Kodi nthawi zonse mumatopa? Kodi khungu lanu limasintha kukhala lakuda? Tiyeni tiphunzire za Matenda a Addison!

Kodi mumamva kutopa nthawi zonse, kumva ngati mulibe moyo, ndipo khungu lanu likusintha pang'onopang'ono? Mwina muli ndi chilakolako chachilendo cha mchere. Nthawi zambiri timanyalanyaza zizindikiro ngati zachilendo. Komabe, izi zitha kukhala zizindikiro za matenda omwe si ofala m'thupi lathu, koma ndikofunikira kwambiri kuwazindikira bwino. Lero tikulankhula za matenda osowa kwambiri, koma ngati atathandizidwa bwino, mutha kukhala moyo wabwinobwino. Umenewo ndi Matenda a Addison .

Mwachidule, kodi matenda a Addison ndi chiyani?

Chabwino, tiyeni tifotokoze izi mosavuta. Tili ndi tiziwalo tiwiri tating'onoting'ono tooneka ngati katatu, ngati chipewa, pamwamba pa impso zathu. Timatcha izi kuti tiziwalo ta adrenal . Izi ndi gawo lofunika kwambiri la dongosolo lathu la endocrine.

Matenda a Addison ndi matenda omwe ma adrenal glands sapanga mahomoni awiri ofunikira okwanira, cortisol ndi aldosterone .

Kodi timafunikira mahomoni awiriwa chifukwa chiyani?

• Cortisol: Iyi ndi homoni yofunika kwambiri pa moyo. Imathandiza matupi athu kuthana ndi kupsinjika maganizo, monga tikadwala, tikachita ngozi, kapena tikachitidwa opaleshoni. Imathandizanso kuwongolera kuthamanga kwa magazi, kugunda kwa mtima, kugwira ntchito kwa chitetezo chamthupi, komanso kuchuluka kwa shuga m'magazi.

• Aldosterone: Homoni iyi imathandiza kulinganiza mchere wa sodium (mchere) ndi potaziyamu m'thupi lathu. Imawongoleranso kuchuluka kwa madzi omwe impso zathu zimatulutsa ngati mkodzo. Izi zimakhudzanso kuthamanga kwa magazi athu mwachindunji.

Matenda a Addison amadziwikanso kuti primary adrenal insufficiency . Palinso vuto lina lofanana nalo, lotchedwa secondary adrenal insufficiency . Mu vutoli, pituitary gland muubongo situlutsa mahomoni okwanira a ACTH , omwe amalimbikitsa adrenal glands kupanga cortisol. Koma lero tikulankhula makamaka za vuto lomwe limapezeka mu adrenal glands okha.

Kusiyana pakati pa matenda a Addison ndi matenda a Cushing

Mungasokonezeke ndi mayina awiriwa. Mayina awiriwa ndi osiyana kwambiri.

Ndani amene ali ndi mwayi waukulu wopeza matendawa? Kodi ndi ofala bwanji?

Ngakhale matenda a Addison amatha kuchitika pa msinkhu uliwonse, amapezeka kwambiri mwa anthu azaka zapakati pa 30 ndi 50 .

Izi ndi matenda osowa kwambiri . Mwachitsanzo, ku America, matendawa amakhudza munthu m'modzi pa anthu 100,000. Koma palinso anthu omwe ali ndi matendawa m'dziko lathu.

Pali anthu omwe ali pachiwopsezo chachikulu chotenga matendawa. Anthuwa ndi omwe ali ndi matenda ena odziteteza okha . Ndiko kuti, matenda omwe chitetezo cha mthupi lathu chimaukira maselo athu. Ngati tili ndi matenda otere, chiopsezo chotenga matenda a Addison chimakhala chachikulu.

• Matenda a shuga amtundu woyamba
• Kuchepa kwa magazi m'thupi koopsa
• Matenda a Manda
• Matenda a chithokomiro chosatha
• Vitiligo - mawanga oyera pakhungu
• Myasthenia gravis

Kodi zizindikiro za matenda a Addison ndi ziti?

Mu matenda a Addison, kuwonongeka kwa adrenal glands nthawi zambiri kumachitika pang'onopang'ono, pakapita nthawi. Chifukwa chake, zizindikiro zimawonekera pang'onopang'ono. Zizindikirozi zimatha kusiyana malinga ndi munthu.

Azimayi amathanso kukhala ndi zizindikiro monga kusamba kosakhazikika, kutayika tsitsi m'thupi, komanso kuchepa kwa chilakolako chogonana.

Zizindikiro za vuto la Addisonian:

• Kufooka kosapiririka komanso kodabwitsa.
• Kupweteka kwadzidzidzi, koopsa m'munsi mwa msana, m'mimba, kapena m'miyendo.
• Kusintha kwa maganizo monga kusakhazikika, chisokonezo, ndi mantha.
• Kusanza kwambiri ndi kutsegula m'mimba (izi zingayambitse kutaya madzi m'thupi mwachangu).
• Kuthamanga kwa magazi kumatsika kwambiri.
• Kutaya chidziwitso.

Ngati inuyo kapena munthu amene mumamudziwa akukumana ndi zizindikiro zimenezi, pitani naye ku Dipatimenti Yothandiza Anthu Pangozi (ETU) ya chipatala chapafupi nthawi yomweyo.

Kodi ndi zifukwa ziti zomwe zimayambitsa matenda a Addison?

Chifukwa chachikulu komanso chofala kwambiri cha matenda a Addison ndi kuyankha kwa autoimmune.Mwachidule, chitetezo chathu (chitetezo cha mthupi) chimaukira molakwika ndikuwononga gawo lakunja la ma adrenal glands athu (adrenal cortex). Chifukwa chenicheni chomwe izi zimachitikira sichikudziwikabe. Zizindikiro zimayamba kuonekera pambuyo poti pafupifupi 90% ya ma adrenal glands awa awonongeka. Izi zitha kutenga miyezi, kapena zaka.

Ichi ndi chomwe chimayambitsa 75% ya odwala a Addison.

Zina mwa zifukwa zachilendo:

• Chifuwa chachikulu: Ichi chinali chifukwa chachikulu m'mbuyomu. Chidakali chifukwa chachikulu m'maiko osatukuka.
• Matenda obwerezabwereza: Matenda okhudzana ndi HIV/AIDS ndi matenda a bowa.
• Khansa: Kufalikira kwa maselo a khansa kuchokera kwina kupita ku adrenal glands.
• Kutuluka magazi m'zidutswa za adrenal.
• Kuchotsa adrenal glands ndi opaleshoni.
• Amyloidosis: Matenda omwe mtundu wina wa mapuloteni umasonkhana m'ziwalo ndikuziwononga.

Kodi mungazindikire bwanji matendawa? (Kuzindikira)

Popeza zizindikiro zimabwera pang'onopang'ono kwambiri ndipo zimakhala zofala ku matenda ena ambiri, matenda a Addison amatha kukhala ovuta kuwazindikira pachiyambi. Nthawi zambiri, matendawa amapezeka "mwangozi." Madokotala angakayikire izi ngati apeza sodium yochepa komanso potaziyamu yambiri m'magazi panthawi yoyezetsa magazi nthawi zonse kuti adziwe vuto lina. Komanso, kuchuluka kwa pigment pakhungu ndi chizindikiro chachikulu chomwe chimayambitsa kukayikira matendawa.

Ngati dokotala wanu akukayikira izi kutengera zizindikiro zanu, adzayitanitsa mayeso ena angapo kuti atsimikizire matendawa.

Mayeso ozindikira matenda:

• Kuyezetsa magazi: Kuyezetsa magazi kumayesa kuchuluka kwa sodium, potaziyamu, cortisol, ndi mahomoni a ACTH. Mu matenda a Addison, cortisol ndi yotsika ndipo kuchuluka kwa ACTH ndi kwakukulu.
• Mayeso olimbikitsa ACTH: Iyi ndiye mayeso akuluakulu omwe amagwiritsidwa ntchito kutsimikizira matendawa. Mu mayesowa, mahomoni opangidwa a ACTH amaperekedwa ngati jakisoni, ndipo kuchuluka kwa cortisol m'magazi anu kumayesedwa patatha ola limodzi. Ngati adrenal glands yanu ili ndi thanzi labwino, kuchuluka kwa cortisol yanu kuyenera kukwera. Komabe, ngati sichoncho, zimatsimikizira kuti adrenal glands yanu sikugwira ntchito bwino.
• Kuyesa kwa hypoglycemia komwe kumachitika chifukwa cha insulin: Kuyesaku kumachitika kuti mudziwe ngati zizindikiro zanu zayamba chifukwa cha vuto la pituitary gland.
• Kujambula kwa CT: Kujambula kwa CT kungachitike kuti muwone ngati adrenal glands yanu yawonongeka, yadwala, kapena yachepa kukula kwake.

Kodi chimachiritsidwa bwanji?

Njira yaikulu yochiritsira matenda a Addison ndi,Chithandizo Chosintha Mahomoni (HRT) ndi njira yosinthira mahomoni osowa m'thupi mwa kupanga mapiritsi opangidwa.

• Mankhwala otchedwa hydrocortisone amaperekedwa m'malo mwa hormone ya cortisol .
• Mankhwala otchedwa fludrocortisone amaperekedwa m'malo mwa hormone ya aldosterone .

Mlingo wa mankhwala awa umasiyana malinga ndi munthu. Komanso, dokotala wanu angakuwonjezereni kwakanthawi kuti apewe vuto la Addisonian ngati mukukumana ndi vuto lopsinjika, monga matenda, ngozi, kapena opaleshoni.

Ngati mukumwa fludrocortisone, dokotala wanu adzakulangizani kuti muwonjezere mchere pang'ono muzakudya zanu, makamaka nthawi yotentha, thukuta komanso mukatha kuchita masewera olimbitsa thupi.

Kukhala ndi matendawa ndi zomwe muyenera kuchita

Ndi chithandizo choyenera, munthu amene ali ndi matenda a Addison akhoza kukhala ndi moyo wabwinobwino komanso wathanzi . Komabe, ndikofunikira kwambiri kusunga mlingo woyenera wa mankhwala.

Ngati mlingo wa mankhwalawo ndi wokwera kwambiri, zotsatirapo zake monga kunenepa kwambiri, matenda a shuga amtundu wachiwiri, kufooka kwa mafupa, ndi kuthamanga kwa magazi zimatha kuchitika. Chifukwa chake, ndikofunikira kukaonana ndi dokotala nthawi zonse (nthawi zambiri katswiri wa endocrinologist) ndikuyesedwa kofunikira kuti musunge mlingo woyenera wa mankhwalawo.

Zinthu zomwe muyenera kuchita kuti mukhale otetezeka:

• Nthawi zonse valani chiphaso cha ID kapena chibangili/mkanda wa chenjezo la zachipatala. Izi zithandiza ogwira ntchito zachipatala kudziwa kuti muli ndi matenda a Addison ngati mutataya chikumbumtima mwadzidzidzi.
• Lankhulani ndi dokotala wanu za kukhala ndi jakisoni wa cortisol pafupi ngati pachitika ngozi. Komanso, phunzitsani wachibale wanu kapena wokondedwa wanu momwe angakupatsireni jakisoni.
• Funsani dokotala wanu zomwe mungachite mukakhala kuti mukudwala kapena muli ndi nkhawa kwambiri. Zikatero, mlingo wa mankhwala anu ungafunike kusinthidwa.
• Pitirizani kukaonana ndi dokotala wanu.

Kudziwa kuti muli ndi matenda osatha kungakhale kovuta kwambiri m'maganizo. Koma nkhani yabwino ndi yakuti matenda a Addison amathetsedwa bwino ndi mankhwala. Chofunika kwambiri ndikulankhulana ndi dokotala nthawi zonse ndikupeza chithandizo chomwe mukufuna.