Cancer dona hi zinkawng awlsam a ni lo tih kan hre vek. He zin chhung hian i doctor chuan damdawi chi hrang hrang a pe thei che a ni. Sunitinib hi chutiang damdawi pakhat a ni a, cancer cells te chu a target a, an thanlenna a titawp a ni. Chuvangin, he damdawi hi i lo pe tawh a nih chuan, awlsam leh chiang taka hriat chu i enkawlna kawngah tanpuitu lian tak a ni ang. Hemi chungchang hi han sawi ila.
Sunitinib hi eng damdawi nge ni?
A awlsam zawngin sawi ila, Sunitinib hi damdawi a ni a, "targeted therapy" category-ah a tla a ni. Chumi awmzia chu he damdawi hian taksaa cell zawng zawng a nghawng mai ni lovin, cancer cells te tihpun leh darh zel tura puitu protein bikte a hriatchhuah a, a titawp zawk tihna a ni. Hei hi hmelma direct-a target ang a ni.
He damdawi hi cancer chi hrang hrang enkawlna atan hman a ni ber:
- GIST (Gastrointestinal Stromal Tumors): Hei hi kan chaw ei kawngah hian tumor chi khat bik a ni.
- Advanced Kidney Cancer: Kal cancer chu taksa peng dangah a darh tawh chuan.
- Pancreatic Neuroendocrine Tumors: Hei hi cancer chi khat bik a ni bawk a, pancreas-ah a awm thin.
Damdawi ei tan hmaa doctor hnena i hrilh tur thilte
Sunitinib i ei tan hmain i doctor hnenah i hriselna chanchin kimchang i hrilh hmasak phawt a pawimawh hle . Hei hi a chhan chu he damdawi hian damdawi lam dinhmun thenkhat nen a inzawm thei a ni. A hnuaia table hi en rawh. Heng zinga pakhat tal i neih chuan doctor hnenah hrilh ngei ang che.
| Situation i report tur a ni | Engvangin nge chu chu? (Doctor in a hriat tur chhan) . |
|---|---|
| Thisen chhuahna lama harsatna emaw, hliam awlsam tak emaw | He damdawi hian thisen chhuah theihna a tipung thei a ni. |
| Ha lama harsatna, ha lem i hman chuan | Ha enkawl dan tur ruahman lawk tur a ni a, damdawi ei hian hmui ruh a nghawng thei a ni. |
| Zunthlum | Thisen sugar level a nghawng thei a ni. |
| Surgery i neih thuai dawn a nih chuan | Hliam damna a nghawng avangin, operation hma leh operation zawhah damdawi hi tihtawp a ngai a ni. |
| Lung natna, thisen sang, thinlung rhythm disorder te | He damdawi hian thinlung hnathawh leh thisen sang a nghawng thei a ni. |
| Kidney (cancer ni lo) emaw, thin natna emaw | Heng taksa peng hrang hrangte hnathawh hian damdawi hnathawh dan a nghawng a ni. |
| Thyroid natna a ni | He damdawi hian thyroid hormone level a nghawng thei a ni. |
| Naupai i nih chuan, nau pai tum i nih chuan, nau hnute i pe a nih chuan | Hei hi a pawimawh hle mai! He damdawi hian pum chhunga naute tan harsatna nasa tak a thlen thei a ni. |
| Sunitinib emaw damdawi dang emaw ei tur dang emaw allergy nei | Allergy nei lo turin hei hi hriattir a pawimawh hle. |
He damdawi hi engtin nge i hman?
Hei hi hman dan tur chu a awlsam hle a, mahse a pawimawh hle.
- Damdawi chu tui glass khat nen a pumin ei rawh.
- Hei hi chaw ei hma emaw ei zawhah emaw i ei thei. Harsatna a awm dawn lo.
- A pawimawh ber chu Doctor-in damdawi a pek ang chiah chiah, a pek huna ei hi a ni.
- Engtikah mah, eng chhan vang pawhin, i doctor thurawn tel lovin damdawi ei kha bansan emaw, a dose thlak emaw ngai suh.
Damdawi dose i ei loh chuan engtin nge i tih ang?
Dose i miss a nih chuan i hriatreng veleh ei nghal rawh. Mahse, i dose leh tur thleng darkar 12 aia rei lo a nih chuan missed dose kha skip la, i dose leh tur chu a hun ruatah ei rawh. Vawi khatah vawi hnih ei ngai suh.
Damdawi ka ei tam lutuk chuan engtin nge ni ang?
I ngaihtuah aia tam damdawi i ei nia i ngaih chuan hlau suh la, damdawi in hnai ber Emergency Department (ETU) ah kal nghal rawh . A nih loh leh Colombo National Hospital a National Poisons Information Center ah biak theih a ni bawk .
Sunitinib nena inzawm thei thil dang
Hei pawh hi a pawimawh hle. Sunitinib i ei dawnin i damdawi ei zawng zawng (condition dang damdawi, vitamin, traditional medicine, herbal products te pawh tel) i doctor hnenah hrilh a pawimawh. Damdawi thenkhat chuan Sunitinib nen an inzawm a, a nghawng a tihziaawm thei a, a nghawng a tipung thei a, side effect hlauhawm tak tak a thlen thei bawk.
A bik takin a hnuaia mite hi fimkhur hle ang che:
- HIV emaw hepatitis emaw damdawi thenkhat
- Fungal natna damdawi (e.g. ketoconazole, itraconazole) .
- Antibiotics thenkhat (e.g. clarithromycin) .
- Seizure damdawi thenkhat (e.g. carbamazepine, phenytoin) .
- Herbal product St. John’s Wort a ni a, a hnah hi a hring vek a ni
- QT interval ti rei thei damdawi dang
- Grapefruit tui: Hei hi mi tam takin an hriat loh thil a ni. Grapefruit tui in hian Sunitinib hnathawh dan a nghawng thei a ni. Chuvangin he damdawi ei lai hian grapefruit leh grapefruit tui hi pumpelh vek tur a ni.
Damdawi ei huna fimkhur tur thil bik
Ha leh hmui hriselna
He damdawi hian a chang chuan hmui ruh (Osteonecrosis of the jaw) a tichhe thei a ni. Chuvang chuan damdawi ei tan hmain dentist pan hmasa phawt a tha ber a, ha lam harsatna eng pawh chinfel a tha. Tin, i ha enkawltu hnenah he damdawi hi i ei tih hrilh bawk ang che. Damdawi ei lai hian ha surgery lian tham tih loh hi a finthlak hle.
Surgery leh hliam damna
Sunitinib hian hliam damna a tikhawtlai thei a ni. Surgery i neih dawn chuan i oncologist hnenah hrilh rawh. Damdawi hi zai hma kar 3-ah chawlhsan a, hliam a dam tha hnuah (zai atanga kar 2 tal) ei tan leh a tha tlangpui.
Naupai, nau neih leh hnute pek
Hei hi a pawimawh hle mai!Hmeichhia i nih chuan he damdawi i ei lai leh damdawi i ei zawh hnu kar 4 tal naupai kim loh tur a ni. Mipa i nih chuan damdawi ei lai leh damdawi i chawlhsan hnu kar 7 tal naupai loh tur a ni.
He damdawi hian nausen piang lai tan harsatna nasa tak a thlen thei a ni. Chuvangin he hun chhung hian nau pai venna hmanraw rintlak tak hman a pawimawh hle. Tin, he damdawi ei lai leh ei zawh hnu kar 4 chhung chu nau hnute pek loh tur a ni.
Side effect awm thei te chu engte nge ni?
Damdawi dang ang bawkin Sunitinib hian side effect a nei thei a ni. Mahse, mi zawng zawngin an hmu vek lo. A pawimawh ber chu hengte hi hriat chian a, harsatna i neih chuan doctor hriattir nghal tur a ni.
| Side effects awm thei chu i doctor emaw damdawi inah report nghal tur a ni | |
|---|---|
| Allergy natna a awm thei | Skin rash, itching, hmai, hmui, lei hring |
| Thâwk harsa, rilru na | Thinlung emaw, lung emaw a nghawng thei a ni. |
| Pum natna nasa tak, thisen chhuah emaw, hliam emaw, a danglam bik | Internal bleeding chhinchhiahna a ni thei bawk. |
| Ke, ke ruh hring, taksa rihna sang nghal | Lung lam emaw, kal (kidney) lama harsatna a awm thei. |
| Jaw na (a bik takin ha lakchhuah hnuah) . | Jawbone-a nghawng a nei thei bawk. |
| Vun a sen, a hring, leh a hring chhuak | Skin reaction na tak a awm tih chhinchhiahna. |
| Thisen sang, lu na, seizures | Nervous system emaw thisen sang emaw a nghawng dan. |
| A awm reng emaw, a buaithlak emaw chuan doctor hnenah hrilh rawh. | |
| Kawthalo | Flatulence a awm. |
| Nausea leh luak chhuak | Nausea leh luak chhuak. |
| Kawngkhar natna | Kawng chhunga hliam. |
| Vun a inthlak danglam thin | Vun sen, a vawt, a chhe, leh kutphah leh kephah vun na. |
| Sam rawng inthlak danglam | Sam rawng ti engtu. |
| Chau | Thil danglam tak a chau tih hriatna. |
| Ei duhna hloh leh ei duhna inthlak danglamna | Ei duhna a tlahniam a, ei tur thlum a danglam bawk. |
Take-Home Thuchah a ni
- Sunitinib hi damdawi bik a ni a, cancer cells te a target a ni.
- I doctor thupek ang chiah kha zawm rawh. Damdawi ei kha bansan ngai suh la, nangmah chauhin a dose pawh thlak ngai suh.
- Damdawi dang zawng zawng, herbal products leh grapefruit tui i ei zawng zawngte chu i doctor hnenah hrilh rawh.
- Damdawi ei lai leh doctor-in a tih chhung zawng chu naupai leh nau hnute pek loh vek tur a ni. Naupai venna rintlak hman a pawimawh hle.
- Thâwk harsa, thisen chhuak danglam, taksa hring ang chi side effect na tak tak i neih chuan i doctor emaw, damdawi in hnai ber Emergency Department (ETU) emaw pan nghal rawh.
- Zawhna emaw, ngaihtuahna emaw i neih chuan i doctor nen sawiho rawh. I tanpui turin an inpeih reng a ni.
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