, mu biseera ebisooka, obutoffaali buno obwa kookolo buyinza okufaanana ng’obutoffaali obulamu. Just okwefuula. Naye ekiseera bwe kigenda kiyitawo, kookolo bw’agenda akula, endabika y’obutoffaali buno obwa kookolo efuuka ya njawulo nnyo era etali ya bulijjo ku butoffaali obulamu. Enjawulo eyo, obutali bwa bulijjo obwo, abakugu mu by’endwadde kye bawa ekipimo.

Enkola y’okugaba obubonero

Buli sampuli y’ebitundu by’omubiri bawa obubonero okuva ku 1 okutuuka ku 5 okusinziira ku butonde bw’obutoffaali bwa kookolo, kwe kugamba, bwe bwawukana ku butoffaali obulamu. Kino kiyitibwa ekigero kya kookolo .

• Ekibiina 1: Obutoffaali bwa kookolo bufaanana nnyo obutoffaali obulamu, obwa bulijjo. Kwe kugamba, waliwo enjawulo ntono nnyo. Zitegekeddwa mu ngeri entegeke.
• Ebibiina 2-4:Obutoffaali bwa kookolo mu bitundu by’omubiri bulabika nga bwa njawulo katono ku butoffaali obulamu era bulabika nga tebuteredde. Ekigezo bwe kyeyongera, enjawulo eno n’obutabeera bulungi byeyongera okweyoleka.
• Ekibiina eky’okutaano: Obutoffaali bwa kookolo tebuli bwa bulijjo nnyo, bulabika nga tebutegekeddwa bulungi era nga tebukwatagana na butoffaali bulamu. Buno bwe butoffaali obusinga okubeera obulumbaganyi.

Kati, kookolo w’enseke asobola okuba n’obutoffaali bwe bumu mu kitundu kimu, oba asobola okuba n’obutoffaali obw’eddaala ery’enjawulo mu bitundu eby’enjawulo. Kale, omusawo w’endwadde ky’akola kwe kulonda ekitundu ekikulu kookolo w’asinga okusaasaana n’amuwa ekigezo (wakati wa 1-5). Olwo, balondawo ekitundu ekyokubiri ekisinga okusaasaana (ekirina omusono ogw’enjawulo) ne bakiwa ekigezo. Olwo ebigezo ebikulu ebibiri ne bigattibwa wamu. Omugatte ogwo gwe Gleason Score yo.

Okugeza, katugambe nti kookolo asinga obungi ye grade 3. Eddako okusinga obungi ye grade 4. Olwo obubonero bwa Gleason bwandibadde 3 + 4 = 7. Ekyokulabirako ekirala, singa pattern efuga eba grade 4 ate secondary pattern eba grade 3, Gleason score yandibadde 4 + 3 = 7. Kale newankubadde 3+4 ne 4+3 byombi 7, abasawo oluusi balowooza ku ensengeka y’enkola zino (ekibiina eky’oku ntikko ekisooka).

Okutwalira awamu, singa obubonero buno obwa Gleason obugatta buba 6 oba okusingawo, butwalibwa nga kookolo.

Waliwo ekintu ekiyitibwa Gleason Score eya bulijjo?

Kati oyinza okuba nga weebuuza, waliwo "normal" Gleason Score? Mu butuufu, tewali kintu kiyitibwa "bulijjo" Gleason Score, nga bwe tukebera emiwendo gya ssukaali mu musaayi gwaffe oba ssukaali, oba bwe tutunuulira emiwendo gyaffe egya kookolo w'enseke PSA ne tugamba nti, "Wano ye range eya bulijjo." Wabula abasawo bagabanyaamu Gleason Score mu biti bisatu ne babikozesa okutegeera enneeyisa ya kookolo:

• Gleason score 6: Mu mbeera eno, obutoffaali bwa kookolo bulabika nga bufaanagana nnyo n’obutoffaali obulamu. Kino tukiyita kookolo wa ``well differentiated'' . Mu ngeri ennyangu, obutoffaali bukyali nga "abaana abalungi," nga bugezaako okufaanana obutoffaali obwa bulijjo. Zino zitera okutwalibwa nga kookolo akula mpola, atali mukambwe nnyo.
• Gleason score 7: Mu mbeera eno, obutoffaali bwa kookolo bufaanana katono obutoffaali obulamu, naye waliwo obutali bwenkanya. Kino tukiyita kookolo wa ``moderately differentiated'' . Kino kiringa ekifo ekiri wakati. Wayinza okubaawo enjawulo entono wakati wa 3+4=7 ne 4+3=7. Enkola ya 4+3 oluusi etwalibwa ng’embeera eyeraliikiriza katono okusinga enkola ya 3+4.
• Gleason obubonero 8, 9 oba 10:Mu mbeera eno, obutoffaali bwa kookolo bwa njawulo nnyo ku butoffaali obulamu. Zitabeera za bulijjo nnyo, kumpi tezaawulwamu. Kino tukiyita kookolo ‘atayawulwa bulungi’ oba ‘atayawulwamu’ . Obutoffaali buno buba bukambwe katono, era bulabika nga bulina emikisa mingi okukula n’okusaasaana amangu.

Gleason Score ennungi ku kookolo w’enseke kye ki?

Kizibu okuwandiika amangu ddala obubonero bwa Gleason nti "obulungi" oba "bubi." Wabula okumanya obubonero bwo obwa Gleason kiyinza okuwa omusawo wo endowooza enkulu ku ngeri kookolo wo ey’enseke gy’akula amangu n’engeri gy’ayinza okusaasaana mu bitundu by’omubiri ebirala. Obukodyo bwa Gleason buva ku 6 okutuuka ku 10.

Okutwalira awamu, singa obubonero bwa Gleason buba butono (okugeza, 6), butwalibwa nga ‘kookolo ow’omutindo ogwa wansi.’ Ebika bya kookolo bino bikula mpola era tebitera kusaasaana mu bitundu birala.

Singa obubonero bwa Gleason buba bungi (okugeza, 8, 9, 10), butwalibwa nga ‘kookolo ow’omutindo ogwa waggulu.’ Ebika bya kookolo bino bitera okukula n’okusaasaana amangu.

Naye, kikulu okujjukira kino: Obukodyo bwo obwa Gleason kitundu kimu kyokka abasawo kye bakozesa okuteekateeka obujjanjabi bwo n’okukuwa okuteebereza. Ekyo kitegeeza nti ggoolo ya Gleason yokka si y’eky’okuddamu. Kiba kitundu kimu kyokka ku kifaananyi ekinene.

Gleason Score ye yokka esinga obukulu?

Nedda, si bwe kiri n’akatono. Nga bwe nnagambye emabegako, Gleason Score yo kitundu kimu kyokka ku puzzle. Abasawo balowooza ku bintu ebirala bingi okusobola okutegeera embeera yo mu bujjuvu ne balondawo obujjanjabi obusinga obulungi.

Ng’ekyokulabirako, bwe wali okukeberebwa omubiri gwo, omusawo wo ayinza okuba nga yaggyayo sampuli eziwerako, eziyitibwa cores, okuva mu prostate yo. Ekituufu,

• Ku bitundu ebyo ebikulu (ebitundu by’ebitundu by’omubiri) bimeka ebyalimu obutoffaali bwa kookolo?
• Ebitundu ki ku buli kikumi ebya buli `(core)` ebyajjula obutoffaali bwa kookolo?

Nze era ntunuulidde ebintu ng'ebyo.

Okugatta ku ekyo, ebintu bino nabyo bikulu nnyo:

• Omusaayi gwo ogwa `(PSA)` level. (PSA - Prostate-Specific Antigen) (okukebera omusaayi mu ngeri ey’enjawulo).
• Ebyava mu kukeberebwa kw’omumwa gwa nnabaana okwa digito (DRE) okukolebwa omusawo (kwe kugamba, engeri endwadde gy’ewulirwamu mu ngalo).
• Amawulire agava mu kukebera ebifaananyi okw’enjawulo nga ultrasound scans, MRI scans, oba PET scans gasobola okuyamba okuzuula obunene n’okusaasaana kwa kookolo.
• Oba kookolo ali ku njuyi zombi ez’enseke.
• Kigambibwa nti kookolo w’enseke yasaasaana (metastasized) mu bitundu by’omubiri ebirala okugeza amagumba.
• Emyaka gyo n’obulamu bwo okutwaliza awamu.

Bino byonna okubiteeka wamu, ng’okumaliriza puzzle ennene, y’engeri omusawo gy’agenda okusalawo obujjanjabi obusinga obulungi gy’oli, okusinziira ku mbeera gy’olimu. Kale, tofaayo mu ngeri eteetaagisa ku bubonero bwa Gleason, okay?

Ekintu ekisinga obukulu ky’olina okukuuma mu birowoozo (Take-Home Message)

Okay, kale wuuno ekintu ekisinga obukulu okujjukira okusinziira ku bye twogeddeko. Gleason Score kye kimu ku bikozesebwa ebikulu ebigabanya kookolo w’enseke n’okukuwa ekirowoozo ku ngeri gy’akola obusungu. Omusawo akikozesa okuteekateeka obujjanjabi obusinga obulungi gy’oli. Gleason Score esobola okuva ku 6 (kookolo ow’omutindo ogwa wansi, atali mukambwe nnyo) okutuuka ku 10 (kookolo ow’omutindo ogwa waggulu, asinga okubeera omukambwe). Kookolo alina Gleason Score entono atera okukula mpola era nga talina bulabe butono obw’okusaasaana.

Naye ennamba zino zokka tezinyumya nsonga yonna ku kookolo wo ow’enseke. Emboozi eyo etandikira ku nteekateeka yo ey’obujjanjabi n’okutegeera ky’oyinza okusuubira mu bujjanjabi obwo, awamu n’ebirungi n’ebibi. Obukodyo bwo obwa Gleason n’ebyava mu bigezo ebirala biringa ekikulaga okukuyamba mu lugendo lwo olw’okudda engulu.

Bw’oba ​​olina ekibuuzo kyonna oba ekikweraliikiriza ku Gleason Score yo, ebyava mu kukeberebwa okulala kwonna, oba embeera yo ey’obujjanjabi, tolwawo kubuuza musawo wo. Ajja kusanyuka okunnyonnyola ennamba n’ebigambo ebyo kye bitegeeza n’okuddamu ebibuuzo byonna by’oyinza okuba nabyo. Jjukira nti toli wekka mu lugendo luno. Waliwo abasawo ne ttiimu y’ebyobulamu okukuyamba n’okukulabirira.

` Kookolo w’enseke, obubonero bwa Gleason, obutoffaali bwa kookolo, okukebera ebitundu by’omubiri, okuteekawo kookolo mu mitendera, obulamu bw’abasajja, obujjanjabi bwa kookolo