I hriatna hloh leh luak chhuak i nei bawk em? Neurofibromatosis Type 2 (NF2) chungchang hi i zir dawn teh ang!

I hriatna a hloh nghal a, i lu a buai mai mai em ni? I beng bulah thawm i hre mai mai em ni? Hengte hi thil pangngaiah i ngai a, mahse a chang chuan heng thil hnung lamah hian kan hriat tam loh natna a awm thei a, mahse kan fimkhur tur a ni. Vawiin hian chutiang natna chungchang kan sawi a ni. He natna hi Neurofibromatosis Type 2, a tawi zawngin NF2 a ni.

A awlsam zawngin sawi ila, Neurofibromatosis Type 2 (NF2) hi eng nge ni?

NF2 hi genetic condition a ni a, kan nervous system a nghawng a ni. Kan taksaa cell thang chakna control tu gene inthlak danglamna avanga lo awm a ni. He genetic change hian taksain cell a siam tam lutuk a. Heng cell tam lutuk te hi an pungkhawm thei a, tumor an siam thei bawk.

Mahse lungngai suh, heng lumps tam zawk hi benign , cancer a ni lo tihna a ni. Heng lumps te hi a bulpui ber chu:

• Peripheral nerve hi kan taksa peng hrang hrang, ke leh ke leh ke peng hrang hranga inzar pharh nerve a ni.
• Kan luruh leh thluak inkar (meninges) inkar membrane.
• Spine a ni.
• Thluak leh beng chhung lam thlunzawmtu nerve te, hriatna leh taksa inthlauhna atana puitu te.

NF2 hi natna chi khat Neurofibromatosis an tih zingah a tel a ni. He natna pawl hian kan vun leh nervous system a nghawng ber a ni.

Khawtlang nunah he NF2 dinhmun hi engtiang chiahin nge a hluar?

Hei hi thil awm lo tak a ni. Statistics atanga a lan dan chuan NF2 hian khawvel puma nausen piang 33,000 zinga pakhat vel a nghawng a ni. Neurofibromatosis vei hmuhchhuah zawng zawng zinga 3% vel chu NF2 vei an ni.

NF2 hi eng symptoms nge ni?

NF2 natna lan chhuah dan hi mi hrang hrangah a inang lo thei. I taksaa tumor awmna hmun leh a lian ziaah a innghat a ni. Mi tam zawk chuan beng leh thluak inzawmkhawmtu nerve-a tumor awm vangin symptoms an nei hmasa thin.

Heng symptoms te hi chiang taka hrethiam turin i en ang u:

Naupan lai atanga kum 30 inkar inkarah hian symptoms hi a lang tan fo thin a, mahse he natna hian kum eng pawhah tu pawh a nghawng thei a ni. Puitlingah chuan beng leh thluak thluak thlunzawmtu nerve te hi a nghawng hmasa fo thin. Chuvang chuan hriatna lama harsatna lo lang hmasa ber a ni. Naupangah erawh chuan thluak emaw, ruhro emaw-ah tumor a lo awm fo thin. Naupan lai emaw, tleirawl lai emawa symptoms a lan chuan natna hi a na zawk tih a tilang thei a ni.

NF2 ah hian eng chi tumor nge lo awm?

NF2 ah hian tumor chi hrang hrang a lo awm thei a. Anni hi han thlir thuai teh ang u.

Engvangin nge NF2 hi a lo awm? Eng nge a chhan?

A chhan ber chu kan taksaa Neurofibromin 2 (NF2) an tih gene inthlak danglam vang a ni. He gene hian protein ‘merlin’ an tih siam nan a pui a ni. He protein hnathawh ber chu tumor lian zel tur tihtawp a ni. Chu chu tumor-suppressor a ni tihna a ni .

Chuvangin, he NF2 gene-ah hian chhiatna a awm chuan ‘Merlin’ protein hi a siam tha lo hle a ni. Tichuan kan taksaa cell ṭhenkhat chu thunun theih lohvin an inṭhen a, an pung a, an inzawm khawm a, tumor an siam a ni.

Hetiang dinhmun avang hian eng harsatna nge awm thei?

NF2 hi control a nih loh chuan complication thenkhat a awm thei. Chung zingah chuan:

• Hriatna hloh vek
• Mit hmuhna hloh
• Nerve chhiatna awm reng
• Thluak a tui awm zat (hydrocephalus) .

Heng tumor te hi cancer ni lo mahse, NF2 tumor thenkhat chu cancer a nih theihna chance a tlem hle a, a tlem hle. Chuvangin regular medical checkup neih hi a pawimawh hle a ni.

Engtin nge NF2 hi hmuhchhuah a nih?

Doctor i pan hunah uluk takin a enfiah hmasa ang che a, i natna lan chhuah dan leh i chhungte zingah he natna hi tu emaw chuan an vei tawh em tih te a zawt hmasa ang che. Tichuan, a natna hriat chian nan test eng emaw zat a ti thei ang:

• MRI (Magnetic Resonance Imaging) scan: Hei hian nervous system leh vunah tumor awmte chu chiang takin a hmu thei a.
• Hearing test: I hriatna level enfiah rawh.
• Mit enfiah: Mit (cataract) emaw, mit lama harsatna dang emaw a awm leh awm loh enfiah thin ang che.
• Genetic testing: NF2 gene-ah hian chhiatna a awm leh awm loh finfiah nan.

NF2 enkawl dan tur chu engte nge ni?

Hei hi damdawi a la awm lo. Mahse, lungngai suh, tunah chuan heng tumor te hi hriatchhuah, enkawl leh enkawl dan hmasawn tak tak a awm ta. I doctor chuan i tana tha ber tur enkawlna a thlang ang. Enkawl dan hi mi hrang hrangah a inang lo thei.

Enkawl dan tlangpui thenkhat chu hetiang hi a ni:

• Surgery: Surgery hmanga symptomatic tumor te lakchhuah. Surgery hmanga mittui tlakna (cataract) tihbo nan pawh hman a ni.
• Chemotherapy emaw Radiation Therapy: Heng enkawlnate hi tumor thenkhat lian tham tihziaawm nan an hmang thin. Chutiang radiation therapy hmanraw hmasawn tak pakhat chu Stereotactic radiotherapy hi a ni.
• Hriatna leh mit hmuhna hmanrua: Hriatna lama harsatna nei te chuan `Hearing aids`, `cochlear implants` emaw `auditory brainstem implants` ang chi hmanrua an hmang thei a ni. Mitmeng ang chi thilte hian mitdelna kawngah a pui thei a ni.
• Aids dang: Balance leh kea kal harsatna i neih chuan mobility devices i hmang thei ang.
• Damdawi: Natna ang chi symptoms control nan doctor chuan damdawi a pe thin.

Engtik hunah nge doctor ka hmuh ang?

A hnuaia symptoms pakhat emaw a aia tam emaw i neih chuan doctor pan ngei ngei tur a ni.

• Mit hmuh dan inthlak danglam.
• Hriatna a inthlak emaw, beng a ri emaw.
• Muscle chak lohna emaw, hmai tlahniam emaw.
• Skin bumps emaw spot thar emaw a awm.
• Lu na reng reng.
• Chhan awm lovin taksa peng hrang hrangah natna.
• Fit (seizures) neih.

Vawi tam tak chu hriatna emaw, mit hmuhna lama inthlak danglamna hi he natna chhinchhiahna hmasa ber a ni. Chuvangin, heng symptoms zinga pakhat tal i neih chuan, tihkhawtlai lohvin damdawi lam thurawn zawng la.