MSA (Multiple System Atrophy) natna hi taksa system engemaw zat a nghawng thin tih i hria em?

Ngaihtuah teh, rang takin kal i harsat a, i balance i hloh a, i ṭhutna aṭanga i ding chuan i lu a buai a, i tlu bawk. Heng thilte hi a lo thleng nghal mai hian hlauhna nasa tak neih hi thil pangngai a ni. Hengte hi a chang chuan ngaihven vak lo mah ila, natna hmuh tur awm lo thenkhat chhinchhiahna hmasa ber an ni thei. Vawiin hian chutiang natna hlauhawm tak, mahse na tak tak, thluak lam natna pakhat chungchang kan sawi dawn a ni. Chu chu Multiple System Atrophy , keini doctor leh damlote’n a tawi zawngin (MSA) kan tih natna a ni. Hei hi thupui buaithlak deuh mahse, awlsam takin, in hriatthiam theih angin kan sawi dawn a ni.

A awlsam zawngin, he MSA hi eng nge ni?

MSA hi thluak lam natna hmuh tur awm lo tak a ni a, kan thluak hmun thenkhat chu zawi zawiin a chak lo va, a thi bawk. Hun a kal zel a, heng thluak hmun chhia te hian taksa theihna leh hnathawh te chu a bo zauh zauh a. Dik tak chuan hei hi thil lungchhiatthlak tak a ni a, a chhan chu he natna hi a tawpah chuan thihnaah a tawp thin.

Tun hma chuan doctor-te chuan he symptoms khawlkhawm hi hming pathumin an vuah thin. Anni chu:

• Shy-Drager natna a ni
• Olivopontocerebellar atrophy a awm fo thin
• Striatonigral tihchhiatna (striatonigral degeneration) a ni

Mahse a hnuah zirchiangtute chuan heng natna pathumte hian thil inang tam tak an nei tih an hrechhuak ta a ni. Chuvangin, an inzawm khawm vek a, "Multiple System Atrophy" (MSA) tiin an vuah ta a ni. "Multiple System" tih awmzia chu "system engemaw zat" tihna a ni. Chumi awmzia chu he natna hian kan taksa chhunga system engemaw zat a nghawng tihna a ni. A symptoms chu thluak peng engte nge a chhiat tih a innghat a ni. Chuvangin mi tin hian symptoms combination hrang hrang an nei thin.

A hnuah chuan natna hi classified lehzual a ni a, a bik takin a symptoms a lan dan a zirin a ni. Chumi ang chuan MSA hi chi hnih a awm a.

MSA vei theihna hlauhawm ber chu tute nge ni?

MSA hian puitling a vei tlangpui a, a bik takin kum 30 an tlin hnuah a natna lan chhuah dan hi kum 50 leh 59 inkar vel a ni tlangpui a, he natna hian tu pawh a nghawng thei a, mipa leh hmeichhia pawh thliar lovin.

Hei hi natna hmuh tur awm lo tak a ni. Statistics atanga a lan danin kum khatah mi 100,000-ah hri kai thar 0.6 atanga 0.7 chauh an awm. Hei hi kan khawtlang nunah natna tlanglawn tak a ni lo tihna a ni.

MSA natna hian engtin nge kan taksa a nghawng?

MSA hian thluak hmun hrang hrangah cell a tithi a. Symptoms chu thluak peng engte nge chhiat tih ah a innghat. Thluak peng lian ber berte chu:

• Basal Ganglia: Hengte hi thluak lai takah a awm a. Thluak hmun hrang hrang inzawmkhawmtu hub ang mai an ni. Hemi part hmang hian thluak peng hrang hrangte chu an inzawm khawm a, an thawk ho thin.
• Brainstem: Hei hi kan taksaa kan dam khawchhuahna atana pawimawh tak, automatic process te control na hmun a ni. Entirnan, thawk dan, lungphu leh thisen sang ang chi thil te. Heng thilte hi kan ngaihtuah ngai lovin a thleng nghal mai thin a ni lawm ni? Hei hi control center a ni.
• Cerebellum: Hei hi lu hnung lamah, a bul hnaihah a awm a. Hei hi kan thluaka kan taksa chetna inrualremtu leh kan balance vawng rengtu ber a ni. Chu bakah, tunah chuan zirchianna chuan he part hi kan rilru put hmang leh thutlukna siamnaah pawh a inrawlh tih hmuhchhuah a ni.

Chuvangin, thluak chhunga heng hmun hrang hrangte hi a chhiat chuan chu peng hrang hrangte thunun process zawng zawng chu a kal ta vek a ni. Entirnan, `(brainstem)` a chhiat chuan thisen sang ang chi automatic process-ah harsatna lian tak a awm thin.

MSA natna lan chhuah dan berte chu engte nge ni?

MSA-ah chuan symptom thenkhat chu chi hnih tan hian a awm tlangpui. Chu bâkah, chi hrang hrang tâna thil chi hrang hrang a awm bawk. A chi hnih a thil langsar ber chu autonomic dysfunction a ni . A awlsam zawngin kan taksaah hian automatic-a thil thlengte hian hna a thawk tha lo.

Autonomic Dysfunction natna lan chhuah dan

• Orthostatic Hypotension: Hei hi mi tam takin an tawn hmasak ber a ni. Thut emaw mu emaw atanga i ding nghal chuan i thisen sang chu a tlahniam nghal vek a ni . Hei hian luak a tichhe thei a, mit a ti fiah lo thei a, muhil pawh a thlen thei bawk.
• Zun leh bawlhhlawh control theih lohna: Zun insum theih lohna leh ek incontinence hi i beisei loh ber laiin a awm thei.
• Sexual dysfunction: Mipat hmeichhiatna hman lai hian erectile dysfunction ang chi harsatna, a bik takin mipaah ​​a awm thin.
• Mut lama harsatna: A bik takin, ``(REM) sleep behavior disorder'' tih dinhmun hi hmuh tur a awm. Hetah hian mumang i neih hian i mumang chhanna atan i taksa i ti che a, i au a, i taksa pengte i flail bawk.
• Thawmhnaw tlakchham (Anhidrosis): Taksa thawk hah theihna hi nasa takin a tlahniam a.
• Mit lama harsatna, hmui vawt, mut lama thawk hah, leh chaw ei kham te pawh a awm fo.

Rilru leh rilru lam mizia

MSA vei hmun thuma ṭhena hmun khat vel chuan an ngaihtuahna leh ngaihtuahna seng kawngah harsatna an tawk ṭhin. An rilru put hmang thunun harsa an ti bawk a, chu chuan rilru lam harsatna chi hrang hrang a thlen thei a ni.

• Hlauhthawnna
• Lungngaihna
• Tap emaw, nuihzat loh emaw
• Panic attack a awm thin
• Mahni intihhlum emaw, intihhlum emaw ngaihtuahna

Movement nena inzawm Symptoms te

Heng mizia te hi a hmaa kan sawi tawh MSA chi hnih a zirin a inang lo.

Eng thilin nge MSA hi a thlen?

MSA awm chhan dik tak hi hriat a la ni lo . Mahse, scientist-te chuan protein pakhat alpha-synuclein . He protein hi thluak hmun hrang hrangah a pangngai lo takin a awm khawm a, thluak cell te a tichhia niin an ngai. Mak tak maiin he protein tho hi Parkinson natna thlentu nia rinhlelh a ni bawk.

Kan taksa hnathawhna atan protein hi a pawimawh hle. Mahse, heng protein te hi hmun dik lovah, kawng dik lovah an inkhawm chuan cell te a tichhe thei a ni. Chu chu MSA-ah a thleng thin.

He alpha-synuclein protein hi thluaka a khawlkhawm chhan hi zirchianna neih mek a ni. Genetic mutations vang pawh a ni thei ang tih rinhlelh a ni. A bik takin MSA-C chi hi thlah khat atanga thlah dangah eng emaw chen a kai theih tih finfiahna a awm. Mahse, MSA-P type tan chuan chutiang genetic link chu hmuh a la ni lo.

Engtin nge MSA hi hmuhchhuah a nih?

Hei hi natna a harsatna ber a ni. 100% chiang taka MSA confirm theihna awmchhun a ni.mi thih hnua thluak tissue enfiah hi a ni. A chhan chu tun dinhmunah hian mi nung thluaka alpha-synuclein protein hi a awm em tih enfiahna technology a awm lo.

Amaherawhchu, damlo a dam chhung hian doctor-te chuan natna hi an ringhlel thei a ni. Anni hian natna lan chhuah dan te, damlo damdawi lam chanchin te, chhungkaw chanchin te, leh enkawlna thenkhat a chhan dan te ang chi thil an hmang thin. Vawi tam tak chu doctor-te chuan a tir lamah Parkinson natna hi an hmuchhuak thei a. Mahse, hun kal zelah symptom dang a lo awm chhoh zel angin, emaw, Parkinson damdawiin hna a thawh tawh loh chuan, diagnosis chu MSA-ah thlak a ngai mai thei.

MSA leh Parkinson natna inthlauhna pawimawh tak tak

Diagnostic test te pawh a awm

MSA direct-a hriat theihna test hi a tlem hle. A tam zawkah chuan test hrang hrang an nei a, chu chu condition dang tihbo nan leh MSA hi a chhan ni thei nia rinhlelhna thlawp turin evidence an la khawm thin.

• MRI (Magnetic Resonance Imaging) scan: Hei hian a chang chuan thluak hmun thenkhat a tichhia tih a lantir thei. A bik takin MSA-C-ah chuan thluak hmun khatah hian "hot cross bun" sign an tih pattern hmuh tur a awm a. Cross bun lum tak ang mai a ni. Mahse, he chhinchhiahna hi natna dangah pawh hmuh theih a nih avangin MSA hriat theihna chiang tak a ni lo.
• Genetic testing: Hei hian alpha-synuclein protein nena inzawm genetic mutations a awm leh awm loh a enfiah thei a ni.
• Skin biopsy: Research thar thenkhat chuan he test hian vun nerve tissue-ah alpha-synuclein a awm leh awm loh hriat theih nan a pui thei niin an sawi. Mahse, hei hi research phase-ah a la awm a ni.

I doctor chuan i dinhmun a zirin eng test nge a tul nia a hriat tih leh chuta tang chuan eng nge i beisei tih a hrilhfiah ang che.

MSA enkawl dan tur a awm em?

Vanduaithlak takin tunah hian MSA damdawi a la awm lo . Chuvangin, enkawlna tum ber chu natna lan chhuah dan thunun a, a rei thei ang bera nunphung tha tak vawn reng hi a ni.

Enkawlna pek dan tur chu damlo natna lan chhuah dan leh a nasat danah a innghat a ni. Entirnan, thisen sang damdawi hi orthostatic hypotension atan pek a ni a, muscle relaxants for stiffness, leh urinary control na atan damdawi dang pek a ni bawk. Tin, physiotherapy leh speech therapy ang chi thil hi a pawimawh hle bawk.

He natna vei hian eng ang hmalam hun nge a beisei theih ang?

MSA hi natna zual zel a ni. A tuar zinga a chanve vel chuan natna lan chhuah tirh atanga kum 5 chhungin kea kalna tur (cane emaw walker emaw ang chi) an mamawh ang. Kum 5 chhungin 60% velin wheelchair an mamawh dawn a ni. Kum 6 atanga kum 8 inkar ah chuan damlo tam zawk chu khumah an muhil thin.

Natna a lo zual zel chuan taksa hnathawh dan tur vawng nung turin damdawi lam kalphung hrang hrang a ngai a.

• Tracheostomy hi kan rilruah khur te tak te siam a, thawk harsatna awm thei tura pui turin tube dah a ni.
• Tube feeding chu damloin a ei theih loh laiin tube hmanga chaw pek hi a ni.
• Tubing emaw surgery dang hmanga zun leh bawlhhlawh control dan.

A tlangpuiin MSA vei damlo pakhatin a dam rei zawng chu kum 6 leh kum 10 inkar a ni. A na lo deuh thenkhatah chuan kum 15 thleng dam theih a ni. Amaherawhchu, natna hi a na hle a nih chuan dam rei zawng hi a tawi zawk thei hle.

Thihna hi natna avanga harsatna awm vang a ni ber. Entir nan:

• Pneumonia natna (Pneumonia) a ni.
• Urinary tract infection avanga sepsis (thisen rimchhia) a awm.
• Mut laiin thluak in thawk dan a thunun theih lohna avanga thihna rang tak.

Kan hmangaihte hi engtin nge kan enkawl ang?

MSA vei mi pakhat chu hun kal zelah a natna lan chhuah dan a zual zel a, a tawpah chuan mahni inrintawkna nei lovin an awm thei lo thei a ni. Mahni ngaihtuahna te, thusawi te, leh thu tlûkna siam thiamna te pawh an hloh thei bawk.

Chuvangin, damlo chu a hriatna a la awm lai hian i hmangaih tak takte nen hmalam hun chungchang sawipui a pawimawh hle . Thutlukna siam thei lo dinhmunah i ding a nih chuan, i damdawi lam enkawlna chungchangah eng thutlukna nge siam tur tih i sawi lawk theih a, dan anga document i buatsaih theih chuan mi zawng zawng tan a awlsam hle.

Engtikah nge doctor i hmuh ang?

MSA natna lan chhuah hmasak ber tam tak hi doctor nen in sawiho ngei ngei tur thil a ni.

• Mipat hmeichhiatna hmansualna.
• Ding chhuah ruala luak chhuak chhunzawm zel leh hriatna hloh.
• Mut harsatna, a bik takin sleep apnea.

I doctor-in Parkinson’s ang chi movement disorder i neih thu a hrilh che a nih chuan i symptoms-a inthlak danglamna awm apiang sawi chhuah a pawimawh. A bik takin Parkinson’s damdawi (levodopa) hian hna a thawk lo a nih chuan chu chu MSA i vei thei tih hriattirna lian tak a ni.

MSA hi natna khirh tak, thihna thlen thei a ni. Damdawi a awm lo tih hi a dik a ni. Mahse, a symptom tam tak chu enkawl theih a ni. Chu enkawlna hmang chuan damlo nunphung chu kum tam tak chhung chu level tha takah a awm thei a ni. Chu hun chu an hmangaih tak takte nena hlim taka hun hmanna leh nun hlim taka an hman theihna hun remchang hlu tak a ni.