Tiyeni tidziwe za mulingo wanu wa AST. (Aspartate Transferase - AST) Kodi zimenezo zikutanthauza chiyani?

Mwina mwawonapo mtengo wotchedwa AST pa lipoti la magazi, kapena mwamvapo dokotala akulankhula za izo. Ndiye, mwina mukudabwa kuti, "Kodi AST imatanthauza chiyani?" Musadandaule, tiyeni tikambirane mwachidule. Monga momwe mungalankhulire ndi mnzanu.

Kodi AST ndi chiyani? Mwachidule...

AST ndi dzina lalifupi la enzyme ya Aspartate Transferase . Nthawi zina imatchedwanso Aspartate Aminotransferase . Tsopano mwina mukudabwa kuti, "enzyme iyi ndi chiyani?"

Tangoganizirani, pali antchito ang'onoang'ono angapo mkati mwa matupi athu omwe amathandiza zinthu zosiyanasiyana kuti zigwire ntchito bwino. Ma enzyme ndi otere. Ndi mtundu wa puloteni. Enzyme iyi yotchedwa AST imapezeka m'malo ambiri m'thupi lathu. Imapezeka makamaka m'chiwindi . Koma kuwonjezera apo, enzyme iyi ya AST imapezeka m'maselo ena ambiri monga mtima, ubongo, kapamba, impso, ndi minofu. Komabe, nthawi zambiri, tikamalankhula za AST, nthawi zambiri imakhudzana ndi thanzi la chiwindi chathu.

Ndiye kodi kuyezetsa magazi kwa AST ndi chiyani?

Kuyezetsa magazi kwa AST kumayesa kuchuluka kwa AST m'magazi mwanu. Kawirikawiri, maselo a thupi lathu akawonongeka, enzyme iyi ya AST imatha kudziunjikira m'magazi. Chifukwa chake, kuchuluka kwa AST m'magazi ndi chizindikiro chakuti china chake sichili bwino m'thupi. Nthawi zambiri (koma osati nthawi zonse) izi zitha kukhala matenda a chiwindi.

Komabe, AST siipezeka m'chiwindi chokha. Chifukwa chake, zimakhala zovuta kwa dokotala kudziwa mtundu wa matenda omwe muli nawo kutengera kuchuluka kwa AST kokha. Nthawi zambiri, mayeso a AST amachitidwa limodzi ndi mayeso ena angapo. Mwachitsanzo, amachitidwa ngati gawo la gulu la enzyme ya chiwindi (HFP) kapena gulu la metabolic (CMP) . Izi zimakupatsani mwayi woyesa zinthu zambiri mu chitsanzo chimodzi cha magazi ndikupeza chithunzi chonse cha thanzi lanu.

Mayeso a AST ali ndi mayina ena angapo:

• Kutumiza kwa aspartate (AST).
• Aspartate aminotransferase (AST).
• Serum Glutamic-Oxaloacetic Transaminase (SGOT).
• SGOT.
• Aspartate transaminase.

Kodi kusiyana pakati pa AST ndi ALT ndi kotani?

Mwina munamvapo za mtengo wina wotchedwa ALT pamodzi ndi AST. ALT (Alanine Transferase) ndi enzyme ina yomwe imayesedwa m'chiwindi. Zonsezi zimatulutsidwa m'magazi maselo a chiwindi akawonongeka.

Komabe, mosiyana ndi AST, ALT ndi enzyme yomwe imapezeka makamaka m'chiwindi. AST imapezeka m'zigawo zina zambiri za thupi. Chifukwa chake, kuchuluka kwa ALT kumaonedwa ngati chizindikiro cha matenda a chiwindi kuposa kuchuluka kwa AST . Komabe, dokotala akamafufuza thanzi la chiwindi, nthawi zambiri amafufuza AST ndi ALT pamodzi.

Nchifukwa chiyani ndikufunika mayeso a AST?

Cholinga chachikulu cha mayeso a AST ndikupeza kuwonongeka kwa maselo m'thupi lathu. Izi zimathandiza kuzindikira mavuto a chiwindi, makamaka ngati maselo m'chiwindi awonongeka, chifukwa AST imasonkhana m'magazi. Komanso, monga tanenera kale, milingo ya AST imatha kukwera ngakhale maselo awonongeka kwina m'thupi.

Dokotala angakufunseni kuti muyesedwe mayeso a AST (nthawi zambiri ngati gawo la gulu) pazifukwa monga:

1. Kuwunika zizindikiro zisanawonekere

Anthu ena ali pachiwopsezo chachikulu chotenga matenda a chiwindi. Ngati muli ndi chimodzi mwa zinthuzi, mutha kuchita mayesowa kuti muwone ngati chiwindi chanu chili bwino musanayambe zizindikiro. Zinthuzi zikuphatikizapo:

• Kugwiritsa ntchito mowa mopitirira muyeso.
• Kukhala ndi matenda a chiwindi m'banja.
• Matenda a shuga.
• Kunenepa kwambiri (kuchuluka kwa mafuta m'thupi).
• Kubaya mankhwala pogwiritsa ntchito singano zomwe ena amagwiritsa ntchito.

Nthawi zina, mayeso a AST amaphatikizidwa mu Comprehensive Metabolic Panel (CMP) ngati gawo la kafukufuku wa thanzi, kotero mungafunike kuchita mayesowa ngakhale mutakhala kuti simuli pachiwopsezo cha matenda a chiwindi.

2. Yang'anirani vutoli (Kuyang'anira)

Ngati muli kale ndi matenda a chiwindi, dokotala wanu angakupatseni mayeso a AST kuti aone ngati akuchira, akuipiraipira, kapena ngati akuyenda bwino ndi chithandizo. Komanso, ngati mukumwa mankhwala omwe angakhudze chiwindi, mayesowa amachitidwanso kuti aone ngati mankhwalawo akuwononga chiwindi.

3. Monga chithandizo pa matenda (Kuzindikira)

Ngati muli ndi zizindikiro za matenda a chiwindi, mayeso a AST angaphatikizidwe mu mayesowo kuti akuthandizeni kuzindikira matendawo. Ngakhale kuti kuchuluka kwa AST kokha sikungathe kuzindikira matenda, ndi gawo lofunika kwambiri pa njira yodziwira matenda.

Zina mwa zizindikiro za matenda a chiwindi ndi izi:

• Kusanza ndi/kapena kusanza.
• Kupweteka m'mimba (kupweteka m'mimba).
• Khungu loyabwa.
• Jaundice (kutuluka kwachikasu pakhungu ndi maso oyera).
• Kumva kutopa pafupipafupi (kutopa).
• Chakudyacho sichikoma.

Ndani amayesa magazi a AST? Kodi amachitidwa bwanji?

Kawirikawiri, munthu amene waphunzitsidwa mwapadera kutenga magazi, wotchedwa phlebotomist, amatenga magazi amenewa. Komabe, dokotala aliyense wodziwa bwino ntchito yazaumoyo amene waphunzitsidwa kutenga magazi akhoza kuchita izi. Kenako chitsanzocho chimatumizidwa ku labu. Kumeneko, wasayansi wa ku labotale yachipatala amafufuza chitsanzocho ndikuyeza mulingo wa AST pogwiritsa ntchito makina apadera (analyzers).

Kodi pali chilichonse chomwe ndiyenera kuchita ndisanayese mayeso?

• Kusala Kudya: Ngati mayeso anu a AST ndi gawo la Comprehensive Metabolic Panel (CMP), mungapemphedwe kuti musadye kapena kumwa chilichonse kupatula madzi) kwa maola 10-12 musanayesedwe magazi. Komabe, ngati mukungoyezedwa magazi a AST kapena Hepatic Function Panel (HFP), nthawi zambiri simuyenera kusala kudya. Komabe,Tsatirani malangizo a dokotala wanu molondola.
• Chidziwitso cha Mankhwala: Muyenera kuuza dokotala wanu za mankhwala onse, mavitamini, ndi zowonjezera zomwe mukumwa. Mankhwala ena amatha kukhudza kuchuluka kwa AST. Dokotala wanu angakupempheni kuti musiye kumwa mankhwalawa masiku angapo mayeso asanachitike, pokhapokha mutauzidwa. Musasiye kumwa mankhwala aliwonse popanda upangiri wa dokotala wanu.

Kodi chimachitika n’chiyani mukapereka magazi?

Izi n'zosavuta kwambiri.

• Mudzakhala pampando. Kenako mtsempha woyenera udzapezeka m'dzanja lanu (nthawi zambiri pansi pa chigongono, mkati).
• Mtsempha ukapezeka, malowo amayeretsedwa ndi kutsukidwa ndi mankhwala ophera tizilombo.
• Kenako, singano yaying'ono imalowetsedwa mumtsempha umenewo ndipo magazi amatengedwa. Izi zitha kupweteka pang'ono, monga kulumidwa ndi nyerere.
• Pambuyo poika singano, magazi ochepa amasonkhanitsidwa mu chubu choyesera.
• Mukatha kusonkhanitsa magazi okwanira kuti muyesedwe, chotsani singanoyo ndikuyika mphamvu pamalo omwe magazi atuluka ndi thonje kapena gauze kuti magazi asiye kutuluka.
• Kenako, pulasitala imayikidwa pamalopo ndipo ntchitoyo yatha.

Njira yonseyi nthawi zambiri imatenga mphindi zosakwana zisanu.

Kodi chimachitika n’chiyani munthu akapereka magazi?

Magazi akatumizidwa ku labu, zotsatira zake zidzapezeka patatha tsiku limodzi kapena awiri. Nthawi zina zimatenga nthawi yayitali. Dokotala wanu adzakuuzani za zotsatira zake akabwera.

Kodi pali chiopsezo chilichonse pa izi?

Kuyezetsa magazi ndi njira yodziwika bwino komanso yofunika kwambiri. Kuopsa kwake n'kochepa kwambiri. Pakhoza kukhala mabala ndi kupweteka komwe magazi amatengedwa. Koma zimenezo zimatha msanga.

Kodi zotsatira za mayeso a AST zikutanthauza chiyani?

Lipoti la kuyezetsa magazi nthawi zambiri limaphatikizapo mfundo zotsatirazi pamodzi ndi zotsatira za AST:

• Dzina la mayeso a magazi (limatchedwa AST).
• Kuchuluka (mtengo) wa AST m'magazi anu.
• Mlingo wabwinobwino wa mayeso amenewo.
• Kaya zotsatira zanu ndi zabwinobwino kapena zoyipa (zokwera kapena zochepa).

Kodi AST ndi yotani nthawi zonse?

Mlingo wabwinobwino wa AST ukhoza kusiyana pang'ono kuchokera ku labu imodzi kupita ku ina. Mlingo wamba wamba ndi 8 mpaka 33 U/L (mayunitsi/lita) . Komabe, ndikofunikira kuyang'ana muyezo wabwinobwino pa lipoti lanu.

Komanso, kumbukirani, palibe mulingo umodzi wa AST "wabwinobwino" womwe umagwira ntchito kwa aliyense. Mulingo wabwino wa AST ukhoza kusiyana kutengera zinthu monga:

• zaka zanu.
• Ukazi/umuna wanu.
• Mtundu wanu.
• Kulemera kwanu.

Dokotala wanu adzaganizira zonsezi ndikusankha zotsatira zake.

Kodi zikutanthauza chiyani ngati mlingo wanga wa AST uli wokwera?

Ngati AST yakwera, ikhoza kukhala chizindikiro cha matenda a chiwindi.Ngati mayeso ena a magazi, makamaka okhudzana ndi chiwindi, nawonso ndi osazolowereka, ndiye kuti muli ndi matenda a chiwindi. Komabe, monga tanenera kale, kuchuluka kwa AST kumatha kukwera ngati maselo m'zigawo zina za thupi awonongeka, makamaka m'chiwindi.

Kuwonjezeka kwa AST m'magazi kungasonyeze matenda a chiwindi monga:

• Kuwonongeka kwa chiwindi chifukwa cha mowa.
• Matenda a chiwindi.
• Kutupa kwa chiwindi (Cirrhosis).
• Kumwa mankhwala owopsa (oopsa) ku chiwindi.
• Chotupa cha chiwindi kapena khansa ya chiwindi.
• Kuchepa kwa magazi kupita ku chiwindi (Liver Ischemia) (izi zingayambitse kufa kwa minofu ya chiwindi).

Kuphatikiza apo, matenda omwe sakhudzana mwachindunji ndi chiwindi angayambitsenso kuchuluka kwa AST:

• Kuchuluka kwa chitsulo m'thupi (Hemochromatosis) (izi zimawononga mtima, chiwindi, ndi kapamba).
• Matenda a mtima (Myocardial Infarction).
• Mononucleosis ndi malungo.
• Matenda a minofu.
• Kutupa kwa kapamba (pancreatitis).

Kuwonjezera pa zinthu izi, milingo ya AST imathanso kukwera kwakanthawi pambuyo pa zochitika monga:

• Kupsa kwambiri.
• Kugwedezeka.
• Maopaleshoni kapena njira zokhudzana ndi mtima.
• Opaleshoni.
• Kuchita masewera olimbitsa thupi mwamphamvu.
• Ngati muli ndi pakati.

Chofunika kwambiri ndichakuti kuchuluka kwa AST sikutanthauza kuti muli ndi matenda aakulu. Zinthu zina zambiri zingakhudze izi. Dokotala wanu adzayang'ana mayeso ena a magazi, mbiri yanu yachipatala, ndi zina zonse kuti atsimikizire.

Kodi ndiyenera kuda nkhawa ngati zotsatira zanga za AST zili pamwamba?

Ngati mulingo wanu wa AST uli wapamwamba kuposa mulingo wamba womwe waperekedwa pa lipoti lanu la mayeso a AST, sizitanthauza kuti muli ndi matenda omwe amafunika chithandizo. Ngakhale munthu amene ali ndi chiwindi chathanzi komanso chogwira ntchito bwino akhoza kukhala ndi mulingo wa AST woposa mulingo wamba. Izi zitha kukhala pazifukwa zambiri, mwachitsanzo:

• zaka zanu.
• Ukazi/umuna wanu.
• Mtundu wanu.
• Zakudya zanu.
• Kuchita masewera olimbitsa thupi.
• Kumwa mankhwala omwe amakhudza kuchuluka kwa AST.
• Uli ndi pakati.

Dokotala wanu adzaganizira zonsezi, pamodzi ndi zotsatira zina za mayeso anu a magazi, ndikusankha ngati mukufuna kuyezetsa kwina.

Ngati zotsatira zanga za AST sizili bwino, kodi ndiyenera kuyesedwanso?

Inde, ngati mulingo wanu wa AST ndi wolakwika, dokotala wanu angakupatseni mayeso ena angapo. Mayesowa akuphatikizapo:

• Bwerezani mayeso a magazi a AST.
• Mayeso ena a magazi (monga ALT, Bilirubin).
• Mayeso owunikira (monga Ultrasound scan).
• Kujambula kwa magazi.

Kodi ndiyenera kuyimbira dokotala liti?

• Ngati muli ndi zizindikiro za kuwonongeka kwa chiwindi (monga jaundice, kupweteka m'mimba), imbani dokotala nthawi yomweyo.
• Ngati mukudziwa kale kuti muli ndi matenda a chiwindi, uzani dokotala wanu ngati mukuyamba zizindikiro zatsopano kapena zodetsa nkhawa.
• Ngati muli ndi mafunso okhudza zotsatira za AST, musaope kufunsa dokotala wanu.

Chinthu chofunika kwambiri kukumbukira (Uthenga Wopita Nawo Kunyumba)

Ndizachilendo kukhala ndi nkhawa pang'ono mukaona kuchuluka kwa magazi kosazolowereka. Koma kumbukirani, kungoti kuchuluka kwa AST yanu kwakwera sizikutanthauza kuti muli ndi matenda kapena mukufuna chithandizo. Zinthu zambiri zingakhudze kuchuluka kwa AST. Pafupifupi munthu m'modzi mwa anthu 20 athanzi akhoza kukhala ndi zotsatira zoposa zomwe zinali zoyenera.

Dokotala wanu adzasankha ngati mukufunika kuchita mayeso ena kuti apeze chomwe chikuyambitsa vuto lachilendoli. Choncho, musaope kulankhula ndi dokotala wanu za izi. Alipo kuti akuthandizeni. Mwamvetsa?

AST , chiwindi, ma enzyme, kuyezetsa magazi, SGOT, matenda a chiwindi, kuyezetsa thanzi