Kodi magazi anu amaundana mosavuta? Tiyeni tiphunzire za Kusowa kwa Antithrombin!

Ngakhale titakhala ndi bala laling'ono pathupi lathu, kutuluka magazi kumasiya pakapita nthawi ndipo magazi amaundana, sichoncho? Ndi njira yodabwitsa kwambiri yomwe thupi lathu limatetezera. Komabe, ngati magazi amaundana mopitirira muyeso, kapena ngati magazi amaundana mkati mwa thupi popanda chifukwa? Ndiye kuti zingakhale vuto. Lero tikambirana za chifukwa chapadera chomwe chimayambitsa magazi kuundana mosafunikira. Ndicho Antithrombin Deficiency , ena amachitchanso Antithrombin III Deficiency.

Kodi kwenikweni Antithrombin Deficiency ndi chiyani?

Mwachidule, kusowa kwa antithrombin ndi vuto lokhudzana ndi njira yathu yotsekera magazi. Pankhaniyi, pali kuchepa kwa puloteni yotchedwa antithrombin, chinthu chofunikira m'thupi lathu chomwe chimaletsa magazi kutsekeka kwambiri, kapena sichigwira ntchito bwino.

Taganizirani izi motere. Mukudzaza bafa ndi madzi. Winawake ayenera kuzimitsa pompo isanasefukire, apo ayi madzi onse adzatuluka. Umu ndi momwe, magazi athu akayamba kuuma, ndi chinthu chotchedwa antithrombin chomwe "chimaletsa" magazi panthawi yoyenera, ndikuletsa kuti asachitike kwambiri. Chifukwa chake, ngati mulibe antithrombin yokwanira m'thupi lanu, kapena ngati sichikugwira ntchito bwino, mutha kukhala ndi magazi oundana omwe amapitirira kuchitika, monga bafa yodzaza. Ichi ndichifukwa chake muli pachiwopsezo chachikulu chokhala ndi magazi oundana osazolowereka .

Anthu omwe ali ndi vutoli ali pachiwopsezo chachikulu chotenga magazi m'mitsempha yakuya ya miyendo (`Deep Vein Thrombosis` kapena `DVT`) komanso chiopsezo chakuti magazi amaundana n'kutsekeka m'mitsempha m'mapapo (`Pulmonary Embolism` kapena `PE`) . Izi zitha kukhala zoopsa kwambiri.

Kodi vutoli ndi lofala bwanji?

Kusowa kwa Antithrombin kwenikweni ndi vuto losowa kwambiri . Akuti munthu m'modzi yekha mwa anthu 2,000 mpaka 3,000 ali ndi vutoli. Izi sizikutanthauza kuti sizichitika kwa aliyense.

Kodi zizindikiro za kusowa kwa antithrombin ndi ziti?

Si aliyense amene ali ndi vutoli amene ali ndi zizindikiro zofanana. Anthu ena sangakhale ndi zizindikiro zilizonse. Komabe, nthawi zambiri magazi amayamba kuundana asanakwanitse zaka 40 .

Zizindikiro zomwe zimaonekera kwambiri ndi izi:

• Deep Vein Thrombosis (DVT): Izi zingayambitse mwendo kutupa, kufiira, kupweteka, komanso kumva kutentha ukakhudza.
• Kupuma kwa M'mapapo (PE): Izi zingayambitse kupuma movutikira mwadzidzidzi, kupweteka pachifuwa (makamaka popuma), kupuma mofulumira, kukhosomola (nthawi zina ndi magazi), komanso kupuma movutikira. Ili ndi vuto lomwe limafuna chithandizo chadzidzidzi.

Kuwonjezera pa izi, ngakhale kawirikawiri, m'mitsempha ya ubongo , kapena m'mitsempha ya m'mimbaPali kuthekera kwa magazi kuundana.

Chifukwa chiyani kusowa kwa antithrombin kumeneku kumachitika?

Nthawi zambiri, chomwe chimayambitsa vutoli chimakhala majini , kutanthauza kuti ndi chinthu chomwe timalandira kuchokera kwa makolo athu.

• Kusintha kwa Majini: Kusowa kwa Antithrombin kumachitika mwa anthu omwe ali ndi kusintha kwa majini otchedwa `SERPINC1`. Jini iyi imalangiza thupi kupanga antithrombin.
• Cholowa: Mutha kulandira kusintha kwa majini kuchokera kwa kholo lililonse. Ngati ndi choncho, muli ndi mwayi wa 50% wokhala ndi vutoli. Zilibe kanthu kaya ndi mtsikana kapena mnyamata. Komabe, makanda omwe amalandira kusintha kwa majini kuchokera kwa makolo onse awiri nthawi zambiri sakhala ndi moyo. Izi zimachitika kawirikawiri.

Chofunika ndichakuti si aliyense amene ali ndi kusintha kwa majini kumeneku amene amakhala ndi magazi oundana. Anthu ena akhoza kukhala moyo wawo wonse popanda mavuto.

Kodi madokotala amazindikira bwanji izi?

Ngati muli ndi zizindikiro izi, kapena mukudziwa kuti wina m'banja mwanu ali ndi vutoli, ndi bwino kupita kwa dokotala kukayezetsa. Dokotala nthawi zambiri amachita izi:

• Kuyezetsa thupi: Thupi lanu lidzayezetsedwa.
• Mbiri ya matenda: Mudzafunsidwa za zizindikiro zanu komanso ngati pali wina aliyense m'banja mwanu amene wakhala ndi mavuto ofanana ndi anu.
• Kuyezetsa magazi: Chofunika kwambiri ndikuchita kuyezetsa magazi kwapadera komwe kumayesa kuchuluka kwa antithrombin m'magazi anu.

Mayeso awa ndi njira yokhayo yotsimikizira ngati vutoli lilipo kapena ayi.

Mukuchita chiyani ngati chithandizo?

Chithandizocho chimadalira ngati muli ndi magazi oundana kapena ayi.

• Ngati muli ndi magazi oundana: Dokotala wanu angasankhe kuyamba kumwa mankhwala ochepetsa magazi . Mankhwalawa nthawi zambiri amakhala warfarin (mwina munamvapo kuti ndi Coumadin). Izi zingatenge miyezi ingapo, kapena moyo wanu wonse.
• Ngati simunakhalepo ndi magazi oundana: Ngakhale mutakhala ndi vuto la antithrombin, ngati simunakhalepo ndi magazi oundana, nthawi zambiri simuyenera kupitiriza kumwa mankhwala ochepetsa magazi. Komabe, nthawi zina (monga opaleshoni yayikulu isanachitike) angapatsidwe kwa nthawi yochepa.
• Pa nthawi ya mimba: Popeza pakati pa 3% ndi 50% ya amayi apakati omwe ali ndi vutoli amatha kukha magazi ambiri panthawi ya mimba, dokotala angasankhe kupereka jakisoni wa mankhwala otchedwa `Heparin` kuti magazi asaundane panthawiyo.

Kodi ndiyenera kudzisamalira bwanji? (Ndikulandira chithandizo)

Ngati mukumwa mankhwala ochepetsa magazi monga Warfarin kapena Heparin, ndikofunikira kwambiri kumwa mankhwalawo monga momwe dokotala wanu wanenera.Komanso, onetsetsani kuti mukupita kukaonana ndi dokotala nthawi iliyonse yomwe mungakhale nayo.

Popeza mankhwalawa ali ndi chiopsezo chotaya magazi, dokotala wanu ayenera nthawi zonse kuwonetsetsa kuti mwalandira mlingo woyenera. Mayeso a magazi monga mayeso a `Prothrombin Time` (PT) amagwiritsidwa ntchito kutsimikizira ngati mlingo wa Warfarin ndi wolondola.

Mwa kuwongolera bwino mlingo wa mankhwala mwanjira imeneyi, magazi owuma oopsa amatha kupewedwa ndipo kutuluka magazi kosafunikira kungapewedwe.

Kodi ndingachite chiyani kuti ndichepetse chiopsezo cha magazi kuundana?

Ngati muli ndi vuto la antithrombin, pali zinthu zingapo zomwe mungachite kuti muchepetse chiopsezo chanu cha magazi kuundana:

• Pewani kumwa mapiritsi oletsa kubereka: makamaka omwe ali ndi estrogen. Lankhulani ndi dokotala wanu za izi.
• Pewani mankhwala a mahomoni: Mankhwala ena a mahomoni omwe amatengedwa pambuyo pa kusamba amathanso kuwonjezera chiopsezo.
• Musakhale pamalo omwewo kwa nthawi yayitali: Makamaka mukayenda mtunda wautali kapena kugwira ntchito pamalo amodzi kwa nthawi yayitali, imirirani osachepera maola awiri aliwonse ndipo yendani pang'ono ndikugwedeza miyendo yanu.
• Musasute fodya ndi kugwiritsa ntchito zinthu zopangidwa ndi fodya: Kusuta fodya kumawononga kwambiri mitsempha yamagazi ndipo kumawonjezera kwambiri chiopsezo cha magazi kuundana.
• Khalani ndi kulemera kwabwino: Kunenepa kwambiri ndi chifukwa china chomwe chimayambitsa magazi kuundana.

Kuphatikiza apo, zinthu monga kuvulala kwakukulu, opaleshoni, mimba, kubereka, ndi ukalamba zimawonjezeranso chiopsezo cha magazi kuundana. Ngati mukufuna opaleshoni kapena mukuyembekezera mwana, uzani dokotala wanu za vuto lanu. Angakupatseni jakisoni wapadera wa antithrombin ngati jakisoni wa m'mitsempha (IV), ngati pakufunika.

Kodi pali njira yopewera vutoli?

Mwatsoka, popeza ndi matenda a majini, palibe njira yopewera kusowa kwa antithrombin komwe timalandira . Sitingathe kusintha majini omwe timalandira kuchokera kwa makolo athu. Komabe, pali zinthu zomwe tingachite kuti tichepetse chiopsezo cha magazi kuundana.

Kodi mungayembekezere chiyani ngati muli ndi vuto la antithrombin?

Pafupifupi munthu m'modzi mwa anthu atatu aliwonse omwe ali ndi vutoli amakhala ndi magazi oundana akakula.

• Opaleshoni ndi kusayenda: Ngati mukuchitidwa opaleshoni ndipo simukuyenda kwa nthawi yayitali (monga ngati muyenera kukhala pabedi), muli pachiwopsezo chachikulu chotenga magazi kuundana.
• Ukalamba: Chiwopsezochi chimawonjezekanso pang'ono ndi ukalamba.
• Mimba: Anthu omwe ali ndi vuto la antithrombin amatha kukhala ndi magazi oundana nthawi ya mimba kapena atabereka, choncho chisamaliro chapadera chiyenera kuperekedwa pa izi.

Kodi vutoli lidzatha liti?

Chifukwa ndi matenda a majini, mumabadwa nawo. Ndi chinthu chomwe chimakhalapo kwa moyo wonse. Izi zikutanthauza kuti sichingachiritsidwe kwathunthu. Koma, ngati mutachisamalira bwino, mutha kukhala ndi mavuto ochepa.

Kodi chiyembekezo cha vutoli n'chiyani?

Kaonedwe kanu ka zinthu kamadalira ngati mwakhala ndi magazi oundana kapena ayi. Kumwa mankhwala ochepetsa magazi kungathandize kupewa magazi ena oundana. Komabe, ndikofunikira kumwa mankhwalawo monga momwe dokotala wanu wanenera, pa mlingo woyenera, komanso nthawi yoyenera.

Ndiyenera kusamala kwambiri ndi chiyani?

Ngati muli ndi vuto la antithrombin, ndikofunikira kudziwa zizindikiro zochenjeza za `DVT` (magazi kuundana mwendo) ndi `PE` (magazi kuundana m'mapapo) kuti mupeze thandizo mwachangu.

• Zizindikiro za DVT: kutupa, kupweteka, kufiira, ndi kutentha kukakhudza mwendo umodzi (nthawi zambiri mwendo umodzi).
• Zizindikiro za PE: Kupuma movutikira, kupweteka pachifuwa (komwe kumakulirakulira mukapuma), kupuma mofulumira, kupuma movutikira, chifuwa (nthawi zina ndi magazi).

Ngati mukumwa mankhwala ochepetsa magazi (monga Warfarin), dziwani izi chifukwa pali chiopsezo chotaya magazi:

• Samalani kwambiri mukamagwiritsa ntchito zida zakuthwa (mipeni, malezala, ndi zina zotero)
• Pewani masewera omwe angayambitse kuvulala (monga rugby, nkhonya) momwe mungathere. Apo ayi, valani zovala zoyenera zodzitetezera.
• Ngati kutuluka magazi sikutha ngakhale pa bala lokha, kapena ngati mukuyamba kuvulala popanda chifukwa, uzani dokotala wanu.

Ndiyenera kupita kwa dokotala liti?

Ngati mukuganiza kuti muli ndi DVT, pitani kwa dokotala nthawi yomweyo. Ndikofunikira kuchiza DVT mwachangu, chifukwa magazi oundana mwendo amatha kusweka ndikupita ku mapapo, zomwe zimapangitsa kuti PE ichitike.

Ngati mukumwa mankhwala monga Warfarin, ngati mwagwa, kapena ngati mwatuluka magazi osazolowereka (monga kuchokera m'mphuno, m'kamwa, kapena m'chimbudzi), uzani dokotala wanu nthawi yomweyo.

Kodi ndi liti pamene muyenera kupita ku Emergency Treatment Unit (ETU) ?

Mu mkhalidwe wotere , muyenera kupita ku chipatala nthawi yomweyo ku Emergency Treatment Unit (ETU) :

• Ngati muli ndi zizindikiro za `Pulmonary Embolism (PE)` (monga kupuma movutikira, kupweteka pachifuwa).
• Bwanji ngati mukuganiza kuti muli ndi zizindikiro za DVT , koma simungathe kulankhulana ndi dokotala wanu?
• Ngati mukumwa mankhwala ochepetsa magazi, ngati mwagunda mutu, ngati mukusanza magazi, kapena ngati simungathe kuletsa kutuluka magazi kuchokera pabala.

Izi ndi zoopsa zomwe zingawononge moyo, choncho musazengereze.

Kodi ndi mafunso otani ofunika omwe ndiyenera kufunsa dokotala wanga?

Mukadziwa kuti muli ndi vutoli, mutha kufunsa dokotala wanu mafunso monga awa:

• Kodi ndiyenera kumwa Warfarin kapena mankhwala ena ochepetsa magazi? Kodi ndiyenera kumwa nthawi yayitali bwanji?
• Kodi ndi bwino kupita kwa achibale anga ena (makolo, abale, ana) kukayezetsa ngati ali ndi vuto la kuchepa kwa magazi m'thupi?
• Ndi masewera olimbitsa thupi ati omwe ndingachite mosamala ndi vutoli?
• Kodi pali zinthu zina zapadera zomwe ndiyenera kudziwa ndisanayambe kutenga mimba?

Funsani mafunso ngati awa kuti mumvetse bwino za vuto lanu.

Pomaliza, zinthu zomwe muyenera kukumbukira (Uthenga Wopita Nawo Kunyumba)

Popeza Kusowa kwa Antithrombin ndi vuto la majini, sitingathe kuliletsa. Komabe, podziwa vutoli ndikuchitapo kanthu kofunikira, mutha kukhala ndi moyo wathanzi kwambiri.

Chofunika kwambiri ndichakuti inu ndi banja lanu mudziwe zizindikiro zochenjeza za DVT ndi PE kuti ngati china chake chalakwika, mutha kuzindikira msanga ndikupeza chithandizo mwachangu.

Kulamulira kulemera kwanu, kuchita masewera olimbitsa thupi nthawi zonse, komanso kupewa kusuta kungakuthandizeni kuchepetsa chiopsezo chanu chokhala ndi magazi ambiri osafunikira. Mwanjira imeneyi, mutha kuwongolera momwe vutoli limakhudzira moyo wanu mpaka pamlingo winawake. Lankhulani ndi dokotala wanu nthawi zonse ndipo tsatirani malangizo ake mosamala. Musadandaule, simuli nokha!

` kusowa kwa antithrombin, magazi kuundana, DVT, pulmonary embolism, matenda a majini, kuchepetsa magazi, warfarin, heparin