Multiple Myeloma hi eng nge ni? He natna khirh tak hi han sawi ila!

Natna Multiple Myeloma tih hi i hre tawh em? A hming hi i tan chuan a mak deuh mai thei, a nih loh leh i la hre lo pawh a ni mai thei. A nihna takah chuan cancer hmuh tur awm lo, mahse na tak, kan thisen tichhe thei a ni. A hriat chian a pawimawh a, a chhan chu a hmaa hriatchhuah hian i natna lan chhuah dan tur a enkawl thei a, i nun tha ber i hmang thei bawk.

Multiple Myeloma hi eng nge ni?

Okay, he multiple myeloma hi eng nge a nih kan en ang. A awlsam zawngin kan thisena plasma cell an tih cell chi khata lo awm cancer a ni.

Tunah chuan, "Heng plasma cell te hi eng nge ni?" Hengte hi kan taksaa thisen var chi khat a ni. Sawi belh zel tur chuan kan immune system , natna laka min humhimtu system-a thil pawimawh tak an ni. A châng chuan hengte hi B-cells an ti bawk. Heng plasma cell te hi antibodies , a nih loh leh immunoglobulins siamtu an ni . Heng antibodies te hi kan taksaa lut hrik, bacteria leh virus te dotu leh natna laka min vengtu an ni. Kan taksaah hian bodyguard te tak te ang mai an ni.

Chuvângin, multiple myeloma a lo awm chuan, heng plasma cell hrisel leh ṭha tak takte hi eng emaw chhanin an inthlâk a, cancer cell pangngai lo tak an lo ni ta a ni . Tichuan heng cell pangngai lo te hi an inthen darh a, an pung chak hle a, thunun theih lohvin an awm ta a ni. Chutianga plasma cell pangngai lo lo piang chhuakte hian antibody pangngai lo, tangkai lo tak tak an siam bawk. Hengte hi M protein kan ti a .

Heng cell pangngai lote hi an pung a, M protein an siam chhuak a, chu chuan harsatna a thlen thei a ni. I ruhte a tichhe thei a, i kal hnathawh a tichhe thei bawk. Tin, ruhro (bone marrow)-in thisen var hrisel, thisen sen (red blood cells) leh platelet siam chhuah theihna a tibuai thei bawk a, chu chuan thisen a tikhawlo thei a ni.

Hei hi tihdam theih loh natna a ni em?

Dik tak chuan tunah hian Multiple Myeloma hi damdawi a la awm lo. Chu chu thudik lungchhiatthlak tak chu a ni. Mahse lungngai suh , doctor ten he natna side effects leh symptoms te hi an enkawl thei a ni. Tin, natna darh zel tur pawh a tikhawlo thei bawk.

Mi tam tak chuan enkawl hnuah symptom nei lovin an dam leh thei a ni. Hei hi remission period kan ti a. Chu chu enkawlna hnuah multiple myeloma symptoms nei lovin i nung pangngai thei tihna a ni. Mi thenkhat tan chuan he remission period hi rei tak a daih thin.

Multiple Myeloma hi engtiang chiahin nge a awm?

Hei hi natna hmuh tur awm lo tak a ni.. Statistics atanga a lan danin kum tin mi 100,000 zinga 7 velin he natna hi an vei thin. America ang ramah chuan he natna hi mi 100,000 velin an vei nia chhut a ni. Kan ramah hian mi engzat nge hri kai tih hi data chiang tak awm lo mah se, hei hi natna hmuh tur awm lo tak anga ngaih a ni.

He natna hi tuin nge vei tam ber?

Multiple myeloma hi hmeichhia aiin mipaah ​​a tam zawk . Hnam thenkhat aiin hnam thenkhat a nghawng nasa zawk tih hmuhchhuah a ni bawk. Entirnan, mipa dumte hian mi var aiin a let hnih zetin he natna hi an vei tam zawk a ni.

Kum lam hawi chuan kum 40 leh 70 inkar mite zingah a awm tam ber a, hmuhchhuah a nih huna kum zat chu kum 65 leh 74 inkar a ni a, chu chu i upa deuh deuh chuan a lang duh tihna a ni.

Multiple Myeloma hian engtin nge taksa a nghawng?

Mi thenkhat chuan a tir lamah chuan symptom an nei lo mai thei a, mahse thisen test ang chi thilte hian nakin lawkah multiple myeloma an vei theihna tur chhinchhiahna a lantir thei a ni.

Entirnan, bone marrow aspiration emaw biopsy emaw hmangin plasma cell pangngai lo leh genetic mutations a lang thei. Hei hian cancer hmaa natna i nei tihna a ni thei a, chu chu smoldering multiple myeloma (SMM) , multiple myeloma hmahruaitu a ni. Thisen leh zun test hian plasma cell pangngai lo atanga siam M proteins te pawh a hmuchhuak thei bawk. Hetiang dinhmun hi monoclonal gammopathy of undetermined significance (MGUS) an ti a. Hengte hi Doctor ten uluk takin an lo enfiah ang che.

Multiple myeloma symptoms hi hun kal zelah a lang zauh zauh thin. Natna dang chhinchhiahna nen an inang thei. He natna avanga natna awm thei lian ber berte leh a chhante chu hetiang hi a ni:

• Anemia: I thisen zam (red blood cells) tlakchhamna a ni. Hei hi a chhan chu plasma cell pangngai lo chuan ruhro a luah khat a, chu chuan thisen sen hrisel tak tak a siam chhuak thei lo a ni.
• Bacterial infection, a bik takin pneumonia: Thisen sen bakah hian plasma cell pangngai lo chu a pung a, infection dotu thisen var hrisel tak takte chu a tichhe vek a ni. Hei hian hri kai a ti awlsam thei a ni.
• Thrombocytopenia: I thisena platelet awm tlem. Platelets hi i thisen zam tura puitu cell a ni. Plasma cell pangngai lo chuan heng platelet siamna hi a tibuai thei bawk.
• Ruh na/ruh tliak: 1.1.Plasma cell pangngai lo chuan ruh tissue a tichhia a, ruh a tichak lo va, a na a, awlsam takin a tikehsawm bawk. Hei hi osteolytic lesions an ti bawk .
• Kidney problems/failure: Kan kidney hian kan taksa atanga bawlhhlawh leh toxins te a filter chhuak thin. M protein hian kal filtering process a tibuai thei a, a tichhe thei bawk.
• Amyloidosis: Hei hi taksa peng hrang hranga protein pangngai lo (amyloid proteins) a awm hian a ni.
• Hypercalcemia: Ruh chhia, chak lo atanga calcium tam lutuk thisenah a awm khawm thin.
• Hyperviscosity syndrome: M proteins hian thisen a ti thim a, chu chu thisen pump tur chuan thinlungin a thawhrim a ngai tihna a ni.
• Cryoglobulinemia: Multiple myeloma hian a chang chuan thisen chhunga protein te chu khawsik laiin a ti khawm thei thin.

Multiple Myeloma natna lan chhuah dan chu engte nge ni?

Multiple myeloma hian symptom hrang hrang a thlen thei. Mahse mi tam tak chuan ruh natna an nei hmasa ber , a bik takin ruh leh ruh natnaah. Symptom dang thenkhat chu hetiang hi a ni:

• Ke ruh leh ke ruh chak lohna leh rilru hahna. Spine chhunga ruh te a chhiat chuan a tlakbuak thei a, spinal cord a press thei bawk.
• Chauhna - Hei hian nitin hna thawk thei lova chau lutuk, chak lo anga inhriat tihna a ni. Hengte hi thisen tlakchhamna chhinchhiahna a ni thei.
• Nausea leh luak chhuak . Hei hi hypercalcemia an tih natna chhinchhiahna a ni thei.
• Chaw ei duh lohna leh/ emaw, a hma aia tuihal zawka inhriatna. Hengte hi hypercalcemia chhinchhiahna a ni thei bawk.
• Sawifiah loh takin taksa rihna tihtlem .
• Sawifiah loh khawpa khawsik . Hei hi bacteria infection chhinchhiahna a ni thei.
• A awlsam zawnga hliam emaw thisen chhuah emaw . Chumi awmzia chu plasma cell pangngai lo vangin taksain platelet a siam tling thei lo tihna a ni.
• Memory loss , ngaihtuahna seng thei lo, "foggy" tih hriat.

Heng chhinchhiahna pakhat emaw pahnih emaw i neih hian multiple myeloma i nei tihna a ni lo tih hre reng ang che. Mahse, heng symptoms te hi a la awm reng a nih chuan doctor pan a, check out a tha ber.

Multiple Myeloma hi engte nge ni?

Doctor leh zirchiangtute chuan multiple myeloma thlentu hi eng nge ni tih chiang takin an la hre lo a, mahse thil engemaw an rinhlelh leh an zirchian mek a awm a:

• Genetic mutations: Kan cells thanna control tu genes ( oncogenes ) thenkhata mutations leh multiple myeloma te hi inzawmna a awm em tih zirchianna neih mek a ni. He natna vei tam tak hian chromosome thenkhat hmun thenkhat an hloh tih hmuhchhuah a ni bawk.
• Environment factors: Zirna thenkhatah chuan radiation, pesticides, fertilizers, leh Agent Orange ang chi chemicals te pawh a tel thei tih hmuhchhuah a ni.
• Inflammatory disease neih: Entirnan, hun rei tak chhunga inflammatory conditions, heart disease, type 2 diabetes, leh rheumatoid arthritis te.
• Obesity: Hei hian taksa thau tam lutuk tihna a ni.

Hengte hi tuna rinhlelh awmte chu a ni. Mahse heng zinga pakhat mah hi a chhan nia finfiah a la ni lo.

He natna hi Doctor ten engtin nge an hriat chian?

Doctor chuan multiple myeloma a hriat theih nan step engemaw zat a zawm thin.

A hmasa berin taksa enfiahna pek i ni ang . I symptoms te chu uluk takin an enfiah ang. I chhungkaw medical history chungchang pawh zawh i ni ang. Tichuan, test eng emaw zat tih a ni thei a, chu chu a natna hmuhchhuah a ni. Heng zawng zawng atanga information kan hmuh hian cancer stage, tumor lian tham leh a darh dan te a hril ang.

Hei atan hian eng test nge tih thin?

Doctor-te chuan multiple myeloma i vei em tih hriat nan test hrang hrang an nei a, a awm a nih chuan a bul tan tirh emaw, a darh deuh tawh emaw an ti bawk. Chung zinga ṭhenkhat chu hetiang hi a ni:

• Complete Blood Count (CBC): Hei hian thisen sen zat, thisen var, leh i thisen sen chhunga hemoglobin awm zat a teh a ni.
• Thisen chemistry test: Hei hian i creatinine level (i kal hnathawh that dan tehna), albumin protein level, calcium level, leh lactate dehydrogenase (LDH) level te a enfiah ang. LDH hi tumor marker a ni thei.
• Quantitative immunoglobulin test: He thisen test hian i thisena antibody chi hrang hrang awm zat a teh thin.
• Electrophoresis: He test hian thisenah M protein awm leh awm loh a enfiah thin.
• Zun test: Darkar 24 chhunga zun sample lakkhawm chu test a ni.Protein dang Bence Jones protein tih chu i enfiah thei a, hei hi multiple myeloma chhinchhiahna dang a ni.
• X-ray: X-ray hmang hian multiple myeloma hian ruh a tichhe em tih hriat a ni.
• CT Scan (Computed Tomography - CT scan): Hei hi ruh chhiatna enfiahna test dang a ni.
• MRI scan (Magnetic Resonance Imaging - MRI): Hei hian magnet chak tak leh radio wave hmangin i ruh leh ruhro chipchiar taka thlalak a siam thin. Plasmacytomas ang chi thil zawng nan hman a ni a, chu chu tumor, plasma cell pangngai lo cluster-a lo awm a ni.
• PET scan (Positron Emission Tomography - PET scan): Hei hi plasmacytomas hmuhchhuahna atana hman thin scan chi dang a ni.
• Bone marrow biopsies: Doctor-te chuan ruhro sample tlemte an la a, plasma cell pangngai leh pangngai lo percentage an zirchiang a. DNA-a cancer thlen thei thil danglam a awm leh awm loh an enfiah thei bawk.

Engtin nge Multiple Myeloma stages te hi an hriat theih?

Doctor-te chuan multiple myeloma leh cancer dangte stage chu cancer hi eng chen nge a darh tawh tih leh eng chen nge a darh tawh tih an hriat chian tir thin. He stage hi enkawl dan tur ruahmanna siam nan hman a ni. Multiple myeloma stage hriat dan tur chu natna hi chi li zinga pakhatah then a ni a:

1. MGUS (Monoclonal Gammopathy of Undetermined Significance): Thisen test-ah hian M protein a tlem hle tih hmuhchhuah a ni. MGUS vei zinga 1% - 2% velin multiple myeloma an nei thei.

2. Solitary or isolated plasmacytomas: Hei hi plasma cell pangngai lo inzawmkhawm, pakhat chauh, hmun khata siam a ni.

3. SMM (Smoldering Multiple Myeloma): Hei hi cancer hmaa natna awm, Multiple Myeloma hmaa awm thin a ni. SMM vei te hian symptoms na lo tak tak an nei thei a, thisenah M protein tlem a awm a, ruhroah plasma cell a pung bawk.

4. Multiple Myeloma: He classification hian test-naah hian plasma cell pangngai lo cluster tam tak, thisen emaw zun emaw-ah M protein a sang a, ruhroah plasma cell pangngai lo percentage sang tak a awm tihna a ni. Heng mite hian thisen tlakchham (anemia), hypercalcemia, kal (kidney failure), leh ruh natna (osteolytic lesions) te an nei fo thin.

Tichuan, doctor-te chuan Revised International Staging System (R-ISS) an hmang ta a ni.Multiple myeloma stage hi R-ISS system an tih hmangin an chhut thin. He system hi thisen a albumin, beta-2 microglobulin, leh lactate dehydrogenase te level atanga siam a ni. Gene abnormalities bik test te pawh a ngaihtuah tel bawk.

Multiple Myeloma hi eng enkawlna nge ni?

Doctor-te chuan multiple myeloma hi i natna lan chhuah dan leh natna zau zawng a zirin an enkawl thin. Entirnan, MGUS vei te hian enkawl vat an ngai lo tlangpui. Mahse an doctor chuan an hriselna a enfiah fo ang. Tin, natna lanchhuahna a lo awm chuan hma la nghal turin enkawlna ruahmanna an siam thei bawk.

Multiple myeloma symptoms i neih chuan doctor-te chuan heng enkawlnate hi an hmang thei ang:

• Natna damdawi: Mi tam tak chuan ruh natna nasa tak an neih avangin hengte hi an mamawh a ni.
• Antibiotics: Immune system a chak lo deuh deuh chuan infection a awm nasa hle. I doctor chuan heng natna enkawlna atan hian antibiotics a pe thei ang.
• Steroids: Steroids hi a tam taka pek a nih chuan cancer cell te a that thei a, inflammation a tiziaawm thei bawk.
• Chemotherapy: Plasma cell pangngai lo awm zat tihtlem nan Chemotherapy hman a ni.
• Immunotherapy: He enkawlna hian i immune system a tichak a, cancer dotu cell tam zawk siam turin a tichak a ni.
• Radiation therapy: He enkawlna hian cancer cell a tichhia a, ruh tumor a ti tlem bawk.
• Stem cell transplant: Stem cell hi kan ruhro emaw thisen emawa awm, specialized cell chi khat a ni. Plasma cell thar, hrisel tak siam turin an pui thei a ni. Doctor te chuan autologous stem cell transplant an rawt tlangpui . Hei hian i taksa atanga stem cell hrisel tak tak hmanga stem cell chhia emaw, hrisel lo emaw thlak a huam a ni. A tlem berah chuan stem cell hrisel tak tak chu donor dang hnen atangin lak theih a ni. Hei hi allogenic stem cell transplant an ti a .

Multiple Myeloma natna hi eng chen nge i dam theih ang?

Mi thenkhat chu kum 10 emaw a aia rei emaw chhung chu multiple myeloma nen an khawsa thin. Cancer tam tak ang bawkin, a hmaa hriatchhuah leh enkawl hmasak hi a pawimawh ber a ni.Hei hian mite dam rei zawkna tura puitu chu a ni. Entirnan, plasmacytoma pakhat vei zinga 78% vel chu an hmuhchhuah atanga kum nga hnuah pawh an la dam a ni. Multiple myeloma vei te kum nga chhunga dam rei zawng zawng chu 40% atanga 82% inkar a ni. Heng chhiarpui te hi a hmaa kan sawi tawh R-ISS staging system atanga lak a ni.

Mahse, heng number te hi averages a ni tih hre reng ang che. I kum leh i hriselna zawng zawng an ngaihtuah lo a, chu chu mimal thil a ni. Multiple myeloma i neih chuan i doctor chuan i dinhmun chungchang a tha berin a hrilh thei che a ni.

Hei hi a thlen loh nan a veng thei ang em?

Ni lo, tunah hian multiple myeloma lo awm tur venna tur a awm lo. Researcher te chuan cancer hmaa stage SMM (Smoldering Multiple Myeloma) an tih chu active multiple myeloma a nih loh nan tihtawp dan tur an zawng mek a ni.

Engtin nge i in enkawl ang?

Multiple myeloma hian mi zawng zawng a nghawng dan a inang lo. Entirnan, MGUS emaw SMM vei te hian enkawl vat an mamawh lo mai thei. Mahse test neihpui turin an doctor an pan fo a ngai dawn a ni. Multiple myeloma atanga remission i nih chuan i doctor chuan i dinhmun a zirin check-up leh test neih hun tur a ruahman ang.

Multiple Myeloma vei i nih chuan i hriselna zawng zawng vawng reng turin thil engemaw zat i tih theih a awm a:

• Nitin chaw tha tak tak ei thin ang che. Multiple myeloma hian ei duh lohna a thlen thei. Chuvangin ni khatah chaw te te pali atanga panga ei tum ang che.
• Meizial zu mi i nih chuan bansan tum ang che.
• I taksa chu a mamawh chawlh hahdam pe la, muhil tha rawh.
• Infection lakah inveng rawh. I doctor hnenah hri kai laka inven dan tur zawt rawh.
• Exercise engemaw zat ti la, mahse doctor zawt hmasa phawt ang che. Eng ang exercise nge i tan a tha tih a hrilh ang che.
• I rilru hriselna pawh ngaihven rawh. Hetiang dinhmun kan hmachhawn hian lungngaihna, lungkhamna leh lungngaihna hi thil pangngai tak a ni. Mahse he lungngaihna emaw, lungkhamna emaw hian kar hnih aia rei a daih a nih chuan, emaw, nitin hnathawhna a tibuai a nih chuan, i doctor nen sawiho rawh.
• If you’re in remission , enkawlna a tawp tawh avangin i lawm mai thei. Mahse cancer chu a lo let leh ang tih pawh i hlau mai thei. I dinhmun leh hmalam pan zel tura i beisei turte chu i doctor nen sawiho rawh.

Multiple myeloma hi thisen cancer hmuh tur awm lo tak a ni. Dam theih ni lo mah se, doctor-te chuan a kaihhnawih natna, a lan chhuah dante chu an enkawl thei a, natna darh zel chu an thunun thei a ni. Mi thenkhat chu kum tam tak chhung chu he natna nen hian an khawsa thin. Midangte chu remission-ah an awm bawk. Amaherawhchu, cancer reh lo leh lo kir leh thei nen nun chu thil awlsam a ni lo. I dam chhung nitin enkawlna leh test hmanga nun tihna a ni. Doctor-te chuan heng harsatnate hi an hrethiam a ni. Multiple myeloma nena nun zir tura tanpuina i mamawh chuan i doctor zawt rawh. Service leh programme \angkai tak takte an hrilh thei che a ni.

In lama kan hruai duh ber chu

Okay, chuti a nih chuan, kan sawi tawh atanga i hriat reng tur pawimawh ber chu hengte hi a ni:

• Multiple Myeloma hi thisen cancer hmuh tur awm lo tak a ni a , plasma cell ah a lo awm thin .
• Dam vek theih ni lo mah se, enkawlna chuan natna lan chhuah dan a thunun thei a, dam rei zawng a ti rei thei a, nunphung a ti ṭha thei bawk .
• Ruh na, hahna nasa tak, emaw natna kai fo ang chi symptoms i neih chuan doctor pan nghal rawh.
• Diagnosis a hma poh leh enkawlna a hlawhtlin theihna a sang zawk.
• He natna nena kan nun hian mahni in enkawl tha a, doctor thurawn zawm a, rilru lama chak taka awm reng a pawimawh hle .

Lungngai suh, nangmah chauh i ni lo. Medical science a lo thang chho zel a, enkawlna thar a chhuak zel bawk. I doctor leh healthcare team te chuan tanpui turin an inpeih reng a ni.

` multiple myeloma, plasma cells, thisen cancer, ruhro, M protein, cancer symptoms, cancer enkawlna