I naupang tê chu a rawn inher ṭan nghal em? Hei hi Infantile Spasms kan tih hi a ni em? I zawng chhuak ang u!

I naupang tê chu a rawn inher leh a nghet lo tih i hmu ngai em? Hei hi ni khatah vawi tam tak a thleng mai thei. Hei hi thil pangngai a ni em tih emaw, naute nghawng thei dinhmun bik a ni em tih emaw i ngaihtuah mai thei. Chu chu vawiinah kan sawi dawn a ni. Hetiang dinhmun hi `(Infantile Spasms)` an ti a. Eng nge a nih, engvanga lo awm nge a nih, a natna lan chhuah dan te, engtin nge a hriat theih ang tih te, a enkawl dan tur te i lo en ang u.

Hei hi eng nge ni (Infantile Spasms)?

A awlsam zawngin, `(Infantile Spasms)` hi epilepsy chi khat a ni a , naute kum khat hnuai lam, chu chu thla 12 hnuai lam a ni . Epilepsy hi i naute thluak electrical activity-a harsatna pangngai lo avanga lo awm (`neurological disorders`) a ni. Heng `(Infantile Spasms)` te hi a lo awm hian naute taksa, a bik takin a pum, lu, kawr, kut leh ke te chu a nghet nghal a, a chet ang maiin a lang.

Heng inzawmnate hi hun rei lote chhung, second khat emaw, second hnih emaw vel a ni . Mahse series-ah an awm thei a, chu chu contraction pakhat a lo thleng a, chutah second 5 emaw 10 emaw hnuah a dang emaw, `cluster`-ah emaw a awm thei tihna a ni. Naute pakhatin a zawnin vawi tam tak a kick lai han mitthla teh. A tam zawkah chuan heng contraction te hi naute mut atanga an harh hnuah a lo awm thin .

Thil lungchhiatthlak tak chu, he natna vei naute tam tak hian an thanlenna kawngah harsatna an nei tawh mai thei a, a hnuah pawh an nei thei bawk. Chu chu naute hian an kum nena inmil thil a ti tlai tihna a ni.

(Infantile Spasms) leh (West Syndrome) hi eng nge an danglamna?

Tunah chuan he ``West Syndrome'' hi eng nge a nih i ngaihtuah mai thei. A chang chuan Doctor te pawhin hetiang hian an ko thin. ``West Syndrome'' hi symptom engemaw zat awmna a ni. Chu chu:

• He ``Infantile Spasms'' kan sawi hi kan nei a.
• Thluak electrical waveform-ah hian thil danglam tak `(Hypsarrhythmia)` tih a awm a. (Hei hi `(EEG)` test hmanga hmuhchhuah a ni a, a hnuah kan sawi leh ang).
• Hmasawnna tlai emaw, a hmaa theihna awmsa hloh (`developmental regression`) a awm.

Amaherawhchu, nausen `(Infantile Spasms)` vei zawng zawng hian `(West Syndrome) an nei vek lo.

Spasm leh seizure hi eng nge an danglamna?

Ni e, hei hi zawhna pawimawh tak a ni. `(Infantile Spasms)` hi a takah chuan seizure chi khat a ni. ``Seizure`` chu thluak cell inkara electrical activity rang tak, thunun theih loh a ni. Hei hian hun engemaw chen chhung chu taksa ruh a tikhauh thei a, chetna, nungchang a tidanglam thei a, hriatna lama danglamna danglam tak a thlen thei bawk. Seizure zawng zawng hi a inang vek lo.

Seizure kan ngaihtuah hian kan ngaihtuah fo thin tonic-clonic emaw grand mal seizures te nen khaikhin chuan heng infantile spasm te hi a tawi zawk hle. Infantile spasm hi second khat emaw second hnih emaw vel a ni a, mahse cluster-ah a lo awm thin. Seizure chi dang hi second 30 atanga minute hnih vel thleng khawi hmunah pawh a awm thei.

Infantile Spasms leh Startle Reflex hi eng nge an danglamna?

Hei hi nu leh pa tam tak tibuaitu a ni bawk a, a chhan chu ``Infantile Spasms'' lo lang dan hi naute inhnim hrual tlangpui nen a inang thei a ni.

Naute chu thawm ri nasa tak an hriat emaw, an che nghal mai emaw hian an mangang tlangpui (Moro reflex an ti bawk). Chutah naute chuan an lu chu hnunglam a thlak a, an kut leh ke chu zau takin a phar a, an lu chu chunglam hawiin a han her kual a. A châng chuan an ṭap thei a, chutah chuan an kut leh ke chu an taksa lamah an hruai kir leh mai thei.

Mahse `(Infantile Spasms)` ah chuan chutiang pawn lam thil a awm lo . Chu chu, a ri emaw, thil dang emaw avanga spasm te hi a awm lo tihna a ni. A dang chu `(Infantile Spasms)` hi cluster hrang hranga lo awm a ni . Chu chu pakhat a lo kal a, chutah pakhat a lo kal leh a, pakhat a lo kal leh tihna a ni. Spasm pangngai chu chutiang chuan a daih lo. Tin, spasm a lo awm chuan naute mit chu a roll up thei a, a nih loh leh a mitmeng a ti hrual ang maiin a lang thei bawk . Hengte hi spasm pangngaiah chuan a tam lo hle.

Kum engzat nge nausen spasm hi a intan?

Doctor-te sawi dan chuan `(Infantile Spasms)` 90% chu nausen thla 12 hnuai lam, chu chu nausen kum khat hnuai lam atanga hmuhchhuah a ni. Kum li leh thla sarih inkar vel a ni tlangpui . Mahse, a chang chuan naupang thla 12 chunglam pawhin hetiang spasm hi an nei thei bawk. Chutiang a nih chuan `(Epileptic Spasms)` tiin a thliar hrang a ni.

Hetiang dinhmun hi engtiang chiahin nge a awm?

Hei hi thil awm dan tlangpui a ni lo va, mahse awm lo pawh a ni lo. Naute 2,000 atanga 4,000 zinga pakhat vel chu he natna (Infantile Spasms) hian a vei thei niin an chhut.

Infantile Spasms hi eng symptoms nge ni?

Heng contraction te hi a lo thlen hian i naute taksa chu a nghet nghal a, a nih loh leh a jerk nghal bawk. Second tlemte chauh a daih. Naute chuan an hnungzang a arch thei a, a kut, a ke a ben thei a, hmalam a pan thei bawk. Kan sawi tawh ang khan heng contraction te hi cluster-ah an lo awm a, pakhat hnu pakhatin second 5-10 chhung break an nei a ni.

Kick emaw, kick tlemte emaw hnuah naute chu a buai thei a, a tap thei bawk. Mahse chutiang chu a thleng ngai lo.

A chang chuan heng `(Infantile Spasms)` te hi a fiah lo hle thin . Anmahni chu awlsam takin kan hre lo pawh a ni thei. Chutiang chhinchhiahna fiah lo tak takte chu:

• I mit chu a rawn roll a.
• Pum natna.
• Chin che vel.
• A nui suk a.
• Lu a bu nghat a.

Naute thluaka thil dik lo avanga khur a nih chuan taksa peng khat chauh a nghawng fo thei. A nih loh leh lu emaw mit emaw chu a sir khatah hrual ang maiin a lang thei bawk.

A pawimawh ber chu he kick hi naute mut atanga a harh hnuah a thleng tam ber a ni . Naute mut laiin a awm tlem hle.

Heng kick te hi a tan hnu rei vak lovah i nauteah hian inthlak danglamna dang i hmu thei ang:

• Hmasawnna atana thil pawimawh tak tak, rolling over, thut, khup, leh babbling te chu a bo ta a ni.
• Mi dangte nena inpawh tawnna a tlahniam a, nuih pawh a tlahniam bawk .
• Hlauthawng reng, a nih loh leh ngawi reng reng.

A theih chuan i naute hian heng spasms te hi a neih hunah videotape la . Chumi hnuah chuan i pediatrician hnenah i entir thei ang. Heng ``Infantile Spasms'' te hi hriat hmasak a pawimawh hle. I naute hian heng spasms te hi a nei nia i hriat chuan a rang thei ang bera doctor pan rawh.

Nausen spasm hi eng chen nge a awm theih?

Naute hian ni khatah seizure 100 thleng a nei thei. Mahse naute tin hian a nghawng dan a inang lo. Chuvângin, i naute chu ni khatah vawi khat emaw, vawi hnih emaw chauh pawh ni se, seizures a nei tih i hriat chuan, a rang thei ang bera doctor biak a ṭha ber .

Infantile Spasms hi engte nge ni?

Nausen hnim hring (nausen spasm) thlentu awm thei tam tak a awm. Scientist-te chuan hriselna lama harsatna awm thei 200 chuang an hmuchhuak tawh a ni. Mahse, hmun thuma ṭhena hmun khat vêlah chuan doctor-te chuan a chhan dik tak an hmu thei lo.

He stroke hi naute thluak hmun tlemtea thil danglam vang a ni thei a, a nih loh leh thluak pumpuiah harsatna awm vang a ni thei bawk.

A chhan lian ber thenkhat chu:

• Brain damage or infection: He stroke hi thluak hliam chi hrang hrang avanga lo awm thei a ni. A chhan ber chu `(Hypoxic-ischemic encephalopathy)` (chu chu thluak hian oxygen emaw thisen emaw a hmu rei lo tihna), `(Meningitis)` (meningitis), leh `(Perinatal stroke)` (naute naupai lai leh a pian hnu thla khatna chhunga stroke awm tihna a ni).
• Brain Development Problems: Hei hi naute chu nausen pum chhunga a lo thanglian zel laiin central nervous system (brain leh spinal cord)-a thil danglam engemaw zat a awm vang a ni thei. Entirnan, `(Focal cortical dysplasia)`, `(Lissencephaly)`, `(Holoprosencephaly)` leh `(Aicardi syndrome)` ang chi natna te hi a ni. Naute thluaka thisen kalna kawng dik lo (`(Arteriovenous malformations)`) vang pawh a ni thei.
• Gene mutations: Tunah chuan scientist-te chuan gene mutations tam tak chu nausen spasm nen an inzawm tir ta a ni. Entirna thenkhat chu Trisomy 21 (Down syndrome), Tuberous sclerosis, Miller-Dieker syndrome, leh CDKL5 tlakchhamna natna te hi a ni.
• Metabolic conditions: Inborn errors of metabolism (IEM) pawhin he natna hi a thlen thei bawk. Hengte hi kan ei tur tichhetu leh chakna siamtu metabolic pathways tikhawlotu genetic conditions an ni. A tlem hle a, vitamin B6 tlakchhamna hian hetiang dinhmun hi a thlen thei bawk.

Engtin nge Infantile Spasms hi hmuhchhuah a nih?

I naute doctor chuan i naute natna lan chhuah dan leh damdawi lam chanchin a zawt ang che a, taksa enfiahna pawh a nei ang.

Chumi hnuah i naute chu pediatric neurologist emaw epileptologist emaw hnenah hruai theih a ni. Naute hian infantile spasms a nei em tih finfiah nan electroencephalogram (EEG) an ti ang. A chhan hriat tumin test dang pawh an ti thei bawk.

`Infantile Spasms` hi chhan za tam tak a awm theih avangin doctor tan chuan a chhan zawn chu a harsa deuh thei a ni.

Diagnostic test te hi engte nge ni?

Doctor hian ``Infantile Spasms'' a awm leh awm loh finfiah nan ``Electroencephalogram - EEG'' test a ti ber a ni.

EEG hian i naute thluaka electrical signal awmte chu a teh a, a record bawk. EEG an tih hian technician pakhatin naute lu vunah hian thir plate te (electrode) a dah a. Heng electrode te hi machine nen an inzawm a ni. Machine hian naute thluak hnathawh dan tur chu doctor hnenah a pe a. EEG laiin naute hian seizure a neih chuan a tha ber a, seizures inkar hun chhung hi record theih a ni. Doctor-te chuan EEG pattern bik, hypsarrhythmia an tih chu an zawng a. He pattern hi a chiang hle. Hei vang hian doctor-te tan chuan nausen natna (infantile spasm) dik taka hriat a awlsam fo thin.

Doctor chuan he khur chhan hriat nan test dang neih belh a ti thei ang:

• Magnetic resonance imaging (MRI) scan of the brain: MRI scan hi natna nei lo test a ni a, i naute thluaka tissue leh structure te chu chiang takin a hmu thei a ni. MRI hian magnet lian tak, radio wave leh computer hmangin heng thlalak chipchiar tak takte hi a siam a ni. X-ray a hmang lo. MRI hian i doctor chu i naute seizures awm chhan a hriat theih nan a pui thei a ni.
• Genetic leh metabolic test: I naute MRI hi a pangngai a nih chuan i doctor chuan test dang, genetic leh metabolic test te chu a ti fo ang a, a seizures awm chhan zawn chhuah a tum ang. Heng test-naah hian thisen, zun emaw, ruhro tui emaw sample lak a ngai tlangpui.

Infantile Spasms hi engtin nge an enkawl?

Enkawlna kawngah hian tum lian tak pahnih a awm a. Pakhat chu stroke tihtawp emaw control emaw hi a ni . A dang chu stroke thlentu enkawl a ni , a theih chuan.

Seizures tihtawp emaw enkawl dan tur enkawl dan tlangpui chu:

• Adrenocorticotropic hormone (ACTH) hmanga siam chhuah a ni a:ACTH hi i pituitary gland atanga hormone siam a ni. I taksain stress a dawn danah nghawng lian tak a nei a ni. ACTH a chhuah chuan adrenal glands te chu an tichak a, "stress hormone" cortisol an siam chhuak thin. ACTH hi seizure enkawlna atana hman thin a ni a, synthetic hormone a ni. Injection angin pek a ni. Dose hmasa tlemte chu damdawi inah pek thin a ni. Chumi hnuah chuan doctor chuan i naute chu a side effect awm thei leh awm loh uluk takin a enfiah ang. ACTH injection hi kar ruk vel a chhunzawm dawn avangin i doctor chuan i naute chu in lama injection pek dan tur a hrilh ang che.
• Oral prednisolone: ​​He damdawi hi adrenal glands atanga siam corticosteroid hormone siam chhuah a ni. Nausen spasm enkawlna atan a thawk tha hle. ACTH hmuh harsat lai pawhin hman theih a ni.
• Vigabatrin (`Vigabatrin - Sabril®`): Hei hi mittui tlakna damdawi a ni. Pill emaw liquid emaw angin ka hmanga pek a ni.

I naute hian heng hormonal treatment emaw Vigabatrin emaw a chhan loh chuan enkawlna dang a awm a:

• Ketogenic diet a ni.
• Anticonvulsant damdawi dang.
• `Infantile Spasms` awm chhan hi thluaka hmun khata harsatna awm (`focalized lesion`) a nih chuan epilepsy surgery neih a tha.

Infantile Spasms hi a chang chuan enkawl harsa tak a ni thei. Naupang thenkhat chuan enkawlna kawng khat emaw, enkawlna vawi hnihna emaw an tih nawn leh a ngai mai thei. Enkawlna neih chhung zawng hian naute thluak hnathawh dan chu EEG test nawn leh a, enkawlna hian a thawk tha em tih enfiah a ngai mai thei.

Doctor-in naute fussiness chhan a hmuh theih chuan a theih chuan chu chhan chu an enkawl tur a ni. Hei hian surgery emaw targeted therapy emaw a awm thei a, chu chu underlying genetic emaw metabolic condition emaw a ni thei.

Infantile Spasms-ah hian hmasawnna tihkhawtlai leh regression hi a awm fo thin. Naute medical team chuan a theih ang anga hmasawnna atana pui thei tur therapies an rawn rawt ang.

Infantile spasms enkawlna hian eng side effect nge a neih?

Adrenocorticotropic hormone (ACTH) hmanga enkawlna hian side effect engemaw zat a nei thei a:

• Thisen sang (Hypertension).
• Immune system chak lohna (`(Immunosuppression)`).
• Swelling (hmaiah a awm fo).
• Restlessness leh thinrimna.
• Pum leh/ emaw intestinal ulcer awm thei.
• Zun atanga glucose paih chhuah.

`Vigabatrin` enkawlna avanga nghawng tha lo awm thei te:

• Hmuh theihna hmun (field of vision) chu tihdanglam theih loh khawpa tihtlem.
• Thinrimna.

Heng side effects te avang hian i naute doctor chuan a biak ang che a, enkawlna tha ber tur a ngaihtuah ang. Tin, i naute chu uluk takin an enfiah ang a, heng side effects te hi a awm em tih an enfiah bawk ang.

Infantile Spasms hi eng prognosis nge ni?

He dinhmun, a nih loh leh `prognosis` hmalam hun hi thil engemaw zatah a innghat a ni:

• `(Infantile Spasms)` awm chhan.
• A chhan chu enkawl theih a ni em?
• Engtiang chiahin nge naute chu a natna hmuhchhuah a nih a, enkawl tan a nih.
• Naute hian kick tan hmain developmental milestone a thleng tawh em tih.

Naupang nausen riltam zinga 50% vel chuan hun rei tak chhung an thanlenna leh an thluak lam harsatna an nei thei a ni. Spasms te hi a tawp a nih pawhin naupang tam tak chuan seizure chi dang leh epilepsy an nei thei a ni.

Mahse, rang tak leh hlawhtling taka hmuhchhuah a, enkawl a nih chuan a pumpui thlirna chu a tha thei a ni . Naupang, seizures lo awm hmaa hmasawnna lama thil thleng (developmental milestones) te chu a pangngaiin an lo thanglian thei a ni.

Engtin nge ka fa nausen riltam (infantile spasms) nei hi ka enkawl ang?

I naute hian ``Infantile Spasms'' a neih chuan doctor thupek zawm la, a tanpui tur a ni:

• Damdawi zawng zawng chu a pek angin pek vek tur a ni.
• Hmasawnna tehfung leh enkawlna te en rawh.
• Follow-up medical visit zawng zawngah kal rawh.

Infantile Spasms hian hriatna, thluak lam, leh/ emaw hriatna lama harsatna a thlen thei a ni. Infantile Spasms vei naupang tam tak chuan hmasawnna lama harsatna an nei a, an dam chhungin nitin hnathawhnaah tanpuina an mamawh mai thei.

I naute medical team chuan i zawhnate chu an chhang thei a, tanpuina an pe thei bawk che. I awmna hmuna support group-te emaw, online emaw-ah emaw an hruai thei bawk che a ni.

Engtikah nge ka fa doctor hnenah infantile spasms chungchangah ka hmuh ang?

I fa chu Infantile Spasms a vei tih hmuhchhuah a nih chuan an medical team te chu an hmuh fo a ngai ang a, chu chu enkawlna a thawk tha em tih hriat chian a ngai ang. Tin, enkawlna hun chhung zawnga thluak hnathawh dan enfiah turin electroencephalogram (EEG) test an neih a ngai dawn bawk.

I naute hian Infantile Spasms a nei nia i ngaih a, mahse a la hriat loh chuan a rang thei ang bera doctor pan a pawimawh hle .

I naute chu a che dan pangngai lo emaw, a hmasawnna tur milestone a tlin loh emaw hian lungkhamna i neih hi thil pangngai a ni. I naute hi i hre chiang ber . I naute hian spasm a nei nia i ngaih chuan - a rang thei ang bera, a khauh, a hrual, a tam zawkah chuan cluster-a awm - doctor hnenah a rang thei ang bera sawipui rawh. A theih chuan spasm video la rawh. Doctor hnenah i entir thei bawk. ``Infantile Spasms'' hriat hmasak hian result tha zawk a thlen thei .

He thawnthu atang hian kan hriat reng tur thil (Take-Home Message) .

Okay, chuvangin kan sawi tawh atanga kan hriat reng tur tlemte chu hetiang hi a ni:

• Infantile Spasms hi epilepsy na tak chi khat a ni a, naute thla 12 hnuai lam a awm thin.
• I naute chu a hrual nghal a, a nghet lo a nih chuan, a bik takin a harh hnuah cluster-ah , chu chu ngaihthah suh .
• Hei hi naute startle reflex pangngai nen a danglam hle.
• A theih chuan a contraction te chu video-ah la la, doctor hnenah entir rawh .
• A hmaa hriatchhuah leh enkawl hian naute hmalam hun atana nghawng lian tak a nei thei a ni.
• I naute nungchang, nuihzatthlak leh thanlennaah inthlak danglamna i hmuh chuan chu chu i doctor nen pawh sawipui rawh.
• Hei hi nu leh pa pahnih tan chuan thil buaithlak tak a ni thei. Chuvangin, doctor thupek dik taka zawm chungin, nangmah tan pawh support la rawh. Lungngai suh, Doctor ten an pui ang che.

` Nausen Spasms, epilepsy, naute hrual, convulsion, West Syndrome, nausen epilepsy, EEG, MRI