I cell hmanga cancer damdawi? Autologous Stem Cell Transplant chungchang hi han sawi ila

Cancer do mek mi pakhatin doctor-in, "Stem cell transplant kan ti dawn" a tih hian a hlauthawng deuh hi thil pangngai a ni. Mahse "autologous" tih thumal an sawi chuan he enkawlna hi nangmah ngeiin i cell hmanga tih a ni tihna a ni. Hei hi i taksain cancer dona chakna pe theitu tha tak a ni tak zet a ni. Okay, chuvangin hei hi eng ang taka buaithlak nge a nih, eng nge a tih tak tak, leh he process hi a hnathawh dan hi a awlsam em em a, step by step-in i sawi dawn nia.

A awlsam zawngin, autologous stem cell transplant tih hi eng nge ni?

Hei hi han mitthla teh. I computer chu virus vangin a buai zo vek tawh. Tunah chuan he virus hi paih chhuah tur chuan computer hi a `format` vek a ngai tawh a ni. Mahse, chumi hma chuan eng nge i tih? I file pawimawh ber berte chu hmun hranah i `back up` em?

Autologous stem cell transplant pawh chutiang bawk chu a ni.

Heta thil thleng chu, cancer cells tihhlum nan chemotherapy sang tak emaw, radiation therapy emaw i dawn hmain, nangmah ngeiin i thisen stem cell hrisel thenkhat chu i taksa atangin lakchhuah a ni a, him takin a sir lamah dah a ni. Heng stem cells te hi kan ruhro chhunga "mother cells" te an ni a, thisen sen thar, thisen var, leh platelet te an siam thin.

Cancer dona damdawi chak tak takte hian cancer cell te a tihlum hian kan cell hrisel te pawh a tichhe bawk a, a bik takin ruhro (bone marrow) te pawh a tichhe bawk. Tichuan, nangmah ngeiin stem cell hrisel tak tak, him taka vawn tawhte chu i taksaah a rawn lut leh ta a ni. Heng cell te hi ruhroah an kir leh a, taksa mamawh thisen cell hrisel tak tak an siam tan ta a ni.

He enkawlna hi cancer natna `Multiple Myeloma` tan hman a ni tlangpui. Cancer natna chi hrang hrang `Hodgkin lymphoma` leh `Non-Hodgkin lymphoma` te tan pawh hman a ni a, enkawlna dang a chhang lo.

He enkawlna hma hian eng nge thleng thin?

Chutiang enkawlna chak tak i neih hmain doctor-te chuan i hriselna zawng zawng chu uluk takin an enfiah ṭhin a, i taksa chu chemotherapy dose sang tak tuar thei tur khawpa chak a ngai a ni.

Test tih theih thenkhat:

• `ECG` (Electrocardiogram) test, thinlung thawk dan enfiahna a ni.
• Thinlung hnathawh dan enfiahna `Echocardiogram` a ni.
• `CT` (Computed Tomography) hmanga tih a ni.
• Thisen chhiar kim (CBC) a ni.
• Thisen test dang, liver leh kidney hnathawh dan enfiahna.
• Biopsy hi cancer cell zir chianna atana test a ni.

Tunlai hian needle i lak chhunzawm zel ngai loh nan doctor-te chuan i rilru chunglam vein lian takah tube te tak te `Central Venous Catheter (CVC)` an dah thei a. Tichuan, thisen lak atanga damdawi pek thlengin he `CVC` hmang hian awlsam takin tih theih a ni.

Enkawlna atana hmalakna lian pathumte

Hetiang kalphung zawng zawng hi stage lian pathum ah then theih a ni.

1. Stem cells lakkhawm

Hei hi kan sawi tak stem cell hrisel tak takte kha i taksa atanga lakchhuahna hmun a ni. Hei hi `Apheresis` an ti bawk.

• I kut pahniha vein te chu cell separation machine nen a inzawm ang.
• Kut pakhat atang chuan thisen tlem chu machine chhungah a lut a.
• Machine hian chu thisen atanga stem cells chauh a filter a, thisen la awm chu a kut dang hmangin taksaah a inject leh thin.

Hei hian darkar thum atanga darkar li vel a daih thei. Chumi chhûng chuan i awm reng a ngai mai thei a, mahse lehkhabu i chhiar thei a, TV i en thei bawk.

2. Taksa conditioning

Hei hi a harsa ber a ni. Hei hi cancer cells tihhlum nan chemotherapy dose sang tak leh radiation therapy pawh i dawng thei dawn a ni. Hei hian ni engemaw zat a daih thei. Hemi hun chhunga side effect awm thei zawng zawng enkawl turin i medical team te chu i bulah an awm ang.

3. Cell thlak / Infusion

Hei hi saline solution emaw thisen pack emaw pek nen a inang a ni. I stem cells, him taka khawlkhawm leh dahkhawmte chu IV emaw CVC emaw hmangin i taksaah dah leh a ni. Hemi chhung hian medical team chuan khawsik leh khawsik ang chi symptoms i neih leh neih loh an enfiah reng ang che.

Enkawl hnuah eng nge thleng? Recovery period chungchang i zir chiang ang u

Enkawl zawhah i taksa chu zawi zawiin a lo dam tan ang.

• Engraftment: Stem cells infuse tharte hian thisenah an kal a, ruhroah an awm a, thisen cell hrisel thar an siam tan thin. Hetiang kalphung hi `Engraftment` an ti a.
• Infection Risk: Engraftment hnuah i thisen var cell count a normal leh hma loh chuan i infection risk a sang hle. Chuvangin he hun chhung hian natna hrik laka inven a pawimawh hle.
• Recovery time: I immune system a dam kim theih nan thla 3 atanga thla 12 vel a ngai thei. Chuvangin hmanhmawh suh. I tanpui thei tur thil thenkhat chu hetiang hi a ni:
• Chawlh tam rawh: Ni engemaw zat chu i chau hle mai thei. Chutih hunah chuan chawlh hahdam rawh.
• Chaw tha ei: Protein tamna ei hian taksa siam that lehna a pui thin.
• Exercise: I chakna i hriat veleh kea kal ang chi exercise awlsam tak tak ti tan la. Mahse thil thar i tan hmain i doctor nen inbiakna neih hmasak phawt ang che.
• I vaccine pek dan kha update rawh: Hetianga enkawlna i neih zawh hian naupan laia vaccine lak atanga i venhimna i dawn kha a bo vek ang. Chuvangin i doctor chuan engtikah nge vaccine lak leh tur tih leh eng vaccine nge i lak tur tih a hrilh ang che.

Autologous leh Allogeneic transplant te hi eng nge an danglamna?

An pahnih inthlauhna ber chu cell awmna hmun a ni. Hei hi awlsam taka hriatthiam theih nan a hnuaia table hi en la.

Doctor hmuh nghal hun tur

Enkawlna i neih hnua medical checkup neih fo pawh nise, harsatna i neih chuan i medical team hriattir nghal a pawimawh. A hnuaia symptoms te hi en reng ang che:

• Khawsik
• Khua a vawt a, a khur bawk
• Thâwk harsa (Dyspnea) .
• Khuh, thawk hah, hnar luang chhuak
• Zun tam emaw, zun laiin natna emaw (Dysuria) .
• Vun a hring chhuak
• Luak chhuak thei