I rilru a hahdam a, nunna nei loin i inhria em? Cachexia (Wasting Syndrome) chungchang hi i zir dawn teh ang!

A chang chuan, ‘Aw, engvangin nge ka cher em em? Ei pawh ka ei thei lo. Nilengin ka chau lutuk.' A nih loh leh, i hnaih bertu mi pakhatin he natna hi a vei i hmu tawh em? Dik tak chuan, natna khirh tak tak, hun rei tak chhunga awm thei thenkhat nen pawha lo awm thei dinhmun tibuaitu tak a awm a ni. Doctor te chuan Cachexia , a nih loh leh Wasting Syndrome an ti a . Hei hi a takah chuan khawvel puma mi maktaduai 9 velin a nghawng thei dinhmun a ni. A awlsam zawngin taksa chu zawi zawiin a tichhe vek a ni. He hming hi Greek tawng pahnih, "kakos" (tha lo) leh "hexis" (condition) atanga lo chhuak a ni. Chuvangin, "bad body condition" tih hi a awmzia a ni. Hei hi thil awlsam a ni lo, mahse chipchiar takin sawi ila, a chhan chu hriat chian a pawimawh em em a ni.

Cachexia natna lan chhuah dan chu engte nge ni?

Doctor-te chuan he natna chungchang hi an sawi hian "cachectic" tih thumal hi an hmang mai thei. Nangmah emaw i hriat emaw hian heng symptoms te hi a nei em tih en rawh:

• Sawifiah loha taksa rihna tlahniam: Hei hi a lan chhuah dan ber a ni. I taksa rihna tihtlem tum lo leh ei leh in hrisel i ei lai pawhin i thau chhunzawm zel a ni. A tlangpuiin thla 6 atanga thla 12 chhunga i taksa rihna zawng zawng atanga 5% aia tam i tihtlem chuan doctor te chuan an ringhlel mai thei. Entirnan, kilo 60 i rit chuan kilo 3 emaw a aia tam i tihtlem chuan hei hi a chhinchhiahna a ni thei.
• Muscle loss: Doctor-te chuan hei hi muscle wasting emaw muscle atrophy emaw an ti bawk. A awlsam zawngin, i taksa ruhte hian an chakna an hloh zauh zauh a. An te deuh a, an chak lo deuh bawk. A hmaa hna awlsam tak takte pawh chu tih harsa angin i hmu mai thei.
• Chauhna leh chak lohna: Hei hi hahna pangngai mai a ni lo. Nilengin i chau lutuk a, engmah i ti thei lo. Khum atanga tho pawh i hre lo mai thei.
• Anorexia (ei duhna hloh): Ei duhna hloh. Chaw chu hmuh tur a awm tawh lo va, a thlum bawk. Hei hi ei leh in lama harsatna Anorexia Nervosa tih nen a danglam a ni . Hei hi natna avanga ei duhna a tlakchhamna dinhmun a ni.

Engvangin nge Cachexia hi a lo awm?

A awlsam zawngin, cachexia hi kan taksa chakna mamawh leh ei leh in atanga kan hmuh chakna inzawmna a tihbuai hian a lo awm thin. A chhan ber chu natna khirh tak, cancer emaw, thinlung natna emaw a awm vang a ni.

Ngaihtuah teh, natna khirh tak i neih chuan i immune system chuan chu natna chu a do tan ta a ni. Tichuan i taksa metabolism a chak zawk thin. Chumi awmzia chu i taksa hian a hma aia chakna a mamawh zawk tihna a ni. Mahse, chu natna avang chuan i ei duhna pawh a tlahniam thei bawk.

Chuti a nih chuan, chaw atanga chakna i hmuh tlem chuan i taksa hian eng nge a tih? I taksa ruh leh thau awmna atang hian chakna a la tan thin. Chuvang chuan i thau a tlahniam a, i taksa ruh te pawh a hmin vek bawk.

Science lam deuha sawi ila, hei hi a nghawng chhan bik engemaw zat a awm a:

• Cytokines tihpun: Cytokines hi kan immune system-a protein bik a ni. Hengte hian kan taksa hian virus ang chi invader te a do let thin. Mahse, Cachexia-ah chuan heng cytokines te hi an pung nasa lutuk a, taksa pum puiah inflammation a siam thin. Hei hian thau leh thau a tichhe thin.
• System-wide inflammation: He inflammation hi cancer ang chi natna khirh tak tak avanga lo awm hian thau leh thau a tichhe bawk.
• Insulin resistance: Insulin hi kan taksaa thisen sugar control tu hormone a ni. Insulin resistance tih awmzia chu kan taksa thau leh thau cell te hian insulin an dawng tha lo tihna a ni. Cachexia-ah chuan he natna hian taksa ruh a tichhe zual thei a ni.
• Protein turnover tihpun: Kan cell-ah hian protein hlui aiah protein thar siamna process a awm a. Hei hi protein degradation an ti bawk . Cachexia-ah chuan heng protein te hi an inthen darh chakna chu a thar siam chakna aiin a pung chak zawk a ni. Chumi awmzia chu taksain protein thar a siam aiin protein a hmang tam zawk tihna a ni. Hei hi taksa ruh chak lohna thlentu lian tak a ni bawk.

Cachexia nen hian eng dinhmun nge a inzawm tam ber?

Cachexia hi cancer vei zingah hmuh tur a tam ber. Zirna hrang hrangah cancer vei zinga 40% vel chuan he natna hi an hriat hmasak ber ṭumin cachexia an nei a, cancer natna zual emaw, a hnuhnung zawk emaw vei zinga 70% vel chuan cachexia an nei bawk.

Mahse, he natna hi cancer vei te chauh ni lovin, natna khirh tak tak dang nei te tan pawh a awm thei a ni. Entirna tlemte chu hetiang hi a ni:

• Congestive heart failure: Heart failure nei zinga 16% leh 42% inkar chuan cardiac cachexia an nei thei.
• Chronic obstructive pulmonary disease (COPD): Cachexia hi COPD vei zinga 27% atanga 35% ah a awm thin.
• Chronic kidney disease (CKD): He natna hian CKD vei zinga 30% leh 60% inkar a vei a ni.
• Natna hrik kai theih thenkhat: Entirnan, AIDS (Acquired Immune Deficiency Syndrome) .Cachexia hi natna a zual zel angin a awm fo thin. Tuberculosis leh malaria ang chi natna vei teah pawh a lo awm thei bawk.
• Chronic inflammatory diseases: Inflammatory joint conditions nei zinga 18% leh 67% inkar, rheumatoid arthritis , te hian cachexia an vei a rinawm.

Cachexia natna hian eng harsatna nge a thlen?

Cachexia hi nunna atana hlauhawm tak a ni. Hei hi han ngaihtuah teh, Cachexia hi cancer thihpui zinga 20% vel a ni. A chhan chu taksa ruh (muscle wasting) a thlen hian thinlung leh thawkna a nghawng thei a ni.

A tlangpuiin cachexia hmuhchhuah a nih chuan nun tawp hun a hnai tawh tihna a ni. Hei hi thu hriat harsa tak a ni a, damlo tan pawh, an hmangaih tak takte tan pawh. Tin, rilru lam harsatna, lungkhamna leh lungngaihna a thlen thei bawk.

Cachexia hian taksa rihna a tihniam a, hmel a tidanglam a nih chuan mi thenkhat chuan mualpho leh lungkhamna an nei thei. I taksa chak lohna avanga mahni hna thawh theih loh hi a pawi hle bawk.

Research atanga a lan dan chuan cachexia vei leh an enkawltute inkarah hian inzawmna nuam lo tak tak a awm thei a ni. I hmangaih tak chu a cher a, a chak lo a, a zalenna a hloh lai en chu a harsat zia han ngaihtuah teh. A chang chuan, enkawltute chuan, "Chaw tlem ka pek belh mai chuan hei hi ka thunun thei ang," tiin an ngaihtuah thin. Mahse, damloin chaw a ei duh loh chuan an lungngai a, an thinrim bawk. He chaw ei tura nawrna hian chhungkaw inkhawm pawh a ti nuam lo thei hle. Damlo ṭhenkhat chuan mikhual an lo kal hian muhil ang maiin an insiam a, ei tûr an nawr luih theih beiseiin an awm a ni.

Engtin nge Cachexia hi hmuhchhuah a nih?

Doctor-in a tih hmasak ber tur chu taksa enfiahna a pe che a ni. I hriselna tlangpui, damdawi lam harsatna dang i neih dan te, a bik takin i cachexia thlentu damdawi rei tak i ei leh ei loh te an zawt ang. I taksa hriselna leh thau chakna enfiah nan test an ti thei bawk. Thisen test pawh an ti thei a, chu chu Comprehensive Metabolic Panel (CMP) , leh CT (Computed Tomography) scan .

Cachexia hi engtin nge enkawl a nih?

Dik tak chuan cachexia hi enkawlna bik a la awm lo. Doctor-te chuan cachexia thlentu underlying condition enkawl hi an ngaih pawimawh ber a ni. Chumi awmzia chu cancer, thinlung natna emaw, natna dang reng reng enkawl hi a pawimawh ber tihna a ni.

Chu bâkah, ei duhna i neih chuan i ei tûr tihpun dân tûr i rawt thei bawk.

Entîr nân, doctor-te chuan protein, thau, leh calorie tamna ei tûr, a tê tê, ni khatah vawi engemaw zât ei tûrin an rawt thei a ni.Vawikhatah chaw lian tak i ei thei lo a nih pawhin ni khatah vawi eng emaw zat chaw te zawk ei hian calorie tam zawk i neih theih nan a pui ang. Kum khat chhunga he hun atana ei tur tha leh i ei apiang i hman tangkai theih dan tur te chu i nutritionist nen inbiakna neihpui a tha.

Cachexia damdawi a awm em?

Tunah hian cachexia damdawi bik pawm a la awm lo. Research thenkhatah chuan damdawi megestrol acetate hian ei duhna a tipung thei a, taksa rihna engemaw zat a tipung thei niin an sawi a, mahse US Food and Drug Administration (FDA) chuan cancer vanga cachexia enkawlna atan a la pawm lo. A then phei chuan doctor-te chuan hun rei lote chhung atan damdawi corticosteroid ang chi an pe thei bawk.

Enkawltuten eng nge an tih theih?

Cachexia vei i enkawl a nih chuan hei hi hriat reng a pawimawh: Natna khirh tak avanga cachexia a lo awm chuan taksa a metabolism a chak a, chuvangin damlote chuan riltam an ti lo. Chuvangin, calorie tam zawk i pek pawhin , cachexia dinhmun chu a tha reng lo. Force -feeding hian natna lan chhuahna a tipung chauh a, chu chu rilru hahna leh luak chhuak te hi a ni. Hei hian damlo chu a ti nuam lo zual sauh a ni.

Chuvângin, i hmangaih chu chaw ei tûra nawr luih ai chuan, thlamuan dân dang ngaihtuah la. Entirnan, thil tenawm tak tak, a chang chuan massage pek te, an taksaah lotion engemaw zat hnawih te, emaw, an hmui a vawt chuan moisturizer hnawih te hi a thlamuanthlak hle thei a ni. Tin, anmahni biak leh an thusawi ngaihthlak hi i tan a pawimawh hle bawk.

Cachexia ka vei a nih chuan eng nge ka beisei ang?

Hetiang natna hi i neih chuan natna khirh tak, thihpui thei khawpa natna i vei tawh mai thei. I dinhmun azirin cachexia i vei tih hmuhchhuah a nih chuan i nun tawp lam i hnaih tawh tihna a ni thei. Mahse, cachexia thlen thei dinhmun tam tak a awm avangin i dinhmun hi midang dinhmun nen a danglam vek thei. Chuvangin, i beisei tur hriat dan tha ber chu i healthcare team te nen inbiakna neih hi a ni. An hnenah inhawng takin awm rawh.

Engtin nge ka in enkawl ang?

Cachexia nena nun dan tur kaihhruaina chiang tak awm lo mah se, heng rawtnate hian a pui thei che a ni:

• Chaw ei \ha (mahse nawr luih suh): Chaw ei i duh hunah ei rawh. Mahse, ei ngei ngei tur a nih avangin in nawr luih suh.
• Chaw tenau zawk ei tum: I stress lai hian chaw lian tak ei i duh lo mai thei. Chuvangin, ni khatah vawi tam tak calorie tamna ei tur tlem zawk ei tum ang che. Chaw ei tur ngaihtuahna chungchangah i nutritionist nen inbiakna neihpui rawh.
• Exercise light tak ti rawh:A theih chuan exercise light tak tak tih hian i taksa ruh a tichak thei a ni. Kal mai mai emaw, i kut leh ke tlemte i tihchet emaw pawhin a ti thei ang.
• Mental health support dawng rawh: Hetiang natna khirh tak nei te hian stress leh depression an nei fo thin. Chuvangin, he thil chungchangah hian i medical team-te tanpuina dil hreh ngai suh.
• Palliative care ngaihtuah rawh: Palliative care hi enkawlna bik a ni a, i natna lan chhuah dan leh enkawlna avanga a side effects te enkawl nan a pui thin.
• Hospice support chungchang zawt rawh: I medical team hnenah hospice support chungchang zawt rawh. Hei hian thlarau lam thurawn petu leh khawtlang tana thawktute ang mite thlawpna a huam thei a ni.

Tube feeding hi cachexia damdawi a ni em?

Doctor-te chuan cachexia tan hian enteral feeding leh parenteral nutrition hi an rawt tlangpui lo a, heng enkawlnate hian cachexia a tichak emaw, dam chhung a ti rei thei tih finfiah a la ni lo.

Tube feeding chu hnar kaltlanga, pum chhunga direct emaw, small intestine chhunga dah luh, flexible tube hmanga liquid nutrition pekna a ni. Parenteral nutrition chu IV line hmanga vein chhunga direct-a nutrition pekna a ni.

A tawp berah chuan hriat reng tur (Take-Home Message) .

Cachexia, a nih loh leh Wasting Syndrome tih hi natna khirh tak tak, a bik takin cancer natna zual leh thinlung natna nei te tan a ni. Vawi tam tak chu nun tawp ber zinga mi anga ngaih a ni. Hei hi hriat tur lungchhiatthlak tak a ni tak zet a, cachexia i vei emaw, cachexia nei mi i enkawl emaw pawh nise. I doctor-te chuan cachexia hian i nitin nun a tihbuai theih dan leh i rilru hriselna a nghawng theih dan an hre chiang hle. Hetiang dinhmunah hian i awm a nih chuan engmah khap tlat suh la, i medical team hnen atangin mental health support dil rawh. Nangmah chauh i ni lo tih hre reng ang che. A pawimawh ber chu hei hi hriat chian a, hriatthiam a, i mamawh tanpuina dawng tur a ni.

` cachexia, wasting syndrome, emaciation, taksa tihchhiat, cancer, natna rei tak, taksa rihna tlahniam, taksa ruh hloh, ei leh in, ei leh in ei loh