I ke leh i hmai te hi zawi zawiin a pianzia a inthlak a, a lian chho zel em? Acromegaly chungchang hi han sawi ila.

I pheikhawk size a lian chho zel emaw, i ring hlui kha tunah chuan i kut zungtang-ah a innghat tawh ang tih i hre ngai em? Thlalak hlui i en hian i hmai pianzia hi a danglam deuh mai thei em? Heng thil tam tak hi hun kal zelah a thleng thin a, a chang chuan kum tam tak chhung a thleng thin a, chuvang chuan kan ngaihven vak lo. Mahse hei hi Acromegaly tih hming pu natna hlauhawm tak chhinchhiahna a ni thei. Ngaihtuah buai suh, thumal awlsam takin engkim kan sawi dawn a ni.

A awlsam zawngin, Acromegaly chu eng nge ni?

Acromegaly hi kan taksain growth hormone, a nih loh leh Growth Hormone (GH) a siam tam lutuk vang a ni. He hormone hian kan naupan laiin min pui thin. Amaherawhchu, he hormone hi kan lo seilian zawh hnu, chu chu puitling kan nih hnuah pawh a chhuak chhunzawm zel a nih chuan, kan taksa peng thenkhat, a bik takin kut, ke leh hmai ruh te chu a pangngai lo takin a lian tan thin.

Hetiang dinhmun hi kum chanve velah hmuh tur a awm tam ber. Mahse hei hian naupang zawkah a thleng lo tihna erawh a ni lo. Kum naupang takah hetiang hian growth hormone a pung a nih chuan chu natna chu gigantism an ti a ni. Tichuan, danglam takin an sang chho ta a ni.

Engvangin nge acromegaly hi a lo awm? A chhante chu engte nge ni?

Hei hi a chhan ber chu kan thluak bul hnaia pea ang maia lian gland te tak te a awm vang a ni. Pituitary Gland kan ti a . Acromegaly thlentu ber chu he gland-a noncancerous (benign) tumor a ni. He tumor hi Pituitary Adenoma an ti a . He tumor hian pituitary gland a tichak a, growth hormone (GH) a siam tam lutuk bawk.

He GH hormone tam lutuk hi kan thisenah a pung khawm a, liver chu hormone dang IGF-1 (Insulin-like Growth Factor-1) tih siam turin signal a pe a ni. Chu IGF-1 hormone chu kan ruh leh taksa peng dangte tipungtu chu a ni. Kan taksain sugar leh thau a control dan a nghawng bawk a, natna dang vei theihna a tipung a ni.

A tlem hle a, he natna hi pancreas, liver emaw thluak hmun danga tumor lo awm vang pawh a ni thei. Research atanga a lan dan chuan genetic factor thenkhat pawhin hmun a chang thei bawk.

Acromegaly natna lan chhuah dan chu engte nge ni?

Heng symptoms te hi zawi zawiin a lang fo thin a, chuvangin a danglamna i hriat theih nan hun rei tak a la ngai thei.

He natna hi engtin nge kan hriat theih ang?

Hetiang dinhmun hi a rang thei ang bera hriat a pawimawh. Heng symptoms te avang hian doctor i hmuh chuan hetiang hian zawhna a zawt ang che:

• Eng inthlak danglamna nge i hmuh?
• Engtikah nge heng inthlâk danglamnate hi i hriat hmasak ber?
• Tunah hian engtin nge i awm?

Tichuan, test eng emaw zat an nei a, chu chu a natna hmuhchhuah a nih thu finfiah a ni.

Test lian ber ber te

• Thisen test: Thisen test hi IGF-1 hormone level chu i kum a zirin a sang em tih enfiah thin a ni.
• Glucose Tolerance Test: Hetah hian sugary drink an pe che a, darkar hnih chhung i thisen sugar leh GH hormone level an teh thin. A tlangpuiin sugar in hnuah GH level a tlahniam tur a ni. An tih loh chuan, leh sang taka an awm reng chuan acromegaly chhinchhiahna a ni.

Test dang pawh a awm

• MRI emaw CT scan: Heng scan te hian pituitary tumor hriatchhuah nan a pui thin.
• X-ray test: Ruh a thim em tih enfiah thin ang che.
• Echocardiogram: Thinlung hi a nghawng tawh em tih hriat nan ultrasound test a ni.
• Colonoscopy: Colon hriselna enfiah thin.
• Sleep Study: Sleep Apnea i nei em tih en rawh.

Enkawlnate chu engte nge ni?

I doctor chuan i kum, i hriselna dinhmun leh i natna nasat dan a zirin i tana enkawlna tur ruahmanna dik ber a ruat ang. Enkawl dan chi thum a awm a.

1. Surgery neih dan tur:

Vawi tam tak chu enkawlna hmasa ber chu pituitary tumor lakchhuahna operation a ni. Hei hi a pawimawh hle a, tumor hian mit hmuhna tichhe thei nerve a press a nih chuan. Surgeon chuan hnar emaw, hmui chunglam chhungah emaw incision te tak te hmangin tumor chu a paih chhuak thin. Operation hnu ni engemaw zat chhungin symptoms a lo tha chho tan thei bawk.

2. Damdawi: 1.1.

Operation hnua tumor piece la awm emaw, i hormone level control-na atana tanpuina tam zawk i mamawh emaw chuan i doctor chuan damdawi a pe ang che. Heng damdawi te hian i GH level a tihhniam emaw, taksa a a nghawng dan a block emaw a ni.

• Somatostatin analog (e.g. lanreotide, octreotide) te hi a inang lo hle.
• Growth hormone receptor dotu (e.g. pegvisomant) te hi a tha hle a ni.
• Dopamine agonists (e.g. cabergoline) te hi a tha hle.

3. Radiation Therapy hmanga enkawlna: 1.1 .

Operation leh damdawi ei hnuah pawh tumor hmun thenkhat a la awm a nih chuan, emaw GH level tihhniam belh a ngai a nih chuan radiation therapy hman thin a ni. Hei hian tumor a tipung thei lo va, GH siamchhuah a ti tlem bawk. Tunlai technique te, stereotactic radiosurgery te hian tissue hrisel tichhe lovin tumor ah hian radiation dose sang tak a pe thei a ni.

Enkawl loh chuan harsatna awm thei

Acromegaly hi a enkawl that loh chuan hriselna lama harsatna lian tak a thlen thei a, chuvangin he natna hi ngaihthah suh.

• Lung leh thisen zam natna
• Zunthlum
• Thisen sang a sang
• Arthritis (Ruh natna) .
• Carpal Tunnel Syndrome natna a ni
• Mut Apnea (Sleep Apnea) a awm
• Mit hmuhna hloh
• Colon cancer vei theihna a sang
• Spinal nerve tihchhiat a ni