Tricyclic antidepressant hi engte nge ni? Heng damdawi te hi i zir chiang ang u!

Doctor-in lungngaihna emaw, natna dang emaw atân damdawi hlui tak a lo pe tawh che em? Tricyclic antidepressant (TCA) zinga mi a ni mai thei. A hming hi a hlauhawm deuhin a lang thei a, mahse hengte hi damdawi tangkai tak tak, natna tam tak atana hman thin an la ni tho. Chuvangin vawiin hian heng TCA damdawi te hi awlsam tak, hriatthiam awlsam takin i sawi dawn nia.

A awlsam zawngin, heng tricyclic antidepressant (TCA) te hi engte nge ni?

Tricyclic antidepressants, a tawi zawngin TCAs hi rilru lam natna major depressive disorder tia koh chhinchhiahna control-na atana puitu damdawi chi khat a ni. Mahse, tunlai doctor-te chuan heng damdawi te hi depression chauh ni lo, natna dang atan an pe thin.

Heng TCA te hi depression enkawlna atana damdawi chi hrang hrang hmuhchhuah hmasak ber zinga mi an ni. Chuvangin "first-generation" antidepressant kan ti a ni. Mahse tunah chuan depression enkawlna atana damdawi thar zawk, him zawk (SSRI ang chi) a awm tawh avangin doctor-te chuan heng TCA te hi depression damdawi atan first-line drug atan an pe tlem ta hle a ni.

Heng damdawi te hi an chemical structure avang hian "tricyclics" an ti a. Ring pathum an nei a. Chu chu a hming awmzia chu a ni a, ngaihtuah tur a awm lo.

Eng damdawi chi nge TCA group-a tel?

Hengte hi Sri Lanka leh khawvel hmun hrang hranga TCA damdawi hman ber ṭhenkhat an ni a, an brand hmingte nen. I doctor-in damdawi a pek chu heng zinga mi a ni em tih en rawh.

Tin, TCA damdawi Clomipramine (Anafranil®) hi obsessive-compulsive disorder (OCD) an tih natna enkawlna atan bik hman a ni bawk.

TCA damdawi hi eng condition atan nge hman a nih?

Heng damdawi te hi a bul berah chuan depression enkawlna atana pawm a ni. Mahse ka sawi tawh ang khan tunlai hian doctor-te hian depression atan an pe hmasa ngai lo. Damdawi thar dang (SSRI ang chi) te hian hna a thawk lo a nih chauhvin TCA hi tan theih a ni mai thei. A chhan chu mi thenkhat tan chuan heng damdawi hlui zawkte hian damdawi thar zawk aiin hna a thawk tha zawk chang a awm thin.

Mahse, tunah chuan TCA hi an pawmpui tawh loh natna dang enkawlna atan an lar ber a ni. Hei hi "off-label" hmanna kan ti a. Chu chu, chutiang dinhmun atan chuan damdawi chu Food and Drug Administration-in a pawmpui lo nachungin, damdawi lam zirchianna chuan chu natna atan chuan damdawi chu a tangkai hle tih a tarlang a ni.

TCA hman dan "off-label" thenkhat chu hetiang hi a ni:

• Migraines ven nan: Migraine vei fo thin tan chuan he damdawi hian a lo awm dan control nan a pui thin.
• Mut theih lohna: TCA thenkhat chu a tlem berah pek a nih chuan mut a tha thei hle.
• Anxiety disorders: Hengte hi lungkhamna chi hrang hrang control nan pawh hman a ni.
• Chronic pain: Hei hi tunlai TCA hmanna ber pakhat a ni. A bik takin neuropathic pain tan an tangkai hle . Entir nan:
• Diabetes kaihhnawih neuropathy
• Postherpetic neuralgia (chickenpox hnua natna lo awm) .
• Fibromyalgia natna a awm
• Bedwetting: He damdawi hi a chang chuan naupangte zan lama zun chhuah dan tur control nan a tlem berah pek thin a ni.

Damdawi thar (SSRI) leh heng damdawi hlui (TCA) te hi eng nge an danglamna?

An pahnih hian depression damdawi chi hrang hrang an ni. Mahse, danglamna pawimawh tak tak a awm. Hei hi a hnuaia table en hian awlsam takin i hrethiam thei ang.

He TCA damdawi hian taksa chhungah engtin nge hna a thawh?

Hei hi hriatthiam a awlsam hle. Kan thluaka nerve cell-te hian chemical neurotransmitter an tih hmangin thuchah an thawn a. Postmen te ang bawkin. Heng neurotransmitter pahnih hi kan mood control nan an pawimawh hle. Anni chu norepinephrine leh serotonin te an ni .

Depression ang chi dinhmunah chuan thluaka heng chemicals awm zat hi a tlahniam thin. TCA damdawi hian thluaka norepinephrine leh serotonin level tihsanin hna a thawk a ni. Hei hian nerve cell te inbiakpawhna tha zawk a siam a, mood a ti tha bawk.

Zirchiangtute chuan heng damdawi te hian natna a tihziaawm dan an hmuchhuak bawk. Heng damdawi te hian kan spinal cord kaltlangin thluak thlenga natna signal kal lo turin a block a, chu chuan kan natna hriatna a ti tlem a ni an ti.

Engtin nge damdawi hi ka ei ang a, a side effects te chu engte nge ni?

TCA hi tablet emaw capsule emaw angin a awm tlangpui. I doctor-in a dose dik tak ei a pawimawh hle .

Side effect awm fo thin

Damdawi zawng zawng ang bawkin he damdawi hian side effect a nei a. Mahse, mi zawng zawngin an hmu vek lo. Mi thenkhat chuan pakhat emaw pahnih emaw an dawng thei a, thenkhat erawh chuan an tawng lo mai thei.

Heng side effects te hian a tibuai che a nih chuan damdawi ei khap lovin doctor nen inbia ang che. Dose thlak danglam emaw, hmanraw dang hmanga enkawl theih an ni mai thei.

TCA damdawi chungchangah hian tute nge fimkhur bik tur?

Doctor ten he damdawi hi mi thenkhat hnena an pek hian an fimkhur hle thin. Heng natna te hi i neih chuan damdawi i ei tan hmain i doctor hnenah i hrilh ngei ang .

• Lung natna i neih chuan: TCA damdawi hian thinlung natna thenkhat a tichhe thei a, chuvangin i doctor chuan damdawi i ei tan hmain i thinlung hnathawh dan enfiah turin electrocardiogram (EKG) a ti thei ang.
• Epilepsy i neih chuan: He damdawi hian seizures i neih theihna a tipung deuh thei.
• Naupai emaw, naupai tum emaw i nih chuan: TCA damdawi hi naupai lai hian a him vak lo. Zirna thenkhatah chuan nausen (fetus) a nghawng thei tih hmuhchhuah a ni. Chuvangin he thu hi i doctor nen inbia ngei ang che.

Vaukhânna pawimawh tak a ni

Thil engemaw takah chuan naupang kum 25 hnuai lam, naupang tê tê, leh puitling tleirawlte chuan he damdawi hi an hman ṭan tirh hian mahni intihhlum duhna emaw, nungchang emaw a pung thei a, a bîk takin kar hmasa lamah chuan.

TCA damdawi hi overdose theih a ni em?

Ni e, i ti thei. Dik tak chuan antidepressant chi hrang hrang an pek zingah hian TCA hi damdawi hman tam ber pawl an ni. Chuvangin i doctor-in a dose aia tam i ei ngai lo tur a ni.

Overdose hi tihsual vang emaw, hriat loh vang emaw, tumruh vang emaw pawh a ni thei. Chuvangin i damdawi chu naupang leh ran vulhte hmuh theih lohna hmunah him takin dah fo ang che.

Overdose avanga natna lan chhuah dan

• Heartbeat dik lo (rhythm inthlak danglam) .
• Thisen sang a tlahniam lutuk
• Mutthilh nasat lutuk
• Seizures a awm thin
• Tremors a awm
• Rilru tibuai
• Coma ah a awm

TCA overdose hi medical emergency a ni a . Enkawl vat loh chuan thihna thlen thei a ni. Hetiang thil hi nangmah emaw, midang emaw chunga thleng nia rinhlelhna i neih chuan damdawi in hnai ber Emergency Department (ETU)-ah pan nghal rawh. A tul chuan Colombo National Hospital-a National Poisons Information Center- ah pawh thurawn dil theih a ni.

Doctor nen engtikah nge kan inbia ang

TCA damdawi i hman chuan doctor nen inbiak reng a pawimawh. A hnuaia natna te hi i neih chuan i doctor nen inbiakna neihpui ngei ang che:

• Side effects-in a tibuai nasa che a nih chuan: "Hei hi tuar theih loh khawpa tam a ni" tih i hriat chuan doctor hnenah hrilh rawh.
• I natna lan chhuah dan a ṭhat loh emaw, a zual emaw chuan: Kar 4 vel hnuah pawh a ṭhat loh chuan emaw, a natna lan chhuah dan chu a na zual ang tih a hriat chuan doctor hnenah hrilh rawh.
• Damdawi chawlhsan i ngaihtuah a nih chuan: He damdawi hi ei nghal vat ngai suh. Chutianga tih chuan withdrawal symptoms a awm thei. I chawlhsan a nih chuan i doctor-in a tih angin ti la, zawi zawiin a ei tur chu tihtlem rawh.

He damdawi hi hlui tawh mahse, a hman dik chuan a tangkai hle . Chuvangin, he damdawi chungchangah hian zawhna, hlauhna, rinhlelhna i neih chuan i doctor hnenah zawt la. A inpeih reng a, a puih duh che a ni.