Ka whakaputahia e tō tinana te insulin? Kia kitea tātou mā te whakamātautau C-peptide!

I mōhio koe he whakamātautau kei reira hei whakaatu mai i ngā kōrero nui mō te kaha o te tinana ki te whakaputa i tētahi homoni e kiia nei ko te insulin? Ko te whakamātautau C-peptide tēnei. Kāore pea koe i rongo i tēnei whakamātautau i mua. Engari he mea tino nui pea tēnei mō te tangata he mate huka tōna, he tangata rānei e whakapae ana he mate huka tōna. Me kōrero tātou mō te whakamātautau C-peptide i tēnei rā, āe?

He aha te C-peptide? He aha te hiranga ki a tātou?

He whakarāpopototanga noa iho, he mea iti te C-peptide e hangaia ana e tō tātou pancreas, te okana e kiia nei e tātou ko te "Pancreas" i te reo Pākehā, ina hangaia e ia te homoni insulin. He rite ki tētahi hua iti e puta mai ana i tētahi wheketere ina hangaia he hua matua. Nō reira, ka hangaia te C-peptide me te insulin i te nui ōrite e tō tātou pancreas.

Tērā pea koe e pātai ana, "He aha te insulin?" He homoni tino nui te insulin e whakahaere ana i te taumata o te huka, te hukahuka rānei, i roto i ō tātou toto. Ko te insulin te mea e āwhina ana i ngā pūtau o tō tātou tinana ki te whakamahi i te hukahuka e riro mai ana i a tātou ina kai tātou hei pūngao.

Titiro mai, kāore e taea e te hunga mate huka momo 1 te hanga i te insulin. Nō reira, me werowero te insulin ki waho. Engari, ka hangaia te insulin e te hunga mate huka momo 2 , engari kāore i te rawaka te nui, kāore rānei ngā pūtau o te tinana e aro tika ki taua insulin (e kiia ana hoki tēnei ko te "ātete insulin"). I ētahi wā, ka heke te hanga insulin o te hunga mate huka momo 2 i roto i te wā, ā, me tango te insulin ki waho.

Koinei te wā e hiranga ai te whakamātautau C-peptide. Nā te mea, ahakoa ka tangohia te insulin mai i waho e te tangata, kāore te C-peptide e haere tahi mai me taua insulin. Ka puta noa te C-peptide ina puta te insulin i roto i te tinana. Nō reira, mā tēnei whakamātautau, ka taea e ā mātou tākuta te kite i te nui o te insulin e puta ana i roto i tō ake tinana, i roto i tō ake repeure. Arā, ka taea te wehewehe i waenga i te insulin e puta ana i te tinana (insulin taketake) me te insulin e tangohia ana hei rongoā (insulin o waho).

Ka kiia hoki tēnei whakamātautau:

• Te hono i te peptide insulin
• Peptide-C insulin
• Proinsulin C-peptide

He aha te hononga o ngā taumata C-peptide ki te mate huka?

Kotahi te mea hei maumahara , kāore e taea e te whakamātautau C-peptide anake te kī mēnā he mate huka tō te tangata. Ko tāna anake e kī ana mēnā ka taea e tō repe taiaki te hanga i tana ake insulin, me te nui rānei.

Hei tino mōhio mēnā he mate huka tōu, ka tono te tākuta kia whakamātauria koe i te huka toto, i te whakamātautau A1c rānei, e ine ana i te taumata huka toto toharite mō ngā marama e toru kua hipa.

Nā, he aha ngā tākuta i tūtohu ai i tēnei whakamātautau C-peptide?

He maha ngā take e taunaki ai tō tākuta i tētahi whakamātautau C-peptide. Me titiro tātou ki ēnei:

• Whakarōpūtia te momo mate huka kei a koe: arā, whakatauhia mēnā he momo 1, he momo 2 rānei (ka mahia tēnei me ētahi atu whakamātautau).
• Me whakarite kei te tika te mahi a tō maimoatanga mate huka.
• Whakatauhia mēnā he nui te insulin e whakaputaina ana e tō tinana, mēnā rānei me werohanga insulin, me whakamahi rānei i te papu insulin.
• Kimihia ngā pūtake o te huka toto iti: Ka kiia tēnei ko te hypoglycemia.
• Kia mārama ki te rerekētanga i waenga i te insulin e hangaia ana i roto i te tinana me te insulin e werohia ana i waho.
• He tino onge, ka taea hoki e tēnei te whakarato i ētahi kōrero mō te mate pukupuku repeure.

Ko wai te kaimahi i tēnei whakamātautau C-peptide? Me pēhea te mahi?

I te nuinga o te wā, ka tūtohu tō kaiwhakarato tiaki tuatahi, tō tākuta endocrinologist rānei i tētahi whakamātautau C-peptide. He maha ngā wā ka mahia tēnei whakamātautau e te nēhi, e te tohunga taiwhanga rānei.

Ko te tikanga, ka inehia te C-peptide mā te tango tauira toto . I te tari tākuta, i te whare hauora, i te taiwhanga rānei, ka werohia e te nēhi he ngira angiangi ki roto i te uaua i tō ringa, ka kohia he toto iti ki roto i te ngongo. Tērā pea ka pāngia koe e te mamae iti ina werohia te ngira, engari kāore i te tino kino.

I ētahi wā ka taea te mahi i tēnei whakamātautau mā te whakamahi i tētahi tauira mimi . Engari ki te mahi koe i tēnā, me kohi e koe tō mimi katoa i roto i te wā 24-hāora. Mena koinei te āhua, ka hoatu e tō tākuta he ipu mōna, ā, ka hoatu hoki he tohutohu ki a koe mō te kohi me te whakahoki mai. Me pupuri pea e koe te ipu ki tētahi wāhi matao, pērā i te pouaka whakamātao. Engari kāore ngā tākuta e mahi tonu i tēnei whakamātautau mimi.

Me nohopuku ahau i mua i tēnei whakamātautau C-peptide?

Ae, ki te mea kei te whakamātautau toto koe, ka tonoa pea koe kia nohopuku mō te 8 ki te 12 hāora (he pai te wai anake) . Ka kiia tēnei ko te "Nohopuku". Heoi, i ētahi wā, ka hiahia pea tō tākuta ki te tirotiro i ō taumata C-peptide i muri i tō kai i tētahi mea, ā, ka whakaohokia tō repe taiaki. He maha ngā wā, ka tirohia hoki te taumata huka toto me ngā taumata C-peptide.

Waihoki, ka tono pea tō tākuta kia mutu te tango i ētahi rongoā mō te wā poto. Nō reira, he mea pai kia pātai atu ki tō tākuta he aha ngā mea e tika ana kia mahia e koe i mua i te whakamātautau.

He mōrearea kei roto i tēnei whakamātautau?

Ina hoki, he iti noa iho te mōrearea o ngā whakamātautau toto. Kāore he mōrearea e mōhiotia ana i roto i ngā whakamātautau mimi. Nō reira , kāore he take e mataku ai.

Kia pehea te roa ka puta mai ngā hua o te whakamātautau C-peptide?

Ko ngā hua o tēnei whakamātautau, arā, te pūrongo, ka roa pea mai i te kotahi ki te rima ngā rā ki te tae mai. Ka rerekē pea tēnei i runga i te tākuta me te taiwhanga.

He aha te uara noa o te whakamātautau C-peptide?

Ko te awhe hauora mō te whakamātautau C-peptide e kiia ana ko te 0.5 ng/mL ki te 2.0 ng/mL (0.17 ki te 0.83 nmol/L rānei) . Heoi, kia maumahara ka rerekē pea ēnei uara i ia taiwhanga, nō reira he mea nui kia whakatauritehia ō hua ki te awhe noa i runga i tō pūrongo.

He aha te tikanga o ngā hua o te whakamātautau C-peptide?

Āe, kia kite tātou i ngā kōrero a ngā uara o tēnei pūrongo whakamātautau.

Mena he iti te taumata C-peptide (C-peptide iti)

Mena kei te iti te taumata o te C-peptide i roto i te toto, tera pea etahi take:

• Ki te iti te taumata o te huka i roto i tō toto, ā, kāore anō koe kia kai i ngā wā tata nei, he mea noa pea te iti o te C-peptide.
• Heoi anō, tera pea he tohu anō kāore tō tinana e whakaputa ana i te nui o te insulin .
• Ki te werohia rānei te insulin ki waho, ka heke pea te C-peptide (nā te mea kāore te C-peptide e haere tahi mai me te insulin e tukuna ana ki waho).
• Ka hono pea tēnei āhuatanga ki ēnei āhuatanga hauora, inā koa mēnā he teitei te taumata o te huka toto:
• Mate huka momo 1 : Nā te mea kāore te repeure o ēnei tāngata e whakaputa i te insulin.
• Mate huka momo 2 : Ka puta tēnei ina kore e taea e te repeure te whakaputa i te insulin.

Ko tētahi atu mea e taea te kī mō te iti o ngā taumata C-peptide ko te kore e tino whai hua te maimoatanga mō te mate huka .

Tērā atu anō ngā āhuatanga e heke ai ngā taumata C-peptide i te hekenga o ngā taumata huka toto:

• Te mate a Addison : He āhuatanga tēnei e kore ai e nui ngā homoni cortisol me te aldosterone e hangaia e ō repe adrenal. Ko te tikanga ka iti te huka toto.
• Mate ate .
• Te hoatu i te insulin mai i waho (werohanga/manawa) `(Insulin o waho)` .

Ngā taumata C-peptide teitei

Nā, kia tirohia tātou he aha ka puta mēnā ka whakaatuhia e te pūrongo he teitei ake tō taumata C-peptide i te mea noa. Tērā pea he nui rawa te insulin e hangaia ana e tō tinana . Anei ētahi o ngā āhuatanga ka puta ai tēnei:

• Te mate a CushingKoinei te wā ka nui rawa te homoni cortisol e whakaputaina ana e tō tinana.
• Te ātete ki te insulin : Ahakoa kei roto i te tinana te insulin, kāore ngā pūtau e aro tika ki taua insulin. Nō reira, ka nui ake te insulin e hangaia ana e te tinana.
• Te iti o te pāhare pāporo i roto i te toto (Hypokalemia) .
• Mate huka momo 2 : Ka pā tēnei, inā koa i ngā wāhanga tōmua, ina ngana te tinana ki te hanga i te nui ake o te insulin.
• He pukupuku repeure : Hei tauira, he insulinoma.
• Te ngoikore o te whatukuhu : Nā te mea ka tangohia te C-peptide mai i te tinana mā roto i ngā whatukuhu, ka piki ake ngā taumata C-peptide i roto i te toto ina kore e mahi tika ngā whatukuhu.

He mea nui: Ki te kore e whakaatuhia he C-peptide i te whakamātautau C-peptide, ko te tikanga me tango e koe te insulin i waho. Ka taea tēnei mā te werohanga insulin, mā te papu insulin rānei.

Karere Tangohia ki te Kāinga

Āe, ko tāku tumanako kua mārama ake koe ki te whakamātautau C-peptide i kōrerohia e tātou.

• Ko te C-peptide he ine i te nui o te insulin e hangaia ana e tō tātou tinana.
• Mā tēnei ka āwhina i te wehewehe i waenga i te mate huka momo 1 me te mate huka momo 2 .
• Ka whakamahia hoki hei tirotiro i te whai huatanga o ngā maimoatanga mate huka .
• Ka āwhina hoki tēnei ki te tautuhi i ētahi atu mate hauora .

Mena kua tonoa koe e tō tākuta kia mahi i tēnei whakamātautau C-peptide, kia tino pātai atu koe ki a ia he aha te mea tika kia mahia, me te aha kāore e tika kia mahia i mua i te mahi. Kaua e wehi i tetahi mea, he whakamātautau māmā noa iho tēnei e whakarato ana i ngā mōhiotanga whai hua mō tō hauora. Ko te mea nui ko te kōrero ki tō tākuta mō ngā mea katoa, me te pātai atu i ō pātai.

` C-peptide, mate huka, insulin, repe taiaki, whakamātautau toto, homoni, hauora