Tonsefe timadziwa mantha ndi nkhawa zomwe zimadza chifukwa chomva kuchokera kwa dokotala kuti wachibale kapena mnzanu ali ndi vuto lalikulu la magazi kapena khansa ya magazi. Koma chifukwa cha kupita patsogolo kwa zamankhwala masiku ano, pali mankhwala amphamvu omwe angachiritse matenda otere. Chithandizo chimodzi chopulumutsa moyo chotere chimatchedwa "Allogeneic Stem Cell Transplant." Ngakhale dzinalo lingamveke lovuta, tiyeni tikambirane zomwe zimachitika mu izi mosavuta .
Kodi kusintha maselo oyambira a allogeneic ndi chiyani kwenikweni?
Mwachidule, izi zikuphatikizapo kuchotsa maselo oyambira omwe ali ndi matenda komanso osagwira ntchito bwino m'thupi lanu ndikuyika maselo oyambira athanzi komanso oyenera kuchokera kwa wina (wopereka).
Tsopano tiyeni tifotokoze izi pang'ono.
- Maselo Oyambira: Tingathenso kuwatcha "maselo amayi" chifukwa maselowa ali ngati fakitale yomwe imapanga maselo ena onse amagazi m'thupi lathu (maselo ofiira amagazi, maselo oyera amagazi, ma platelet). Maselo oyambira awa amapezeka kwambiri m'mafupa athu.
- Allogeneic: Liwu limeneli limatanthauza "kulandira kuchokera kwa wina." Izi zikutanthauza kuti chithandizocho chimagwiritsa ntchito maselo ochokera kwa wopereka wathanzi komanso wogwirizana, osati anu.
Tangoganizani kuti mafuta athu a m'mafupa ali ngati munda wobala bwino wokhala ndi nthaka yabwino. M'munda uwu ndi momwe maselo athu a m'magazi amakulira. Koma mu matenda monga khansa ya m'magazi, munda uwu umawonongeka, ndipo udzu (maselo a khansa) umamera m'malo mwa mbewu zabwino. Choncho, mu chithandizo ichi, nthaka yowonongeka (mafupa odwalitsidwa) imachotsedwa kwathunthu ndikusinthidwa ndi nthaka yatsopano, yathanzi, komanso yobala bwino (maselo oyambira a wopereka). Kenako, maselo athanzi a m'magazi amayamba kukula m'nthaka yatsopanoyo.
Mankhwalawa ndi amphamvu kwambiri ndipo amatha kuchiritsa matenda ena akuluakulu. Madokotala nthawi zambiri amagwiritsa ntchito mankhwalawa ngati njira zina zalephera kapena matendawa akabwereranso.
Kodi chithandizochi chimagwiritsidwa ntchito pa matenda amtundu wanji?
Kawirikawiri amagwiritsidwa ntchito pa matenda okhudzana ndi magazi ndi chitetezo chamthupi. Nazi zina mwa matenda akuluakulu.
| Matenda | Kufotokozera kosavuta |
|---|---|
| Khansa ya m'magazi ya Lymphoblastic (YONSE) | Ma lymphocyte, mtundu wa maselo oyera a m'magazi omwe amapezeka m'magazi ndi m'mafupa, amakhala maselo a khansa. |
| Matenda a Myeloid Leukemia (AML) | Khansa ya maselo a m'magazi omwe amapangidwa kuchokera ku maselo oyambira a myeloid. |
| Kuchepa kwa magazi m'thupi | Kuwonongeka kwa mafuta a m'mafupa kumalepheretsa thupi kupanga maselo atsopano a magazi okwanira. |
| Lymphoma | Khansa yomwe imapezeka mu dongosolo la lymphatic. |
| Matenda a Myelodysplastic | Kupanga kosakhazikika kwa maselo a magazi abwino m'mafupa. |
| Matenda a Sickle Cell | Matenda obadwa nawo omwe mawonekedwe a maselo ofiira a magazi amasintha ndipo ntchito yawo imasokonekera. |
Kodi mumakonzekera bwanji chithandizo?
Popeza uwu ndi chithandizo chachikulu, gulu lachipatala lidzayesa mayeso angapo pasadakhale kuti litsimikizire kuti thupi lanu likhoza kupirira.
- Kuyezetsa magazi: Zinthu monga kuwerengera magazi kwathunthu (CBC) kumachitika kuti muwone kuchuluka kwa maselo ofiira a magazi, maselo oyera a magazi, ndi ma platelet.
- Mayeso a mtima: Echocardiogram (kuti muwone momwe mtima ukugwira ntchito) ndi electrocardiogram (EKG) kuti muwone kayendedwe ka mtima.
- Mayeso amachitika kuti aone momwe chiwindi ndi impso zimagwirira ntchito .
- Kufufuza za Mafupa: Ngati muli ndi khansa, mumatengedwa chitsanzo cha mafupa ndikuyesedwa kuti muwone mtundu wa matendawa komanso chiopsezo chobwereranso.
Mayeso onsewa akangochitika ndipo zadziwika kuti ndinu woyenera, gawo lofunika kwambiri la chithandizo, lotchedwa "pre-transplant conditioning," limayamba. Izi zimaphatikizapo mankhwala amphamvu kwambiri a chemotherapy kapena radiation therapy ku thupi lonse. Nthawi imeneyi ingakhale yovuta. Koma ndi yofunika kwambiri.
N’chifukwa chiyani chithandizochi chisanachitike n’chofunika kwambiri?
- Zimawononga maselo onse a khansa otsala m'thupi lanu.
- Imachotsa maselo akale, odwala m'mafupa anu ndipo imapangitsa kuti maselo atsopano akule.
- Zimafooketsa chitetezo chamthupi chanu kwakanthawi. Izi zimachitika kuti thupi lanu lisaukire ndikukana maselo atsopano omwe aperekedwa.
Muyenera kukhala m'chipatala kwa sabata imodzi kapena ziwiri kuti mupeze chithandizochi.
Kodi chimachitika ndi chiyani tsiku lomwe maselo amasamutsidwa?
Njira yoika maselo m'thupi ndi yosavuta komanso yopanda ululu , monga kupereka magazi.
Gulu lachipatala lidzaika chubu chapadera mu mtsempha waukulu pachifuwa chanu chapamwamba. Ichi chimatchedwa Central Venous Catheter (CVC) . Thumba lomwe lili ndi maselo athanzi ochokera kwa wopereka limalumikizidwa ku chubu ichi. Kenako maselowo amalowetsedwa pang'onopang'ono m'thupi lanu, kudzera m'magazi anu, komanso m'mafupa anu, ngati madzi amchere.
Izi zimatenga mphindi 30 mpaka ola limodzi. Panthawiyi, gulu lachipatala lidzakhala pafupi nanu ndikuyang'anira kuthamanga kwa magazi ndi kugunda kwa mtima wanu. Nthawi zina, zotsatirapo zazing'ono zingachitike.
- Kumva kuzizira
- Kuvuta pang'ono kupuma
- Malungo
Koma nthawi zambiri izi sizikhala zazikulu.
Kodi chimachitika ndi chiyani mukalandira chithandizo?
Nthawi yofunika kwambiri yochira imayamba mutabzala selo loyamba. Muyenera kukhala m'chipatala kapena pafupi nacho kwa milungu ingapo.
- Kulamulira chitetezo chamthupi: Mudzapitiriza kupatsidwa mankhwala oletsa chitetezo chamthupi kuti thupi lanu lisaukire maselo atsopano komanso kuti maselo atsopano asaukire thupi lanu.
- Kuika magazi: Zimatenga nthawi kuti maselo atsopano ayambe kugwira ntchito ndikupanga maselo ofiira ndi ma platelet atsopano. Panthawi imeneyo, mungafunike kuikidwa magazi.
- Chitetezo ku matenda: Chitetezo cha mthupi lanu chimakhala chofooka kwambiri panthawiyi, choncho chisamaliro chapadera chimaperekedwa kuti mudziteteze ku matenda a bakiteriya ndi mavairasi.
Njira imene maselo atsopano amayendera kupita ku mafupa, kukhazikika pamenepo, ndikuyamba kupanga maselo atsopano a magazi imatchedwa "engraftment." Izi zingatenge masiku 10 mpaka 14.
Kodi zimatenga nthawi yayitali bwanji kuti munthu achire bwino?
Iyi ndi njira yayitali. Zingatenge zaka ziwiri kapena kuposerapo kuti munthu achire bwino. Zingatenge pafupifupi chaka chimodzi kuti chitetezo cha mthupi chanu chibwererenso.
Zoopsa zapadera zomwe muyenera kuzidziwa: Matenda a Graft vs. Host (GVHD)
Imeneyi ndi vuto lofala kwambiri la kuikidwa kwa allogeneic. Mwachidule, zimachitika pamene maselo atsopano a chitetezo chamthupi ochokera kwa wopereka (chomera) akuukira maselo ndi minofu ya thupi lanu (chomera) . Zili ngati "mlendo akuukira chomera."
Izi zitha kukhala zofatsa kapena zowopsa. Ichi ndichifukwa chake mankhwala oletsa chitetezo chamthupi amaperekedwa nthawi zonse. Muyenera kudziwa bwino zizindikiro za vutoli.
Zizindikiro zomwe ziyenera kufotokozedwa kwa dokotala nthawi yomweyo
Mukapita kunyumba mutalandira chithandizo, muyenera kusamala kwambiri ndi zizindikiro zina. Ngati chimodzi mwa izi chikuwonekera, imbani gulu lanu lachipatala nthawi yomweyo.
| Gulu la zizindikiro | Zinthu zofunika kuziganizira |
|---|---|
| Zizindikiro za matenda a Graft vs. Host Disease (GVHD) zingaphatikizepo: | |
| Mimba | Kupweteka m'mimba, nseru ndi kusanza, kutsegula m'mimba (kudzimbidwa) |
| Khungu ndi maso | Kuyabwa pakhungu, chikasu cha khungu ndi/kapena maso (jaundice) |
| Zingakhale zizindikiro za matenda | |
| Makhalidwe Abwino | Malungo a madigiri 38 Celsius (100.4 Fahrenheit) kapena kupitirira apo, kuzizira |
| Mapumulo | Kutsokomola, kuyetsemula, mphuno yotuluka madzi, kupuma movutikira |
| Zina mwazinthu | Chizungulire, kufuna kukodza pafupipafupi, kapena kutentha kwambiri mukakodza |
Kusiyana pakati pa "allogeneic" ndi "autologous" transplants
Mwina munamvapo za kusamutsa maselo oyambira a autologous . Kusiyana kwakukulu pakati pa awiriwa ndi komwe maselowo adachokera.
- Allogeneic: Maselo amachokera kwa munthu wina (wopereka).
- Autologous: Maselo amatengedwa kuchokera kwa wodwalayo . Izi zikutanthauza kuti maselo athanzi a wodwalayo amasonkhanitsidwa kaye kenako amabwezeretsedwa kwa iwo pambuyo pa mankhwala amphamvu a chemotherapy.
Kuika munthu m'thupi pogwiritsa ntchito njira ya allogeneic kungachiritse matenda ena omwe amapha anthu ambiri. Nthawi zambiri, kuika munthu m'thupi pogwiritsa ntchito njira imeneyi kumachitidwa ndi anthu osadziwika omwe sitinakumanepo nawo. Nthawi zina, achibale amakhala opereka chithandizo. Ngakhale kuti pali zoopsa pa chithandizochi, ubwino wake ndi waukulu kwambiri. Dokotala wanu adzakufotokozerani zonsezi ndikuthandizani kupanga chisankho chomwe chili chabwino kwa inu.
Uthenga Wopita Nawo Kunyumba
- Kusamutsa maselo oyambira a allogeneic ndikusintha mafuta oyambira omwe ali ndi matenda ndi maselo oyambira ochokera kwa wopereka wathanzi.
- Uwu ndi mankhwala amphamvu omwe amagwiritsidwa ntchito pa matenda oopsa a magazi monga khansa ya m'magazi, lymphoma, ndi aplastic anemia.
- Ndikofunikira kukonzekera thupi ndi mankhwala amphamvu a chemotherapy kapena radiation musanalandire chithandizo.
- Vuto lalikulu lomwe lingachitike mutalandira chithandizo ndi matenda a Graft vs. Host Disease (GVHD), ndipo ndikofunikira nthawi zonse kudziwa izi ndi zizindikiro za matenda.
- Iyi ndi njira yayitali yochiritsira, ndipo ndikofunikira kwambiri kudziwitsa dokotala wanu kapena gulu lachipatala nthawi yomweyo za vuto lililonse.
💬 Comments (0)
Palibe ndemanga zomwe zatumizidwa pano. Onjezani ndemanga yanu pano koyamba.
Onjezani ndemanga yanu