Mapiritsi a Alpelisib (Vijoice): mankhwala a matenda a PROS (PIK3CA-Related Overgrowth Spectrum)

Kodi inu kapena mwana wanu muli ndi vuto lotchedwa PROS? Madokotala amalitcha PIK3CA-Related Overgrowth Spectrum. Mwachidule, ndi vuto lomwe minofu m'mbali zina za thupi imakula modabwitsa komanso mwachangu. Ndi vuto losowa, ndipo limakhala lovuta kulithetsa. Koma lero tikambirana za mankhwala omwe angagwiritsidwe ntchito pochiza. Ndi piritsi lotchedwa Alpelisib. Tiyeni tiwone chomwe mankhwalawa ndi, momwe amagwirira ntchito, komanso zomwe muyenera kusamala nazo mukamamugwiritsa ntchito.

Kodi mankhwala awa otchedwa Alpelisib ndi ati?

Alpelisib (dzina lodziwika bwino la Vijoice) ndi mankhwala omwe amagwiritsidwa ntchito poletsa zizindikiro za PROS. Pali puloteni m'thupi lathu yomwe imathandiza maselo kukula ndikugawikana. Mwa anthu omwe ali ndi PROS, njirayi ndi yochulukirapo. Chifukwa chake chomwe mankhwalawa amachita ndikuletsa ntchito ya puloteni yomwe imayambitsa kukula kwa maselo mwachangu. Kenako kukula kosafunikira kwa minofu kumawongoleredwa kwambiri. Izi zimathandiza kuchepetsa zizindikiro ndikupangitsa moyo kukhala wosavuta.

Zinthu zomwe muyenera kuuza dokotala wanu musanayambe kumwa mankhwala

Musanayambe kugwiritsa ntchito Alpelisib, ndikofunikira kwambiri kulankhula ndi dokotala wanu momasuka za thanzi lanu. Onetsetsani kuti mwawauza zinthu izi makamaka:

• Matenda a shuga: Uzani dokotala wanu ngati inu kapena wina m'banja mwanu ali ndi matenda a shuga.
• Matenda a m'mapapo: Ngati muli ndi vuto lililonse lokhudzana ndi mapapo.
• Matenda a ziwengo: Tiuzeni ngati muli ndi vuto lililonse la ziwengo ku Alpelisib kapena mankhwala ena aliwonse, chakudya, kapena utoto.
• Mimba: Ndikofunikira kuuza dokotala wanu ngati muli ndi pakati, mukufuna kutenga mimba, kapena ngati mnzanuyo ali ndi mwayi wokhala ndi pakati.
• Kuyamwitsa: Ngati mukuyamwitsa, onetsetsani kuti mwatchulanso zimenezo.

Kutengera ndi izi, dokotala adzasankha ngati mankhwalawa ndi oyenera kwa inu kapena ayi.

Kodi mumagwiritsa ntchito bwanji mankhwalawa molondola?

Ndikofunikira kwambiri kutsatira malangizo a dokotala wanu momwe mungagwiritsire ntchito mankhwalawa.

• Mapiritsi awa ayenera kumwedwa pakamwa. Imwani pamodzi ndi chakudya .
• Khalani ndi chizolowezi chomwa mankhwala anu nthawi yomweyo tsiku lililonse. Mwanjira imeneyi, simudzayiwala.
• Musaswe kapena kutafuna piritsi. Mezani lonse.
• Pitirizani kugwiritsa ntchito mankhwalawa mpaka dokotala wanu atakuuzani kuti musiye.

Kodi mumatani ngati wina akuvutika kumeza mapiritsi?

Anthu ena amavutika kumeza mapiritsi. Kwa munthu wotere, mutha kumwa mankhwalawa motere:

1. Ikani supuni 4-8 za madzi (ma ounces awiri kapena anayi) mu kapu yoyera.

2. Onjezani mapiritsi anu a mankhwala ndipo muwasiye kwa mphindi pafupifupi 5.

3. Kenako, phwanyani zidutswazo bwino ndi supuni yoyera.

4. Sakanizani bwino ndipo imwani chisakanizocho chikasungunuka .

5. Kenako, onjezerani supuni zina ziwiri kapena zinayi (ma ounces 1-2) za madzi mu kapu yomweyo, tsukani supuni yomwe mwagwiritsa ntchito bwino, ndipo imwaninso madziwo. Izi ndizofunikira kuti mankhwala asatayike.

6. Chitani izi mpaka zidutswa zonse zitatha m'kapu.

Nanga bwanji ngati ndaphonya mlingo kapena kusanza?

• Ngati mwaphonya mlingo: Ngati mwaphonya mlingo, imwani mwamsanga mukakumbukira. Komabe, ngati nthawi yanu yadutsa maola oposa 9 , thawani mlingowo. Imwani mlingo wanu wotsatira panthawi yomwe mwakonza. Musamwe milingo iwiri nthawi imodzi.
• Ngati mukusanza: Ngati mukusanza mutamwa mankhwala, musamwenso piritsi lina. Imwani mlingo wanu wanthawi zonse pa nthawi yomwe mwakonza tsiku lotsatira.

Mankhwala ena omwe angagwirizane ndi mankhwalawa

Mankhwala ena omwe mukumwa angagwirizane ndi Alpelisib. Izi zitha kuwonjezera kapena kuchepetsa mphamvu ya Alpelisib, kapena kuwonjezera chiopsezo cha zotsatirapo zake. Choncho uzani dokotala wanu za chilichonse mwa izi:

• Mankhwala ena omwe amagwiritsidwa ntchito pa khunyu (monga carbamazepine, phenobarbital, phenytoin)
• Rifampin
• Wort wa St. John (iyi ndi mankhwala owonjezera a zitsamba)
• Warfarin (mankhwala ochepetsa magazi)

Zinthu zapadera zomwe muyenera kuzidziwa mukamamwa mankhwala

Muyenera kusamala pang'ono ndi kusintha kwa thupi lanu mukamamwa mankhwalawa.

• Pitani kwa dokotala wanu nthawi zonse: Dokotala wanu adzafunika kukuonani nthawi zonse kuti aone momwe chithandizocho chikukukhudzirani. Iyenso adzalamula kuti muyesedwe magazi. Musasiye mayeso aliwonse.
• Matenda aakulu a pakhungu:Mankhwalawa angayambitse mavuto aakulu pakhungu mwa anthu ena. Izi zitha kuchitika milungu ingapo kapena miyezi mutayamba kumwa mankhwala. Uzani dokotala wanu nthawi yomweyo ngati mukuyamba kutupa limodzi ndi zizindikiro monga malungo kapena kuzizira. Ziphuphu zimenezi zimatha kukhala zofiira kapena zofiirira, kenako ziphuphu ndipo khungu likhoza kuyamba kutseguka. Komanso, ngati muwona kufiira kulikonse pakhungu limodzi ndi kutupa kwa nkhope, milomo, kapena kutupa kwa khosi kapena m'khwapa, uzani dokotala wanu nthawi yomweyo.
• Kusowa madzi m'thupi: Uzani dokotala wanu ngati muli ndi kutsegula m'mimba kwambiri, nseru, kusanza, kapena thukuta kwambiri. Kutaya madzi ambiri m'thupi kungakhale koopsa mukamamwa mankhwalawa.
• Shuga wambiri m'magazi (Hyperglycemia): Mankhwalawa angayambitse shuga wambiri m'magazi. Chiwopsezochi chimakhala chachikulu kwa anthu omwe ali kale ndi matenda a shuga. Uzani dokotala wanu ngati muli ndi zizindikiro monga ludzu losazolowereka, kukodza pafupipafupi, kutopa kwambiri, kapena kusawona bwino .
• Mimba ndi kuyamwitsa:
• Kumwa mankhwalawa panthawi ya mimba kungayambitse mavuto aakulu kwa mwana wobadwa. Chifukwa chake, muyenera kuyezetsa kuti muwonetsetse kuti mulibe pakati musanayambe kulandira chithandizo.
• Muyenera kugwiritsa ntchito njira yothandiza kwambiri yolerera panthawi yonse yomwe mukumwa mapiritsi, komanso kwa sabata imodzi mutamwa mlingo womaliza .
• Ngati mnzanu watenga mimba, ndikofunikira kugwiritsa ntchito kondomu panthawi yogonana mukumwa mapiritsi komanso kwa sabata imodzi mutamwa mankhwala omaliza.
• Musayamwitse mwana pamene mukumwa mankhwalawa komanso kwa sabata imodzi mutamwa mankhwala omaliza.

Kodi zotsatirapo zake zingakhale zotani?

Monga mankhwala ena aliwonse, Alpelisib ingayambitse zotsatirapo zina. Zina mwa izi zingakhale zoopsa, choncho ndikofunikira kuzidziwa.

Chofunika: Mndandandawu suli ndi zotsatirapo zonse zomwe zingachitike. Ngati mukukumana ndi zizindikiro zachilendo, funsani upangiri kwa dokotala.

Kodi mumatani ngati mwamwa mankhwala ochulukirapo?

Ngati mukuganiza kuti mwamwa mankhwala ochulukirapo, pitani ku chipatala cha Emergency Unit (ETU) nthawi yomweyo. Kapena imbani National Poisons Information Centre ku Colombo National Hospital .

Kodi mumasunga ndi kutaya bwanji mankhwala mosamala?

• Kusunga: Nthawi zonse sungani mankhwala pamalo omwe ana ndi ziweto sangafikire . Kutentha kwa chipinda (pakati pa madigiri 20-25 Celsius) ndikobwino. Musagwiritse ntchito mankhwala otha ntchito.
• Kutaya: Funsani dokotala wanu za njira yabwino kwambiri yotayira mankhwala osagwiritsidwa ntchito kapena omwe atha ntchito. Mankhwala ena sayenera kutsukidwa m'chimbudzi. Ngati sizingatheke, mutha kuchotsa mapiritsiwo m'botolo, kuwasakaniza ndi zinthu monga khofi wogwiritsidwa ntchito, dothi, kapena zinyalala za amphaka, ndikuziyika m'thumba lotsekedwa bwino ndikuziyika m'zinyalala.