Zing lamah i ruh natna khauh tak, hring dup leh tuar theih loh nen i tho thin em? I khup leh i kekawrte ang chi i ruhte chu a na em? I doctor chuan damdawi chi khat ‘DMARDs’ tih chu tan tir turin a hrilh che pawh a ni mai thei. Chu hming i hriat khan hlauhna tlem i nei em? ‘Hei hi eng damdawi nge ni?’ tiin i ngaihtuah em? Lungngai suh. Vawiin hian heng DMARD te hi i hriatthiam theih tur khawpa awlsam takin kan sawi dawn a ni.
A awlsam zawngin DMARD hi eng nge ni?
Kan taksa chhungah hian vengtu fing tak a awm tih han ngaihtuah teh. He guard hi immune system kan ti a . A hna ber chu pawn lam atanga taksaa lut natna thlentu hrik (virus leh bacteria ang chi) do a, natna laka min humhim hi a ni.
Mahse, a chang chuan, a tlem hle a, he kan vengtu hian tihsual tlemte a nei thin. A taksa ngeia cell hrisel tak tak, a bik takin kan ruhkawr ang hmuna awmte chu hmelma niin a ngai a, a bei tan ta a ni. Mahni inah lung a vawm ang mai a ni. Hetiang dinhmun hi autoimmune disease kan ti a .
Hei hi damdawi chi khat DMARD tih hming pu a lo lut a, DMARD hi ‘Disease-Modifying Antirheumatic Drugs’ tihna a ni. A hming hi a sei deuhin a lang thei a, mahse a takah chuan a awlsam khawp mai. Heng damdawi te hian an tih chu a ti thlamuang a, a control a, chu chu a taksa a thawk nasa lutuk a, a taksa ngei pawh a bei thin.
He damdawi hian kan taksa tan hlawkna lian tak tak a pe a, chungte chu:
- Ruh chhunga inflammation leh swelling a tiziaawm.
- I natna chu i thunun thei a ni.
- Natna darh zelna emaw, a nasat dan emaw a tikhawtlai a ni.
- Ruh leh ruh chhiatna awm reng tur a tihtlem emaw, a veng emaw.
- I ruh (joint) te a thawk tha reng a, nitin hna i thawh theih nan a pui bawk.
DMARD hi eng natna atan nge hman a nih?
Doctor-te chuan heng damdawi, DMARD tia koh, autoimmune natna avanga inflammation control nan an hmang ber a ni. Entirna tlemte chu hetiang hi a ni:
- Rheumatoid arthritis natna a ni
- Ankylosing spondylitis natna a ni
- Psoriatic arthritis natna a ni
- Lupus a ni
- Naupangte zingah hian ruh natna (arthritis idiopathic arthritis) a awm
- Scleroderma a ni
- Multiple sclerosis natna a ni
- Sjögren-a natna (syndrome) a ni
- Myositis natna (Myositis) a ni
- Rheumatoid vasculitis natna a ni
- Inflammatory bowel disease - entirnan, Crohn natna
Hei bakah hian DMARDs hi cancer chi hrang hrang, hmuh tur awm lo thenkhat enkawlna atan pawh hman theih a ni bawk.
DMARD chi hrang hrangte chu engte nge ni?
DMARD te hi group lian pahnih ah then theih a ni. An hnathawh dan leh an hman dan pawh a inang lo deuh.
| DMARD chi khat a ni | A sawifiahna awlsam tak | Entirna hman tlanglawn tak tak te |
|---|---|---|
| Traditional DMARDs te hi a ni | Heng damdawi te hian immune system zawng zawng a nghawng a, a hnathawh a ti tlem a ni. Hetiang damdawi chi hi a bul tan hmasak ber a ni tlangpui. Pill angin an lo thleng fo thin a, chu chu ka atanga ei thin a ni. |
|
| Biologics lam thil a ni | Hengte hi damdawi chi thar, hmasawn tak tak an ni. ‘Guided missile’ ang mai an ni. Natna thlentu immune system cell thenkhat chauh an target a, an bei a, system pumpui an nghawng lo. IV infusion emaw subcutaneous injection emaw angin an pe tlangpui. |
I doctor chuan heng chi hnih zingah hian eng chi nge pek che tur che, a nih loh leh pek tur che tih chu i dinhmun, a nasat dan leh i taksa tana tha ber tur a zirin a rel ang.
Mi zawng zawng hlauhthawn ber thawnthu: Side effects a awm em?
Damdawi dang ang bawkin DMARD hian side effect engemaw zat a nei thei a ni. Mahse he list hian hlauthawng suh. Mi zawng zawng hian heng side effect zawng zawng hi an nei vek dawn lo. I doctor chuan he hlauhawmna hi a tih tlem theih nan a enkawl ang che.
| Side effect chi hrang hrang | Description leh hriat tur te |
|---|---|
| DMARD chi hnih a side effect awm thei | |
| Hri kai theihna a sang zawk | Heng damdawi te hian immune system a tihbuai avangin awlsam takin khawsik leh flu ang chi natna i vei thei a (biologics hmang hian a hlauhawmna a sang deuh hlek a ni). Chuvangin mipui tamna hmuna damlote laka inthiarfihlim a pawimawh. |
| Thisen cell a tlahniam | Thisen var (leukopenia), thisen sen (anemia), leh platelet (thrombocytopenia) te hi a tlahniam thei a ni. Hei vang hian doctor hian thisen test a ti fo ang. |
| Liver enzymes a sang hle | DMARD thenkhat chuan liver a nghawng thei. Hei hi thisen test hmanga enfiah a ni bawk. |
| Traditional DMARDs bik atana side effect awm thei | |
| Gastrointestinal lama harsatna awm thei | Chaw ei chak lohna, luak chhuak, luak chhuak, pum na, leh ril\am a awm thei. |
| Vun a hring chhuak | Mi thenkhat chuan vun rawng an nei thei. |
| Biologics bik atana side effect awm thei | |
| Infection hlui lo awm lehna | Tun hmaa natna, TB, herpes, emaw hepatitis emaw i neih tawh chuan heng damdawi te hian a tichak leh thei a ni. Chuvangin, i doctor chuan damdawi i ei tan hmain hei hi a enfiah hmasa ang. |
| Injection site-a thil thlengte | Injection na hmunah hian a sen, a hring emaw, a na emaw a awm thei. |
A pawimawh ber chu symptom thar emaw side effect thar emaw i neih chuan doctor hnenah hriattir nghal tur a ni.
He damdawi hian hna a thawh theih nan eng chen nge a mamawh?
Hei hi zawhna pawimawh tak a ni. DMARD hi damdawi i ei ruala i ei nghal mai, natna tidamtu ang chi a ni lo. Heng damdawi te hi taksaah a luh theih nan hun rei tak a ngai a, immune system a control a, result a lantir bawk.
- Traditional DMARD te hian thla khat emaw a aia rei emaw an thawk thei a ni.
- Biologics te hian kar tlemte chhungin hna an thawk tan tlangpui .
He damdawi i ei tan tirh hian a natna chu a reh nghal lo a nih chuan lungngai suh. Results hmuh tur hian hun rei tak a ngai a, chuvangin dawhtheih a pawimawh. I doctor chuan chutih lai chuan natna control turin damdawi dang a pe ang.
Engtikah nge doctor ka hmuh leh ang?
DMARDs i tan tirh chuan i doctor chuan a lo enkawl reng ang che. Chuvangin a hun taka clinic pan a pawimawh. A tlangpuiin a hnuaia mite hi i tawng ang:
- Thisen test neih fo: Damdawi hian a thawk tha em tih leh side effect (thisen cell count, liver function) a awm em tih enfiah nan thisen test mumal tak nei turin an ti ang che.
- Infection awm leh awm loh enfiah: Infection i neih leh neih loh enfiah fo tur a ni a, a bik takin biologics i ei a nih chuan.
- X-ray ang chi test: X-ray ang chi test hi a hun hunah tih theih a ni a, ruh ruh a chhiat leh chhiat loh enfiah theih a ni.
Side effect thar i neih chuan, damdawi chuan hna a thawk lo ang maia i hriat chuan, emaw, i natna lan chhuah dan a zual deuh a nih chuan, i doctor nen inbiakna neih nghal la, clinic appointment lo awm tur chu nghak ngai lovin.
DMARDs hi damdawi class hlauhawm leh buaithlak tak angin ri mah se, i natna thunun thei a, ruh chhiatna a veng thei a, nun pangngaia i nun theih nan a pui thei bawk. I doctor chuan i tan damdawi combination dik tak a thlang ang. Chuvangin i doctor hnenah zawhna i neih apiang zawh hreh suh.
Take-Home Thuchah a ni
- DMARDs hi natna tidamtu a ni lo. I natna bulpui ber, overactive immune system control tu damdawi an ni.
- Heng damdawi te hi a hman theih nan kar engemaw zat emaw thla khat emaw pawh a ngai thei a, chuvangin dawhtheihna hi a pawimawh hle.
- Side effect awm thei mahse, i doctor chuan thisen test mumal tak hmangin uluk takin a enkawl ang che.
- Damdawi ei kha chawlhsan ngai suh la, doctor thurawn tel lovin a dose pawh thlak ngai suh.
- Thil danglam bik (khawsik, khuh, hri kai dang) i neih chuan doctor hnenah hriattir nghal rawh.
- Dik taka hman a nih chuan DMARDs hian i nunphung nasa takin a tichangtlung thei a ni.
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