Kei te matewai tonu koe, ā, kei te mimi pinepine? Tērā pea nā te Arginine Vasopressin Disorders (Diabetes Insipidus) tēnei?

Whakaarohia ahakoa te nui o te wai e inuhia ana e koe, e ahua matewai ana koe. I taua wā anō, me haere tonu koe ki te wharepaku. Kāore e taea e koe te moe pai i te pō, ā, me ara ake koe i ngā wā maha. Kāore ianei tēnei i te āhua whakararuraru? Ahakoa he tokomaha te hunga e whakaaro ana he mea noa tēnei, i ētahi wā he tohu pea nō tētahi atu raruraru i roto i tō tātou tinana. I tēnei rā ka kōrero tātou mō tētahi mate onge, engari ka taea te rongoā. Koia te Arginine Vasopressin Disorders, ko te Diabetes Insipidus rānei e mōhiotia ana e te tokomaha i tōna ingoa tawhito.

Ki te kī ngāwari, he aha ngā Mate Arginine Vasopressin?

Ahakoa he ahua uaua te ingoa, he tino māmā ki te mārama ki te mea e tupu ana. He māmā noa iho, he āhuatanga tēnei e kore ai e taea e te tinana te pupuri i te nui o te wai e hiahiatia ana. Nō reira, ka tukuna atu hoki te nui o te wai e hiahiatia ana i roto i te mimi.

Ko te take matua mō tēnei he homoni kei roto i tō tātou tinana. Ko te ingoa ko te Arginine Vasopressin (AVP) . E kīia ana hoki e ētahi tākuta ko te Antidiuretic Hormone (ADH) . He rite tēnei homoni AVP ki tētahi kaiwhakahaere e tuku tohutohu ana ki ō tātou whatukuhu. Koinei te mea e kī ana ki ngā whatukuhu, "Āe, me wai te tinana ināianei, nō reira penapenahia he wai, ā, whakaitihia te nui o te wai e tukuna ana hei mimi."

I roto i tēnei mate, e rua ngā huarahi matua e taea ai te whakakore i tēnei tukanga:

1. Te Kore AVP (AVP-D): Koinei te wā kāore e taea e tō tātou roro te whakaputa i te homoni AVP i te nui e hiahiatia ana. Ko te tikanga o tēnei, kāore he tangata hei tohutohu i ngā whatukuhu.

2. Te Ātete AVP (AVP-R): I roto i tēnei, ahakoa te nui o te homoni AVP e whakaputaina ana e te roro, kāore ngā whatukuhu e whakaae ki te tohutohu. Pērā i te kaiwhakahaere e tuku tohutohu ana engari kāore ngā kaimahi e aro.

Ahakoa pēhea, he rite tonu te mutunga: ka tātarihia e ngā whatukuhu te wai e hiahiatia ana, ā, ka tukuna hei mimi. Nō reira, ka ngaro te wai e hiahiatia ana e te tinana.

He aha ngā tohu o tēnei mate?

Ko ngā tohu matua me ngā tohu tino kitea o tēnei mate ko:

• Te matewai nui (polydipsia): Te āhua nei kāore koe i te matewai ahakoa te nui o te wai e inuhia ana e koe.
• Te mimi pinepine: Te hiahia kia ara ake i ngā wā maha ki te mimi, ehara i te mea i te awatea anake, engari i te pō anō hoki (nocturia).
• Te mimi nui rawa: He tino nui te mimi e whakaputaina ana. Kāore he tae o te mimi, he wai hoki.

He tohu kaha ēnei tohu e kī ana kāore tetahi mea e mahi tika ana i roto i tō tinana. Nō reira, ki te pā mai ēnei tohu ki a koe, he mea nui kia tere tonu te toro atu ki te tākuta.

He pēhea te puta o ēnei tohu i roto i ngā tamariki nohinohi?

Kāore pea ngā tamariki nohinohi e kaha ki te kī tika "E matewai ana ahau." Nō reira, ki te pāngia rātou e tēnei mate, tera pea ka rerekē te āhua o ngā tohu.

• Te matewai nui
• Te kōroke
• Ruaki
• Te kirika auau
• Te koretake me te tangi tonu
• Te kore e tupu pai (te kore e piki te taumaha)

He aha i puta ai tēnei āhuatanga?

He maha ngā take pea mō tēnei, kei te momo mate.

Ngā Take o te Kore Arginine Vasopressin (AVP-D)

Koinei te momo tino noa. Ka puta mai i te kino o ngā wāhanga o te roro e whakaputa ana i te homoni AVP (te hypothalamus, te pituitary gland rānei).

• Ngā whara o te upoko, ngā pokanga rānei: Ka pakaru pea ēnei wāhanga i te pokanga, i te aituā rānei o te roro.
• Ngā pukupuku: Nā ētahi pukupuku e puta mai ana i roto i te roro.
• Mumura: Ko ngā mate mumura e puta mai ana i ngā mate pēnei i te sarcoidosis, te kohi rānei.
• Ngā take ira: Ngā huringa ira tuku iho.
• Kāore i te mōhiotia te take: I ētahi wā, tata ki te haurua o ngā wā katoa, kāore e kitea he take motuhake .

Ngā Take o te Ātete ki te Arginine Vasopressin (AVP-R)

Kāore he raruraru ki te roro e whakaputa ana i te homoni, kei ngā whatukuhu te raruraru.

• Ngā take ira: Ngā raruraru ira ka tukuna iho i roto i ngā whakatipuranga.
• Ētahi rongoā: Tērā pea ētahi rongoā mō te mate hinengaro, pērā i te lithium.
• Te aukati i te ara mimi.
• Te pikinga o te taumata konupūmā i roto i te toto (Hypercalcemia).
• Te iti o te pāhare pāporo i roto i te toto (Hypokalemia).

Ngā āhuatanga motuhake e puta ana i te wā e hapu ana

He tino onge te pāngia o ngā wāhine e tēnei mate mō te wā poto i te wā e hapu ana. Nā te mea ka pakaru te homoni AVP o te whaea i te wā e hapu ana te whākōkī i hangaia e te whenua whānau. He nui ake tēnei mōrearea mō ngā whaea e whānau ana i ngā māhanga me ngā whaea he mate pēnei i te preeclampsia, e pā ana ki te mahi a te ate. Engari ko te rongo pai ko te nuinga o te wā ka ngaro katoa tēnei mate i roto i ngā wiki e rua ki te toru i muri i te whānautanga.

He aha ngā raruraru ka pā mai i tēnei?

Ko te raruraru nui me te tino morearea o tēnei āhuatanga ko te matewai , arā, ko te ngaronga o te wai me ngā electrolytes kia pai ai te mahi a te tinana.

I te nuinga o te wā, ka taea e koe te whakakapi i te ngaronga mā te inu i te wai e tika ana kia rite ki te nui o te mimi e whakaputaina ana e koe. Engari, ki te kore e taea e koe te inu i te wai e tika ana, ka tere tonu te matewai nui.

Me pēhea te kitenga a te tākuta i tēnei?

Tērā atu anō ngā mate e pāngia ai te matewai me te mimi. Hei tauira, ko te mate huka. Nō reira, ko te mea tuatahi ka mahia e te tākuta ko te tirotiro mō ētahi atu mate rite.

He maha ngā whakamātautau e mahia ana hei tautuhi tika i tēnei mate.

• Whakamātautau Kore Wai: Koinei te huarahi pono rawa atu hei tātaritanga i tēnei mate. I roto i tēnei whakamātautau, me mutu te inu wai mō ngā haora maha. Ka mahia tēnei i roto i te hōhipera i raro i te tirotiro tika a te tākuta, te nēhi rānei. Nā te mea ka matewai pea koe. Mena kei a koe tēnei mate, ka haere tonu tō tinana ki te whakaputa i te nui o te mimi ahakoa kāore koe i inu wai. Mō te tangata hauora, ka iti haere te putanga o tō mimi, ā, he iti noa te mimi kōwhai pouri, he kukū.
• Ētahi atu whakamātautau:
• Te tirotiro i ngā taumata huka toto (kia mōhio ai kāore koe i te mate huka).
• Te tātaritanga mimi - Tirohia te kukū (osmolality) o te mimi.
• Ngā whakamātautau toto - ine i tētahi mea e kiia nei ko Copeptin, e pā ana ki te homoni AVP.
• Matawai MRI - hei tirotiro mēnā he kino kei te repe pituitary, kei te hypothalamus rānei i roto i te roro.

He aha ngā maimoatanga mō tēnei?

Ko ngā kōwhiringa maimoatanga e whakawhirinaki ana ki te AVP-D, ki te AVP-R rānei kei a koe, engari ahakoa te maimoatanga, he mea nui te inu wai nui.

Te maimoatanga o te tūnga AVP-D

Ko te rongoā matua e whakamahia ana mō tēnei ko te Desmopressin . He homoni hangai tēnei e mahi ana hei whakakapi i te homoni AVP ngaro. Ka taea te tango hei pire, hei rehu ihu, hei werohanga rānei. I ētahi wā ka hoatu hoki mō ngā mate rangitahi e puta ana i te wā e hapu ana.

Te maimoatanga o te tūnga AVP-R

He ahua uaua te rongoā i tēnei. Nā te mea ehara te raruraru i konei i te korenga o ngā homoni, engari ko te korenga o ngā whatukuhu e aro ki aua homoni. Nō reira, me whakamahi ngātahi ngā maimoatanga rerekē.

• Ngā rongoā diuretic Thiazide: Ahakoa he momo rongoā ēnei e whakanui ana i te putanga mimi, he rerekē te mahi a ēnei rongoā i tēnei āhua, ā, ka whakaiti i te putanga mimi.
• Ngā rongoā anti-inflammatory kore-steroidal (NSAID): Ko ētahi rongoā kei roto i te wāhanga rongoā mamae.
• Mena i puta mai tēnei āhuatanga i tētahi atu rongoā e tangohia ana e koe, ka whakarerekētia taua rongoā e tō tākuta, ka tohua he rongoā anō.

He aha i hurihia ai te ingoa mai i te 'Diabetes Insipidus' ki te 'Diabetes Insipidus'?

He raruraru tēnei e pā ana ki te tini tāngata. Mō te wā roa, i tapaina tēnei mate ko te Diabetes Insipidus. Engari i te tau 2022, i huihui mai ētahi whakahaere hauora nui, ā, i whakatau kia hurihia tēnei ingoa.

Ko te take matua ko te pōhēhētanga i puta mai i te kupu "Diabetes". E whakamahia ana te kupu "Diabetes" hei tikanga mō te Diabetes Mellitus . He mate tino noa tēnei i tō tātou whenua. Ko tōna āhua he pikinga ake o te huka toto. Ahakoa he rite tonu ngā tohu o ngā mate e rua, arā, te matewai pinepine me te mimi, he tino rerekē ēnei mate e rua . He tino rerekē hoki ngā maimoatanga.

Nā te ingoa "Diabetes Insipidus" i hē ai te tautuhi i ētahi tūroro he mate huka tō rātou, ā, kua hē anō hoki te maimoatanga. Hei whakakore i tēnei pōhēhētanga, kua whakamahia te ingoa "Arginine Vasopressin Disorder" hei tohu mō te mate.

Ka taea te ora angitu me tēnei mate?

Ae, e tino taea ana. Ki te whiwhi koe i te maimoatanga tika mō tēnei mate, ā, ki te inu koe i te wai e tika ana kia rite ki ngā tohutohu a tō tākuta, kāore he raruraru nui e pā ki a koe.

Heoi, he nui ake te mōrearea o ētahi rōpū:

• Ngā pēpi iti
• Ngā tāngata neke atu i te 65 tau te pakeke
• Ngā tāngata whai raruraru hauora hinengaro, hauātanga whanaketanga rānei

Tērā pea ka uaua ki ēnei tāngata te mōhio he aha te wā e matewai ana rātou, e tono wai ana rānei i taua wā, ka nui ake ai te mōrearea o te matewai.

Ki te mea kei te noho tonu koe i roto i te wharepaku, ahakoa te nui o te inu, kāore e taea te whakamā i tō matewai, kia mahara he āhuatanga ngāwari tēnei. Ka whakawhanakehia e tō tākuta he mahere maimoatanga e tika ana māu. Māna anō hoki e kī atu ki a koe te nui o te wai me inu e koe i ia rā kia kore ai e matewai. Nō reira kaua e wehi ki te rapu tohutohu hauora.