Kan nerve cells vel hualtu myelin sheath hi eng nge ni? Chipchiar takin sawi ila!

Kan taksa chhunga palai te te, nerve cell te hian engtiang chiahin nge hna an thawh chak a, engtiang chiahin nge an fing tih i ngaihtuah ngai em? Dik tak chuan kan taksa pum pui, kan ngaihtuahna atanga kan kut leh ke kan chet dan thlengin he nervous system hian a thunun a ni. Chuvangin vawiin hian heng nerve cell te hnathawh thatna tura puitu thil pawimawh tak kan sawi dawn a ni. Chu chu Myelin Sheath a ni .

Myelin Sheath hi eng nge ni? A awlsam zawngin i hrethiam ang u!

A awlsam zawngin sawi ila, myelin sheath hi kan nerve cell (`(Neuron)` kan ti bawk) tinte hualtu venna khuhna a ni. Glove tlemte ang mai a ni. Thau (i.e. `(Lipids)`) leh protein atanga siam a ni. He khuhna hian nerve cell "trunk" part lian ber a khuh a, chu chu axon an ti a ni. Kan in chhunga electric wire ang maiin han ngaihtuah teh. Copper wire vel chu plastic sheath a nei a. Chutiang chuan he myelin sheath hian nerve cell te chu a venghim a, an hnathawh dan tur a pui bawk.

Neuron chhunga thil awmte chu engte nge ni? Thingkung ang mai a ni!

Myelin sheath chungchang kan sawi belh hmain nerve cell chu eng nge a nih leh a peng hrang hrangte chu eng nge ni tih i hrethiam ang u. Nerve cells hian kan nervous system a siam a . He nervous system hi kan taksaa information exchange center lian ber ang a ni. Taksa hmun hrang hrang a\angin thu a dawng a, a chhang let a, taksa chhung leh pawna thil thlengte nen a insiamrem \hin. Nerve cell kan ngaihtuah hian a peng lian pathum a nei a. Nerve cell chu thing ang maiin han ngaihtuah teh : 1. Soma emaw Cell Body: Hei hi thing zung ang a ni. Dendrites , soma zung ang maia awm te hian lei atang hian "nutrients" an la lut thin. Mahse hetah hian "nutrients" tih hi a bul hnaia nerve cell dang atanga chemical message lo lut a ni. Chumi hnuah chuan heng thuchahte hi electrical impulse-ah an chantir leh thin. He soma chhungah hian cell nucleus pawh a awm bawk. 2. Axon: Hei hi thing hnah sei tak ang a ni. Thingkung zung atanga ei tur tha lo (nutrients) te chu a hnah atanga a kal chhoh ang bawkin, axon hian soma atanga electrical impulse lo chhuak te chu a kal tlangin a phur bawk a ni. 3. Axon Terminal: Hei hi thing hnah tawp lama hnah awm ang a ni. Heng buds atang hian hnah leh pollen a chhuak thin. Chutiang chuan he axon terminal atang hian electrical impulse te chu "released" a ni a, chutiang chuan nerve cell lo awm tur chuan a la thei ta a ni. Hetiang hian thuchah chu i thluak, i ruhro , a nih loh leh i taksa peng dang a thlen thlengin a kal zel a ni. Chumi rah chhuah chu i kut tichak turin, thawk chhuahna tura puitu emaw, i thinlung ti na thei tur emawa taksa peng hrang hrangte inzawmkhawm ang chi thil a ni. Tunah chuan nerve cell awm dan bulpui chungchangah hian ngaihtuahna tlem i nei mai thei.

Myelin Sheath hi engtin nge a awm?

Myelin sheath hian hna pawimawh pathum a nei a, chungte chu:

• Invenna pe: Ka sawi tawh ang khan he lipid-protein coating hian nerve cell tan venhimna insulation a pe a, electrical cable wire vel plastic sheath ang bawkin.
• Inbiakpawhna chak tak: Hei vang hian electrical impulse te chu nerve cell pakhat atanga a dang thlengin rang tak leh tha takin an kal thin . Myelin tel lo chuan he zinkawng hi a slow hle ang.
• Impulse chakna vawn reng: He myelin sheath hian thuchah chu axon-a a kal laiin a chakna vawng reng turin a pui a ni.

Myelin hi kan thluak leh ruhro (spinal cord)-a oligodendrocytes an tih cell ( Central Nervous System (CNS) kan tih) atanga siam a ni a, chutiang bawkin myelin hi kan Peripheral Nervous System (central nervous system pawn lama nerve network, taksa pum puia darh) a Schwann cell te siam a ni taksa dang zawng zawng.

Myelin sheath chhunga gap awmte chu eng nge an tih?

Myelin sheath hi continuous, thick covering angin ngaihtuah suh. Ni lo, box rel sei tak ang mai a ni. Box pakhat tawp a, box dang a intanna hmunah chuan gap tlemte a awm. Chutiang bawkin myelin sheath pawh hi myelin strand hrang hrang atanga siam a ni a, chu chu a inthen a ni. Heng myelin strand tin hi internode an ti a . Heng myelin strand pahnih inkar gap te te hi node of Ranvier an ti a . Ranvier-a heng node-ah hian positive sodium ion tam tak a awm a. Electrical signal, a nih loh leh impulse chu axon-a a kal chuan Ranvier-a node pakhat aṭangin a dangah a zuang thla a ni. He gap hi a pelh chuan sodium ion te hian electrical signal chu an recharge leh thin. Tichuan signal chu a charge hloh lovin emaw, a chakna hloh lovin a kal chhunzawm thei a ni. Mechanism mak tak a ni a ni lawm ni?

Myelin sheath a chhiat chuan eng nge thleng ang?

Kan taksaah hian nerve cell tluklehdingawn 100 vel a awm niin an sawi. Chung zawng zawng chu kan thawkrim reng a, thuchah thawn leh dawngtu, kan taksaa hnathawh zawng zawng thunun vek a ni. Heng nerve cell chhehvela myelin sheath hi a chhiat chuan eng nge thleng ang tih han ngaihtuah teh. Tichuan electrical signal speed chu a tlahniam ang a, a nih loh leh a tawp vek thei bawk. Myelin chhiat chhan ber pakhat chu kan taksaa immune system a ni.Cell te hian myelin hi pawn lam atanga thil danglam tak niin an ngai sual a ni. Tichuan kan immune system chuan myelin chu a rawn bei tan ta a ni. Hei hian inflammatory substance a siam a, chu chuan myelin a tichhia a ni. A tawpah chuan myelin siamtu cell (oligodendrocytes leh Schwann cells) te pawh an thi ve bawk. Hetianga myelin sheath tihchhiatna hi demyelination an ti a . Myelin a beih na hmun a zirin i natna lan chhuah dan a inang lo ang.

Eng natna nge myelin tichhe?

Myelin tichhe thei natna engemaw zat a awm a. Heng natna thenkhat hi i hre tawh mai thei.

Central nervous system (CNS)-a myelin natna vei:

Mi tam zawkin an hriat tawh, central nervous system (chu chu thluak leh ruhro) myelin beitu natna tlanglawn ber chu multiple sclerosis a ni. Chu bakah, central nervous system-a myelin tichhe thei natna dang engemaw zat a awm bawk:

• Acute Disseminated Encephalomyelitis: Hei hi immune reaction awm lo, acute, na tak, central nervous system-a awm a ni.
• Schilder's Sclerosis: ``Diffuse Myelinoclastic Sclerosis'' tia hriat bawk a ni a, hei hi naupangte zingah neurodegenerative natna hmuh tur awm lo tak a ni.
• Transverse Myelitis: Hei hi autoimmune natna a ni a, ruhro (spinal cord) a ti na a ni.
• Neuromyelitis Optica: Hetah hian immune system chuan mit leh ruhro nerve te chu antibodies hmangin a bei thin .
• Optic Neuritis : Hei hian mit nerve inflammation a keng tel bawk.
• Tumefactive Demyelination : Hei hi myelin tichhe thei lesion pakhat, centimetre 2 aia lian a ni.

Peripheral nervous system-a myelin natna vei te:

• Guillain-Barre Syndrome: Heng natna lan chhuah dan hi natna kai hnuah emaw, a tlem hle a, vaccine pek hnuah emaw a awm thei.
• Chronic Inflammatory Demyelinating Polyradiculoneuropathy ( CIDP ): Hei hi autoimmune natna zual zel a ni a, myelin a bei thin.
• Paraproteinemic Demyelinating Neuropathy: Hei hi cancer nena inzawm antibody awmna nena inzawm neuropathy chi khat a ni.
• Charcot Marie Ha natna type 1 leh type X: Hei hi inherited neurological disease a ni.
• Copper tlakchhamna: Copper level a hniam chuan myelin hian a venhimna a hloh a, a chhe awlsam zawk.

Eng dinhmun dang nge myelin tichhe thei?

Puitlingah chuan myelin sheath a chhe thei emaw, a chhe thei emaw chhan dang a awm bawk:

• Stroke a awm
• Infection, Immune leh Metabolic Disorders (`(Metabolic Disorders)`) te hi a tha lo hle.
• Poison chi hrang hrang
• Vitamin B12 tlakchhamna
• Damdawi thenkhat, entirnan `(Ethambutol)`
• Zu in tam lutuk

Chu bâkah, thlahtute natna chi hrang hrang, hmuh tur awm lo tak takah chuan myelin sheath chu a insiam ṭha lo hle bawk. Entirnan , Tay-Sachs Disease , Gaucher Disease , Hurler Syndrome, leh Niemann-Pick Disease te hi a ni.

Kan taksaa thuchah kengtu heng kawng chak tak takte hi, lirthei tlan laia kan tang ang maia khap a nih chuan kan taksa hnathawh a tihchhiat nasat zia hi han ngaihtuah teh. Chuvangin myelin sheath hriselna hi a pawimawh em em a ni.

Myelin chhiatna chu siamthat theih a ni em?

Hei hi mi tam takin zawhna an neih chu a ni. Ni e, myelin chhia chu siamthat theih a ni , central nervous system-ah leh peripheral nervous system-ah te. Mahse myelin tihchhiatna thlentu thil, inflammation ang chi te control a pawimawh a, immune suppression/modulation (entir nan , steroids , intravenous immune globulin (IVIG) , leh damdawi dang) hman a pawimawh bawk. Scientist-te chuan myelin siamthatna tihhmasawn theih dan tur hriatthiamna kawngah hmasawnna nasa tak an nei a ni. Zirna beisei awm tak tak awm mahse, damlote tan engzat nge hlawkna an neih tak tak tih erawh a la chiang lo. Tunah hian myelin siamthatna tur damdawi pawmpui a la awm lo. Zirna a\anga entirnan tlemte chauh chu hetiang hi a ni:

• Phase II clinical trial tenau takah chuan oral antihistamine clemastine hian myelin siamthat theihna a nei tih hmuhchhuah a ni. Clemastine hian multiple sclerosis vei, optic nerve chhiatna nei te electrical signals transmission a ti tha hle. Mihring trial hmasa dang pakhatah chuan zunthlum damdawi metformin leh clemastine te inkawp hian myelin siam thar lehna a pui tih hmuhchhuah a ni.
• Stem Cells te hi a awm aCentral nervous system-a myelin siamtu oligodendrocyte cell-a molecule pakhat block-in (hengte hi cell chi hrang hrang "building block" an ni) a, multiple sclerosis ang chi symptom nei mice-te chuan an myelin chu an siam ṭha thei a, eng emaw chen chu an dam leh thei a ni.
• Stem cells hian myelin chhiatna a siam that theih dan leh natna a zual zel dan tur a tikhawtlai thei tih zirchianna neih chhunzawm zel a ni.
• Damdawi dangte chuan nervous system chhiatna nasa zawk laka humhimna kawngah thutiam an nei tih an lantir. Anti-inflammatory drug ibudilast hian Phase II trial-ah thluak cell thihna (atrophy) rate nasa takin a tihhniam a ni. Epilepsy damdawi phenytoin hi a him tih hmuhchhuah a ni a, placebo nena khaikhin chuan myelin chhiatna chu 30% in a tihtlem phah a ni. Antioxidant lipoic acid hian nerve fibers tihchhiat belh zel tur a veng thei a ni.

Take-Home Thuchah a ni

Chuvangin, tunah hian he myelin sheath hi kan nervous system hrisel taka hnathawhna atana a pawimawh zia chu i hmu thei tawh ang. Kan taksa peng tin nena inbiakpawhna leh engkim thunun thei heng nerve cell maktaduai tam takte hnathawh dan tur dik tak atan hian myelin hi a pawimawh hle.

• Myelin hi nerve cells vel hualtu thau leh protein atanga siam, venhimna (protective sheath) a ni.
• Nerve impulse te chu rang tak leh tha taka kal turin a pui thin.
• Myelin chhiatna hian natna khirh tak tak, multiple sclerosis ang chi a thlen thei a ni.
• Myelin chhiatna thlentu natna enkawl leh siamthat dan tur zirchianna kalpui mek a ni.

Natna leh dinhmun tam takin myelin hi a bei thei a ni. Heng zingah hian multiple sclerosis hi hriat lar ber a ni. Mahse thu lawmawm tak chu zirchiangtute chuan myelin venhimna, siam that leh siam thar dan tur an zawng reng a ni. Tin, chutianga an tih kawngah hmasawnna engemaw zat an nei mek bawk. Chuvangin, beiseina a awm!

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Myelin, myelin sheath, nerve cells, neurons, nervous system, central nervous system, peripheral nervous system, demyelination, multiple sclerosis te hi a awm thei lo