Nangmah emaw, i chhungte tu emaw chuan i doctor-in ‘Ruxolitinib’ tih damdawi a lo pe tawh pawh a ni mai thei. A hming hi a buaithlak deuhin a lang thei. Mahse, hlau suh. A pawimawh ber chu heng damdawi bikte hi kimchang taka hriat a, hman a ni. Chuvangin vawiinah hian he damdawi hi eng nge a nih, eng nge a tih, kan hman huna kan fimkhur a ngaih thute han sawi ila.
Ruxolitinib hi eng nge ni?
A awlsam zawngin sawi ila, Ruxolitinib hi kan taksa cell chhunga protein thenkhat target a, an hnathawh dan control thei damdawi a ni a, chu chu cell te thanna tur a titawp tihna a ni. Hei hi targeted therapy an ti a .
He damdawi hi natna pathum enkawlna atan hman a ni ber a:
- Myelofibrosis: Hei hi ruhroah fibrous tissue a lo awm khawm a, thisen cell hrisel siam chhuahna a tibuai a ni.
- Polycythemia Vera: Hetiang dinhmunah hian taksain a tul aia tam thisen sen (red blood cells) a siam chhuak thin.
- Graft-versus-host disease: Hei hi bone marrow transplant ang chi thil engemaw hnuah a lo awm a, chu chu transplanted cells te hian kan taksa ngei hi an rawn bei tan a ni.
I doctor chuan he damdawi hi natna dang atan pawh a rawt thei bawk.
Damdawi ei tan hmaa doctor hnena i hrilh tur thilte
He damdawi hi i tan hma hian hriselna lama harsatna i neih apiang i doctor hnenah hrilh hmasak a pawimawh hle . A hnuaia mi hi i neih chuan hrilh ngei ang che.
| Nihna | Hrilhfiahna |
|---|---|
| Lung natna leh thisen kalna kawng lama harsatna a awm | Tun hmaa heart attack emaw stroke emaw, thisen zam harsatna emaw, cholesterol level sang emaw i neih tawh chuan. |
| Infection awm thei te | Tuberculosis (TB), Hepatitis, emaw bacteria, viral, fungal infection dang emaw vei tawh emaw, tun hmaa emaw a awm tawh. |
| Kidney emaw liver emaw natna | Kidney natna i neih emaw, dialysis i neih emaw, liver natna i neih emaw chuan. |
| Thisen lama harsatna leh cancer | Thisen zat tlem, thisen var tlem, thisen sen hniam, platelet hniam, cancer dang i neih chuan. |
| Point dang pawh | Meizial zu mi, naupai tum, naupai, hnute pek tum i nih chuan i doctor hnenah hrilh rawh. Ruxolitinib emaw damdawi dang emaw ei tur dang emaw allergy i neih chuan doctor hnenah hrilh rawh. |
He damdawi hi engtin nge ka hman ang?
He damdawi hi tui glass khat nen ei tur a ni. Chaw ei rual leh ei loh pawhin ei theih a ni. Amaherawhchu, pum na i neih chuan chaw ei ruala ei a tha ber.
Pawimawh tak: He damdawi ei lai hian grapefruit tui in vek loh tur a ni , grapefruit tui hian he damdawi hnathawh dan a nghawng thei a ni.
Nitin i damdawi chu a hun ruala ei tum ang che. Dose chu doctor-in a tih ang chiah khan ei rawh. Side effect i neih chuan i doctor chuan a dose thlak emaw, damdawi ei tawh loh emaw a hrilh thei che a ni. Dose hi thlak ngai suh la, doctor thurawn tel lovin damdawi ei kha titawp ngai suh.
Damdawi dose khat i ei loh chuan engtin nge ni ang?
I hriatreng veleh missed dose kha ei nghal rawh. Mahse, i dose leh tur hun a lo thleng tawh a nih chuan missed dose kha skip la, a hnuaia dose chu a hun ruatah ei rawh. Eng thil vang pawhin double dose ei loh tur .
Damdawi ka ei tam lutuk chuan engtin nge ni ang?
Damdawi i ei tam lutuk nia i hriat chuan Colombo National Hospital-a National Poisons Information Center-ah call nghal rawh . A nih loh leh damdawi in hnai ber Emergency Treatment Unit (ETU)-ah kal rawh.
Ruxolitinib nena inzawm thei damdawi dang
I damdawi ei zawng zawng, prescription leh over-the-counter damdawi, hnam damdawi, vitamin, leh herbal products (St. John’s wort ang chi) te chu i doctor hnenah hrilh rawh. Damdawi thenkhat chu Ruxolitinib nen an inzawm thei.
A hnuaia tarlan te hi entirnan tlemte chauh a ni:
- HIV emaw AIDS emaw avanga antiviral damdawi ei thenkhat
- Fungal natna damdawi (e.g. fluconazole, ketoconazole) .
- Antibiotics thenkhat (e.g. clarithromycin, erythromycin) te hi a tha hle.
- Epilepsy/ seizure natna atana hman damdawi thenkhat (e.g. carbamazepine, phenytoin) .
- Rifampin (TB natna damdawi) .
- Herbal atanga siam St. John’s wort a ni
He list hi a kim lo va, chuvangin i ei tur zawng zawng hi doctor hnenah hrilh vek a pawimawh hle .
Damdawi ei huna fimkhur tur bikte chu engte nge ni?
He damdawi i ei lai hian i taksa a inthlak danglamna hi ngaihven a tha hle.
- Thisen test: I doctor chuan i thisen cell lian tham inthlak danglamna ang chi thilte enfiah turin thisen test a ti fo ang.
- Infection hlauhawmna: He damdawi hian taksain natna a do theihna a ti tlem thei a, chu chu immunity a ti tlem thei a ni. Chuvangin, khawsik, khawsik, ril na, khuh ang chi symptoms i neih chuan mahni invenna nei lo la, doctor hnenah hrilh zawk rawh. Damlo awmna hmuna kal chu a theih ang anga tihtlem.
- Thisen chhuah leh hliam: I taksaah sawifiah theih loha hliam i neih chuan, emaw, hliam tenau a\ang pawhin thisen chhuah a tawp lo a nih chuan doctor hnenah hriattir tur a ni.
- Cancer hlauhawmna: He damdawi ei thin thenkhat hian cancer chi dang, vun cancer ang chi an vei theihna chance a sang deuh thei. Chuvangin ni chhuahnaah i vun khuh la, sunscreen hmang la, hei hi i doctor nen pawh sawipui rawh.
- Thluak natna khirh tak: A tlem hle a, damlo thenkhat chuan thluak natna khirh tak an nei thei. Hmuh, tawng, ngaihtuahna, kal emaw, ding emaw harsatna i neih chuan emaw, buaina i neih chuan doctor hnenah hrilh nghal rawh.
- Nu naupai: He damdawi i ei lai leh damdawi i ei zawh hnu kar 2 chhung chu naute hnute pe suh.
Eng side effect nge ka neih theih ang?
Damdawi dang ang bawkin Ruxolitinib hian side effect a nei thei a ni. Ṭhenkhat chu serious tak an ni a, ṭhenkhat erawh chu an awm fo. Hengte hi fimkhur a pawimawh hle.
| Side effect a awm thei | Hrilhfiahna |
|---|---|
| Side effect na tak tak, doctor hnena hriattir nghal tur | |
| Allergy natna a awm thei | Vun vun rawng, hnim hring, hmai, hmui emaw lei emaw a hring. |
| Thisen chhuak | Chhung na, thawk harsa, na, hring, emaw ke lumna hriatna. |
| Lung natna | Thâwk harsa, rilru, kawr, hnungzang emaw, kut emaw a na emaw, a nghet lo emaw, hah lutuk. |
| Thai | Mit a inthlak danglam, buaina, tawng leh hriatthiam harsa, lu na nasa tak, hmai, kut emaw, ke emaw a rang lutuk emaw, chak lohna emaw a awm. |
| Thisen chhuah emaw, hliam emaw danglam tak | Sawifiah theih loh hliam, thisen chhuak tawp lo tur. |
| Side effects nasat loh tlangpui, mahse a awm reng chuan doctor hnenah hriattir tur a ni | |
| Natna tenau dangte | Diarrhea, lu na, muscle cramps, ke leh ke ruh natna. |
He list-ah hian side effect awm thei zawng zawng a tel lo. Thil danglam tak i tawn chuan doctor nen inbia ang che.
Take-Home Thuchah a ni
- Damdawi, vitamin leh herbal product i ei zawng zawng chu i doctor hnenah hrilh vek ang che.
- He damdawi hi i ei lai hian grapefruit tui in loh tur a ni.
- Infection chhinchhiahna i hmuh chuan khawsik leh khuh, emaw, thisen chhuah emaw, hliam emaw, a danglam bikna i hmuh chuan damdawi lam thurawn la nghal rawh.
- I rilru natna, thawk harsa, tawng harsa tih ang chi symptom na tak tak i neih chuan damdawi in Emergency Department (ETU) ah kal nghal rawh.
- Doctor thurawn tel lo chuan damdawi ei kha bansan ngai suh la, a dose pawh thlak ngai suh.
- He damdawi chungchangah hian ngaihtuahna i neih chuan i doctor hnenah sawipui hlau suh.
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